{"title":"Serous and mesothelial proliferations of the extraovarian peritoneum and pelvic lymph nodes.","authors":"A N Walker, S E Mills","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With rare exceptions, serous proliferations of the peritoneum are limited to women, whereas proliferations of mesothelial differentiation arise predominantly in men. The authors focus on the various types of serous and mesothelial proliferations of the peritoneum and pelvic lymph nodes. Discussion of each type focuses on clinical and morphologic features, histogenesis, differential diagnosis, and clinical outcome.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"411-39"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Miscellaneous types of surface epithelial neoplasms. The well-differentiated end of the morphologic spectrum of endometrioid, clear-cell, and Brenner tumors and mixed epithelioid tumors of low malignant potential of müllerian type.","authors":"R L Kempson, M R Hendrickson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Benign ovarian neoplasms with endometrioid or clear-cell differentiation are rare, but benign Brenner tumors are not unusual. A subgroup of endometrioid, clear-cell, and Brenner neoplasms, characterized by morphologic features intermediate between benign and malignant, has been labelled by various investigators as borderline, of low malignant potential (LMP), or proliferating. This chapter reviews the definition of each of these cell types, evaluates the significance of the LMP category, and concludes with a discussion of well-differentiated ovarian neoplasms with mixed differentiation of the müllerian type.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"335-65"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential diagnosis of surface epithelial carcinomas.","authors":"R H Young","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Usually the interpretation of surface epithelial carcinomas is relatively straightforward, but diverse problems in differential diagnosis occasionally arise, often with major implications for management. The author examines three types of problems in the various categories of ovarian carcinoma: (1) confusion with other surface carcinomas; (2) simulation of surface epithelial carcinomas by tumors in other categories; and (3) simulation of tumors in other categories by surface epithelial carcinomas.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"441-76"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumors of the neuroblastoma group.","authors":"H Shimada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The basic histologic changes associated with the maturational sequences of neuroblastoma tumors are reviewed. The author describes a histopathologic classification system developed for distinguishing favorable and unfavorable prognoses, based on the combination of tumor morphology and patient's age at diagnosis. Also discussed are the results of recent analyses of the biologically significant relationship between histologic findings and molecular markers, such as amplification of the N-myc oncogene and expression of the nerve growth factor receptor gene. Clinical trials involving neuroblastoma tumors are briefly reviewed.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"2 1","pages":"43-59"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinicopathology of malignant surface epithelial neoplasms of the ovary.","authors":"M R Hendrickson, T A Longacre, R L Kempson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Because clinical outcome in patients with malignant surface epithelial neoplasms (M-SENs) of the ovary is highly varied, stratification of patients into favorable and unfavorable prognostic groups is an important clinicopathologic function. This chapter analyzes the various prognostic factors, with an emphasis on M-SENs of grades II and III.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"367-410"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Principles of surgical management of ovarian carcinomas.","authors":"K A O'Hanlan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nearly 80% of the approximately 20,000 women who develop ovarian carcinoma each year in the United States are diagnosed at stages II, III, or IV. The main goals of surgery in these patients are confirmation of diagnosis, accurate staging of the tumor, and reduction of tumor bulk. Among the topics discussed are intraoperative management, differential diagnosis by frozen section, pediatric tumors, ovarian carcinoma during pregnancy, second-look operations, and laparoscopic surgery.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"477-89"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20347756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Classification of surface epithelial neoplasms of the ovary.","authors":"M R Hendrickson, T A Longacre","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Surface epithelial neoplasms of the ovary, which represent about two-thirds of all primary ovarian neoplasms and almost 90% of all malignant ovarian tumors, are a variegated and heterogeneous collection of proliferations. The standard classification of ovarian neoplasms is the system developed by the World Health Organization in 1973; various studies, however, have found that observer variability for problematic cases is substantial. Prognosis and quality assurance make this variability a major concern. The authors examine the reasons behind this variability, the theories behind classification systems in general, problems of taxonomy, and the significance of confidence intervals. Appendices develop more fully the authors' approach to problems of classification and interobserver agreement, with notes on specific differentiated types of ovarian neoplasms.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 2","pages":"189-254"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In situ proliferative epithelial lesions of the breast.","authors":"O W Kamel, R L Kempson, M R Hendrickson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Considerable progress has been made over the last several years toward understanding the significance of noninvasive epithelial changes in the breast. This progress, in essence, is the result of categorizing in situ alterations according to their clinical significance, or more specifically, according to the risk that such lesions carry to the patient for development of a subsequent invasive carcinoma. This article summarizes the histopathological criteria that are currently used to define morphologic categories and, perhaps more importantly, it reviews the clinical implications of the diagnoses that result from this categorization.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 1","pages":"65-102"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Steroid receptors in surgical pathology. With special reference to small mammographically detected breast lesions.","authors":"J C Ross, S Binder, M C Rounsaville, K Lewin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The cellular receptors for estrogen, progesterone, and other steroid hormones appear in the cytosol fraction of homogenated specimens of hormonal target tissues. These receptors have traditionally been detected and quantitated by biochemical techniques that involve binding tritium-labelled marker steroids to the receptor proteins. An important recent development has been the creation of various monoclonal antibody reagents that specifically recognize antigenic determinants on receptor molecules.</p>","PeriodicalId":79452,"journal":{"name":"Pathology (Philadelphia, Pa.)","volume":"1 1","pages":"103-35"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}