Anesthesiology最新文献

{"title":"Serratus Anterior Plane Block for Lung Resection: Comment.","authors":"Fabricio A Lasso Andrade","doi":"10.1097/aln.0000000000005536","DOIUrl":"https://doi.org/10.1097/aln.0000000000005536","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"687 1","pages":"477-478"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Plexus Blocks and Persistent Pain: Reply.","authors":"Min Zeng,Shu Li,Daniel I Sessler,Yuming Peng","doi":"10.1097/aln.0000000000005510","DOIUrl":"https://doi.org/10.1097/aln.0000000000005510","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"109 1","pages":"473-474"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes Mellitus in Pregnancy: Implications for Obstetric Anesthesia.","authors":"W Kirke Rogers,Iryna Chugaieva,Amir Moheet,Sarah A Wernimont","doi":"10.1097/aln.0000000000005534","DOIUrl":"https://doi.org/10.1097/aln.0000000000005534","url":null,"abstract":"Diabetes in pregnancy is a common obstetric comorbidity that increases the risks of pregnancy-specific complications. The authors describe in this review how understanding ambulatory use of insulin can impact peripartum anesthesia care. Additionally, they describe the appropriate delivery, dosing, and timing of insulin during birth as relevant for anesthesiologists. They discuss the indications and limitations of technologies such as continuous glucose monitors and insulin pumps in pregnancy, and describe their relevance and appropriate management in the perioperative and peripartum period. Finally, the authors review the unique complication of euglycemic diabetic ketoacidosis and provide appropriate management strategies, as anesthesiologists may be in a position to recognize this complication that could otherwise be overlooked.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"21 1","pages":"424-443"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitric Oxide and Kidney Injury after Cardiac Surgery: A Solution Looking for a Problem.","authors":"Vikram Fielding-Singh,Kamrouz Ghadimi","doi":"10.1097/aln.0000000000005545","DOIUrl":"https://doi.org/10.1097/aln.0000000000005545","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"687 1","pages":"247-249"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Memory Meets Pain: Divergent Neural Signatures of Sedative Agents.","authors":"Zirui Huang","doi":"10.1097/aln.0000000000005555","DOIUrl":"https://doi.org/10.1097/aln.0000000000005555","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"32 1","pages":"253-254"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serratus Anterior Plane Block for Lung Resection: Comment.","authors":"Pinguo Fu","doi":"10.1097/aln.0000000000005540","DOIUrl":"https://doi.org/10.1097/aln.0000000000005540","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"8 1","pages":"482-483"},"PeriodicalIF":8.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse events associated with airway management in pediatric anesthesia: A prospective, multicenter, observational Japan Pediatric Difficult Airway in Anesthesia (J-PEDIA) study.","authors":"Taiki Kojima,Yusuke Yamauchi,Fumio Watanabe,Shogo Ichiyanagi,Yasuma Kobayashi,Yu Kaiho,Hiroaki Toyama,Shugo Kasuya,Norifumi Kuratani,Yasuyuki Suzuki","doi":"10.1097/aln.0000000000005646","DOIUrl":"https://doi.org/10.1097/aln.0000000000005646","url":null,"abstract":"BACKGROUNDThe incidence of adverse events and desaturation during airway-securing procedures (a sequence from preoxygenation to completion of tracheal intubation or supraglottic airway placement) under general anesthesia in children remains underexplored. Thus, we investigated the incidence of adverse and desaturation events and associated risk factors.METHODSThis was a prospective, multicenter, observational study conducted between June 2022 and January 2024 in 10 tertiary care (six pediatric and four university [mixed adult-pediatric]) hospitals in Japan. A standardized data collection system was applied through the recruited institutions to collect ≥95% of cases. The primary and secondary outcomes were adverse events and a ≥10% drop in oxygen saturation (desaturation) associated with airway-securing procedures.RESULTSThere were 17007 airway management procedures in 16695 children (mean age 6.3 years, standard deviation 4.8). Any adverse events occurred in 346/17007 (2.0%; 95% CI, 1.8-2.3) children, including 189/17007 (1.1%; 0.96-1.3) respiratory adverse events. Desaturation occurred during 395/17007 (2.3%; 2.1-2.6) procedures, with 66/308 (21.4%; 17.0-26.4) in