S. Perez, J.-D. Bouaziz, A. Petit, M. Battistella, T. Mahévas
{"title":"The value of alpha-1 antitrypsin functional testing and genotyping for the diagnosis of the MS variant of alpha-1 antitrypsin deficiency-associated panniculitis","authors":"S. Perez, J.-D. Bouaziz, A. Petit, M. Battistella, T. Mahévas","doi":"10.1016/j.annder.2024.103295","DOIUrl":"10.1016/j.annder.2024.103295","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Poizeau , S. Leducq , L. Fardet , M. Beylot-Barry , Guillaume Chaby , M. Chastagner , F. Corgibet , L. Gouillon , N. Jouan , D. Jullien , A. Acher , F. Amatore , J.-M. Amici , H. Aubert , F. Aubin , N. Beneton , D Bouilly , A.-C. Bursztejn , C. Buzenet , M. Chamaillard-Pujol , B. Guillot
{"title":"Treatment of moderate-to-severe psoriasis in adults: An expert consensus statement using a Delphi method to produce a decision-making algorithm","authors":"F. Poizeau , S. Leducq , L. Fardet , M. Beylot-Barry , Guillaume Chaby , M. Chastagner , F. Corgibet , L. Gouillon , N. Jouan , D. Jullien , A. Acher , F. Amatore , J.-M. Amici , H. Aubert , F. Aubin , N. Beneton , D Bouilly , A.-C. Bursztejn , C. Buzenet , M. Chamaillard-Pujol , B. Guillot","doi":"10.1016/j.annder.2024.103287","DOIUrl":"10.1016/j.annder.2024.103287","url":null,"abstract":"<div><h3>Background</h3><p>New highly effective drugs for moderate-to-severe cutaneous psoriasis are regularly marketed, and the hierarchy of treatments thus requires frequent review.</p></div><div><h3>Objectives</h3><p>A Delphi method was used to enable a structured expert consensus on the use of systemic treatments and phototherapy among adults with moderate-to-severe psoriasis.</p></div><div><h3>Methods</h3><p>The Delphi method consists in achieving a convergence of opinions among a panel of experts using several rounds of questionnaires with controlled feedback between rounds. A two-part Delphi questionnaire was administered online to French psoriasis experts. In the first part, 180 items related to the prescription of systemic treatments and phototherapy for adult patients with moderate-to-severe psoriasis were grouped into 21 sections covering different lines of treatment and different forms of cutaneous psoriasis. The experts voted on each proposal using an ordinal 7-point Likert scale. The second part comprised 11 open-ended questions about special indications for each therapeutic class. These were converted into 101 questions for subsequent rounds. Consensus was deemed to have been reached if more than 80% of the experts agreed with a given proposal.</p></div><div><h3>Results</h3><p>Three rounds of questionnaires were sequentially sent to 35 participants between November 2021 and March 2022. Thirty-three (94%) completed all three rounds. For plaque psoriasis, only methotrexate was recommended by the experts as first-line systemic treatment (89% of votes). Cyclosporin was advocated in pustular and erythrodermic psoriasis, and acitretin was suggested for hyperkeratotic and palmoplantar psoriasis. In the event of failure of or intolerance to non-biological systemic treatments, guselkumab, risankizumab, ixekizumab or secukinumab were recommended by more than 80% of the experts. Tumor Necrosis Factor (TNF) inhibitors remain useful for patients with cardiovascular risk factors. Special indications were provided for each therapeutic class (methotrexate/narrowband ultraviolet B phototherapy, psoralen/ultraviolet A phototherapy, cyclosporin, acitretin, apremilast, TNF inhibitors, interleukin (IL)-12/23 inhibitors, IL-17(R)A inhibitors, and IL-23 inhibitors).</p></div><div><h3>Conclusions</h3><p>This expert consensus statement indicate that newly available IL-17 and IL-23 inhibitors may be favored over TNF and IL-12/23 inhibitors as first-line biologics. The Centre of Evidence of the French Society of Dermatology has drawn up a decision-making algorithm to guide clinicians in the therapeutic management of moderate-to-severe psoriasis.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963824000437/pdfft?md5=fcaadc1a0da475739a7b367b4cdb337a&pid=1-s2.0-S0151963824000437-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Léonie Martin, Sister Françoise-Thérèse (1863–1941), may have had atopic eczema","authors":"N. Kluger, P. Charlier","doi":"10.1016/j.annder.2024.103292","DOIUrl":"10.1016/j.annder.2024.103292","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Berard , K. Chassain , C. Méry , F. Gillaizeau , T. Carton , H. Humeau , N. Navasiolava , S. Rocour , L. Schurgers , M. Kempf , L. Martin
