{"title":"The clinical context: a tool for fine-tuning objective histologic diagnosis of cutaneous pigmented lesions.","authors":"T H McCalmont","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dermatopathology is a science founded in clinicopathologic correlation. This essay attempts to point out some of the clinical features that can be matched with pathologic counterparts to enable more accurate diagnosis of both benign and malignant pigmented lesions of the skin. No shred of information, be it descriptive or demographic, should be overlooked in a Holmesian quest for the perfect diagnosis.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"143-80"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pigmented lesion pathology: the specimen and its report. A personal and probably biased approach.","authors":"R W Sagebiel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author outlines general principles and pitfalls in the pathologic interpretation of pigmented skin lesions, then focuses on issues related specifically to gross tissue specimens and to the histologic report. He concludes that definitive therapy for melanoma should not be based on partial biopsies, that frozen sections are not indicated, and that the pathologist should report all of the relevant histologic attributes whenever possible.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"281-98"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Desmoplastic neurotropic malignant melanoma.","authors":"J A Carlson, B M Egbert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Desmoplastic neurotropic malignant melanoma is a rare spindle cell variant of malignant melanoma. This chapter reviews its clinical presentation; histologic, immunohistochemical, and ultrastructural features; differential diagnosis; and critical therapeutic issues.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"339-57"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Well-differentiated serous neoplasms of the ovary.","authors":"T A Longacre, R L Kempson, M R Hendrickson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serous neoplasms of the ovary, which constitute the largest subgroup of the surface epithelial tumors, cluster into three distinctly clinicopathologic groups: benign neoplasms, which are architecturally noncomplex, confined to the ovary, and composed of cytologically bland cells; carcinomatous neoplasms, which have spread beyond the ovary and are cytologically malignant; and an intermediate group, which raises serious problems in taxonomy, differential diagnosis, and prognosis. This chapter focuses on differential diagnosis, emphasizing the authors' experience as well as reports from other investigators.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"255-306"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review of sudden infant death syndrome.","authors":"C Rambaud, P Walpita, H F Krous","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This chapter defines sudden infant death syndrome (SIDS) and provides a brief review of the history, current knowledge, pathology, and possible mechanisms of death. The authors conclude with considerations of other selected causes of sudden, unexpected infant death.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathology of pediatric AIDS.","authors":"V M Anderson, E Zevallos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>AIDS in children most often results from the transmission of HIV from an infected mother to her newborn infant. The number of HIV-infected infants and children is increasing. This chapter addresses the natural history of the disease, opportunistic and other infections in afflicted patients, lymphoproliferative syndromes, cardiovascular disease, HIV nephropathy, gastrointestinal pathology, neuropathologic findings, and neoplasms. The authors emphasize that the autopsy is a powerful research tool that allows systematic and thorough review of AIDS cases.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"81-101"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric liver tumors.","authors":"R A Williams, L D Ferrell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The information in this chapter is a resource for the pathologist faced with a pediatric liver tumor. Each tumor is characterized concisely and appropriate references are provided for more detailed study. Examples of tumors are presented from the files of Children's Hospital-Oakland and from the University of California Medical Center.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"23-42"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laboratory diagnosis of perinatal infections.","authors":"D Scharnhorst, S Kassel, A Siongco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The application of new technology to the diagnosis of infectious disease in neonates has markedly increased the potential for early clinical intervention. Although far from perfect, the new tests have increased knowledge of the nature of these diseases and give physicians the opportunity to apply current treatments more effectively as well as to develop new modes of therapy for this important class of diseases.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"117-36"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital brain tumors.","authors":"J M Raisanen, R L Davis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The most common brain tumor that was present or produced symptoms at birth was teratoma. In this series of congenital tumors, teratomas occurred over 5 times more frequently than the second most common type, astrocytoma. They were often immature because of primitive neural elements and, rarely, a component of mixed malignant germ cell tumors. Incidence between sexes was nearly identical among histologic types that were reported at least 10 times, except for choroid plexus papilloma, which exhibited a male predominance. Four of five meningiomas occurred in males and 4 of 5 sarcomas in females. The predilection of neonatal brain tumors for supratentorial locations was also observed in this series of tumors present at birth. Teratomas occurred above the tentorium almost exclusively and all craniopharyngiomas and 14 of 16 choroid plexus tumors occurred supratentorially. At birth, large head or tense fontanel was a presenting sign in at least 55% of patients. Neurologic symptoms as initial symptoms were comparatively rare. Teratomas and craniopharyngiomas are tumors believed to arise because of developmental defects and these were the tumors that most often occurred with other anomalies. Anomalies were usually located in the head, with cleft lip or palate being most frequent. Prognosis for patients with brain tumors at birth was very poor, usually because of the massive size of the tumor. However, if small and favorably located, tumors were resected successfully. The most favorable outcomes were with choroid plexus tumors where aggressive treatment led to disease-free survival.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"103-16"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Well-differentiated mucinous neoplasms of the ovary.","authors":"M R Hendrickson, R L Kempson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Well-differentiated mucinous ovarian neoplasms fall into several more or less distinct morphologic groups. One of the major problems, however, is correlation of morphologic groups with clinical outcome. The authors analyze this problem in regard to the major morphologic distinctions, morphologic syndromes, and taxonomic quandaries, concluding with an overview of miscellaneous significantly related topics.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"307-34"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}