The Journal of maternal-fetal medicine最新文献

{"title":"Antibiotic prophylaxis at cesarean delivery","authors":"Joseph A. Spinnato,&nbsp;Brad Youkilis,&nbsp;Vernon D. Cook,&nbsp;Marcello Pietrantoni,&nbsp;Ann L. Clark,&nbsp;Stanley A. Gall","doi":"10.1002/1520-6661(200011/12)9:6<348::AID-MFM1005>3.0.CO;2-4","DOIUrl":"10.1002/1520-6661(200011/12)9:6<348::AID-MFM1005>3.0.CO;2-4","url":null,"abstract":"<div>\u0000 \u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Our aim was to compare the efficacy of ampicillin, cefotetan, and ampicillin/sulbactam in the prevention of post-Cesarean endomyometritis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consenting patients undergoing Cesarean delivery at the University of Louisville Hospital were enrolled in a prospective, double-blinded randomization to receive either ampicillin/sulbactam (Group 1), cefotetan (Group 2), or ampicillin (Group 3) single dose antibiotic prophylaxis following umbilical cord clamping. The primary outcome variable was the frequency of endomyometritis in the respective groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 301 randomized patients, outcome data was available for 298 patients. Fourteen patients (4.7%), all of whom underwent non-elective Cesarean delivery, developed endomyometritis. The frequency of endomyometritis was not different among groups: Group 1, 4/101 (4%); Group 2, 4/96 (4.2%); and Group 3, 6/101 (5.9%). Wound infections were infrequently observed 4/298 (1.3%) without significant differences among groups. Stepwise discriminative analysis identified only last cervical dilatation as a significant predictor of endomyometritis (<i>P</i> = 0.006).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Post-Cesarean endomyometritis occurs infrequently following single dose antibiotic prophylaxis after umbilical cord clamping. An advantage of broader spectrum antibiotics over ampicillin was not demonstrated. J. Matern.-Fetal Med. 2000;9:348–350. © 2000 Wiley-Liss, Inc.</p>\u0000 </section>\u0000 </div>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"348-350"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<348::AID-MFM1005>3.0.CO;2-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80372612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of FDA advisory on reported vacuum-assisted delivery and morbidity","authors":"Michael G. Ross,&nbsp;Meredith Fresquez,&nbsp;Mostafa A. El-Haddad","doi":"10.1002/1520-6661(200011/12)9:6<321::AID-MFM1000>3.0.CO;2-W","DOIUrl":"10.1002/1520-6661(200011/12)9:6<321::AID-MFM1000>3.0.CO;2-W","url":null,"abstract":"<div>\u0000 \u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>In May 1998 the US Food and Drug Administration (FDA) issued a health advisory reporting neonatal injuries/deaths following vacuum delivery and encouraged voluntary reports of future adverse events. We compared FDA reports of vacuum delivery adverse events prior to and following the advisory.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The FDA database (MAUDE) was searched for vacuum deliveries using brand name, manufacturer name, and procedure “string searches.” Cases were sorted by report date, source, and manufacturer. Neonatal morbidity was quantified as deaths and life-threatening or nonlife-threatening events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 80 reported adverse cases were identified after duplicate cases were consolidated. Twenty-five were reported to the FDA prior to the 1998 advisory and 55 in the immediate 6-month period following the advisory. There was a 22-fold increase in reported events from five events/year prior to the advisory to an estimated 110 events/year following the advisory. The distribution of reporting sources changed significantly following the advisory with increased “manufacturer” (8–43%) and decreased “voluntary” reports (56–20%). All major brand names were represented. During the 6 months following the FDA advisory there were 10 neonatal deaths, 30 life-threatening events, 12 nonlife-threatening events, and three equipment-related reports. Infant deaths were due to intracranial or subgaleal hematomas. Injuries included skull fracture, scalp abrasions, and cephalohematomas.