{"title":"Changes in the gut microbiota of pseudoxanthoma elasticum patients","authors":"M. Berard , K. Chassain , C. Méry , F. Gillaizeau , T. Carton , H. Humeau , N. Navasiolava , S. Rocour , L. Schurgers , M. Kempf , L. Martin","doi":"10.1016/j.annder.2024.103290","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103290","url":null,"abstract":"<div><h3>Objective</h3><p>Pseudoxanthoma elasticum (PXE) is a rare autosomal disorder with a variable phenotype that may be modulated by environmental factors. Plasma vitamin K (VK) levels may be involved in the ectopic calcification process observed in PXE. Since VK2 is predominantly produced by the gut microbiota, we hypothesized that changes in the gut microbiota of PXE patients might exacerbate the calcification process and disease symptoms.</p></div><div><h3>Methods</h3><p>Twenty PXE patients were included in the study and 60 gut microbiota profiles from the Biofortis laboratory database were used as controls.</p></div><div><h3>Results</h3><p>The <em>Rhodospirillaceae</em> family was more abundant in the PXE group while the <em>Sphingomonadaceae</em> family was more abundant in the control group. In a PXE severity subgroup analysis, microbiota dispersion was lower in “severe” than in “non-severe” patients, which was confirmed by permutation multivariate analysis of variance at the phylum, family and genus ranks. However, no significant association was found in a model incorporating relative abundance of bacterial families, severity score, and different blood and fecal VK species.</p></div><div><h3>Conclusion</h3><p>These results suggest slight compositional changes in the gut microbiota of PXE patients. Further studies are needed to substantiate their impact on VK metabolism and the calcification process.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141607643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Charvet , T. Mahévas , S. Rivière , D. Gobert , V. Jachiet , V. Panayotopoulos , N. Abisror , E. Ghrenassia , L. Arrive , S. Vignes , A. Mekinian , O. Fain
{"title":"Recurrent cervical swelling syndrome as a rare cause of left supraclavicular edema: Case series and literature review","authors":"E. Charvet , T. Mahévas , S. Rivière , D. Gobert , V. Jachiet , V. Panayotopoulos , N. Abisror , E. Ghrenassia , L. Arrive , S. Vignes , A. Mekinian , O. Fain","doi":"10.1016/j.annder.2024.103286","DOIUrl":"10.1016/j.annder.2024.103286","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963824000425/pdfft?md5=c992452d5dc4b5fc59acbf5c7eca6806&pid=1-s2.0-S0151963824000425-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Leducq , F. Poizeau , G. Chaby , J. Tannous , F. Ballanger-Desolneux , E. Baubion , A. Bertolotti , O. Cogrel , C. Droitcourt , V. Garnier , S. Gautier , L. Hefez , C. Hotz , A.-P. Jonville-Béra , N. Jouan , A. Mahé , E. Mahé , G. Martinho , J. Micallef , T. Puszkarek , O. Chosidow
{"title":"Isotretinoin: Past, present and future. A French perspective","authors":"S. Leducq , F. Poizeau , G. Chaby , J. Tannous , F. Ballanger-Desolneux , E. Baubion , A. Bertolotti , O. Cogrel , C. Droitcourt , V. Garnier , S. Gautier , L. Hefez , C. Hotz , A.-P. Jonville-Béra , N. Jouan , A. Mahé , E. Mahé , G. Martinho , J. Micallef , T. Puszkarek , O. Chosidow","doi":"10.1016/j.annder.2023.103244","DOIUrl":"10.1016/j.annder.2023.103244","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963823000996/pdfft?md5=1fa137aaa86ddbfaf9a95a2e8580d8c9&pid=1-s2.0-S0151963823000996-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141287661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ingen-Housz-Oro , I. Matei , A. Gaillet , J. Gueudry , K. Zaghbib , H. Assier , C. Hua , B. Bensaid , A. Colin , R. Ouedraogo , J. Redlich , E. Courtois , K. Chazelas , E. Sbidian , L. Nakad , E. Bequignon , N. Terkmane , F. Gaultier , F. Schlemmer , G. Do-Pham , N. de Prost
