Anesthesiology最新文献

{"title":"Assisted Fluid Management for Major Liver Surgery: Comment.","authors":"Qian Tang, Guangmin Xu","doi":"10.1097/ALN.0000000000005471","DOIUrl":"10.1097/ALN.0000000000005471","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"222-224"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombin Generation Assay in Pediatric Cardiac Surgery: A Prediction Tool or Not Ready for Prime Time?","authors":"Kenichi A Tanaka, Kenneth E Stewart, Jerrold H Levy","doi":"10.1097/ALN.0000000000005522","DOIUrl":"10.1097/ALN.0000000000005522","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"15-17"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Global and Regional Connectivity in Propofol-induced Unconsciousness: Human Intracranial Electroencephalography Study.","authors":"Mikyung Choe, Yunhee Choi, Jii Kwon, Hee-Pyoung Park, Seung-Hyun Jin, June Sic Kim, Seokhyun Lee, Chun Kee Chung","doi":"10.1097/ALN.0000000000005479","DOIUrl":"10.1097/ALN.0000000000005479","url":null,"abstract":"<p><strong>Background: </strong>The conscious state is maintained through intact communication between brain regions. However, studies on global and regional connectivity changes in unconscious state have been inconsistent. These inconsistencies could arise from unclear definition of unconsciousness, spatial and temporal limitations of neuroimaging modalities, and estimating only single connectivity measure. This study investigated global and regional changes in amplitude and phase-based functional connectivity in propofol-induced unconsciousness, which is widely recognized as unconsciousness.</p><p><strong>Methods: </strong>Amplitude and phase-based functional connectivity was calculated using amplitude envelope correlation, weighted phase lag index, and magnitude squared coherence from intracranial electroencephalography data of 73 patients. Global changes in connectivity, complexity, and network efficiency were estimated. Regional connectivity changes between Brodmann areas, between seven cortical lobes, and between resting state networks were assessed across all frequency bands. Additionally, machine learning analysis was employed to identify specific regions in classifying conscious and unconscious states.</p><p><strong>Results: </strong>In the unconscious state, global connectivity increased across all frequency bands, while global complexity and efficiency decreased, accompanied by increased delta and decreased high gamma power spectral density. Regional connectivity increased between entire cortical regions across all frequency bands. Machine learning analysis revealed that posterior connectivity was the most influential in classifying consciousness. Amplitude-based connectivity predominantly increased in the delta and theta bands, while phase-based connectivity predominantly increased from the beta to high gamma bands.</p><p><strong>Conclusions: </strong>Propofol anesthesia suppresses cortical activity and induces oscillatory changes characterized by increased delta power and decreased high gamma power. These changes are accompanied by increased functional connectivity and reduced network complexity and efficiency. These changes limit the brain's ability to generate a diverse repertoire of activity, ultimately leading to unconsciousness. Posterior connectivity, which showed high accuracy in predicting conscious states, would be crucial for sustaining consciousness.</p>","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":"114-131"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Care of Older Adults: Comment.","authors":"Ronald Hirsch","doi":"10.1097/ALN.0000000000005484","DOIUrl":"10.1097/ALN.0000000000005484","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"229-230"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid, Safe, and Efficient Reduction in the Carbon Footprint of Preoperative Travel: A Nationwide Study.","authors":"Karthik Raghunathan, Pattrapun Wongsripuemtet, Atilio Barbeito, Marc J Pepin, Vijay Krishnamoorthy, Tetsu Ohnuma, Julien Cobert, Seshadri Mudumbai, Rohil Watwe, William T Bryan","doi":"10.1097/ALN.0000000000005466","DOIUrl":"10.1097/ALN.0000000000005466","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"209-212"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assisted Fluid Management for Major Liver Surgery: Reply.","authors":"Sean Coeckelenbergh, Maxim Soucy-Proulx, Tristan Grogan, Maxime Cannesson, Alexandre Joosten","doi":"10.1097/ALN.0000000000005474","DOIUrl":"10.1097/ALN.0000000000005474","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"226-228"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bug in the Syndrome: Using the Gut Microbiome to Diagnose Complex Regional Pain Syndrome.","authors":"Zulmary Manjarres, Ashley N Plumb, Katelyn E Sadler","doi":"10.1097/ALN.0000000000005488","DOIUrl":"10.1097/ALN.0000000000005488","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"20-21"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Making Safe Blood Safer: A Swing and a Miss.","authors":"Richard P Dutton","doi":"10.1097/ALN.0000000000005504","DOIUrl":"10.1097/ALN.0000000000005504","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"18-19"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polygenic Risk for Postoperative Nausea and Vomiting: Reply.","authors":"Nicholas J Douville, Lisa Bastarache, Brett Vanderwerff, Emily Bertucci-Richter, Ida Surakka, Miklos D Kertai","doi":"10.1097/ALN.0000000000005491","DOIUrl":"10.1097/ALN.0000000000005491","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"232-233"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony.","authors":"Craig M Palmer, Peter H Pan","doi":"10.1097/ALN.0000000000005513","DOIUrl":"10.1097/ALN.0000000000005513","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"143 1","pages":"4-5"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}