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Annals of allergy最新文献

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Lyme disease, Rocky Mountain spotted fever, ehrlichiosis: emerging and established challenges for the clinician. 莱姆病、落基山斑疹热、埃利希体病:临床医生面临的新挑战和既定挑战。
Annals of allergy Pub Date : 1994-07-01
B A Jantausch
{"title":"Lyme disease, Rocky Mountain spotted fever, ehrlichiosis: emerging and established challenges for the clinician.","authors":"B A Jantausch","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>The goal of this review is to facilitate the management of patients with tick-associated diseases. This article will discuss the epidemiology, clinical diagnosis, and antimicrobial therapy of Lyme disease, Rocky Mountain spotted fever, and ehrlichiosis.</p><p><strong>Data sources: </strong>References are limited to the English language and extend back to the beginning of the twentieth century. The human and veterinary literature were reviewed. Sources include computerized databases and bibliographies of recent articles and books.</p><p><strong>Study selection: </strong>Papers were selected on the basis of their timeliness, explanation of important findings by major investigators, extrapolation of clinical data from large patient populations, and clarification of controversial issues. Approximately 50% of the articles initially reviewed are included in the bibliography.</p><p><strong>Results: </strong>Standardization of laboratory testing for Lyme disease should facilitate more accurate diagnosis in the future. Clinical diagnosis of Rocky Mountain spotted fever and ehrlichiosis prior to laboratory confirmation is necessary in order to ensure timely institution of antimicrobial therapy.</p><p><strong>Conclusions: </strong>Knowledge of endemic regions and seasonal cycles of vectors, varying clinical presentations of disease and appropriate utilization of the laboratory are critical for the appropriate diagnosis and management of patients with tick-associated diseases.</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"73 1","pages":"4-11; quiz 11-2"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19024661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum immunoglobulins and IgG subclass levels in adults with chronic sinusitis: evidence for decreased IgG3 levels. 成人慢性鼻窦炎患者血清免疫球蛋白和IgG亚类水平:IgG3水平下降的证据
Annals of allergy Pub Date : 1994-06-01
M Armenaka, J Grizzanti, D L Rosenstreich
{"title":"Serum immunoglobulins and IgG subclass levels in adults with chronic sinusitis: evidence for decreased IgG3 levels.","authors":"M Armenaka,&nbsp;J Grizzanti,&nbsp;D L Rosenstreich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum immunoglobulin class and IgG subclasses were measured in 30 adult patients with chronic sinusitis documented by CT scans of the paranasal sinuses. Results were compared to 30 age-and-sex matched patients with chronic rhinitis who had normal sinus CT scans, and a matched group of asymptomatic, healthy subjects. None of the patients was taking oral corticosteroids and none had ever received allergen immunotherapy. IgA deficiency was present in 3% (2/60) of the patients with chronic rhinitis or sinusitis and IgG deficiency was seen in another two (3%). None of the normals had low IgA or IgG. Low levels of IgG1 or IgG3 were found in some patients in all three groups, while none had low IgG2 levels. Serum levels of IgG, IgA, IgM, IgG1, IgG2, and IgG4 were not significantly different between the groups. Mean serum IgG3 levels, however, were significantly lower in the chronic sinusitis group than the chronic rhinitis group (P < .003) or the normals (P < .0005). The incidence of below normal levels of IgG3 was also more frequent in chronic sinusitis than in chronic rhinitis (P < .04) or normals (P < .002). Patients in the chronic sinusitis group had a high incidence of asthma (57%) and atopy (45%) but there was no difference in immunoglobulin class or IgG subclass levels in matched asthmatics compared with nonasthmatic patients with chronic sinusitis. Atopic patients with chronic sinusitis had a higher frequency of IgG3 subclass deficiency than nonatopics (P = .04). Normalization of low immunoglobulin class or IgG subclass levels that coincided with clinical improvement was documented in two patients with sinusitis.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"507-14"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of acrivastine and terfenadine on skin reactivity to histamine. 吖伐他汀和特非那定对皮肤组胺反应性的影响。
Annals of allergy Pub Date : 1994-06-01
F Leynadier, M Murrieta, J Dry, J N Colin, C Gillotin, D Steru
{"title":"Effects of acrivastine and terfenadine on skin reactivity to histamine.","authors":"F Leynadier,&nbsp;M Murrieta,&nbsp;J Dry,&nbsp;J N Colin,&nbsp;C Gillotin,&nbsp;D Steru","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The response to the histamine hydrochloride prick skin test was studied in 24 healthy volunteers who received, in random order and at least four days apart, acrivastine (8 mg), terfenadine (120 mg), and placebo. The tests were performed on either side of the back before and at the time of administration (single dose), then every 30 minutes for two hours, and every hour for the following four hours. Evaluation was based on the mean of two measurements of the surface area of the wheal-and-flare reaction accompanied by assessment of topical pruritus. The response to histamine was decreased markedly in the two active treatment groups. Although within one hour of injection, the activity of both antihistamines was consistently greater than that of placebo, the kinetics of action of the two products nevertheless differed; indeed acrivastine was active against flare and wheal earlier (within 30 minutes); terfenadine proved to be more active than acrivastine only on flare and only at the later times (four, five, and six hours). The safety study primarily demonstrated drowsiness in one-fourth of the patients receiving placebo and active treatment.</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"520-4"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18910770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway responsiveness to methacholine and risk of asthma in patients with allergic rhinitis. 变应性鼻炎患者气道对甲胆碱的反应性与哮喘的风险。
