Annals of Oncology最新文献

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77P Predictive biomarkers for cetuximab-based rechallenge in metastatic colorectal cancer: A pooled analysis of CAVE and CAVE-2 studies 基于西妥昔单抗的转移性结直肠癌再挑战的预测性生物标志物:CAVE和CAVE-2研究的汇总分析
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.078
D. Ciardiello, G. Martini, G. Pennoni, A. Avallone, S. Pisconti, G. Santabarbara, T.P. Latiano, G. Tortora, A. Sartore Bianchi, C. Cremolini, M.G. Zampino, C. Pinto, N. Normanno, T. Troiani, F. De Vita, N. Fazio, E. Martinelli, F. Ciardiello, S. Napolitano
{"title":"77P Predictive biomarkers for cetuximab-based rechallenge in metastatic colorectal cancer: A pooled analysis of CAVE and CAVE-2 studies","authors":"D. Ciardiello, G. Martini, G. Pennoni, A. Avallone, S. Pisconti, G. Santabarbara, T.P. Latiano, G. Tortora, A. Sartore Bianchi, C. Cremolini, M.G. Zampino, C. Pinto, N. Normanno, T. Troiani, F. De Vita, N. Fazio, E. Martinelli, F. Ciardiello, S. Napolitano","doi":"10.1016/j.annonc.2026.05.078","DOIUrl":"10.1016/j.annonc.2026.05.078","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S29"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
73P Longitudinal tracking of circulating tumour DNA in patients with colorectal cancer: Using digital droplet PCR to track KRAS and BRAF driver mutations 73P纵向跟踪结肠直肠癌患者循环肿瘤DNA:使用数字液滴PCR跟踪KRAS和BRAF驱动突变
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.074
M.R. Openshaw, Y. Petrenko, E. Efstathiou, N. Tovey, A.A. Ptasinska, L. Ames, H.L. Robbins, L. Tee, J. Stockton, A.D. Beggs
{"title":"73P Longitudinal tracking of circulating tumour DNA in patients with colorectal cancer: Using digital droplet PCR to track KRAS and BRAF driver mutations","authors":"M.R. Openshaw, Y. Petrenko, E. Efstathiou, N. Tovey, A.A. Ptasinska, L. Ames, H.L. Robbins, L. Tee, J. Stockton, A.D. Beggs","doi":"10.1016/j.annonc.2026.05.074","DOIUrl":"10.1016/j.annonc.2026.05.074","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S27"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
98P Comparison of three-component and two-component chemotherapy regimens in patients with isolated unresectable and potentially resectable colorectal cancer liver metastases: Results of a retrospective study 一项回顾性研究的结果:三组分和双组分化疗方案在孤立的不可切除和潜在可切除的结直肠癌肝转移患者中的比较
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.099
G.G. Makiev, R.S. Abdulaeva, A. Rays, M. Manukyan, E. Timofeeva, A. Ivanova, D. Lipatov, A. Polyakov, O. Egenov, E.D. Aleksandrov, A. Gorokhov, A.Y. Kashcheeva, K. Lezina, A. Tyrko, D. Halafyan, M.Y. Fedyanin, A.A. Tryakin
{"title":"98P Comparison of three-component and two-component chemotherapy regimens in patients with isolated unresectable and potentially resectable colorectal cancer liver metastases: Results of a retrospective study","authors":"G.G. Makiev, R.S. Abdulaeva, A. Rays, M. Manukyan, E. Timofeeva, A. Ivanova, D. Lipatov, A. Polyakov, O. Egenov, E.D. Aleksandrov, A. Gorokhov, A.Y. Kashcheeva, K. Lezina, A. Tyrko, D. Halafyan, M.Y. Fedyanin, A.A. Tryakin","doi":"10.1016/j.annonc.2026.05.099","DOIUrl":"10.1016/j.annonc.2026.05.099","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S38"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
38P Clinical utility of PET-CT in the management of colorectal liver metastases PET-CT在结直肠肝转移治疗中的临床应用
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.041
D.W. McMorrough, N. Ryan, M. Godson Treacy, J. Mulsow, A. Rogers, H.M. Fenlon, D. Cowzer
