Annals of parasitology最新文献_第9页

Rickettsiae among mustelids - new data from south-west Poland. mustelids中的立克次体——来自波兰西南部的新数据。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6803.468

Kacper Jurczyk, Katarzyna Buńkowska-Gawlik, Agnieszka Perec-Matysiak, Joanna Hildebrand

引用次数: 0

First record of Cotylurus metacercariae (Trematoda:Strigeidae) in Biomphalaria straminea (Planorbidae) from Argentina: morphological and molecular identification. 阿根廷水蚤(Planorbidae)中首次记录的囊蚴子叶虫(吸虫目:滴虫科):形态和分子鉴定。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6803.453

María V Fernández, Monika I Hamann, Carolina Davies, Juan J Lauthier, Dora Davies

{"title":"First record of Cotylurus metacercariae (Trematoda:Strigeidae) in Biomphalaria straminea (Planorbidae) from Argentina: morphological and molecular identification.","authors":"María V Fernández, Monika I Hamann, Carolina Davies, Juan J Lauthier, Dora Davies","doi":"10.17420/ap6803.453","DOIUrl":"https://doi.org/10.17420/ap6803.453","url":null,"abstract":"In the study of the biology of trematode species, the knowledge of the larval stages in snail hosts is important to elucidate their complete life cycle. The goal of the present study was to describe a new tetracotyle-type metacercaria found in the freshwater mollusk Biomphalaria straminea sampled in a rice field from Corrientes province, Argentina. To this end, 1,768 snails were collected from the cultivated plots and irrigated channels during the flooding periods (from the time of sowing to soon after rice harvesting) between December 2016 and May 2017. We used morphological and molecular analysis to characterize the tetracotyle-type metacercariae. Its morphological traits and the internal transcribed spacers (ITS1 and ITS2 plus 5.8S; ~1200 pb) from nuclear ribosomal DNA (rDNA) were amplified and sequenced. From 1,768 specimens of B. straminea screened, 52 were found infected with metacercariae of tetracotyle type (2.9%) that were identified as Cotylurus genus. A total of 218 metacercariae were found encysted in the ovotestis or between the mantle and viscera of B. straminea. Bioinformatic analysis showed that the metacercarial rDNA sequences shared 94% identity with those of Cotylurus gallinulae from Mexico and 100% identity with those of Cotylurus sp. from Brazil. In this study, the morphological descriptions are supplemented with the first molecular identification of a metacercaria related to Cotylurus parasitizing planorbids from Argentina. Also, our study provides a new morphological description in B. straminea, thus broadening the geographical distribution. The life cycle of this Cotylurus metacercariae is unknown and there are no reports of adult stages parasitizing waterfowl in Argentina.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"68 3","pages":"473-481"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10330343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Saliva and tear as useful tools for the diagnosis of Toxoplasma gondii in human specimens: a systematic review. 唾液和泪液作为诊断人类刚地弓形虫的有用工具:系统综述。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6802.426

Tooran Nayeri, Shahabeddin Sarvi, Ahmad Daryani

{"title":"Saliva and tear as useful tools for the diagnosis of Toxoplasma gondii in human specimens: a systematic review.","authors":"Tooran Nayeri, Shahabeddin Sarvi, Ahmad Daryani","doi":"10.17420/ap6802.426","DOIUrl":"https://doi.org/10.17420/ap6802.426","url":null,"abstract":"Toxoplasmosis is diagnosed by serology, mainly using invasive specimens such as serum or cerebrospinal fluid. This study aimed to investigate whether saliva and tear samples can be used instead of serum samples to diagnose Toxoplasma gondii. Five English-language databases were checked up to 2021. Other types of non-invasive samples (milk and urine) were excluded from this study. In 15 cross-sectional studies, a total of 4338 saliva samples were examined, out of which 718/3848 (18.66%), 30/200 (15%), and 60/122 (49.18%) samples were positive for anti-T. gondii IgG, IgM, and IgA antibodies, respectively. And for tear samples, a total of 723 samples in cross-sectional studies and 153 cases and 97 controls in case-control studies were included, out of which 199/538 (36.98%) and 155/247 (62.75%) samples were positive for anti-T. gondii IgG and IgA antibodies in cross-sectional studies and 86/128 (67.18%), 1/53 (1.88%), and 78/153 (50.98%) cases and 4/47 (8.51%), 0/47 (0%), and 12/97 (12.37%) controls were positive for anti-T. gondii IgG, IgM, and IgA antibodies in case-control studies, respectively. The results suggested that antibody levels in saliva and tear samples in humans could be useful for the diagnosis of toxoplasmosis, especially ocular toxoplasmosis using tear samples.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":" ","pages":"201-213"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40487030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of interleukin-6 and interleukin-1-β levels in patients with toxoplasmosis. 弓形虫病患者白细胞介素-6和白细胞介素-1-β水平的相关性