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The FDA advisory was associated with a 22-fold increase in the rate of reported adverse events. This increase in reporting likely represents both enhanced awareness of complications as well as an increase in vacuum-related adverse neonatal sequelae. As vacuum delivery is associated with greater neonatal morbidity/mortality than was previously recognized, the adage that the vacuum is “designed to come off before infant damage occurs” appears unsubstantiated. It is recommended that manufacturers quantify the suction and traction capabilities of present and new proposed vacuum cup designs. J. Matern.-Fetal Med. 2000;9:321–326. © 2000 Wiley-Liss, Inc.</p>\u0000 </section>\u0000 </div>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"321-326"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<321::AID-MFM1000>3.0.CO;2-W","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73460236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dilatation of the left renal vein in preeclampsia","authors":"Naoki Tokunaga,&nbsp;Naohiro Kanayama,&nbsp;Motoi Sugimura,&nbsp;Takao Kobayashi,&nbsp;Toshihiko Terao","doi":"10.1002/1520-6661(200011/12)9:6<356::AID-MFM1007>3.0.CO;2-Y","DOIUrl":"10.1002/1520-6661(200011/12)9:6<356::AID-MFM1007>3.0.CO;2-Y","url":null,"abstract":"<div>\u0000 \u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Our purpose was to compare the morphological changes in renal veins during normal pregnancy and pregnancy involving preeclampsia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used ultrasonography to measure maximum diameters of the right and left renal veins, and the diameter of the left renal vein where it crosses the abdominal aorta in normal pregnancy and preeclampsia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In women with normal pregnancy, the maximum diameter of the left renal vein was 5.5 ± 1.9 mm in the 1st trimester, 5.8 ± 1.6 mm in the 2nd trimester, and 6.4 ± 1.4 mm in the 3rd trimester. The diameter of the left renal vein where it crosses the abdominal aorta was 3.3 ± 1.1 mm in the 1st trimester, 4.1 ± 1.3 mm in the 2nd trimester, and 4.0 ± 0.9 mm in the 3rd trimester. In contrast, the maximum diameter of the left renal vein in women that had preeclampsia with onset in the 2nd trimester was 9.8 ± 2.4 mm and that in women whose preeclampsia began in the 3rd trimester was 8.7 ± 1.6 mm. The diameter of the left renal vein in preeclampsia was significantly larger than that in normal pregnancy (<i>P</i> &lt; 0.05). There were no significant differences between normal pregnancy and preeclampsia in the maximum diameter of the right renal vein or that of the left renal vein where it crosses the abdominal aorta.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In preeclamptic women, a dilatation of the left renal vein was observed. This suggests that the relative constriction and congestion of the left renal vein takes part in the pathophysiology of preeclampsia. Measurement of the diameter of the left renal vein would provide a simple, cost-effective tool for the diagnosis of preeclampsia. J. Matern.-Fetal Med. 2000;9:356–359. © 2000 Wiley-Liss, Inc.</p>\u0000 </section>\u0000 </div>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"356-359"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<356::AID-MFM1007>3.0.CO;2-Y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79370908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant pleural mesothelioma in pregnancy","authors":"Patrick S. Ramsey,&nbsp;Diana R. Danilenko-Dixon,&nbsp;Kirk D. Ramin,&nbsp;Paul L. Ogburn Jr.","doi":"10.1002/1520-6661(200011/12)9:6<373::AID-MFM1012>3.0.CO;2-8","DOIUrl":"10.1002/1520-6661(200011/12)9:6<373::AID-MFM1012>3.0.CO;2-8","url":null,"abstract":"<p>A 37-year-old pregnant woman presented at 18 weeks' gestation with unrelenting chest and shoulder pain, massive pleural effusion, and a large thoracic mass. Biopsy revealed an undifferentiated sarcomatous pleural mesothelioma. Malignant mesothelioma is a rare thoracic malignancy, which has not been described in pregnancy and appears to be minimally affected by the pregnant state. J. Matern.-Fetal Med. 2000;9:373–375. © 2000 Wiley-Liss, Inc.