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Clinicopathological study on craniopharyngioma with sebaceous differentiation. 皮脂腺分化型颅咽管瘤的临床病理研究。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
S Tsunoda, T Sakaki, A Tsutsumi, T Eguchi, T Takeshima, T Morimoto, H Hashimoto, R Kiriishi, M Nakamura, T Tsuzuki
{"title":"Clinicopathological study on craniopharyngioma with sebaceous differentiation.","authors":"S Tsunoda,&nbsp;T Sakaki,&nbsp;A Tsutsumi,&nbsp;T Eguchi,&nbsp;T Takeshima,&nbsp;T Morimoto,&nbsp;H Hashimoto,&nbsp;R Kiriishi,&nbsp;M Nakamura,&nbsp;T Tsuzuki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We presented 2 cases of craniopharyngioma, which showed sebaceous differentiation. Both cases shared the following features: 1) neuroradiological detection of a cystic tumor accompanied by calcification, 2) clear yellowish fluid detected in the cyst during surgery, 3) histological rating as an adamantinomatous type, 4) the presence of a nest-like distribution of multivacuolated cells in the innermost layer of the cyst.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19209761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lectins: reliable differentiation markers in human oligodendrogliomas. 凝集素:人少突胶质细胞瘤的可靠分化标志物。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
J Figols, J Cervós-Navarro, F F Cruz-Sánchez
{"title":"Lectins: reliable differentiation markers in human oligodendrogliomas.","authors":"J Figols,&nbsp;J Cervós-Navarro,&nbsp;F F Cruz-Sánchez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ninety tumours classified as well-differentiated oligodendrogliomas (43 cases) and anaplastic oligodendrogliomas (47 cases) were studied with glial fibrillary acidic protein (GFAP) and bound with different lectins including: peanut agglutinin (PNA), concanavalin A (Con A), wheat germ agglutinin (WGA) and Ricinus communis agglutinin (RCA-1). PNA has shown high affinity to cellular membranes of well-differentiated oligodendrogliomas. The affinity decreases with the cellular differentiation to astrocytic lines and is lost in anaplastic oligodendrogliomas. Con A labelling is restricted to anaplastic oligodendroglioma cells and to reactive astrocytes showing a predominant somatic (cytoplasmatic) pattern of staining. Our findings showed that a combined search with GFAP and lectins may allow an accurate grading of oligodendrogliomas.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19209754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malignant astrocytoma with extracranial metastases: a case report. 恶性星形细胞瘤伴颅外转移1例。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
K Kurisu, T Uozumi, K Kiya, T Yano, H Ogasawara, K Sugiyama, K Harada, T Nishizaka, K Inai
{"title":"Malignant astrocytoma with extracranial metastases: a case report.","authors":"K Kurisu,&nbsp;T Uozumi,&nbsp;K Kiya,&nbsp;T Yano,&nbsp;H Ogasawara,&nbsp;K Sugiyama,&nbsp;K Harada,&nbsp;T Nishizaka,&nbsp;K Inai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 41-year-old man was referred to this hospital after being diagnosed as suffering from malignant astrocytoma. In spite of two operations and subsequent chemoradiation therapy, the patient died 20 months after the onset of disease. At autopsy, the authors found skin invasion of tumor at left temporal region, softening of the brain and subarachnoid hemorrhage at the base of the brain. Yellowish-white bulging lesions were found at the bottom of left lung, diaphragm and parietal pleura. Histologically, primary lesion showed features of anaplastic malignant astrocytoma. Subarachnoid dissemination was noted at the base of the brain and in the spinal canal. Invasion into the vessels were observed both at the primary site and at the base of the brain. Glial fibrillary acidic protein positive spindle-shaped tumor cells proliferation was seen in the metastatic lesions. This case was diagnosed as malignant astrocytoma with remote extracranial metastases.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaplastic astrocytoma in the cerebellopontine angle. 桥小脑角间变性星形细胞瘤。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
T Kawase, T Nakamura, T Kanno, Y Nakazato
