Annales medico-psychologiques最新文献

{"title":"Diagnostiquer et traiter le TDAH et le trouble bipolaire comorbide chez l’adulte","authors":"Sara Cipriano Salvador Marques ,&nbsp;Clément Donde ,&nbsp;Antoine Bertrand ,&nbsp;Mircea Polosan ,&nbsp;Arnaud Pouchon","doi":"10.1016/j.amp.2024.08.025","DOIUrl":"10.1016/j.amp.2024.08.025","url":null,"abstract":"<div><h3>Objectives</h3><div>Attention deficit with or without hyperactivity disorder (ADHD) and bipolar disorder (BD) are two frequent adult psychiatric conditions with high rates of comorbidity. The existence of a symptom overlaps and the lack of knowledge of physicians concerning this double diagnosis can lead to underdiagnosis or to overdiagnosis of this comorbidity, which has a therapeutic and prognostic impact. The aim of this paper is to provide the information on how to screen, diagnose, and manage this comorbidity to the French-speaking practitioners.</div></div><div><h3>Methods</h3><div>We conducted a narrative review of literature to gather the updated information on how to differentiate between ADHD and BD, the specificities of the comorbidity, the existing screening and diagnostic tools, and the treatment approaches.</div></div><div><h3>Results</h3><div>During the clinical interview the practitioner needs to gather information regarding the age of symptoms onset, their evolution, and analyze in detail the signs and symptoms presented. Symptoms of ADHD are often present before 7 years old which is an age where BD is rare, and BD has a cyclical evolution, as opposed to ADHD which is a chronic condition. The symptomatic dimensions that overlap between ADHD and BD can be distinguished by an in-depth analysis. Depressive episodes, periods of libido increase and/or a reduced need for sleep, psychotic symptoms, and suicidal risk are in favor of BD and they are never present in ADHD. Regarding the comorbidity of ADHD and BD, many studies are in favor of a distinct entity with a separate clinical phenotype. This clinical phenotype is often marked by the early onset of mood episodes, a high frequency of mood episodes with mixed features, a BD that is partially resistant to pharmacological treatment, a history of violent behavior and suicide attempts, the presence of certain additional comorbidities, difficulties in socio-professional settings or a history of school difficulties. These characteristics can be considered as “red flags” that the practitioner should look out for. To correctly diagnose ADHD and BD comorbidity in adults, the practitioner must do a clinical assessment where he can use psychometric tools to support his clinical observation. The screening tools that can be used for BD are the Mood Disorder Questionnaire (MDQ) and the Hypomania CheckList (HCL-32). For ADHD there is the Adult ADHD Self-Report Scale (ASRS) and the Wender Utah Rating Scale (WURS). The use of a structured clinical interview such as the Mini International Neuropsychiatric Interview (MINI) or the Diagnostic Interview for ADHD in Adults (DIVA-5) can help to diagnose the conditions. Most of these tools are validated in French. The interest of neuropsychological testing in the screening and diagnosis of this comorbidity is limited, but it can be helpful in establishing a cognitive remediation treatment plan. The treatment of ADHD and BD comorbidity includes pharm","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 282-291"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pas si paradoxal … Neurobiologie du trouble déficit de l’attention–hyperactivité (TDAH) et mode d’action thérapeutique des psychostimulants","authors":"Benjamin Rolland ,&nbsp;Luc Zimmer ,&nbsp;Hugo Prunier ,&nbsp;Guillaume Sescousse","doi":"10.1016/j.amp.2024.09.002","DOIUrl":"10.1016/j.amp.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>Attention deficit hyperactivity disorder (ADHD) is characterized by impairments in attention and executive functions, potentially associated with hyperactivity and impulsivity. Psychostimulants, which have a dopaminergic action, are the main pharmacological class of drugs used to treat ADHD, both in adults and children. However, psychostimulant intoxication is known to cause attentional problems and psychomotor agitation. It may therefore seem paradoxical to treat ADHD symptoms with molecules whose use may cause the same type of symptoms.</div></div><div><h3>Methods</h3><div>In this narrative review, based on a selection of scientific articles, we aim to highlight how recent neurobiological data, addressing the dopaminergic mechanisms of attentional and executive functions, the dopaminergic abnormalities found in ADHD, as well as the pharmacological mode of action of psychostimulants, converge to explain this apparent paradox.