{"title":"38P Clinical utility of PET-CT in the management of colorectal liver metastases","authors":"D.W. McMorrough, N. Ryan, M. Godson Treacy, J. Mulsow, A. Rogers, H.M. Fenlon, D. Cowzer","doi":"10.1016/j.annonc.2026.05.041","DOIUrl":"10.1016/j.annonc.2026.05.041","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S16"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
81P Urinary extracellular vesicle-based liquid biopsy for minimal residual disease detection in colorectal cancer: Analytical validation and updated prognostic analysis with extended follow-up 基于尿细胞外囊泡的液体活检用于结肠直肠癌的最小残留疾病检测:分析验证和延长随访的最新预后分析
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.082
T. Yamada, S. Kanaka, K. Uehara, Y. Yokoyama, G. Takahashi, T. Iwai, K. Takeda, K. Ueda, S. Kuriyama, T. Miyasaka, T. Matsui, K. Hayashi, S. Shinji, H. Sonoda, R. Ohta, A. Matsuda
{"title":"81P Urinary extracellular vesicle-based liquid biopsy for minimal residual disease detection in colorectal cancer: Analytical validation and updated prognostic analysis with extended follow-up","authors":"T. Yamada, S. Kanaka, K. Uehara, Y. Yokoyama, G. Takahashi, T. Iwai, K. Takeda, K. Ueda, S. Kuriyama, T. Miyasaka, T. Matsui, K. Hayashi, S. Shinji, H. Sonoda, R. Ohta, A. Matsuda","doi":"10.1016/j.annonc.2026.05.082","DOIUrl":"10.1016/j.annonc.2026.05.082","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S30"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
51P Oestrogen receptor β expression in colorectal cancer: Exploring sex-related differences of prognostic impact and association with tumour T cell infiltration 51P雌激素受体β在结直肠癌中的表达:探讨预后影响的性别差异及其与肿瘤T细胞浸润的关系
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.053
I.A. Norrgård, J. Kasurinen, H. Mustonen, J. Hagström, I. Beilmann-Lehtonen, C. Haglund, T. Kaprio, C. Böckelman, M. Sund
{"title":"51P Oestrogen receptor β expression in colorectal cancer: Exploring sex-related differences of prognostic impact and association with tumour T cell infiltration","authors":"I.A. Norrgård, J. Kasurinen, H. Mustonen, J. Hagström, I. Beilmann-Lehtonen, C. Haglund, T. Kaprio, C. Böckelman, M. Sund","doi":"10.1016/j.annonc.2026.05.053","DOIUrl":"10.1016/j.annonc.2026.05.053","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S20"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148529617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
93P Clinical utility of tissue-based negative hyper selection for optimizing targeted therapy in metastatic colorectal cancer 基于组织的阴性超选择优化转移性结直肠癌靶向治疗的临床应用
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.094
K. Suzuki, H. Osumi, O. Akira, I. Fukada, K. Yoshikawa, K. Yoshino, S. Udagawa, K. Shimozaki, M. Ogura, S. Fukuoka, T. Wakatsuki, K. Chin, S. Takahashi, S. Maeda, K. Yamaguchi, E. Shinozaki
{"title":"93P Clinical utility of tissue-based negative hyper selection for optimizing targeted therapy in metastatic colorectal cancer","authors":"K. Suzuki, H. Osumi, O. Akira, I. Fukada, K. Yoshikawa, K. Yoshino, S. Udagawa, K. Shimozaki, M. Ogura, S. Fukuoka, T. Wakatsuki, K. Chin, S. Takahashi, S. Maeda, K. Yamaguchi, E. Shinozaki","doi":"10.1016/j.annonc.2026.05.094","DOIUrl":"10.1016/j.annonc.2026.05.094","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S35"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148531862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3RO Treatment strategy and immune-related toxicity shape response to neoadjuvant immunotherapy in dMMR/MSI colorectal cancer: Results from the AGEO-NEO-MSI study dMMR/MSI结直肠癌新辅助免疫治疗的治疗策略和免疫相关毒性形态反应:来自AGEO-NEO-MSI研究的结果