{"title":"Anaplastic astrocytoma in the cerebellopontine angle.","authors":"T Kawase,&nbsp;T Nakamura,&nbsp;T Kanno,&nbsp;Y Nakazato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this paper we present a case of glioma which was located in the cerebellopontine angle. The patient, a 3-year-old male, experienced difficulty with gait for one month before admission. He was admitted to Toyota Memorial Hospital on February 2, 1991, suffering from severe headache and vomiting. Neurological examination upon admission revealed horizontal nystagmus and ataxia. MRI revealed a mass in the cerebellopontine angle. Craniotomy was performed on February 4, 1991, and a tumor was revealed in the cerebellopontine angle. The tumor was clearly demarcated and encapsulated; the cerebellum and brainstem were compressed without damage. Most of the tumor was removed. A histopathological summary of the tumor follows. The tumor appeared as exophytic lesions on the pons, extending into the cerebellopontine angle. Tumor cells contained small round nuclei and acidophilic cytoplasm. The oncocyte, which was growing endomorphically, revealed a short-cell projection, suggesting a tendency to penetrate blood vessels. Intercellular microcystic degeneration was observed clearly, with some parts of the oncocyte forming a myxoid matrix. Immunohistochemically, most of the tumor cells reacted positively to Vimentin, but negatively to S-100 protein and GFAP. Given the pathological information, the tumor was interpreted as anaplastic astrocytoma. Postoperative radiation therapy was performed, but the patient died four months later because the tumor had spread to the brainstem. In this paper we discuss the differential diagnosis of the cerebellopontine angle tumor and the appearance of anaplastic astrocytoma as exophytic lesions on the pons and the spread of the tumor into the cerebellopontine angle.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19209759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoradiographic analysis of (14C-methyl)-L-methionine uptake in transplanted rat brain tumors. 大鼠移植脑瘤中(14c -甲基)- l -蛋氨酸摄取的放射自显像分析。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
T Sasajima, K Mineura, N Kuwahara, M Kowada, M Murakami, K Uemura
{"title":"Autoradiographic analysis of (14C-methyl)-L-methionine uptake in transplanted rat brain tumors.","authors":"T Sasajima,&nbsp;K Mineura,&nbsp;N Kuwahara,&nbsp;M Kowada,&nbsp;M Murakami,&nbsp;K Uemura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To elucidate metabolic pathways of methionine in brain tumors, we studied autoradiographic images of (14C-methyl)-L-methionine (14C-Met) in transplanted rat brain tumors. 14C-Met accumulated in the tumor almost twice as much as in the gray matter 90 min after injection. The acid-insoluble fraction, which was bound to macromolecules, comprised 84% the total count of the accumulated tracers in the tumor. Analysis of 14C-Met tracer accumulation is informative for understanding amino acid metabolism in brain tumors.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ossifying cementicular fibroma of the orbitofrontal bone in a child: case report. 儿童眶额骨骨化性骨质纤维瘤1例报告。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
M Takaya, K Moritake, H Nagai, A Tsutsumi, T Yamasaki
{"title":"Ossifying cementicular fibroma of the orbitofrontal bone in a child: case report.","authors":"M Takaya,&nbsp;K Moritake,&nbsp;H Nagai,&nbsp;A Tsutsumi,&nbsp;T Yamasaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rare case of ossifying cementicular fibroma of the left orbitofrontal bone that developed in a 12-year-old boy is presented. A hard, painless mass that was incidentally noticed gradually enlarged over 2 years. Skull X-rays showed a well-demarcated lesion with mixed sclerotic and osteolytic radiolucent changes in the left orbitofrontal bone. Computed tomography revealed an expansile intradiploic multilocular mass that was separated by bony trabeculae. T1-weighted magnetic resonance imaging demonstrated a multi-cystic iso-intense mass with homogeneous contrast enhancement. Left external carotid angiograms revealed a vague tumor stain that was mainly fed by the middle meningeal artery. Systemic bone scintigrams revealed a single abnormal uptake in the lesion. The skull tumor was totally removed. Histological examination demonstrated two different characteristic findings that were composed of fibrous dysplasia and cementifying fibroma, although most of the tumor appeared to be a highly cementicular form of fibro-osseous lesion. The pathological diagnosis was a cementicular variant of fibrous dysplasia.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunohistochemical study of copper and zinc-superoxide dismutase (Cu, Zn-SOD) in meningiomas. 脑膜瘤中铜锌超氧化物歧化酶(Cu, Zn-SOD)的免疫组化研究。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
M Kurisaka, K Mori