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6802.437

Murtada Hafedh Hussein, Moslim Mohsin Khalaf

{"title":"Association of interleukin-6 and interleukin-1-β levels in patients with toxoplasmosis.","authors":"Murtada Hafedh Hussein, Moslim Mohsin Khalaf","doi":"10.17420/ap6802.437","DOIUrl":"https://doi.org/10.17420/ap6802.437","url":null,"abstract":"Toxoplasmosis is an important disease, which is caused by obligate intracellular parasite Toxoplasma gondii. Maternal infection with toxoplasmosis during pregnancy is frequently stimulates the immune response that may cause the fetus to be lost or deformed. A case control study were conducted in Al-Nassiriya province, southern Iraq to measure the interleukin-6 and interleukin-1-β levels. One hundred and twenty seven recurrent aborted women suspected with toxoplasmosis attending to Bent Al-Huda Maternity and Child Hospital for the period from March 2020 to March 2021, and compared to (20) healthy women as a control group. The ages ranged between 16-42 years, 5 ml of blood samples were collected for serum detection positivity of latex agglutination test, Enzyme Linked immune sorbent assay (interleukin-6 and interleukin-1-β). The distribution analysis showed that the highest toxoplasmosis among aborted women compared to healthy control group, the infection rate were (39.37%). Higher percentages of toxoplasmosis (82.35%) was found within the age group (15-25) years. In addition, the results showed a high positive of toxoplasmosis in 43 cases out of 50 cases by latex agglutination test. Also, the result indicated increasing levels of IL-6 and IL-1-β in patients' sera (24.69, 14.21) respectively, compared to healthy women.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":" ","pages":"317-321"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40579629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Promising potent in vitro activity of curcumin and quercetin nano-niosomes against Trichomonas vaginalis. 姜黄素和槲皮素纳米小体体外抗阴道毛滴虫活性研究。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6802.432

Hajar Ziaei Hezarjaribi, Fatemeh Mollarostami, Pedram Ebrahimnejad, Bahman Rahimi Esboei, Mahdi Fakhar, Zaynab Sadeghi-Ghadi

{"title":"Promising potent in vitro activity of curcumin and quercetin nano-niosomes against Trichomonas vaginalis.","authors":"Hajar Ziaei Hezarjaribi, Fatemeh Mollarostami, Pedram Ebrahimnejad, Bahman Rahimi Esboei, Mahdi Fakhar, Zaynab Sadeghi-Ghadi","doi":"10.17420/ap6802.432","DOIUrl":"https://doi.org/10.17420/ap6802.432","url":null,"abstract":"Trichomonosis, caused by infection with a motile protozoan parasite called Trichomonas vaginalis, is the most common non-viral sexually transmitted disease worldwide. Since the 1960s, metronidazole has been used as a drug of choice. Considering increased resistance to anti-trichomonial drugs, alternative treatments are urgently needed. In this study, the standard strain of T. vaginalis was cultured in TYM medium. Curcumin and quercetin loaded with hyaluronic acid niosomes were prepared by the thin film hydration method. The mean vesicle size, polydispersity index, and zeta potential of each prepared formulation were characterized, and its anti-Trichomonas activity was assessed by concentrations of 0.01, 0.1, 1, 10 and 100 mg/ml. The cytotoxicity effects of the mentioned drugs were determined using a MTT assay on L929 fibroblast cell viability. The particle sizes of curcumin, quercetin, and curcumin-quercetin entrapped modified nano-niosomes were characterised as 243 ± 5.28, 223 ± 7.21 and 266 ± 4.81 nm. The results showed that quercetin and curcumin at a concentration of 100 mg/ml after 24 h had anti-T. vaginalis activity. However, curcumin at a concentration of 100 at time 3h with 97% growth inhibition had better performance than positive control (metronidazole). According to the results of the MTT assay, all drugs, even at the highest concentration (400 mg/ml), had no toxic effect on the fibroblast cell line. According to potent in vitro activity of curcumin and quercetin nanoniosomes against T. vaginalis in comparison with metronidazole, it can be concluded these compounds could be promising therapeutic candidates for trichomonosis in future.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":" ","pages":"263-273"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40601688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of chronic infection with toxoplasmosis in mitochondrial DNA 4,977 bp common deletion in sperm of men infertility. 弓形虫慢性感染在男性不育症精子线粒体 DNA 4,977 bp 常见缺失中的作用。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6804.500