neonates and 210/2298 (9.1%; 8.0-10.4) in infants. Multilevel regression analysis showed younger age (adjusted odds ratio 0.92, 95% CI, 0.90-0.95; p<0.001), airway management in radiation diagnostic/therapy rooms (5.7, 1.64-19.9; p=0.006), airway sensitivity (1.46, 1.09-1.94; P=0.010), craniocervical surgery (1.41, 1.09-1.83; p=0.009), and presence of 1 or ≥2 anatomical difficult airway features (1.74, 1.02-2.95; p=0.042 and 2.82, 1.21-6.6; p=0.017, respectively) as risk factors of any adverse events. Supraglottic airway device usage at the first attempt and muscle relaxant administration (0.42, 0.288-0.62; p<0.001 and 0.62, 0.43-0.89; p=0.009, respectively) showed a beneficial effect.CONCLUSIONSThe J-PEDIA study demonstrated adverse event and desaturation incidences and the impact of clinically relevant risk factors during airway-securing procedures in Asian children. This study can help anesthesiologists to identify high-risk children and create a safe airway-securing strategy.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"9 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of increased cardiopulmonary bypass pump flow on renal filtration, perfusion, oxygenation and tubular injury in cardiac surgical patients - a randomized controlled trial.","authors":"Johanna Wijk,Anna Cordefeldt-Keiller,Gudrun Bragadottir,Bengt Redfors,Sven-Erik Ricksten,Lukas Lannemyr","doi":"10.1097/aln.0000000000005648","DOIUrl":"https://doi.org/10.1097/aln.0000000000005648","url":null,"abstract":"BACKGROUNDCardiac surgery with cardiopulmonary bypass (CPB) is associated with impaired renal oxygenation and acute kidney injury. We investigated whether a higher than our standard blood flow during CPB could improve renal blood flow, oxygen demand/supply relationship, function and attenuate tubular injury.METHODSAfter ethical approval and informed consent, 36 adult patients undergoing cardiac surgery received either high-flow (2.9 L/min/m2, n=19) or standard-flow (2.4 L/min/m2, n=17) during CPB in this randomized, non-blinded, parallell-arm study. Systemic hemodynamics and renal variables were measured before and during CPB. Glomerular filtration rate was measured by infusion clearance of iohexol and renal blood flow by infusion clearance of para-aminohippuric acid, corrected for renal extraction of para-aminohippuric acid, using a renal vein catheter. Renal oxygen demand/supply relationship was estimated from renal oxygen extraction and tubular injury assessed by urinary N-acetyl-β-D-glucosaminidase.RESULTSDuring CPB, high-flow lead to a larger increase in systemic oxygen delivery (100 ml/min/m2, 95% CI [60;141], vs 31[1.9;65], between group p<0.001, effect size Cohen´s dz 0.59) and target mean arterial pressure was maintained at a lower norepinephrine dose (0.03 µg/kg/min [-0.01;0.06] vs 0.10 [0.02;0.19], p=0.048, Cohen´s dz=0.62) compared with standard-flow. There were no differences in renal blood flow or oxygen extraction between groups. Glomerular filtration rate increased during high-flow CPB (6.4 ml/min/1.73m2 [1.9;10.9]), but not in the standard-flow group (-2.3 [-10.9;6.2], between group p=0.044, Cohen´s dz 0.66). The peak urinary excretion of N-acetyl-β-D-glucosaminidase was 1.42 units/µmol creatinine [0.87,3.6] vs 3.74 [1.5,7.7] in the high-flow and standard-flow groups, respectively (p=0.049). No perfusion-related adverse events were seen in either group.CONCLUSIONSA 20% higher than standard CPB flow during cardiac surgery improved renal function while no change in renal blood flow or oxygen demand/supply relationship could be detected. Higher CPB flow was associated with a less pronounced tubular injury marker release compared with standard flow.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"3 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the U.S. Food and Drug Administration's Safety Communication on Gabapentinoid-Opioid Coprescription.","authors":"Periklis Giannakis, Alex Illescas, Lisa Reisinger, Haoyan Zhong, Crispiana Cozowicz, Lazaros Poultsides, Jiabin Liu, Jashvant Poeran, Stavros G Memtsoudis","doi":"10.1097/ALN.0000000000005564","DOIUrl":"https://doi.org/10.1097/ALN.0000000000005564","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assisted Fluid Management for Major Liver Surgery: Comment.","authors":"Enrico Giustiniano, Maxim Neganov, Fulvio Nisi","doi":"10.1097/ALN.0000000000005472","DOIUrl":"10.1097/ALN.0000000000005472","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"224-225"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}