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Update on chronic hepatitis: changing views on nomenclature and outcome. 慢性肝炎的最新进展:对命名法和结果的看法不断变化。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
S Govindarajan
{"title":"Update on chronic hepatitis: changing views on nomenclature and outcome.","authors":"S Govindarajan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As old terminologies begin to fail, the author says that the world of hepatopathology is ready to reassess the classification of chronic hepatitis. This chapter reviews the current status of diagnostic features and terminologies for chronic B, C, and D hepatitis and discusses recent recommendations for future directions in nomenclature.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 1","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20348587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New approaches to treatment of chronic viral hepatitis. 治疗慢性病毒性肝炎的新途径。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
C C Holland, T L Wright
{"title":"New approaches to treatment of chronic viral hepatitis.","authors":"C C Holland,&nbsp;T L Wright","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite rapid progress in knowledge of the biology of hepatitis viruses, the ability to treat chronic infection is limited. In fact, interferon-alpha 2b is the only FDA-approved therapy for chronic HBV and chronic HCV. The authors report on the interferons and evolving therapies for chronic viral hepatitis and conclude with a discussion of liver transplantation.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 1","pages":"23-40"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20348589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenchymal tumors of the liver. Diagnostic problems for the surgical pathologist. 肝脏间充质瘤。外科病理学家的诊断问题。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
J R Craig
{"title":"Mesenchymal tumors of the liver. Diagnostic problems for the surgical pathologist.","authors":"J R Craig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although some mesenchymal lesions include readily diagnosable entities, some patients have difficult presentations and unusual radiographic results. This review of mesenchymal tumors covers hemangioma, infantile hemangioendothelioma, angiomyolipoma, angiosarcoma, epitheloid hemangioendothelioma, fibroma, malignant fibrous histiocytoma, inflammatory pseudotumor, mesenchymal hamartoma, embryonal sarcoma, and sarcomatoid hepatocellular carcinoma.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 1","pages":"141-60"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The many faces of completely regressed malignant melanoma. 完全退化的恶性黑色素瘤的许多面。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
R J Barr
{"title":"The many faces of completely regressed malignant melanoma.","authors":"R J Barr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The prognostic significance of clinical and histologic regression of malignant melanoma is highly controversial. Although small foci of regression in evolving malignant melanomas seem to have little or no effect on morbidity and mortality, extensive regression in larger, fully evolved lesions may be associated with poor prognosis. This chapter emphasizes the histologic features of regression and the patterns that are responsible for diagnostic pitfalls.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"359-70"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biopsy techniques for pigmented lesions of the skin. 皮肤色素病变的活检技术。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
J K Geisse
{"title":"Biopsy techniques for pigmented lesions of the skin.","authors":"J K Geisse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Proper biopsy techniques for pigmented skin lesions are critical to early detection and treatment of malignant melanoma. Complete surgical excision allows evaluation of size, symmetry, circumscription, and maturation, whereas partial biopsies may result in misinterpretation because of sampling error or inadequate architectural detail. The author briefly reviews standard techniques for excisional biopsy and addresses special clinical scenarios in which incisional or partial biopsies may be necessary.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"181-93"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simulants of malignant melanoma: a rogue's gallery of melanocytic and nonmelanocytic imposters. 恶性黑色素瘤的模拟物:黑素细胞和非黑素细胞骗子的流氓画廊。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
P E LeBoit
{"title":"Simulants of malignant melanoma: a rogue's gallery of melanocytic and nonmelanocytic imposters.","authors":"P E LeBoit","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Although overdiagnosis of malignant melanoma involves no potential loss of life, it affects the patient profoundly and therefore should be addressed conscientiously. This review of both benign and malignant, melanocytic and nonmelanocytic simulants of malignant melanoma emphasizes the pitfalls and repercussions of misdiagnosis. For more accurate differentiation, simulants are classified first as superficial (intraepidermal) or deep (dermal), then as melanocytic or nonmelanocytic.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"195-258"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification of melanoma in adults and children. 成人和儿童黑色素瘤的分类。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
L A Perkocha
{"title":"Classification of melanoma in adults and children.","authors":"L A Perkocha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After a brief history of the classification of melanoma in adults, this chapter describes the major features of the classic histogenetic types as well as of uncommon variants. Particular attention is paid to the meaning of controversial terms such as \"minimal deviation\" and \"borderline.\" Specific problems associated with the classification of melanoma in children are also addressed, along with interpretation of atypical lesions resembling Spitz nevi.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"299-338"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunohistochemistry in the diagnosis of melanocytic neoplasms. 免疫组织化学在黑色素细胞肿瘤诊断中的应用。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
B R Smoller
{"title":"Immunohistochemistry in the diagnosis of melanocytic neoplasms.","authors":"B R Smoller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>At present the primary role of immunohistochemistry is to define an immunophenotypic profile that is characteristic of melanocytes but rare in other cell types. Its future role may include prediction of how a melanocytic neoplasm will behave. This chapter outlines a strategy for the use of immunohistochemical procedures to identify a neoplasm as melanocytic and discusses the antibodies that are relatively melanoma-specific.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 2","pages":"371-83"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benign hepatocellular tumors and tumor-like lesions. 良性肝细胞肿瘤及肿瘤样病变。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
L M Petrovic
{"title":"Benign hepatocellular tumors and tumor-like lesions.","authors":"L M Petrovic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Benign tumors of the liver are uncommon, and their diagnosis has never been easy. This chapter highlights the most useful criteria for the diagnosis of benign tumors and tumor-like lesions and emphasizes histologic and immunohistochemical approaches that are helpful in differentiating these conditions.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 1","pages":"119-39"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liver disease in the immunocompromised patient. 免疫功能低下患者的肝脏疾病。
Pathology (Philadelphia, Pa.) Pub Date : 1994-01-01
M E Robert
{"title":"Liver disease in the immunocompromised patient.","authors":"M E Robert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This chapter reviews the most common diseases of the liver that are associated immunodeficiencies resulting from AIDS, chemotherapy and radiation, and bone marrow and solid organ transplantation. Conditions described include liver disease, infection, venoocclusive disease, graft versus host disease, and others.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"3 1","pages":"185-206"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20349151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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