</p>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"373-375"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<373::AID-MFM1012>3.0.CO;2-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85176797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late second stage rupture of the uterus and bladder with vaginal birth after cesarean section: A case report and review of the literature†","authors":"Joel C. Webb,&nbsp;George Gilson,&nbsp;Lakshmi Gordon","doi":"10.1002/1520-6661(200011/12)9:6<362::AID-MFM1009>3.0.CO;2-T","DOIUrl":"10.1002/1520-6661(200011/12)9:6<362::AID-MFM1009>3.0.CO;2-T","url":null,"abstract":"<p>Rupture of a uterine scar during labor with concomitant severe injury to the maternal bladder has been reported sporadically. Previously reported cases have been diagnosed under a variety of conditions, commonly at the time of repeat Cesarean delivery. A case of maternal bladder rupture diagnosed following forceps-assisted vaginal delivery after Cesarean is presented. Severe bradycardia developed suddenly in the second stage of labor. Rupture of the uterine scar was diagnosed after sudden onset of severe lower abdominal pain with delivery of the placenta. At laparotomy, extensive injury to the bladder was found and successful repair of both injuries was performed. A review of previously reported similar cases with their mechanism of injury and presentation is presented. Serious maternal bladder injury at the time of uterine rupture remains a risk of attempted vaginal delivery after prior Cesarean section. J. Matern.-Fetal Med. 2000;9:362–365. © 2000 Wiley-Liss, Inc.</p>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"362-365"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<362::AID-MFM1009>3.0.CO;2-T","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77166351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second trimester low-lying placenta and in-vitro fertilization? Exclude vasa previa","authors":"Yinka Oyelese,&nbsp;Catherine Spong,&nbsp;Miguel A. Fernandez,&nbsp;Rodney A. McLaren","doi":"10.1002/1520-6661(200011/12)9:6<370::AID-MFM1011>3.0.CO;2-E","DOIUrl":"10.1002/1520-6661(200011/12)9:6<370::AID-MFM1011>3.0.CO;2-E","url":null,"abstract":"<p>We report the prenatal diagnosis of vasa previa using transvaginal sonography and color Doppler. This case supports the previously reported association of vasa previa with second trimester low-lying placentas and in-vitro fertilization. Sonographic examination for vasa previa should be considered in pregnancies with low-lying placentas and those resulting from in-vitro fertilization. J. Matern.-Fetal Med. 2000;9:370–372. © 2000 Wiley-Liss, Inc.</p>","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"9 6","pages":"370-372"},"PeriodicalIF":0.0,"publicationDate":"2001-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1520-6661(200011/12)9:6<370::AID-MFM1011>3.0.CO;2-E","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79001754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in platelet count predicts eventual maternal outcome with syndrome of hemolysis, elevated liver enzymes and low platelet count.","authors":"B. K. Rinehart, D. Terrone, W. May, E. Magann, C. Isler, J. Martin","doi":"10.1080/714052712","DOIUrl":"https://doi.org/10.1080/714052712","url":null,"abstract":"Objective : To profile the rates of change for platelets and lactate dehydrogenase (LDH) in patients with the syndrome of hemolysis, elevated liver enzymes and low platelet count (HELLP) to reflect and possibly predict disease severity. Methods : Serial determinations of the platelet count and serum LDH were analyzed retrospectively for 545 patients with HELLP syndrome and 94 severely pre-eclamptic patients. A repeated measures (mixed model) analysis of variance (ANOVA) was utilized to estimate the rates of change for LDH and platelets in each group. Results : Patients who developed class 1 or 2 HELLP syndrome exhibited a rapid deterioration in platelet count of 45-50 000/ w l per day compared to 30 000/ w l per day for class 3 and non-HELLP severe pre-eclampsia. For LDH, values increased at a rate of approximately 1400 IU/l per day, 600 IU/l per day, 300 IU/l per day and 200 IU/l per day for patients with classes 1, 2 and 3 and for non-HELLP severe pre-eclampsia, respectively. Conclusion : The ra...","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"60 1","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2001-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78792847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful pregnancy outcome with cardiac and severe restrictive lung disease requiring mechanical ventilation: a case report and literature