Romanian journal of physiology : physiological sciences最新文献_第7页

Activity of Na+/K+-ATPase and of Ca++-ATPase under the action of adenosine triphosphate in experimental myocardial hypertrophy. 三磷酸腺苷作用下心肌肥大Na+/K+- atp酶和Ca++- atp酶活性的变化。

Romanian journal of physiology : physiological sciences Pub Date : 1998-07-01

C Moisin, N Balta, V Filcescu, I F Dumitriu, G Stoian, G Petec

{"title":"Activity of Na+/K+-ATPase and of Ca++-ATPase under the action of adenosine triphosphate in experimental myocardial hypertrophy.","authors":"C Moisin, N Balta, V Filcescu, I F Dumitriu, G Stoian, G Petec","doi":"","DOIUrl":"","url":null,"abstract":"This paper presents the results of our research on the mechanisms involved in the modifications occurring in the activity of ionic pumps (Na+/K+-ATPase and Ca++-ATPase) at the level of the sarcolemma, the sarcoplasmic reticulum and mitochondrial membrane of the myocardial cell in experimental myocardial hypertrophy induced by isoproterenol. We also studied the effects of concomitant administration of adenosine triphosphate. Thus, we found the activity of the sarcolemmal Ca++-ATPase intensely increased under the action of isoproterenol, while Ca++-ATPase activity in the sarcoplasmic reticulum decreased significantly. At the same time, the Na+/K+-ATPase activity decreased both in the sarcolemma and in the sarcoplasmic reticulum. Administration of adenosine triphosphate induces opposite effects, of lower intensity, upon the activity of the two ATPase, that tend to offset the the effects of isoproterenol. This was found in the group of rats given concomitantly both isoproterenol and adenosine triphosphate. A better understanding of the processes involved in those modifications of membrane ATPase activity allows us to consider their different behaviour to isoproterenol and adenosine triphosphate as the expression of intrinsic mechanisms by means of which the myocardial cell intervenes in maintaining a physiological concentration of calcium ions (Ca++) that is necessary both in order to avoid a failure of the contractile apparatus and in order to preserve the mitochondria role of ATP supplier. Our results demonstrate the antiadrenergic action of adenosine triphosphate that attenuates isoproterenol effects on cardiac myocytes.","PeriodicalId":79373,"journal":{"name":"Romanian journal of physiology : physiological sciences","volume":"35 3-4","pages":"303-11"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21889818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of molecular biology in the progress of medical science. 分子生物学在医学进步中的作用。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

I Haulică, V Rusu, W Bild

引用次数: 0

EEG differences between the opioid and adrenergic psyhoneuroendocrine rat types. 阿片类和肾上腺素能性精神神经内分泌大鼠脑电图差异。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

A Cristea, M Moldovan, A M Munteanu, D P Popa, S Nergreş, L Zăgrean

{"title":"EEG differences between the opioid and adrenergic psyhoneuroendocrine rat types.","authors":"A Cristea, M Moldovan, A M Munteanu, D P Popa, S Nergreş, L Zăgrean","doi":"","DOIUrl":"","url":null,"abstract":"Our work is based on the hypothesis of the existence of an opioid psychoneuroendocrine type named \"O\" type (Cristea, 1993), opposed to the well known adrenergic \"A\" type described by Roseman and Friedman in 1980. In the present study we tested the differences between the background EEG activity (BEA) of the \"O\" and \"A\" rat types during restrained wakefulness and anesthesia with Ether and chloral hydrate (CHL). The differentiation of the psyhoneuroendocrine rat types was made using the level of painful sensitivity. 13 hypersensitive \"A\" and 14 hyposensitive \"O\" rats were selected from a 91 adult (140 g) male Wistar population using the distribution of the tail retraction time (TRT) during a tail-flick test. The epidural EEG activity, was quantified within the 1-30 Hz band by six numerical parameters: root mean square (RMS), mean spectral frequency (MSF), spectral edge frequency at 95% (SEF95) and the relative spectral power (RSP) within the Theta (4.5-7.5 Hz), Alpha (7.5-12 Hz) and Beta (12.5-30 Hz) bands. The quantification method used was able to detect statistically significant differences between the two psyhoneuroendocrine rat types during consciousness and light ether anesthesia but failed to show any differences during the deep CHL anesthesia. The particularities were shown to be topographically related with the fronto-parietal regions were \"O\" type showed a higher SEF95 during the awake restrained state. The pain sensitive \"A\" type showed a significant intrahemispheric theta RSP asymmetry both during consciousness and ether anesthesia while no such theta gradient could be shown for the \"O\" type. The differences between the \"A\" and \"O\" types are enhanced under light Ether anesthesia to which the \"A\" type is more resistant. The EEG complementarity between the \"A\" and \"O\" types is discussed.","PeriodicalId":79373,"journal":{"name":"Romanian journal of physiology : physiological sciences","volume":"35 1-2","pages":"153-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21833355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of morphofunctional lesions in the cervical region of patients with gall-bladder dyskinesia. 胆囊运动障碍患者宫颈区形态功能病变的发生率。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

