Cardiac metastasis of malignant melanoma: where are we standing?

Abstract

Melanoma is the most severe neoplasm of the skin, still having a poor prognosis despite all the efforts and discoveries in the past few years. Targeted therapies improved treatment options for melanoma, bringing new hopes for patients with advanced and metastized melanoma. Currently, vemurafenib, dafrafenib, ipilimumab, pembrolizumab and trametinib are just some of the drugs approved by the United States Food and Drug Administration (FDA) for clinical use.