Anesthesiology最新文献

{"title":"Mind the GAP: Observing Adverse Effects in Clinical Trials.","authors":"Karsten Bartels,Mark C Bicket","doi":"10.1097/aln.0000000000005656","DOIUrl":"https://doi.org/10.1097/aln.0000000000005656","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"23 1","pages":"805-807"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Race, Ethnicity, and Antiemetic Management: Comment.","authors":"Mahmut Sami Tutar,Betul Kozanhan,Munise Yildiz","doi":"10.1097/aln.0000000000005642","DOIUrl":"https://doi.org/10.1097/aln.0000000000005642","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"53 1","pages":"1133"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Care of Patients with Wearable Cardioverter Defibrillators.","authors":"Kyle R Gashler,Joshua B Cohen,Thomas R Powell","doi":"10.1097/aln.0000000000005653","DOIUrl":"https://doi.org/10.1097/aln.0000000000005653","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"13 1","pages":"1026-1027"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal Protamine Dosing during Drug Shortages: Reply.","authors":"Michael Fabbro,Pankaj Jain,Richard H Epstein","doi":"10.1097/aln.0000000000005619","DOIUrl":"https://doi.org/10.1097/aln.0000000000005619","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"35 1","pages":"1132-1133"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cricoid Force: Anatomic, Physiologic, and Clinical Concepts.","authors":"Andreas Sotiriou,Imran Ahmad,Kariem El-Boghdadly","doi":"10.1097/aln.0000000000005558","DOIUrl":"https://doi.org/10.1097/aln.0000000000005558","url":null,"abstract":"The application of cricoid force remains controversial in modern practice. This review critically assesses the anatomic, physiologic, and contemporary clinical evidence of cricoid force application. There may be a sound anatomic basis to cricoid force application, involving occlusion of the postcricoid hypopharynx, but the physiologic basis is uncertain. Clinical evidence to date has not reliably determined efficacy of cricoid force application, largely because of inconsistent localization and application. Modern evidence suggests no clinically relevant implications to successful intubation with cricoid force application, particularly when videolaryngoscopy is used. Paralaryngeal force application demonstrates promise, but the evidence remains insufficient to globally change practice. Overall, the authors found uncertainty regarding the contemporary role of the application of cricoid force; however, when performed, it may be improved by localization of the cricoid cartilage using ultrasound, application of correct force by a trained assistant, and the use of videolaryngoscopy, although strong specific evidence is limited.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"75 1","pages":"1090-1110"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Use of Nonopioid Analgesic Modes over Time in Inpatient and Outpatient Total Knee Arthroplasty.","authors":"Periklis Giannakis,John Saleeb,Alex Illescas,Sophia T Zhuang,Lisa Reisinger,Crispiana Cozowicz,Haoyan Zhong,Lazaros Poultsides,Jiabin Liu,Robert G Marx,Stavros G Memtsoudis,Jashvant Poeran","doi":"10.1097/aln.0000000000005638","DOIUrl":"https://doi.org/10.1097/aln.0000000000005638","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"57 1","pages":"1123-1126"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia: A Randomized Clinical Trial.","authors":"Sang-Hwan Ji,Pyoyoon Kang,Sung-Ae Cho,Jung-Bin Park,Young-Eun Jang,Eun-Hee Kim,Jin-Tae Kim,Hee-Soo Kim,Hee-Jeong Jung,Han-Ah Jung,Hyung-Chul Lee,Ji-Hyun Lee","doi":"10.1097/aln.0000000000005634","DOIUrl":"https://doi.org/10.1097/aln.0000000000005634","url":null,"abstract":"BACKGROUNDAnesthetic exposure in young children raises concerns about neurodevelopmental safety, with preclinical evidence suggesting potential neurotoxicity of volatile anesthetics. This study aimed to assess whether the combination of dexmedetomidine and remifentanil, by reducing sevoflurane exposure, has any differential effect on neurodevelopmental outcomes in young children compared with sevoflurane alone.METHODSThis study was a prospective, double-blind, randomized clinical trial including children younger than 2 yr undergoing nonstaged, nonrepetitive surgeries. Participants received dexmedetomidine and remifentanil as adjuncts to sevoflurane (DEX-R group) or sevoflurane alone (control group). The study assessed their neurodevelopmental status at 28 to 30 months using the Korean Leiter International Performance Scale and the Child Behavior Checklist, as predefined secondary outcomes. The primary endpoint-full-scale IQ at 5 yr of age-will be reported after completion of long-term follow-up.RESULTSAmong 400 enrolled participants, 343 completed assessments (169 control, 176 DEX-R). There was no difference in the mean anesthesia duration between the control and DEX-R groups (77.1 min vs. 72.8 min; mean difference [95% CI], 4.4 [-3.8 to 12.6]; P = 0.293). The mean end-tidal sevoflurane concentration was significantly lower in the DEX-R group than in the control group (1.8 vol% vs. 2.6 vol%; mean difference [95% CI], -0.9 [-1.0 to -0.7] vol%; P < 0.001). The mean full-scale IQ score was 102.5 ± 11.5 in the DEX-R group and 103.6 ± 11.5 in the control group (mean difference, -1.1; 95% CI, -3.9 to 1.7; P = 0.442). No significant difference was observed in the Child Behavior Checklist total score between groups.CONCLUSIONSThe addition of dexmedetomidine and remifentanil to sevoflurane anesthesia was not associated with significant differences in neurodevelopmental outcomes at 28 to 30 months compared to sevoflurane alone.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"37 1","pages":"827-834"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turning the Spotlight on the Supramammillary Nucleus: A Key Structure to Accelerate Arousal from General Anesthesia?","authors":"Wei Mei,Laszlo Vutskits","doi":"10.1097/aln.0000000000005641","DOIUrl":"https://doi.org/10.1097/aln.0000000000005641","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"71 1","pages":"813-815"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kate Leslie AO FAHMS, Recipient of the 2025 Award for Excellence in Research.","authors":"David Story","doi":"10.1097/aln.0000000000005639","DOIUrl":"https://doi.org/10.1097/aln.0000000000005639","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"33 1","pages":"823-824"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Management of the Patient Receiving Maintenance Hemodialysis.","authors":"Vikram Fielding-Singh,Pavel S Roshanov,Arden M Morris,Glenn M Chertow","doi":"10.1097/aln.0000000000005581","DOIUrl":"https://doi.org/10.1097/aln.0000000000005581","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"38 1","pages":"1030-1048"},"PeriodicalIF":8.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}