Annals of allergy Pub Date : 1994-06-01
L Prieto, J M Bertó, V Gutierrez
{"title":"Airway responsiveness to methacholine and risk of asthma in patients with allergic rhinitis.","authors":"L Prieto,&nbsp;J M Bertó,&nbsp;V Gutierrez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To find out whether airway hyperresponsiveness is associated with a greater risk of asthma in subjects with allergic rhinitis, 66 nonasthmatic patients with allergic rhinitis underwent inhalation challenge with methacholine. Each patient was reevaluated prospectively at least once each year and a diagnosis of asthma was accepted if the subject developed episodic wheezing and/or cough plus airway obstruction and at least a 15% increase in FEV1 after inhaled salbutamol. Those subjects who developed asthma and ten individuals who did not develop asthma were rechallenged after the first asthma symptoms or at the end of the followup period, respectively. Risk of developing asthma during the followup period (mean of 43.8 months, range 36 to 70) was similar (P > .05) in those individuals who previously had airway hyperresponsiveness (2 of the 19 patients), when compared with subjects who were previously nonresponders (4 of the 47 patients). Further, in those subjects who developed asthma, geometric mean (range) PC20 decreased from 11.75 (0.40 to 50) during the initial evaluation to 1.66 (0.15 to 11.07) mg/mL after the first asthma symptoms (P < .05). No significant modifications of PC20 were detected in subjects who did not develop asthma. We conclude that a single determination of methacholine PC20 is not a reliable marker of the subsequent development of asthma in patients with allergic rhinitis.</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"534-9"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of electric heating carpet on house dust mites. 电热地毯对室内尘螨的影响。
Annals of allergy Pub Date : 1994-06-01
M Shibasaki, H Takita
{"title":"Effect of electric heating carpet on house dust mites.","authors":"M Shibasaki,&nbsp;H Takita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An electric heating carpet (EHC) that had been especially modified to produce a steady surface temperature of 45 to 50 degrees C was set up in the bedroom of an asthmatic patient, and the density of floor dust mites in this room was compared monthly for 2 years with that in two non-EHC control rooms. When the EHC was used during the mite-growing summer season, the monthly variation in mite density in the EHC room was almost parallel to that in the non-EHC rooms, with a preponderance of floor mites in the non-EHC rooms. In contrast, when the EHC was used during the winter season, the density of floor mites in the EHC room increased as compared with that in the non-EHC rooms, and the ratio of mite density in the EHC room to that in the non-EHC rooms was transiently reversed during this period.</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"541-5"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bronchiolitis obliterans. 闭塞性支气管炎。
Annals of allergy Pub Date : 1994-06-01
C G Baum
{"title":"Bronchiolitis obliterans.","authors":"C G Baum","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"546"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Macronodular pulmonary infiltrates in a patient with chronic asthma and productive cough. 慢性哮喘伴咳嗽患者肺大结节性浸润。
Annals of allergy Pub Date : 1994-06-01
M Alazard, S C Siegel, D Tashkin
{"title":"Macronodular pulmonary infiltrates in a patient with chronic asthma and productive cough.","authors":"M Alazard,&nbsp;S C Siegel,&nbsp;D Tashkin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"491-7"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pubic itching due to food allergy. 食物过敏引起的阴部瘙痒。
Annals of allergy Pub Date : 1994-06-01
J S Hardy
{"title":"Pubic itching due to food allergy.","authors":"J S Hardy","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"546"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of complement determinations in human disease. 补体测定在人类疾病中的应用。
Annals of allergy Pub Date : 1994-06-01
M M Glovsky
{"title":"Applications of complement determinations in human disease.","authors":"M M Glovsky","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"477-86; quiz 486-90"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoglobulin studies in children with inflammatory bowel disease. 儿童炎症性肠病的免疫球蛋白研究
Annals of allergy Pub Date : 1994-06-01
J D Gryboski, T Buie
{"title":"Immunoglobulin studies in children with inflammatory bowel disease.","authors":"J D Gryboski,&nbsp;T Buie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum immunoglobulin A, and G subclasses were measured in patients with ulcerative colitis, Crohn's disease, and in normal controls. Significant differences were noted in elevated total gamma globulin in both disease groups: in elevated IgG1 in ulcerative colitis and elevated IgG2 in patients with Crohn's disease. These differences were not significantly related to disease activity in either disease although higher levels were observed in those with moderate and severe disease.</p>","PeriodicalId":7931,"journal":{"name":"Annals of allergy","volume":"72 6","pages":"525-7"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19193670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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