{"title":"The effect of enhancing factor on the immunity of mice against tetanus.","authors":"E Osz, I Barna, R Varró, L Bácskai, L Réthy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Enhancing factor was prepared from spleens of mice primed and reinjected with tetanus toxoid. The culture supernatant was separated by gel chromatography on Sephadex G-150, the resulted fractions were ultrafiltered and their enhancing activity was tested in vivo. The 1st fraction separated by gel chromatography proved to be active.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The circumstances of freezing in the freeze-drying process of haemoderivatives.","authors":"M Fekete, M Kovács, G Tollas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It appears from the experiments of the authors that the macroscopic changes taken place during freezing and heating could be explained by the formation of an eutectic crystalline structure in the case of human plasma and albumin solutions. The temperature interval of eutectic spot formation showed good agreement with the temperature range of initial thawing as determined by the DTA method, i.e. with the working zone freeze-drying. It was possible to determine the maximum temperature of complete solidification from the resistance curves of the haemoderivatives. Judging from the shape of the resistance curves, the phenomenon of undercooling did not emerge with the freezing rate applied. Examining the optimal freezing rate, it appeared on the basis of some quality characteristics of the freeze-dried end-product, that the best results were obtained with --30 degrees C freezing in the case of albumin and plasma, and with --45 degrees C freezing in the case of normal and iv immunoglobulins. But the authors deem it necessary to conduct further experiments in this respect.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"229-36"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Further investigations about the passive transfer of sensitivity caused by anti-thymocyte serum.","authors":"E Osz, L Réthy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Soluble materials were obtained from the spleens and thymuses removed from mice sensitized by anti-thymocyte serum or normal horse serum. These materials were administered to mice. In the mice thus treated, anaphylaxis was provoked by iv inoculation of serum. Irreversible shock did not occur. Reversible anaphylactoid symptoms occured among the animals treated with the supernatants of cells of sensitized animals, in case when these cells have been disrupted by osmotic shock.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"159-62"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12268674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antigen analysis of Staphylococcus aureus strains sensitive and resistant to antibiotics.","authors":"A Jagicza, I Városi, L Sztankov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The analysis of the antigens produced by the disintegration of Staphylococcus aureus (Wood 46, 211, 223 strains) bacteria treated with antibiotics was carried out by the authors with immunochemical methods. It appears from the analyses strikingly that established resistance produces changes in the antigenic structure. This is manifest in the number of the antigen-antibody systems and, within the multiple system, in the character of certain antigens. The decrease in the number of the precipitogens is considerable. In the case of all the three strains, the presence of an antigen band was shown which is identical in the antibiotic-resistant bacteria, but is not to be found in the antigens of the corresponding antibiotic-sensitive bacteria. The authors' experience shows that one possibility of approaching the problem of antibiotic resistance is to clarify with immunochemical methods the differences found in the protein spectra of the antibiotic-resistant varieties.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"215-22"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of antigen-type immunosorbents prepared by different ways.","authors":"F Peterfy, Z Csizer, I Kiss","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>7 types of IgG-containing immunosorbents were compared from different respects by using them for adsorption of antibodies. The human IgG was insolubilized by ethylchlorophormate and glutaraldehyde, thereafter it was bound to activated agarose and polyacrylamide gels and 3 new types of polyacrylamide immunosorbent were prepared by polymerizing the acrylamide in the protein solution and by coupling the protein to the matrix by different ways. Using batch technique, the ethylchlorophormate, the glutaraldehyde and some of the new polyacrylamide immunosorbents proved to be useful, but in almost every respect the immunosorbent prepared from Sepharose gel was the best.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"85-92"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of saliva immunoglobulins in monoclonal gammopathies.","authors":"J Lajos, A Komán, E Boromissza, M Rojti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Salivary immonoglobulins of patients with multiple myeloma, lymphoid leukaemia, agammaglobulinaemia and of normal healthy adults were examined. Higher IgG level was identified in 4 cases IgG monoclonal gammopathy. In these cases extremely large quantities of IgG monoclonal protein were transmitted from serum into salivary secretions. On the basis of the results it appears that monoclonal IgA is transferred to external secretions in patients with IgA monoclonal gammopathy. High IgM level was found in both serum and saliva of agammaglobulinaemic patients. \"IgM secretory component\" complex could be identified in saliva. In lymphoid leukaemic patients the salivary immunoglobulins presented normal values except of a patient whose tigA lacked in serum and also in saliva.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Some comments on the estimation of the potency of pertussis vaccines.","authors":"Z Csizér, J Zsidai","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"11-6"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experiments for the production of graft-versus-host reaction in adult and infantile mice by means of human immunocompetent cells.","authors":"L Réthy, E Osz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By administering anti-mouse ATS five times to random-bred Swiss albino mice weighing 16-18 and 10-11 g respectively, the authors have tried to produce immunological depression of such a degree which would allow living human leukocytes to cause GVH reaction. On the basis of the results it may be stated that with the serum dosage and manner of treatment applied, the human graft was not able to act against the recipient organism and to produce differences in body weight.</p>","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"18 ","pages":"163-70"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11240589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Results of blood group studies carried out at Rackeve (county Pest, Hungary)].","authors":"B Rex-Kiss, R Szabó, E Hartmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7910,"journal":{"name":"Annales immunologiae Hungaricae","volume":"17 ","pages":"169-81"},"PeriodicalIF":0.0,"publicationDate":"1973-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15329457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}