Arshed Shakir Al-Khafaji, Ghada Basil Al-Omashi

{"title":"The role of chronic infection with toxoplasmosis in mitochondrial DNA 4,977 bp common deletion in sperm of men infertility.","authors":"Arshed Shakir Al-Khafaji, Ghada Basil Al-Omashi","doi":"10.17420/ap6804.500","DOIUrl":"https://doi.org/10.17420/ap6804.500","url":null,"abstract":"Toxoplasma has the ability to infect a wide range of living organisms, including humans, and the infection found all over the world. The current study included 200 blood and semen samples collected from married men from which 100 samples of infertile men and 100 non-infertile men as control. The infertile men were divided into two groups: group A, which includes 35 (35%) infertile patients have IgG antibody sero-positive with toxoplasmosis, and group B, which includes 65 (65%) infertile people without toxoplasmosis were detected by rapid test for Toxo IgG/IgM antibody and then ensure by enzyme linked sorbent immunoassay (ELISA). The aging of men involved in the study extended between 20-57 years. The study revealed group A Toxoplasma IgG positive have mean concentration 65.10±13.84, was measured by ELISA in the serum of patients. Studies have shown mean age of men in group A and group B patients were 32.77±7.83 and 30.31±6.14, respectively. The age from 20-29 years as well as from 30 to 39 years high number of infertility in both A and B group patients. There is no significant distribution between group A and group B patients according to age of men infertility. The common deletion 4,977 bp mutation in mitochondrial sperm DNA(mt-DNA) was detected using the Gap-polymerase chain reaction (PCR) technique. Although the results showed that group A have high rate of common deletion mutation compare to group B but non-significant, while there is no deletion detection in the control group. The current results showed that reducing the mean total number of sperms in group A patient common deletion high significant compared to group B. The mean percentage of slow movement high significant than group B patient but non-significant mean percentage of death sperm although have high mean than to group B patient and abnormal sperm shape percentage have significant is higher in group A patient (common deletion) compared to group B.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"68 4","pages":"887-896"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro toxicity of cinnamaldehyde and nanoemulsion of cinnamaldehyde on protoscoleces of hydatid cyst. 肉桂醛和肉桂醛纳米乳对包虫囊原头节的体外毒性研究。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6804.476

