{"title":"Cardiac metastasis of malignant melanoma: where are we standing?","authors":"T. Velho, N. Guerra, A. Nobre","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.2.50-51","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.2.50-51","url":null,"abstract":"Melanoma is the most severe neoplasm of the skin, still having a poor prognosis despite all the efforts and discoveries in the past few years. Targeted therapies improved treatment options for melanoma, bringing new hopes for patients with advanced and metastized melanoma. Currently, vemurafenib, dafrafenib, ipilimumab, pembrolizumab and trametinib are just some of the drugs approved by the United States Food and Drug Administration (FDA) for clinical use.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70038900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kamal, S. E. Al-Elwany, A. Ghoneim, Ahmed Elminshawy
{"title":"Wall motion score index predicts mortality after coronary artery bypass grafting in patients with viable non-functioning myocardium","authors":"Y. Kamal, S. E. Al-Elwany, A. Ghoneim, Ahmed Elminshawy","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.2.39-40","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.2.39-40","url":null,"abstract":"Coronary artery bypass grafting (CABG) has better survival than medical treatment in patients with left ventricular (LV) dysfunction. Assessment of myocardial viability is crucial to predict survival benefit after CABG. Our recent work determined higher prognostic value of echocardiographic wall motion score index (WMSI) than left ventricular ejection fraction (LVEF) in patients underwent CABG with viable myocardium and LVEF <50%. Thus, it is important to determine the extent of nonviable as well as viable myocardium in patients with low LVEF. Also, in the absence of high modality imaging studies like cardiac magnetic resonance (CMR) and to avoid the radiation hazards of radionuclide studies, assessment of WMSI in addition to LVEF can give accurate data of the magnitude of myocardial damage and can predict survival after CABG in patients with systolic LV dysfunction.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"24 1","pages":"39-40"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Cormatrix? porcine extracellular matrix and pericardial patch augmentation for tricuspid valve leaflet reconstruction - A singlecenter experience.","authors":"D. M. Røpcke","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.1.1-7","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.1.1-7","url":null,"abstract":"Background and aim: Leaflet augmentation to treat restrictive mitral leaflet motion in type IIIB mitral regurgitation is well-known. Leaflet augmentation of the tricuspid valve is less well described. The aim of this retrospective study was to assess short- and long-term valve function and patient outcome in all patients receiving tricuspid valve leaflet augmentation with either Cormatrix or bovine/autologous pericardium in our institution from 2007 to 2016. Materials and methods: NYHA class, diagnosis, type of surgery and health state were found through chart review. Echocardiography exams before surgery, 1 month after, 6 months after, and latest exam were analyzed regarding biventricular function, valve function, leaflet mobility and –thickness. Results: In eight patients; Cormatrix (n=4), bovine pericardium (n=3), and autologous pericardium (n=1) were used for 7 anterior leaflet extensions and 1 septal leaflet extension. Follow-up ranged from 6 to 132 months. Three patients had died, two in the Cormatrix group, and one in the pericardial group. Over time, coaptation length (12 ± 5 mm vs. 8 ± 3 mm, p=0.03) decreased significantly in the Cormatrix group, while none of the other parameters differed significantly. A tendency towards reduced leaflet mobility and thickening of the pericardialextended leaflets were seen over time. Conclusion: Cormatrix and pericardium as patch material for tricuspid leaflet extension are comparable regarding valve performance and durability of the repair in this study, though resorption of Cormatrix material seems to take place leading to decreasing coaptation height. This is a sign of tissue remodelling. Leaflet mobility was reduced in the pericardial repair group and may likely be related to thickening of pericardial patch material that occurred over time.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"1 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70038611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Muñoz, D. Domingo-Valero, Alicia Maceira-González, J. Rueda-Soriano, F. Valera, J. I. Carrasco, Alej, R. Sanchez-Vazquez, A. Montero-Argudo