{"title":"Immunohistochemical study of copper and zinc-superoxide dismutase (Cu, Zn-SOD) in meningiomas.","authors":"M Kurisaka,&nbsp;K Mori","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A localization of copper and zinc-superoxide dismutase (Cu, Zn-SOD) in meningiomas was examined with immunohistochemical technique. Meningiomas include five meningotheliomatous, five transitional, two fibroblastic, and one of each angioblastic, malignant and hemangiopericytic types. The Cu, Zn-SOD localized diffusely in the cytoplasm of tumor cells and in the endothelial cell of vessels and neutrophils, macrophages and red blood cells in the vessels or in the tumor tissue. The Cu, Zn-SOD content in meningiomas was markedly higher in angioblastic, malignant and hemangiopericytic than in meningotheliomatous, transitional and fibroblastic types.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Origin of craniopharyngioma: an electron microscopic study. 颅咽管瘤的起源:电子显微镜研究。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
N Kawano, H Oka, T Suwa, H Ito, K Yada, T Kameya, S Yagishita
{"title":"Origin of craniopharyngioma: an electron microscopic study.","authors":"N Kawano,&nbsp;H Oka,&nbsp;T Suwa,&nbsp;H Ito,&nbsp;K Yada,&nbsp;T Kameya,&nbsp;S Yagishita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To investigate the possibility that the two subtypes of craniopharyngioma, adamantinous type and squamous papillary type, are tumors arising from different origins, the authors conducted an electron microscopic study in 10 cases of craniopharyngioma. Light microscopic study revealed distinct differences between the two subtypes, but their ultrastructure was fundamentally similar. In this report, the authors propose an explanation of the origin of these subtypes to account for the findings.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medulloblastoma associated with malignant rhabdoid tumor of the kidney: case report. 肾髓母细胞瘤合并恶性横纹肌样瘤1例。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
K Watanabe, S Wakai, N Kumakura, A Kurosu, M Nagai, T Tsuchioka, T Fujiwara
{"title":"Medulloblastoma associated with malignant rhabdoid tumor of the kidney: case report.","authors":"K Watanabe,&nbsp;S Wakai,&nbsp;N Kumakura,&nbsp;A Kurosu,&nbsp;M Nagai,&nbsp;T Tsuchioka,&nbsp;T Fujiwara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report a case of 6-month-old boy with cerebellar medulloblastoma associated with malignant rhabdoid tumor of the kidney, presenting with an abdominal mass, large head and projectile vomiting. Following removal of the renal tumor, the mass arising from the superior vermis about 6 cm in diameter was removed by a combined right occipital transtentorial and suboccipital approach. The patient had been well for 3 months after surgery followed by chemotherapy but died eventually of tumor recurrence in the abdomen. Reported cases of malignant rhabdoid tumor of the kidney associated with brain tumor are reviewed and its characteristics are discussed.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of sellar chordoma mimicking a non-functioning pituitary adenoma with survival of more than 10 years. 鞍脊索瘤模仿无功能垂体腺瘤1例，存活超过10年。
Noshuyo byori = Brain tumor pathology Pub Date : 1993-01-01
T Kagawa, M Takamura, K Moritake, A Tsutsumi, T Yamasaki
{"title":"A case of sellar chordoma mimicking a non-functioning pituitary adenoma with survival of more than 10 years.","authors":"T Kagawa,&nbsp;M Takamura,&nbsp;K Moritake,&nbsp;A Tsutsumi,&nbsp;T Yamasaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rare case of sellar chordoma occurring in a 67-year-old woman who survived for more than 10 years is presented. Clinical signs and symptoms masqueraded as a non-functioning pituitary adenoma with visual disturbance and hypopituitarism. Initial computed tomography (CT) showed an intrasellar mixed dense mass with suprasellar extension, accompanied by non-homogeneous contrast enhancement. Partial removal of the mass was accomplished via right fronto-temporal craniotomy. Histological examination revealed a typical chordoma with no malignancy. After postoperative irradiation, the patient was discharged with clinical improvement. Serial CT and magnetic resonance imaging 8 years after treatment disclosed a regrowth of the intrasellar lesion, which extended to the sphenoid sinus and clivus, accompanied by non-homogeneous contrast enhancement. The patient underwent subtotal removal of the recurrent tumor through a sublabial transsphenoidal approach. Histological examination confirmed the previous diagnosis. Immunohistochemical study demonstrated positive cytoplasmic expression of vimentin, epithelial membrane antigen, keratin and S-100 protein, in contrast with a lack of appearance of carcinoembryonic antigen. After reoperation, she completely recovered and has survived for more than 10 years with good quality of life.</p>","PeriodicalId":79360,"journal":{"name":"Noshuyo byori = Brain tumor pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19210316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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