review.","authors":"C. S. Pope, T. Boley","doi":"10.1080/714052706","DOIUrl":"https://doi.org/10.1080/714052706","url":null,"abstract":"The prognosis for pulmonary hypertension as a single entity is poor, but when it is superimposed on the physiological changes of pregnancy, it produces a lethal condition, with maternal mortality rates greater than 50%. We present a successfully managed case followed by a review and discussion of the available literature on this subject. A 24-year-old woman, a primigravida, was mechanically ventilated for severe restrictive lung disease. Her pregnancy required close surveillance of her labile cardiopulmonary status as well as fetal well-being. Her delivery was scheduled for induction at 34 weeks' gestation, but she required an emergency Cesarean section, which was productive of a healthy infant. Her recovery was complicated by recurrent fever. There is limited literature on restrictive lung disease and pulmonary hypertension with regards to their management during pregnancy. Nevertheless, successful pregnancy outcomes may result with careful multidisciplinary management.","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"8 1","pages":"64-67"},"PeriodicalIF":0.0,"publicationDate":"2001-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89519542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The fetal superior cerebellar vermian width in normal, growth-restricted and macrosomic fetuses.","authors":"I. Goldstein, A. Tamir, E. Reece","doi":"10.1080/714052711","DOIUrl":"https://doi.org/10.1080/714052711","url":null,"abstract":"Objectives : To obtain dimensions of the fetal superior cerebellar vermian width as a basis for further studies and for comparisons with deviation in growth. Study design : The study group included 266 normal pregnant women from 20 to 37 weeks of gestation. Several biometric measurements were obtained throughout pregnancy, including the fetal superior cerebellar vermian width. Forty-three growth-restricted and 30 macrosomic fetuses were included in this study. Results : A linear growth function was observed between the superior cerebellar vermian width and gestational age (GA) ( R = 0.859; p < 0.00001; y = -4.033 + 0.416 2 GA), transverse cerebellar diameter (TCD) ( R = 0.870; p < 0.00001; y = 0.404 + 0.223 2 TCD), biparietal diameter (BPD) ( R = 0.823; p < 0.00001; y = -3.086 + 0.155 2 BPD), head circumference (HC) ( R = 0.82; p < 0.00001; y = -3.21 + 0.434 2 HC), femoral length (FL) ( R = 0.843; p < 0.00001; y = -1.75 + 0.184 2 FL) and humeral length (HL) ( R = 0.824; p < 0.00001; y = -2....","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"31 1","pages":"23-27"},"PeriodicalIF":0.0,"publicationDate":"2001-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78888257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy outcome in Hispanic patients with unexplained positive triple marker screening for Down syndrome.","authors":"C. Naylor, M. Porto, B. Cohen, T. Garite","doi":"10.1080/714052710","DOIUrl":"https://doi.org/10.1080/714052710","url":null,"abstract":"Objective : The objective of this study was to compare pregnancy outcomes in Hispanic patients with a positive serum triple marker screen for Down syndrome and normal fetal karyotype with Hispanic women who had a negative triple marker screen. Methods : This prospective investigation involved Hispanic gravidas who underwent maternal serum screening. A power analysis was performed to determine the sample size. Fifty women with false-positive screens for Down syndrome were matched with a control group of 100 women with a negative screen. Adverse pregnancy outcomes were compared between the two groups. Results : An adverse pregnancy outcome occurred in 14% of the study group and in 13% of controls. There were no statistically significant differences between the two groups in the incidence of preterm labor ( p > 0.5), pre-eclampsia ( p > 0.1), intrauterine growth restriction ( p > 0.5), or fetal demise ( p > 0.5). Conclusion : Hispanic patients with unexplained positive triple marker screen for Down syndrome ...","PeriodicalId":79464,"journal":{"name":"The Journal of maternal-fetal medicine","volume":"63 1","pages":"20-22"},"PeriodicalIF":0.0,"publicationDate":"2001-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90351340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}