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.007
A. Gandini, B. Doleschal, M.J. Overman, G.A.C. Rasschaert, P. Artru, M. Ambrosini, L. Salvatore, F.J. Ros Montana, A. De Cuyper, A. Puccini, A. Boileve, R. Desgrippes, A. Pastorino, S. Tamberi, A. Turpin, S. Lonardi, F. Sclafani, E.S. Bergen, J. Taieb
{"title":"3RO Treatment strategy and immune-related toxicity shape response to neoadjuvant immunotherapy in dMMR/MSI colorectal cancer: Results from the AGEO-NEO-MSI study","authors":"A. Gandini, B. Doleschal, M.J. Overman, G.A.C. Rasschaert, P. Artru, M. Ambrosini, L. Salvatore, F.J. Ros Montana, A. De Cuyper, A. Puccini, A. Boileve, R. Desgrippes, A. Pastorino, S. Tamberi, A. Turpin, S. Lonardi, F. Sclafani, E.S. Bergen, J. Taieb","doi":"10.1016/j.annonc.2026.05.007","DOIUrl":"10.1016/j.annonc.2026.05.007","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S4"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148531896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
37P Circulating tumor DNA (ctDNA) assays in the management of colorectal cancer (CRC): A snapshot of current US GI oncologist clinical investigator (CI) practice 37P循环肿瘤DNA (ctDNA)检测在结直肠癌(CRC)管理中的应用:当前美国GI肿瘤学家临床研究者(CI)实践的快照
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.040
N. Love, S. Wadehra, K. Pang, D. Paley, S.A. Cohen, N.A. Dasari, C.H. Lieu, K.A. Ziel, K. Miller, T. Cruse, L. Petelka
{"title":"37P Circulating tumor DNA (ctDNA) assays in the management of colorectal cancer (CRC): A snapshot of current US GI oncologist clinical investigator (CI) practice","authors":"N. Love, S. Wadehra, K. Pang, D. Paley, S.A. Cohen, N.A. Dasari, C.H. Lieu, K.A. Ziel, K. Miller, T. Cruse, L. Petelka","doi":"10.1016/j.annonc.2026.05.040","DOIUrl":"10.1016/j.annonc.2026.05.040","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S16"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148532015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
83P p53 status as a biomarker of outcomes in metastatic colorectal cancer treated with EGFR-targeted therapy: A propensity score matched RAXO analysis 83P p53状态作为egfr靶向治疗转移性结直肠癌预后的生物标志物:倾向评分匹配RAXO分析
IF 80.4 1区 医学
Annals of Oncology Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.annonc.2026.05.084
P.J. Osterlund, J. Koskinen, P.M.H. Nummela, I. Ukkola, E. Osterlund, M. Mäkinen, J. Sundström, V. Kärjä, J. Böhm, M. Ahtiainen, H. Isoniemi, A. Hosio, T. Salminen, K.I. Lehtomaki, A. Algars, R. Kallio, A. Lamminmäki, T. Pellinen, A. Ristimäki
{"title":"83P p53 status as a biomarker of outcomes in metastatic colorectal cancer treated with EGFR-targeted therapy: A propensity score matched RAXO analysis","authors":"P.J. Osterlund, J. Koskinen, P.M.H. Nummela, I. Ukkola, E. Osterlund, M. Mäkinen, J. Sundström, V. Kärjä, J. Böhm, M. Ahtiainen, H. Isoniemi, A. Hosio, T. Salminen, K.I. Lehtomaki, A. Algars, R. Kallio, A. Lamminmäki, T. Pellinen, A. Ristimäki","doi":"10.1016/j.annonc.2026.05.084","DOIUrl":"10.1016/j.annonc.2026.05.084","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"37 ","pages":"Page S31"},"PeriodicalIF":80.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148539795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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