Clinical and experimental dialysis and apheresis最新文献_第4页

Hypophosphatemia-induced hypercalcemia during acute renal failure. 急性肾功能衰竭时低磷血症引起的高钙血症。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076050

R F Gagnon, P Pajel, M Kaye

引用次数: 3

Role of mitochondria in ischemic acute renal failure. 线粒体在缺血性急性肾功能衰竭中的作用。

Clinical and experimental dialysis and apheresis Pub Date : 1983-01-01 DOI: 10.3109/08860228309076039

T J Burke, D R Wilson, M Levi, J A Gordon, P E Arnold, R W Schrier

{"title":"Role of mitochondria in ischemic acute renal failure.","authors":"T J Burke, D R Wilson, M Levi, J A Gordon, P E Arnold, R W Schrier","doi":"10.3109/08860228309076039","DOIUrl":"https://doi.org/10.3109/08860228309076039","url":null,"abstract":"Ischemic ARF is characterized by progressive mitochondrial accumulation of Ca++ which is inversely correlated with the level of oxidative phosphorylation. At least two possibilities exist which would be compatible with these data 1) depressed respiration leads to Ca++ accumulation or 2) increased mitochondrial Ca++ leads to reduced mitochondrial respiration. We favor the latter hypothesis for the reasons outlined above; furthermore, this conclusion is supported by the observations of Lehninger, made some 20 years ago: first, that either oxidative phosphorylation or mitochondrial Ca++ accumulation can be accomplished by intact mitochondria but that these events cannot occur simultaneously and second, that Ca++ accumulation takes precedence over oxidative phosphorylation. Our observation made during post-ischemic reflow that mitochondrial Ca++ accumulation occurs to a significant degree, strongly suggest a potential role for mitochondrial Ca++ overload in the pathogenesis of ARF. Nevertheless, this is not an irreversible pathogenetic process. Clearly, impermeant solutes, vasodilators and Ca++ membrane blockers will alter the natural history of this injury and prevent the severity of the functional defect. A common mechanism of action may involve direct or indirect modification of cellular Ca++ overload in renal vascular and epithelial tissue. The vascular smooth muscle may then revert to a less constricted state with a subsequent more rapid recovery of renal blood flow and that the renal epithelial cell death may be minimized thereby reducing tubular obstruction.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228309076039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17933394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Evaluation of low flow long dwell chronic intermittent peritoneal dialysis. 低流量长时间慢性间歇腹膜透析的评价。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050812

P T Doody, M Goldberg

引用次数: 0

The evaluation of cerebral atrophy in renal dialysis patients by computerized tomography. 计算机断层扫描对肾透析患者脑萎缩的评价。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050817

C Papageorgiou, P Ziroyannis, J Vathylakis, A Grigoriadis, Z Kapsalakis

引用次数: 2

Eosinophilic peritonitis. 嗜酸性粒细胞的腹膜炎。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209049850

B S Spinowitz, R A Golden, J H Rascoff, C Charytan

引用次数: 7

Technique for implantation of the Toronto-Western catheter at the Booth Memorial Medical Center. 在布斯纪念医疗中心植入多伦多西部导管的技术。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209049851

S Fink, B S Spinowitz, C Charytan

引用次数: 0

Treatment of hypertension in dialysis and essential hypertension patients with nifedipine. 硝苯地平治疗透析高血压及原发性高血压患者。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209049856

