Anesthesiology最新文献

{"title":"A Mechanical Strategy for Preventing Perioperative Pulmonary Aspiration.","authors":"Kevin R Olsen, Anastasia Jones, Alfonso Pepe","doi":"10.1097/ALN.0000000000006198","DOIUrl":"10.1097/ALN.0000000000006198","url":null,"abstract":"<p><p>Pulmonary aspiration of gastric contents is a rare but serious complication of impaired consciousness, such as during the induction of anesthesia, and is associated with significant morbidity and mortality. Despite numerous standard interventions, there is limited evidence that these strategies reliably prevent aspiration. Alginates are naturally derived polysaccharides that form a buoyant gel \"raft\" barrier in the stomach and have been used safely for decades to prevent acid reflux worldwide. However, according to the scientific literature, alginates have not been employed to potentially prevent pulmonary aspiration of gastric contents during induction of anesthesia and represent a promising new prophylactic option, serving as an ingestible physical barrier to esophageal reflux of stomach contents. With established safety and efficacy in the treatment of gastroesophageal reflux disease, alginates may offer an immediate, nonsystemic, inert, and safe reflux barrier to limit the risk of aspiration by physically inhibiting the regurgitation of gastric contents.</p>","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"831-835"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reassessing Local Anesthetic and Adjuvant Mixtures: Comment.","authors":"Daniel Brosius, Alexandra Hart, Veena Graff, Taras Grosh","doi":"10.1097/ALN.0000000000006248","DOIUrl":"10.1097/ALN.0000000000006248","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"145 4","pages":"1072-1073"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148918066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Multimodal Analgesia Succeeds, Do Regional Blocks Still Have Value?","authors":"Kara M Barnett, Kelly Lebak","doi":"10.1097/ALN.0000000000006271","DOIUrl":"10.1097/ALN.0000000000006271","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"145 4","pages":"818-820"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148918123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reassessing Local Anesthetic and Adjuvant Mixtures: Comment.","authors":"Matthias Thoma","doi":"10.1097/ALN.0000000000006249","DOIUrl":"10.1097/ALN.0000000000006249","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"145 4","pages":"1075-1076"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148918094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holger K. Eltzschig, M.D., Ph.D., Recipient of the 2026 Award for Excellence in Research.","authors":"Alex S Evers","doi":"10.1097/ALN.0000000000006230","DOIUrl":"https://doi.org/10.1097/ALN.0000000000006230","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"145 4","pages":"842-844"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway Management Risks in Pediatric Anesthesia: Comment.","authors":"Yasin Tire, Bedia Mine Hanedan, Bülent Hanedan, Abdullah Celep","doi":"10.1097/ALN.0000000000005988","DOIUrl":"10.1097/ALN.0000000000005988","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"1056-1057"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147508853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia Workstation Performance in Pediatric Ventilation: Part 1. Precision of Ventilation.","authors":"Johannes Spaeth, Malte Trost, Bernd Flamm, Christin Wenzel, Stefan Schumann","doi":"10.1097/ALN.0000000000006149","DOIUrl":"10.1097/ALN.0000000000006149","url":null,"abstract":"<p><strong>Background: </strong>Mechanical ventilation of children sets the highest demands on the performance of anesthesia workstations. Different ventilator technologies are available, each representing unique pneumatic characteristics. The hypothesis of this study was that precision of delivered ventilation parameters depends on the ventilator type.</p><p><strong>Methods: </strong>Six modern anesthesia workstations (GE HealthCare Carestation 650; Mindray Bio-Medical Electronics Co. Ltd. Wato EX-65 Pro and A9; Dräger Medical Atlan A350 and Perseus A500; and Getinge Flow-c) were tested in physical models simulating the respiratory systems of a preterm baby, a neonate, an infant, and a toddler. Volume-controlled and pressure-controlled ventilation were investigated with and without airway leakage. Delivered tidal volume, peak inspiratory pressure, positive end-expiratory pressure, and inspiratory to expiratory ratio were compared to the set values. The data are presented descriptively; a difference greater than or equal to 10% between the delivered and set values was considered clinically relevant.</p><p><strong>Results: </strong>Deviations of the delivered volume from the set tidal volume during volume-controlled ventilation ranged between -19.5 ± 0.6% and +35.1 ± 3.0% in the preterm baby model but decreased with increasing tidal volume. Positive end-expiratory pressure and peak inspiratory pressure during pressure-controlled ventilation did not differ relevantly from the set values in any device or lung model. Expiratory ratios varied widely in most devices, leading to relevant differences in tidal volume during pressure-controlled ventilation. With leakage, tidal volume was, on average, 7% lower during volume-controlled ventilation but 2% lower during pressure-controlled ventilation.</p><p><strong>Conclusions: </strong>Precision of ventilation with modern anesthesia workstations varies depending on the ventilator type, ventilation mode, and set parameters. Pressure-controlled ventilation is advantageous in the six workstations tested considering the good agreement between the applied and the set parameters and leakage compensation. The results imply precision superiority of pressure-controlled ventilation over volume-controlled ventilation in preterm babies and neonates, independent from the ventilator technology in use.</p>","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"942-953"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147925688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected Failure of Bronchial Blocker Placement Due to an Undiagnosed Tracheal Bronchus.","authors":"Xiangyi Kong, Yan Zhang, Longfei Wang, Penghui Wei","doi":"10.1097/ALN.0000000000006206","DOIUrl":"10.1097/ALN.0000000000006206","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"1006-1007"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow- versus Pressure-controlled Ventilation: Comment.","authors":"Chih-Wen Wang, Cheng-Wei Lu","doi":"10.1097/ALN.0000000000006219","DOIUrl":"10.1097/ALN.0000000000006219","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"1059-1060"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitric Oxide and Kidney Injury after Heart Surgery: Comment.","authors":"Nikolay O Kamenshchikov, Mark A Tyo, Igor V Kravchenko, Elena A Churilina, Maxim S Kozulin, Yuri K Podoksenov, Chong Lei","doi":"10.1097/ALN.0000000000006228","DOIUrl":"10.1097/ALN.0000000000006228","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"1064-1065"},"PeriodicalIF":9.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}