</div></div><div><h3>Results</h3><div>For some fifteen years now, it has been suggested that there is an “inverted U-shape” relationship between dopamine levels in the prefrontal cortex (PFC) on the one hand, and attentional and executive performances on the other hand. Both too much and too little dopamine lead to the same result, i.e. disrupted executive functions and reduced cognitive performance. In ADHD, studies show that there is an abnormally low level of dopamine in the PFC, providing a potential explanation for ADHD symptomatology. Psychostimulants act primarily by blocking the presynaptic transporters of catecholamines (i.e., dopamine and noradrenaline). Thus, by raising dopamine levels in the CPF of subjects with ADHD, they bring them back to a range that supports adequate cognitive performance, whereas in subjects without ADHD, Psychostimulants are more likely to bring dopamine concentrations to high levels, where executive functions are also suboptimal.</div></div><div><h3>Conclusions</h3><div>The “inverted U-shape” model of the relationship between dopamine levels and attentional and executive performances elegantly resolves the apparent paradox of psychostimulant efficacy in ADHD, and helps explain a number of clinical situations frequently met in this disorder. It is important to educate patients, caregivers, as well as the media and the lay public, about these neurobiological explanations, especially to combat the frequent misrepresentations associated with the use of psychostimulants in ADHD.</div></div>","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 323-327"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risques du méthylphénidate au long cours","authors":"Lucie Jurek ,&nbsp;Samuele Cortese ,&nbsp;Mikail Nourredine","doi":"10.1016/j.amp.2024.08.027","DOIUrl":"10.1016/j.amp.2024.08.027","url":null,"abstract":"<div><div>The increasing administrative prevalence of Attention-Deficit Hyperactivity Disorder (ADHD) over recent years has correspondingly escalated the prescriptions of pharmacological treatments for ADHD, particularly methylphenidate (MPH), which remains the most extensively prescribed medication for this condition. In light of this trend, evaluating the long-term risks associated with using MPH is important. This article aims to present findings from studies concerning the long-term use of MPH, derived from a literature review of the past decade, primarily focusing on data sourced from PubMed to assess these risks. Our review has drawn on a diverse range of studies, including cohort studies, meta-analyses, and database reviews from various global regions, reflecting a comprehensive international perspective on the long-term safety of MPH. Our review highlights several key aspects. Initial worries about the adverse psychiatric effects of MPH did not find strong support in subsequent studies. Rather, the current body of literature suggests that MPH may have a protective effect against depression and substance use disorders. We found no significant increase in the likelihood of suicide or psychotic disorders among long-term users of MPH. In fact, studies indicate that MPH treatment might reduce the incidence of depression. Moreover, contrary to concerns that stimulant treatment might predispose individuals to SUDs, recent longitudinal studies have generally shown no increased risk of substance misuse. Some studies have even suggested a lower incidence of substance misuse among patients treated with MPH. The review also delved into cardiovascular risks, which have been a notable concern with long-term MPH usage. While short-term studies typically showed minimal cardiovascular risks, results on longer-term effects suggest potential increases in hypertension and other arterial diseases for a higher dosage, highlighting the necessity for careful cardiovascular monitoring in patients undergoing long-term treatment. No elevated risk was described concerning other cardiovascular diseases. Results regarding the impact on growth have been mixed. Some studies suggest a temporary reduction in growth velocity that normalizes over time. This pattern suggests a delayed, rather than permanently stunted, growth trajectory in children treated with MPH over the long term. Lastly, our review did not find any risk of testicular dysfunction in patients treated with MPH. The collective findings from the reviewed studies offer reassurance regarding several of the initial concerns about the long-term use of MPH. While there are concerns about potential hypertension and arterial disease risks and uncertainties regarding growth, it is important to regularly monitoring for patients using MPH. These findings should be communicated transparently to patients and their families, helping to inform shared decision-making about the initiation and continuation of MPH therapy for ","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 332-337"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TDAH en France : la place des associations de patients et familles","authors":"Christine Gétin,&nbsp;Claudine Casavecchia","doi":"10.1016/j.amp.2024.08.028","DOIUrl":"10.1016/j.amp.2024.08.028","url":null,"abstract":"<div><div>The patient association HyperSupers TDAH France, founded in 2002 and recognized as a public utility, plays a crucial role in supporting individuals with ADHD and their families. It provides personalized support, responding to over 11,000 requests in 2023, and educates the public through its