AnesthesiologyPub Date : 2024-11-01DOI: 10.1097/aln.0000000000005191
Jennifer Lucero,Gail A Van Norman
{"title":"Keeping the Patient at the Center of Conscientious Objection while Respecting Our Colleagues.","authors":"Jennifer Lucero,Gail A Van Norman","doi":"10.1097/aln.0000000000005191","DOIUrl":"https://doi.org/10.1097/aln.0000000000005191","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"7 1","pages":"822-824"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-11-01DOI: 10.1097/aln.0000000000005132
Gerardo Tusman,Cecilia M Acosta,Fernando Suarez Sipmann
{"title":"Lung Strain during Laparoscopies in Children: Reply.","authors":"Gerardo Tusman,Cecilia M Acosta,Fernando Suarez Sipmann","doi":"10.1097/aln.0000000000005132","DOIUrl":"https://doi.org/10.1097/aln.0000000000005132","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"53 1","pages":"1021-1022"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-11-01DOI: 10.1097/aln.0000000000005164
Megha Karkera Kanjia,C Dean Kurth,Daniel Hyman,Eric Williams,Anna Varughese
{"title":"Perspectives on Anesthesia and Perioperative Patient Safety: Past, Present, and Future.","authors":"Megha Karkera Kanjia,C Dean Kurth,Daniel Hyman,Eric Williams,Anna Varughese","doi":"10.1097/aln.0000000000005164","DOIUrl":"https://doi.org/10.1097/aln.0000000000005164","url":null,"abstract":"During the past 70 years, patient safety science has evolved through four organizational frameworks known as Safety-0, Safety -1, Safety-2, and Safety-3. Their evolution reflects the realization over time that blaming people, chasing errors, fixing one-offs, and regulation would not create the desired patient safety. In Safety-0, the oldest framework, harm events arise from clinician failure; event prevention relies on better staffing, education, and basic standards. In Safety-1, used by hospitals, harm events arise from individual and/or system failures. Safety is improved through analytics, workplace culture, high reliability principles, technology, and quality improvement. Safety-2 emphasizes clinicians' adaptability to prevent harm events in an everchanging environment, using resilience engineering principles. Safety-3, used by aviation, adds system design and control elements to Safety-1 and Safety-2, deploying human factors, design-thinking, and operational control or feedback to prevent and respond to harm events. Safety-3 represents a potential way for anesthesia and perioperative care to become safer.","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"41 1","pages":"835-848"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-11-01DOI: 10.1097/aln.0000000000005189
Richard P Dutton
{"title":"Tactics versus Strategy in Trauma Resuscitation.","authors":"Richard P Dutton","doi":"10.1097/aln.0000000000005189","DOIUrl":"https://doi.org/10.1097/aln.0000000000005189","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":"55 1","pages":"832-834"},"PeriodicalIF":8.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-10-30DOI: 10.1097/ALN.0000000000005203
Lealani Mae Y Acosta
{"title":"The Notes Are for Us.","authors":"Lealani Mae Y Acosta","doi":"10.1097/ALN.0000000000005203","DOIUrl":"https://doi.org/10.1097/ALN.0000000000005203","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-10-30DOI: 10.1097/ALN.0000000000005283
Jai N Darvall, Anurika P De Silva, Britta von Ungern-Sternberg, David A Story, Andrew J Davidson, Megan L Allen, An Tran-Duy, Cindy Schultz-Ferguson, Vi Ha, Sabine Braat, Kate Leslie
{"title":"Chewing gum to treat postoperative nausea and vomiting in female patients: a multicenter randomized trial.","authors":"Jai N Darvall, Anurika P De Silva, Britta von Ungern-Sternberg, David A Story, Andrew J Davidson, Megan L Allen, An Tran-Duy, Cindy Schultz-Ferguson, Vi Ha, Sabine Braat, Kate Leslie","doi":"10.1097/ALN.0000000000005283","DOIUrl":"https://doi.org/10.1097/ALN.0000000000005283","url":null,"abstract":"<p><strong>Background: </strong>Postoperative nausea and vomiting (PONV) is common after general anesthesia, with consequences for patient outcomes, satisfaction with care and healthcare costs. Our aim was to compare a new treatment, chewing gum, with a widely-used intravenous agent, ondansetron, to treat PONV in female patients in the post anesthesia care unit (PACU).</p><p><strong>Methods: </strong>We conducted a multicenter, randomized, controlled non-inferiority trial in 17 hospitals in Australia and New Zealand. Female patients aged ≥12 years undergoing volatile anesthetic-based general anesthesia for laparoscopic or breast surgery were enrolled. Protocolized anti-emetic prophylaxis was administered. Patients who developed PONV in the PACU were randomized to either 15 min of chewing gum or 4 mg of intravenous ondansetron. The primary outcome was cessation of nausea, retching or vomiting, with no recurrence nor rescue medication for 2 h after administration of the randomized intervention (i.e., complete response).</p><p><strong>Results: </strong>Of 865 enrolled patients, 218 were randomized. In a per-protocol analysis, 50 of 105 (47.6%) ondansetron-treated patients compared with 31 of 103 (30.1%) chewing gum-treated patients achieved the primary outcome (absolute risk difference [95% confidence interval (CI)] -17.3 [-30.4 to -4.3] %), not reaching our prespecified non-inferiority limit. Time to complete response was longer for patients randomized to chewing gum (hazard ratio [95% CI] 0.53 [0.34, 0.83]), and they were more likely to receive antiemetics in the 24 h after surgery (absolute risk difference [95% CI] 14.07 [1.65, 26.49]).</p><p><strong>Conclusions: </strong>Chewing gum cannot be recommended as an alternative to ondansetron for treatment of PONV in female patients administered antiemetic prophylaxis.</p>","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnesthesiologyPub Date : 2024-10-30DOI: 10.1097/ALN.0000000000005230
Lidia Mora, Marc Maegele, Oliver Grottke, Andreas Koster, Philipp Stein, Jerrold H Levy, Gabor Erdoes
{"title":"Four-factor Prothrombin Complex Concentrate Use for Bleeding Management in Adult Trauma.","authors":"Lidia Mora, Marc Maegele, Oliver Grottke, Andreas Koster, Philipp Stein, Jerrold H Levy, Gabor Erdoes","doi":"10.1097/ALN.0000000000005230","DOIUrl":"https://doi.org/10.1097/ALN.0000000000005230","url":null,"abstract":"","PeriodicalId":7970,"journal":{"name":"Anesthesiology","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}