{"title":"Epithelial inclusions in the lymph nodes. Diagnostic, histogenetic, and prognostic problems.","authors":"G Gricouroff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The capacity of epithelial cancer to invade the lymph nodes is a common notion. Adenopathy may, on rare occasions, be the first clinical sign of an unrecognized cancer. Exceptionally following the discovery in a lymph node of malignant-looking epithelial inclusions, a complete examination of the patient will reveal no primary tumor and the case will remain unexplained. Conversely, it may also happen that upon microscopic examination of the nodes which, for one reason or another, have been removed, benign-looking epithelial inclusions are discovered. In women, these are most often endometrial type glands; in men, they are usually thyroid follicles. The diagnostic, histogenetic, and prognostic problems raised by these various inclusions are, of course, different; however, their one point in common--the ectopic presence of epithelial tissue in a lymph node--and the controversy concerning the benign or malignant nature of certain inclusions, incite this comprehensive study.</p>","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 4","pages":"285-93"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18179614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Squamous cell carcinoma arising in endometriosis.","authors":"K T Chen, M Weilert","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 4","pages":"343-6"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18182822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The expression of human chorionic gonadotropin in the female genital tract: localization by the immunoperoxidase technique.","authors":"C M Fenoglio, T Hayata, C P Crum, R M Richart","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Four hundred eighty-eight lesions from 456 patients were surveyed for the production of hCG using the immunoperoxidase technique. HCG immunoreactivity was found in 9.1% of the total number of cases studied. The 10% of ovarian cancers expressing hCG included serous, endometrioid, and germ cell tumors. Eighteen point nine percent of neoplastic cervices were positive for hCG; the highest rate of expression was in invasive cancers. Eighteen point nine percent of endometrial cancers were hCG positive; poorly differentiated tumors had the highest percent of marker expression. The significance of \"ectopic\" hCG expression in nontrophoblastic gynecologic neoplasms is discussed.</p>","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 2","pages":"97-103"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18094016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spindle cell carcinoma of the vulva.","authors":"P Copas, M Dyer, F V Comas, D J Hall","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 3","pages":"235-41"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18133756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of diagnostic imaging in the staging of gestational trophoblastic disease.","authors":"A G Williams, F A Mettler, J D Wicks","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gestational trophoblastic disease (GTD) is a group of tumors with a cure rate of 90-100% with appropriate treatment. The patients with a poor prognosis have metastatic disease involving structures other than the pelvic organs or the lungs. The medical records of 70 patients with histologically proven GTD were reviewed to determine the usefulness of diagnostic imaging modalities in the staging and follow-up of GTD. The level of chorionic gonadotropin (hCG) is more sensitive in determining the persistence of disease or its response to therapy, but is of little use in evaluating the site of metastases. Diagnostic imaging modalities are most useful in determining the presence and sites of metastases so that appropriate treatment is instituted.</p>","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 2","pages":"159-63"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17347279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Syringoma of the vulva in postmenopausal age.","authors":"G Ghirardini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 4","pages":"325-6"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18182820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Value of computed tomography (CT) in an obstetrical emergency.","authors":"D A Baker, P Catalano, P Makowski, M Gibson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 1","pages":"53-6"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18121701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal blood analysis. I. Effect of delayed collection.","authors":"F Silverman, C Antoine, B K Young","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Umbilical blood was analyzed for pH, pO2, pCO2, HCO3-, base excess, and plasma lactate to evaluate possible errors of fetal scalp blood analysis. Two studies to determine the effect of delayed collection and exposure to air on fetal blood acid-base measurement analyzed anaerobically collected umbilical blood in syringe and capillary samples. In the first study, 37 samples were analyzed and then placed in small droplets on a glass slide and exposed for 30 seconds and 60 seconds respectively. These samples were then collected and reanalyzed. No significant change was noted through 1 minute of exposure in any of the acid-base parameters measured. In the second study, 34 samples were again analyzed and then exposed in droplets for a full 5 minutes. Differences in measurement of pO2, base excess, and plasma lactate remained insignifiicant even up to 5 minutes. The results of this study demonstrate that the occasional slow scalp blood collection or admixture with air do not present a significant obstacle to proper use of fetal acid-base analysis.</p>","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":" ","pages":"87-91"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35220831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P A Miles, G A Herrera, H Greenberg, G Rawding-Patterson
{"title":"Primary carcinoid tumor of the uterine cervix presenting as an adenosquamous carcinoma. The importance of electron microscopy and immunohistochemistry in evaluating poorly differentiated cervical neoplasms.","authors":"P A Miles, G A Herrera, H Greenberg, G Rawding-Patterson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary carcinoid tumors of the uterine cervix are uncommon gynecologic neoplasms. An unusual case of this neoplasm is presented that was originally diagnosed as a poorly differentiated adenosquamous cervical carcinoma. A subsequent metastatic pulmonary nodule was discovered 13 months later with the unexpected histologic and ultrastructural features of a carcinoid tumor. The primary cervical malignancy was reassessed ultrastructurally and the original diagnosis was changed to that of a poorly differentiated carcinoid tumor. By using immunoperoxidase techniques, it was observed that serotonin granules were present in the neoplastic cells of the lung and cervix, confirming the carcinoid nature of the tumor. This case differs from the majority of those reported as poorly differentiated cervical carcinoids in that it did not resemble an undifferentiated small cell (oat cell) carcinoma, but was more typical of an adenosquamous carcinoma. This case supports the role of electron microscopy and immunohistochemistry in the complete evaluation and diagnosis of less-differentiated cervical neoplasms in order to specifically identify the primary cell (cells) of origin. Only in this way can one definitively support the diagnosis of a primary carcinoid tumor and perhaps, with this knowledge, the clinicobiologic behavior of this cancer can be altered and possibly improved by initiating different or adjunctive treatment modalities.</p>","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 4","pages":"327-37"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17815298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute fatty liver of pregnancy. Increased survival by early recognition and aggressive therapy.","authors":"S J Ahola, B T Lyman, A F Hogan, R E Schmid","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79216,"journal":{"name":"Diagnostic gynecology and obstetrics","volume":"4 1","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18121704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}