vastly visited website. HyperSupers TDAH France also holds significant advocacy power. It has contributed to the development of the recommendations by the Haute Autorité de Santé – HAS – (French National Authority for Health) and actively participates in various health institutions to influence health policies. The association works in research, education, employment, and law to ensure recognition of ADHD and support for affected individuals. Collaborating with healthcare professionals and researchers, HyperSupers fosters a better understanding of ADHD and its management. It is actively involved in the national strategy on neurodevelopmental disorders (NDD). The association's main requests include establishing an ADHD research cohort, improving professional training, ensuring early diagnosis and interventions, and taking actions to enhance the academic and professional lives of individuals with ADHD. HyperSupers also advocates for changes in university curricula and for better consideration of the specific needs of individuals with ADHD in public policies.</div></div>","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 231-233"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial board + Ours","authors":"","doi":"10.1016/S0003-4487(25)00061-7","DOIUrl":"10.1016/S0003-4487(25)00061-7","url":null,"abstract":"","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Page ii"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infirmiers de pratique avancée dans le TDAH : l’exemple bastiais","authors":"Mélanie Guagenti,&nbsp;Laurence Bonelli","doi":"10.1016/j.amp.2024.09.020","DOIUrl":"10.1016/j.amp.2024.09.020","url":null,"abstract":"<div><h3>Background</h3><div>The profession of Advanced Practice Nurse (APN) has been rolling out since 2018 in France with the aim of improving access to care. In Corsica until 2021, there was no specialized structure for the identification and care of adults to ensure continuity of the care pathway for children diagnosed with ADHD who became adults, or to catch up with adults not diagnosed in childhood.</div></div><div><h3>Discussion</h3><div>The creation of an ADHD referral unit at the Bastia hospital was set up to guarantee equal access to care and prevent disruption of care in adulthood by offering a multiprofessional consultation. It received funding from the Fonds d’Innovation Organisationnel en Psychiatrie in December 2022. The establishment of this unit is based on collaboration, via an organizational protocol, between a psychiatrist and an APN specializing in Psychiatry and Mental Health (PMH), enabling the creation of an innovative care pathway. The main mission is to assess and treat ADHD, to confirm the diagnosis, assess the severity of disorders and comorbidities, and propose a personalized care plan. In terms of assessment, the IPA can carry out the first full clinical interview, analyze psychometric self-evaluation scales and administer the DIVA scale. The aim of this first interview is to take a very detailed history, and a biography going back to the perinatal period, early childhood, schooling, social/emotional life, and working life, as well as researching current repercussions. In terms of care, the IPA is responsible for referring patients requiring referral therapy to the cardiologist. After initiation of treatment by the psychiatrist, the IPA alternates with the physician to conduct follow-up clinical interviews. The aim of these follow-up consultations is to assess clinical condition and treatment efficacy, detect any side effects, monitor cardiovascular parameters and renew methylphenidate treatment. In addition to their clinical skills, the IPA also plays a coordinating role in the care of adults with ADHD. Their expertise in the field of psychiatry enables them to identify and optimize treatment in cases of dual pathologies. Their knowledge of the field and the network helps to create a city-hospital network, and to ensure the fluidity of a care pathway organized in collaboration with all the players involved. The IPA also brings added value to psycho-education initiatives, whether individual or group-based. In addition, the IPA can exercise clinical leadership by raising awareness of ADHD among student nurses and IDE colleagues. Finally, the IPA can become involved in clinical research on adult ADHD.</div></div><div><h3>Synthesis</h3><div>The Bastia experiment, which can easily be replicated, confirms that APN PMHs are innovative and valuable resources whose skills bring added value to the care of adults with ADHD.</div></div>","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 308-311"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TDAH en France : un défi en milieu scolaire","authors":"Sara Fally","doi":"10.1016/j.amp.2024.09.001","DOIUrl":"10.1016/j.amp.2024.09.001","url":null,"abstract":"<div><div>Attention deficit hyperactivity disorder (ADHD) often has a negative impact on schooling, affecting both learning and interpersonal relationships. How can we provide effective educational and behavioral support to children with ADHD at school? To achieve inclusive schooling, teachers combine intervention, support, and accommodation practices. However, due to the heterogeneity of ADHD symptoms, lack of teacher training, and limited practice evaluations, adaptations do not always meet the needs of affected students and can lead to discouragement. In this context, opting for an educational approach that benefits not only students with ADHD but also their peers as a whole would promote genuine inclusion.