{"title":"Usefulness of assessing the descending aorta flow pattern for predicting the need for intervention in patients with aortic coarctation","authors":"B. Muñoz, D. Domingo-Valero, Alicia Maceira-González, J. Rueda-Soriano, F. Valera, J. I. Carrasco, Alej, R. Sanchez-Vazquez, A. Montero-Argudo","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.1.24-29","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.1.24-29","url":null,"abstract":"Background: Nowadays, evaluation of the need for intervention in patients with aortic coarctation (AC) is based on anatomical and clinical data. The purpose of the study was to analyze the utility of assessing flow in the thoracic descending aorta using magnetic resonance imaging (MRI) in patients with AC. Methods: Patients with a diagnosis or suspicion of AC, who underwent MRI study between 2008-2016 in a single tertiary center, were retrospectively studied. MRI standardized protocol included gadolinium enhanced angiographic 3-D sequences to evaluate relative stenosis (RS) and phase contrast imaging to assess flow in the descending aorta. Results: 106 patients {70 men (66%), mean age 22 ± 17 years} were included. Of these, 28 (26%) required surgical intervention during the first year after evaluation and 9 (9.3%) required percutaneous treatment. AUROC curves were applied to find best cut-off points of imaging variables. Imaging variables were entered into a multivariate logistic regression model including the presence of arterial hypertension. Percentage of flow increase was shown to be an independent predictor of the need for an intervention (OR, 7.2; 95%CI, 1-20; p=0.03) and adding this parameter in the standard work-up represented a significant increase in diagnostic accuracy (S, 85%; Sp, 89%; vs. S, 62%; Sp, 92%). Conclusion: physiological assessment of flow pattern in descending aorta by MRI significantly increases the ability to evaluate the need for invasive treatment in AC patients beyond standard clinical and anatomical study.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"01 1","pages":"24-29"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IMLAD is not a contraindication for OPCAB","authors":"A. Mahmoud","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.2.41-43","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.2.41-43","url":null,"abstract":"The intra-myocardial LAD is totally different from the myocardial bridging despite some authors do not discriminate sharply between both categories. The bridge in most cases is a limited length of the LAD covered by muscle fibers that squeeze the LAD in systole meanwhile the muscle fibers of the intra-myocardial LAD just cover it without significant dynamic closure. The covered part of the LAD in some cases is not atherosclerotic [7-10]. The LAD may be embedded in the epicardial fat and it is just covered by variable thickness of fat or might be covered with transverse (perpendicular) myocardial fibers for variable distances of its length or depth. This might hinder some surgeons to identify the most important target in the CABG procedure; the LAD [8-10].","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chighaly El Hadj Sidi, I. Mgarrech, A. Tarmiz, S. Jerbi
{"title":"External validation of European System for Cardiac Operative Risk Evaluation II in a Tunisian population","authors":"Chighaly El Hadj Sidi, I. Mgarrech, A. Tarmiz, S. Jerbi","doi":"10.35841/cardiovascular-surgery.2.1.10-17","DOIUrl":"https://doi.org/10.35841/cardiovascular-surgery.2.1.10-17","url":null,"abstract":"Objective: The main objective of this study is to evaluate the performance of the predictive model (EuroSCORE II) on a Tunisian population in order to validate its use in our country. Methods: This is a retrospective study of data from 418 adult patients undergoing cardiac surgery with cardiopulmonary bypass between 1st January 2015 and 31 December 2016 in the department of cardiovascular and thoracic surgery of the Sahloul University Hospital of Sousse. The EuroSCORE ΙΙ is calculated using the application validated on the site www.euroscore.org. The performance of the score is evaluated by analyzing its discriminative power by constructing the ROC curve and analyzing its calibration using the Hosmer-Lemeshow statistics. Results: The EuroSCORE II shows good discriminative power in our population with an area under the ROC curve >0.7 in all study groups (0.864 ± 0.032 for general cardiac surgery, 0.822 ± 0.061 for coronary surgery, 0.864 ± 0.052 for valvular surgery, and 0.900 ± 0.041 for urgent cardiac surgery). The model appears to be calibrated as well by obtaining ρ values above the statistical significance level of 0.05 (0.638 for general cardiac surgery, 0.543 for coronary surgery, 0.179 for valvular surgery, and 0.082 for urgent cardiac surgery). Conclusion: The EuroSCORE II presents acceptable performance in our population, attested by a good discriminative power and an adequate calibration.