{"title":"French national protocol for diagnosis and management of epidermal necrolysis in adults (Stevens-Johnson syndrome and toxic epidermal necrolysis)","authors":"S. Ingen-Housz-Oro , I. Matei , A. Gaillet , J. Gueudry , K. Zaghbib , H. Assier , C. Hua , B. Bensaid , A. Colin , R. Ouedraogo , J. Redlich , E. Courtois , K. Chazelas , E. Sbidian , L. Nakad , E. Bequignon , N. Terkmane , F. Gaultier , F. Schlemmer , G. Do-Pham , N. de Prost","doi":"10.1016/j.annder.2024.103282","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103282","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963824000383/pdfft?md5=d1473de75db0babd57817718012638ef&pid=1-s2.0-S0151963824000383-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Canu, S. Mary-Prey, A. Legrand, C. Leauté-Labreze
{"title":"Use of spironolactone for the treatment of acne in adolescent girls","authors":"D. Canu, S. Mary-Prey, A. Legrand, C. Leauté-Labreze","doi":"10.1016/j.annder.2024.103281","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103281","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141078061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Barriers and suggestions for improving the implementation of guidelines in the systemic treatment of moderate to severe psoriasis: A literature review","authors":"V. Kalita, D. Abs, A.-C. Bursztejn","doi":"10.1016/j.annder.2024.103280","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103280","url":null,"abstract":"<div><h3>Background</h3><p>Despite the availability of a wide range of therapies for the systemic treatment of moderate to severe psoriasis, many psoriasis patients do not receive adequate treatment, suggesting that guidelines may not be correctly applied by physicians.</p></div><div><h3>Objectives</h3><p>The aim of this study was to analyze data on physicians’ implementation of, and reasons for noncompliance with, guidelines for the systemic treatment of moderate to severe psoriasis.</p></div><div><h3>Methods</h3><p>We conducted a systematic literature review according to the Preferred Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the PubMed and Embase databases for studies on guideline adherence in the systemic treatment of moderate to severe psoriasis. All eligible articles were retrieved in full text and the relevant references of retrieved articles were included.</p></div><div><h3>Results</h3><p>A total of 20 studies were selected. Four studies investigated knowledge of the guidelines, six studies examined their application, and five studies focused on the various barriers to implementation. Finally, five studies discussed ways to improve implementation. Several studies on the quality of psoriasis care have revealed discrepancies between the reality and the optimal care described in national and international guidelines.</p></div><div><h3>Conclusion</h3><p>Various barriers to implementation of recommendations exist, such as economic barriers, lack of dermatologic orientation towards, lack of knowledge of recommendations by other specialists, lack of applicability, and country- and practice-specific features (<em>e.g</em>., different benefit/risk ratios, different reimbursement rates and conditions). This review can help the everyday practitioner to better understand these barriers, which will have a direct impact on improving the quality of life of psoriasis patients.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S015196382400036X/pdfft?md5=dd90a8b5d38d003933b944ce1e62b5a3&pid=1-s2.0-S015196382400036X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141078059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abundant CD30+ lymphocyte infiltrate in idiopathic perniosis","authors":"D. Canu, F. Beltzung, P. Poizac, M.-S. Doutre","doi":"10.1016/j.annder.2024.103279","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103279","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141078060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}