Azin Aghajani Amiri, Mohammad Reza Youssefi, Mohaddeseh Abouhosseini Tabari

{"title":"In vitro toxicity of cinnamaldehyde and nanoemulsion of cinnamaldehyde on protoscoleces of hydatid cyst.","authors":"Azin Aghajani Amiri, Mohammad Reza Youssefi, Mohaddeseh Abouhosseini Tabari","doi":"10.17420/ap6804.476","DOIUrl":"https://doi.org/10.17420/ap6804.476","url":null,"abstract":"Cystic echinococcosis is a major parasitic and zoonotic disease and surgery is the most common treatment of this disease which carries the risk of intraoperative leakage and recurrence. Using scolicidal agent to inactivate cyst contents reduces the risk of recurrence. Considering side effects of available scolicidals and growing interests on natural pharmaceuticals, the present study aimed to evaluate toxicity of cinnamaldehyde (CA), the main component of cinnamon essential oil, and a developed nanoemulsion of cinnamaldehyde (nano-CA) on protoscoleces of hydatid cyst. Nanoemulsion was prepared by the low energy system and characterized by dynamic light scattering to confirm dimensions. For evaluation of scolicidal effects, serial dilutions of CA and nano-CA were mixed with protoscolices suspension and mortality were recorded at 10, 30, and 60 minutes by eosin exclusion test. Albendazole was used as the positive control. The mean diameter of nano-CA was characterized as equal to 88.5 nm, and poly dispersity index was 0.09. After 30 min of treatment, nano-CA, at 50 μg/ml, killed 99.33% of protoscoleces. At the same time point and concentration, CA only caused mortality rate of 26.18%. 30 min-LC50 value of 369.39 μg/ml was obtained for CA, while after 30 min of exposure, nano-CA showed promising rapid activity with LC50 value of 3.22 μg/ml. Nano formulation significantly increased scolicidal activity of CA probably by increasing penetration and tegumental disorganization of protoscoleces. Further in vivo safety studies are needed to introduce nano-CA as a clinically applicable scolicidal agent.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"68 4","pages":"693-699"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10218534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Further contribution to the life history of Centrocestus formosanus (Nishigori, 1924) Price, 1932 (Trematoda: Heterophyidae) with special reference to a new first intermediate host from the South Western Ghats, India. 对台湾Centrocestus formosanus生活史的进一步贡献(Nishigori, 1924) Price, 1932(水螅目:异藻科)，特别提到了来自印度西南高止山脉的一个新的第一个中间寄主。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6804.482

Puthiyakandy Janardhanan Jithila, Kodungukudy Arusha, Puthanpurayil Kandambeth Prasadan, Joseph James Erinjery

引用次数: 0

A review of current treatment strategies based on cisplatin for leishmaniosis. 目前以顺铂为基础的利什曼病治疗策略综述。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6803.449

Heena Sachdeva, Manish Sharma

{"title":"A review of current treatment strategies based on cisplatin for leishmaniosis.","authors":"Heena Sachdeva, Manish Sharma","doi":"10.17420/ap6803.449","DOIUrl":"https://doi.org/10.17420/ap6803.449","url":null,"abstract":"Neglected tropical diseases as termed by World Health Organization include a group of 20 diverse infectious diseases in the tropical and subtropical regions of the world. Amongst these diseases, high mortality rate is mostly associated with Chagas disease and leishmaniosis due to limited drugs, severe toxicity caused by the available drugs and drug resistance. The above hitches have triggered the researchers to focus on the development of novel alternative therapeutics. Studies reveal that several target-based drugs have emerged which affect the biochemical pathways of the causative parasite. An anti-cancerous molecule and its derivatives might be used as antiprotozoal agents due to biochemical similarities affecting DNA metabolism. Cisplatin is a widely used drug for the treatment of testicular, ovarian, head and neck cancers, melanoma, lymphomas and several others. It exerts anticancer activity via multiple mechanisms but most effective mechanism is binding with DNA, formation of intrastrand and interstrand cross-links and generation of DNA lesions. However, side effects of cisplatin limit its application and effectiveness in the cancer treatment. Moreover, to minimize the side effects of cisplatin, combination therapies are used and have proven to be effective against cancers. Thus, current review is aimed at highlighting potential of cisplatin alone and in combination therapies as an antileishmanial agent.","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"68 3","pages":"435-445"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10705356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A scanning electron microscopic study of Argulus coregoni Thorell, 1866 (Crustacea: Branchiura) parasitizing Carassius auratus (Linnaeus, 1758) from India. 对寄生于印度鲫鱼（林尼厄斯，1758 年）的 Argulus coregoni Thorell, 1866（甲壳纲：Branchiura）的扫描电子显微镜研究。

Annals of parasitology Pub Date : 2022-01-01 DOI: 10.17420/ap6804.496

Nida Khwaja, Amit Tripathi

引用次数: 0