</div></div>","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 3","pages":"Pages 312-314"},"PeriodicalIF":0.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Évaluation de l’anosognosie et ses enjeux dans la maladie d’Alzheimer","authors":"Jean-Pierre Jacus ,&nbsp;Virginie Voltzenlogel ,&nbsp;Christine-Vanessa Cuervo-Lombard","doi":"10.1016/j.amp.2024.11.018","DOIUrl":"10.1016/j.amp.2024.11.018","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Anosognosia in the setting of Alzheimer's disease reduces the extent to which the subject can become involved in his or her care, it favors situations of danger, increases the distress of caregivers and increases the risk of early institutionalization. This explains why this symptom profile, which is common in the early stages of the pathology, has increasingly become a subject of research. Authors recall its definition, and the main models and assessment tools in Alzheimer's disease. These tools mostly relate to methods centered on the various dimensions of anosognosia. They concern a) the method of &lt;em&gt;patient–caregiver discrepancy&lt;/em&gt;, which assesses the levels of anosognosia by way of the differential between the opinion of the family caregiver and that of the subject concerning the competences or difficulties of the subject in various dimensions of daily living; b) the &lt;em&gt;prediction/performance discrepancy&lt;/em&gt;, which estimates the level of anosognosia from the discrepancy between the subject's predictions of success on different test items and his or her actual test results; and c) the &lt;em&gt;clinician assessment&lt;/em&gt; method, which calls on a professional to ascertain the patient's degree of anosognosia. Other methods described as patient-centered have appeared recently, in particular &lt;em&gt;phenomenological scales&lt;/em&gt; aiming to apprehend the experience of the subject by way of clinical interview, aiming to identify the processes and dimensions characterizing the condition. Anosognosia in Alzheimer's disease is positively associated with caregiver burden, overall cognitive decline, dysexecutive syndrome and apathy. It is negatively associated with depression, although this association is a subject of debate. The tools that have been validated in France are still too few [Antoine et al. (2004)], which explains the lack of interest in anosognosia in everyday clinical practice. Here again, there is no normative data to provide clinicians with some guidance. Recent research has underlined how anosognosia assessed by methods centered on dimensions (patient–caregiver discrepancies, prediction/performance discrepancies and clinician evaluation) is almost systematically associated with apathy, independently from the domains assessed (cognitive or behavioral disturbances, etc.). Thus, apathy appears as the most discriminant dimension in anosognosia according to the severity of the condition, which offers new perspectives for assessment in clinical practice. There are indeed numerous scales measuring apathy that have been validated in French, providing an evaluation by the family caregiver and the subject, and liable to generate an anosognosia index for the patient–caregiver discrepancy method. Depression, which is exacerbated by the awareness of disturbances, could raise the issue of denial, and more broadly of avoidance strategies, the implication of which in this symptom requires at least back-up by a causality between the two entities, and","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 2","pages":"Pages 178-184"},"PeriodicalIF":0.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abortion in South-Africa: Does a liberal legislation really impact safe access and use?","authors":"Robynn Hera ,&nbsp;Siposethu Nojoko ,&nbsp;Nancy Stiegler ,&nbsp;Jean Pierre Bouchard","doi":"10.1016/j.amp.2024.10.003","DOIUrl":"10.1016/j.amp.2024.10.003","url":null,"abstract":"<div><div>The World Health Organization (WHO) considers comprehensive abortion care as part of their essential healthcare service package, which includes the provision of information, abortion management, and post-abortion care. The WHO estimated that globally, 45% of all induced abortions were unsafe, and it noted that nearly half of all the abortions occurred under the least safe circumstances in Africa. Abortion has been legal in South Africa since the implementation of the Choice of Termination of Pregnancy (CTOP) Act (No. 92 of 1996), which was a significant departure from the country's previously restrictive abortion laws. While the CTOP Act (1996) has made provision for access to safe abortion services and pre- and post-abortion counselling, this