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"2 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robot assisted thoracic surgery: a review of current literature","authors":"Charles D Ghee, W. Vigneswaran","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.3.71-69","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.3.71-69","url":null,"abstract":"Background: Minimally invasive surgical approaches are generally desired and recommended for many thoracic procedures as they preserve function and allow for more rapid recovery of patients. Despite these advantages, the adaptation has been poor. The robotic approach allowing more intuitive movement, greater flexibility, and high definition 3D vision appears to encourage surgeons to adapt the technique. Methods: This review examines the recent English lit of the early surgical experience of the da Vinci robotic system in the treatment of lung cancer, esophageal resection and mediastinal pathology. Conclusion: The application of robotic technology to thoracic surgery has proven to be at least comparable to open or video assisted thoracoscopic techniques in several areas and in some, possibly superior. If the widespread application of robotic technology allows greater access to minimally invasive thoracic surgery, with equivalent or superior oncological and perioperative outcomes, then it seems logical that robotic technique will become the standard for many general thoracic surgical procedures.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which strategy should be chosen for ischemic free wall rupture on-pump or off-pump?","authors":"Y. Misawa","doi":"10.35841/CARDIOVASCULAR-SURGERY.1.2.48-49","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.1.2.48-49","url":null,"abstract":"In 2017, I reported sutureless repair as a treatment for ischemic heart rupture, and found that an offpump technique using fibrin glue sheets or other materials might contribute to excellent clinical results. In a similar case, Ishii and colleagues reported a patient who underwent sutureless repair with hemostat materials on the bleeding site without cardiopulmonary bypass. Even today, conventional repair under cardiopulmonary bypass leads to unsatisfactory results. A case of a huge pseudoaneurysm after such a repair of left ventricular wall rupture was reported. Although this kind of repair is a simple procedure for ischemic rupture of the left ventricle, clinicians should consider that it carries a potential risk of aneurysmal formation after surgery.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"22 1","pages":"48-49"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70038841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: Transcatheter aortic valve implantation in morphologically complex root-aneurysms.","authors":"B. Winkler, M. Grabenwöger, M. Mach","doi":"10.35841/cardiovascular-surgery.1.2.44-45","DOIUrl":"https://doi.org/10.35841/cardiovascular-surgery.1.2.44-45","url":null,"abstract":"","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew P. Fahrenkopf, John P. Kelpin, Edward Murphy, E. Komorowska‐Timek
{"title":"Chest wall desmoid tumor after double lung transplantation","authors":"Matthew P. Fahrenkopf, John P. Kelpin, Edward Murphy, E. Komorowska‐Timek","doi":"10.35841/CARDIOVASCULAR-SURGERY.2.1.1-5","DOIUrl":"https://doi.org/10.35841/CARDIOVASCULAR-SURGERY.2.1.1-5","url":null,"abstract":"Desmoid tumors pose a number of unique challenges to treating physicians. They have an unpredictable clinical course, aggressive nature, and predilection for recurrence after resection. They frequently develop in areas of previous trauma and have also been thought to be sensitive to hormonal stimuli. Conservative management is often recommended as a primary therapeutic option. Surgery becomes necessary for those patients with symptomatic and/or progressively enlarging lesions. Complete resection is often considered the “gold standard”, but surgeons should always consider minimizing morbidity and maximizing function. There are a limited number of reports in the literature describing desmoid tumors after solid organ transplantation. Here, we report a 66-year-old gentleman who was found to have a mass on his right chest wall two years after lung transplantation. The patient was initially monitored with serial radiographic imaging. Rapid growth prompted a tissue biopsy, revealing a desmoid tumor. Continued expansion and invasion of the lesion into the surrounding osteocutaneous structures required surgical intervention. En bloc resection of the mass with immediate chest wall reconstruction was performed. New lesions developing after transplantation must be monitored with scrutiny. Desmoid tumors, though rare, should be considered in this differential diagnosis. Early diagnosis may decrease patient morbidity by reducing the extent of resection.","PeriodicalId":79324,"journal":{"name":"Cardiovascular surgery (London, England)","volume":"2 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70039386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}