M Uluitu, C Teleianu, N Stoicescu

{"title":"Incidence of morphofunctional lesions in the cervical region of patients with gall-bladder dyskinesia.","authors":"M Uluitu, C Teleianu, N Stoicescu","doi":"","DOIUrl":"","url":null,"abstract":"During research performed in humans of both sexes, aged 17-30, suffering from disorders of gall-bladder kinetics, we found a constant association between this disorder and a cervical syndrome with occipital cephalea, spasmophilia, pre-molar and molar dental decay, even to edentation. We believe the mechanism inducing those disorders originates in the malabsorption of vitamin D2, caused by the absence of biliary salts in the intestine. Our findings could be of interest for the therapeutic management of such cases. In conclusion, we describe a new clinical framework establishing a pathological pattern that is functionally and morphologically coherent. The pattern includes the motor-biliary condition that induces disorders in the mechanism of calcium metabolism control. It also includes major neuromuscle hyperexcitability in the pre-vertebral region associated with the biped posture. Functional and morphological lesions in the cervical region of the spine, with Arnold-type manifestations and spasmophilia prevail in the final clinical picture. This picture is very early associated with multiple dental caries that may progress to edentation. The clinical picture appears as a coherent pattern, from a clinical, morpho-functional and pathogenic perspective.","PeriodicalId":79373,"journal":{"name":"Romanian journal of physiology : physiological sciences","volume":"35 1-2","pages":"61-6"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21834257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cloning and gene expression of alpha-3/4-fucosyltransferase lewis in the chimpanzee] . 黑猩猩α -3/4-聚焦转移酶lewis的克隆与基因表达

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

M Costache, D Iordăchescu, R Oriol, R Mollicone

引用次数: 0

Reactivity of HeLa tumoral cells under the in vitro action of some aromatic compounds from the phytomass. 植物提取物中芳香族化合物体外作用下HeLa肿瘤细胞的反应性。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

P Rotinberg, V Nuţă, S Kelemen, D Petraşincu, H Rotinberg

引用次数: 0

The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. 锂-亚麻酸在体外逆转LPBM5 MuLV诱导的造血祖细胞抑制中的作用。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

O R Oakley, N K Hughes, N J Birch, M L Winther, D F Horrobin, V S Gallicchio

{"title":"The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro.","authors":"O R Oakley, N K Hughes, N J Birch, M L Winther, D F Horrobin, V S Gallicchio","doi":"","DOIUrl":"","url":null,"abstract":"Lithium gamma linolenic acid (Li-GLA), was evaluated for its possible role as an antiviral agent. Li-GLA 15 micrograms ml-1 was administered to both normal and LP-BM5 MuLV retroviral infected murine bone marrow cultures. After 2 weeks of treatment, numbers of progenitors being produced by infected/treated cultures were reduced to some 10% that of normal cultures. In the remaining 4 weeks, numbers of CFU-GM and BFU-E hematopoietic progenitors returned within normal range. The efficacy of Li-GLA in relieving retroviral hematopoietic bone marrow suppression correlates to a reduction in interleukin-4 (IL-4) secretion, normally elevated in association with LP-BMP5 infection. These data indicate that this reduction in bone marrow suppression of LP-BMP5 infected cells may be due to a killing of infected cells by the Li-GLA, rather than stimulating hematopoiesis as with other lithium compounds. To conclude this may indicate the possible dual effect of administration of LiGLA to virally infected individuals in reducing viral titre and to lower the toxicities associated with long term drug therapy.","PeriodicalId":79373,"journal":{"name":"Romanian journal of physiology : physiological sciences","volume":"35 1-2","pages":"13-24"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21832984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diurnal behaviour of some salivary parameters in patients with diabetes mellitus (flow rate, pH, thiocianat, LDH activity)--note II. 糖尿病患者一些唾液参数的日行为(流速、pH值、硫噻嘧啶、LDH活性)——注2。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

S Ionescu, D Bădiţă, M Artino, M Dragomir, E Huidovici, V Niţă, E Chiţoi

{"title":"Diurnal behaviour of some salivary parameters in patients with diabetes mellitus (flow rate, pH, thiocianat, LDH activity)--note II.","authors":"S Ionescu, D Bădiţă, M Artino, M Dragomir, E Huidovici, V Niţă, E Chiţoi","doi":"","DOIUrl":"","url":null,"abstract":"The study was performed on 31 diabetic patients of both sexes, divided in 2 groups: group I--17 patients with insulin-dependent diabetes (IDDM) and group II--14 patients with noninsulin-dependent diabetes (NIDDM) and compared with a control group of 16 non-diabetic subjects. Mixed saliva was sampled without stimulation during 2 periods of the day: 07:30-08:00 before breakfast and 17:30-18:00 before dinner. We determined: salivary flow rate, pH with Merck indicator and, after homogenization, the thiocianat with the FeCl3 method and LDH activity (the Norbert method adapted in our laboratory for saliva). Our study showed the same diurnal changes in flow rate and salivary pH in both diabetic and control groups: minimal values in the morning and maximal ones in the afternoon. In non-smoking diabetic patients the salivary thiocianat had maximal values in the morning and minimal ones in the afternoon; similar behaviour, but less obvious was observed in smoking diabetic patients and in the control group regardless of the smoking habit. LDH activity showed unsignificant diurnal variations in the diabetic patients. In the control group we found a significant decrease of LDH activity in the afternoon. The discussion is about the implication of these salivary parameters in the pathology of oral cavity: gingivitis, periodontitis and caries in diabetic patients.","PeriodicalId":79373,"journal":{"name":"Romanian journal of physiology : physiological sciences","volume":"35 1-2","pages":"85-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21834261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Human abh and lewis antigens. Original report]. 人类abh和lewis抗原。原始报告)。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

M Costache, A Dinischiotu, D Iordăchescu

引用次数: 0

Effects of heavy and deuterium-depleted water on vascular reactivity. 重水和贫氘水对血管反应性的影响。

Romanian journal of physiology : physiological sciences Pub Date : 1998-01-01

I Haulică, M Peculea, I Stefănescu, G Tiţescu, M Todiraş, W Bild

引用次数: 0