has not been effectively implemented into effective service delivery. It's estimated that between 52% and 58% of abortions take place in informal medical settings, and that only 7% of the public health facilities in South Africa were performing abortion services in 2017. The WHO noted that the lack of access to safe, affordable, timely, and respectful abortion care, and the stigma associated with abortion pose risks to women's physical and mental well-being throughout the life-course. The aim of this paper was to explore how women in South Africa experience and cope with induced abortion. Additionally, this research looks at how religion, culture and stigma, impact abortion and mental health post-abortion of South African's women. This study utilises data from the latest South African Demographic and Health Surveys (SADHS), in 2016, which includes data from 8514 women aged 15-49 years. This study highlights the need for more data and research related to challenges and experiences of South African women around mental health and the nature of abortion within the country. In this interview conducted by Professor Jean-Pierre Bouchard, population analysts Robynn Ashely Hera and Siposethu Nojoko together with demographer Professor Nancy Stiegler from the University of the Western Cape discuss safe and unsafe abortion incidence and access and the psychological effects thereof.</div></div>","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 2","pages":"Pages 185-194"},"PeriodicalIF":0.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le vécu de la fratrie face au cancer pédiatrique : revue de la littérature systématique","authors":"Voskan Kirakosyan","doi":"10.1016/j.amp.2024.04.010","DOIUrl":"10.1016/j.amp.2024.04.010","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background and objectives&lt;/h3&gt;&lt;div&gt;Pediatric cancer presents numerous challenges for the afflicted child and their family. While the impact on the ill child and their parents has been well-documented, there has been limited research focusing on the experiences of siblings coping with a family member's cancer diagnosis. Existing French-language studies primarily examine how siblings adapt to pediatric cancer and the potential benefits of support groups tailored for them. To our knowledge, there is currently no French-language literature review addressing this specific topic. This article aims to conduct a systematic review of existing literature to analyze and synthesize key findings, thereby enhancing our understanding of siblings’ experiences in this context.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methodology&lt;/h3&gt;&lt;div&gt;We conducted a systematic review of both national and international articles published between 2012 and 2022, utilizing specific keywords. Searches were performed on databases including PubMed, PsycINFO, PsycARTICLES, and Google Scholar. Our methodology adhered to the PRISMA guidelines (Preferred Reporting Items for Systematic Review and Meta-Analyses). The quality of each included article was assessed using the Mixed Methods Appraisal Tool (MMAT). In presenting the results, we initially conducted a meta-synthesis of qualitative studies, which were then supplemented by quantitative and mixed data, taking into account their complementary nature. This approach offers a comprehensive overview of the existing findings.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Following the initial screening based on title and abstract, a total of 137 articles were identified. Upon thorough examination, 28 articles were deemed suitable for inclusion: comprising qualitative (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;12), quantitative (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;12), and mixed-methods (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;4) studies. Through analysis and synthesis of these findings, we gained a deeper insight into the experiences of siblings facing pediatric cancer. Subsequently, we provide an overview of the studies’ characteristics, their quality assessed using MMAT, and the demographic details of the siblings involved. This sets the stage for a meta-analysis of the results, offering a comprehensive examination of the collective findings. Several themes emerge to elucidate the experiences of siblings. “The onset of cancer” delves into the effects of receiving the diagnosis and the ensuing emotional turmoil, some of which may have enduring ramifications. Subsequent discussions encompass the myriad repercussions, shedding light on the pervasive changes across various aspects of life. Themes such as “Unequal care: being abandoned, forgotten by parents”; “The impact on family relationships”; “Taking on new responsibilities”; “The impact on friendships”; “The impact on school and education”; and “Being a donor for the sick child” intricately describe and address the siblings’ journey. The pres","PeriodicalId":7992,"journal":{"name":"Annales medico-psychologiques","volume":"183 2","pages":"Pages 154-171"},"PeriodicalIF":0.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}