H E Eliahou, A Iaina, R Schneider, D Cohen, D Goldfarb, M Gross

{"title":"Treatment of hypertension in dialysis and essential hypertension patients with nifedipine.","authors":"H E Eliahou, A Iaina, R Schneider, D Cohen, D Goldfarb, M Gross","doi":"10.3109/08860228209049856","DOIUrl":"https://doi.org/10.3109/08860228209049856","url":null,"abstract":"The immediate antihypertensive effect of 10 mg nifedipine sublingually (nifedipine test), was measured in 19 chronic renal failure hypertensive patients on dialysis and 34 essential hypertensive patients with normal kidney function. The blood pressure decreased significantly in both groups. The minimal values were observed between 30 and 60 minutes after the sublingual administration of nifedipine. The blood pressure decreased from 178 +/- 3.3/104.0 +/- 3.9 to 136.0 +/- 4.7/87.5 +/- 5.1 mm Hg (p less than 0.001) in dialysis patients and from 176.8 +/- 4.5/107.1 +/- 2.4 to 133.0 +/- 3.0/81.7 +/- 2.2 mm Hg in essential hypertension patients (p less than 0.001). The decrease in blood pressure during the test had a significant positive correlation with the pre-test values. Thirteen hypertensive patients on dialysis and 20 essential hypertensive patients completed 2 weeks of daily oral nifedipine therapy, with a dose of 30 to 40 mg per day. The mean blood pressure at the end of the 2 weeks of treatment decreased from 179.5 +/- 4.5/108.5 +/- 5.3 mm Hg to 154.4 +/- 6.3/82.3 +/- 2.6 mm Hg (p less than 0.001) in dialysis patients, and from 176.8 +/- 5.8/110.3 +/- 2.9 to 151.3 +/- 5.3/93.5 +/- 2.6 mm Hg (p less than 0.001) in essential hypertension patients. The present results reveal that nifedipine has a powerful immediate as well as a long-term antihypertensive action in dialysis patients with high blood pressure. This effect is similar to that obtained in essential hypertensive patients.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209049856","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18196625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Dialytic support of dogs with clinically occurring renal failure: a realistic model of acute renal failure in man. 临床发生肾功能衰竭的狗的透析支持:一个现实的急性肾功能衰竭在人的模型。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050811

S R Ash, J A Thornhill, C R Dhein, A H Rebar

{"title":"Dialytic support of dogs with clinically occurring renal failure: a realistic model of acute renal failure in man.","authors":"S R Ash, J A Thornhill, C R Dhein, A H Rebar","doi":"10.3109/08860228209050811","DOIUrl":"https://doi.org/10.3109/08860228209050811","url":null,"abstract":"In canine veterinary medicine, both acute and chronic renal failure occur relatively frequently, from a variety of causes similar to those in man. However, the normal dog has a very high protein catabolic rate and high endogenous kidney function, and, therefore, requires frequent and highly efficient dialysis, for maintenance during renal failure. We have developed techniques to support the uremic dog with hemodialysis. An experimentally anephric dog, and two dogs with clinically occurring acute renal failure (caused by ethylene glycol intoxication and heat stroke) have been supported with frequent use of hollow fiber dialyzers, using a carotid artery to jugular vein shunt. Patency of shunts was maintained by administration of oral aspirin. A very high urea and creatinine generation rate necessitated daily dialysis during much of the clinical course of renal failure. The experimentally anuric animal was supported for 35 days. The ethylene glycol-induced renal failure animal was euthanized on the 21st day, and the heat stress-induced renal failure animal recovered sufficient intrinsic renal function after 16 days of dialysis for maintenance of life without dialysis.","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050811","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35220365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

High output cardiac failure on maintenance hemodialysis secondary to a post-biopsy renal arteriovenous fistula. 维持性血液透析继发于活组织检查后肾动静脉瘘的高输出量心力衰竭。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050813

R F Gagnon, L R Dufresne, W P Duguid, E C Reid, M Kaye

引用次数: 1

Elimination of requirement for exogenous insulin therapy in diabetic renal failure. 消除外源性胰岛素治疗对糖尿病性肾衰竭的需求。

Clinical and experimental dialysis and apheresis Pub Date : 1982-01-01 DOI: 10.3109/08860228209050815

J A D'Elia, A Kaldany, D G Miller, A Rolla, L A Weinrauch

引用次数: 6