Anesthesiology Research and Practice最新文献

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Effect of Laryngeal Mask Air Way Insertion versus Endotracheal Intubation over Hemodynamic Responses in Pediatrics Patient Who Underwent Ophthalmic Surgery at Menelik II Hospital, Addis Ababa: A Prospective Observational Study Design. 在亚的斯亚贝巴Menelik II医院接受眼科手术的儿科患者中,喉罩气道插入与气管插管对血流动力学反应的影响:一项前瞻性观察性研究设计。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-06-01 eCollection Date: 2020-01-01 DOI: 10.1155/2020/7021641
Mohammed Suleiman Obsa, Azeb Lencha Sholla, Betelhem Girma Baraki, Getahun Dendir Welde, Temesgen Bati Gelgelu, Melese Meleku Kuruche
{"title":"Effect of Laryngeal Mask Air Way Insertion versus Endotracheal Intubation over Hemodynamic Responses in Pediatrics Patient Who Underwent Ophthalmic Surgery at Menelik II Hospital, Addis Ababa: A Prospective Observational Study Design.","authors":"Mohammed Suleiman Obsa,&nbsp;Azeb Lencha Sholla,&nbsp;Betelhem Girma Baraki,&nbsp;Getahun Dendir Welde,&nbsp;Temesgen Bati Gelgelu,&nbsp;Melese Meleku Kuruche","doi":"10.1155/2020/7021641","DOIUrl":"https://doi.org/10.1155/2020/7021641","url":null,"abstract":"<p><strong>Background: </strong>The airway of an anesthetized child is usually maintained with an endotracheal tube or laryngeal mask airway. However, both are related with some level of pressor response which may be risky in several groups of patient.</p><p><strong>Methods: </strong>An institutional-based prospective observational study design was employed. A systematic random sampling technique was used to select study participants. Data were entered into Epi info version 7 and transported to SPSS version 20 for analysis. Normality of the data was checked using Shapiro-Wilk tests. An independent <i>t</i> test was used to determine the mean differences between the two groups while the paired sample <i>t</i> test was used to determine the mean differences within the groups. A <i>p</i> value of less than 0.05 was used as a cut-off point for the presence of association.</p><p><strong>Results: </strong>The changes in systolic and diastolic blood pressure were returned to baseline values at five and three minutes in both groups, respectively. However, the changes in the heart rate and mean arterial pressure returned to baseline values in five minutes in the ETT group and three minutes in the LMA group. At baseline, the difference in systolic blood pressure between the two groups was not statistically significant (<i>p</i>=0.328).</p><p><strong>Conclusions: </strong>A significant hemodynamic pressor response was observed after the insertion of both LMA and ETT groups. However, the LMA group has less hemodynamic change as compared to the ETT group. Therefore, the practice of LMA insertion was strongly recommended.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"7021641"},"PeriodicalIF":1.4,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/7021641","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38069893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial. 地塞米松、昂丹司琼或安慰剂对脊髓麻醉下鞘内吗啡下肢骨科手术患者的恢复质量随机对照试验。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-05-20 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9265698
Eduardo Toshiyuki Moro, Miguel Antônio Teixeira Ferreira, Renyer Dos Santos Gonçalves, Roberta Costa Vargas, Samira Joverno Calil, Maria Alice Soranz, Joshua Bloomstone
{"title":"The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial.","authors":"Eduardo Toshiyuki Moro,&nbsp;Miguel Antônio Teixeira Ferreira,&nbsp;Renyer Dos Santos Gonçalves,&nbsp;Roberta Costa Vargas,&nbsp;Samira Joverno Calil,&nbsp;Maria Alice Soranz,&nbsp;Joshua Bloomstone","doi":"10.1155/2020/9265698","DOIUrl":"https://doi.org/10.1155/2020/9265698","url":null,"abstract":"<p><p>Intrathecal morphine is widely and successfully used to prevent postoperative pain after orthopedic surgery, but it is frequently associated with side effects. The aim of this study was to evaluate the effect of dexamethasone or ondansetron when compared to placebo to reduce the occurrence of these undesirable effects and, consequently, to improve the quality of recovery based on patient's perspective. <i>Methods</i>. One hundred and thirty-five patients undergoing lower extremity orthopedic surgery under spinal anesthesia using bupivacaine and morphine were randomly assigned to receive IV dexamethasone, ondansetron, or saline. On the morning following surgery, a quality of recovery questionnaire (QoR-40) was completed. <i>Results</i>. No differences were detected in the global and dimensional QoR-40 scores following surgery; however, following postanesthesia care unit (PACU) discharge, pain scores were higher in patients receiving ondansetron compared with patients who received dexamethasone. <i>Conclusion</i>. Neither ondansetron nor dexamethasone improves the quality of recovery after lower limbs orthopedic surgery under spinal anesthesia using intrathecal morphine.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"9265698"},"PeriodicalIF":1.4,"publicationDate":"2020-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/9265698","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38029537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effect of Ketamine/Propofol Admixture on Peri-Induction Hemodynamics: A Systematic Review and Meta-Analysis. 氯胺酮/异丙酚混合物对诱导期血流动力学的影响:系统回顾与元分析》。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-05-08 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9637412
Nathan J Smischney, Mohamed O Seisa, Allison S Morrow, Oscar J Ponce, Zhen Wang, Muayad Alzuabi, Katherine J Heise, Mohammad H Murad
{"title":"Effect of Ketamine/Propofol Admixture on Peri-Induction Hemodynamics: A Systematic Review and Meta-Analysis.","authors":"Nathan J Smischney, Mohamed O Seisa, Allison S Morrow, Oscar J Ponce, Zhen Wang, Muayad Alzuabi, Katherine J Heise, Mohammad H Murad","doi":"10.1155/2020/9637412","DOIUrl":"10.1155/2020/9637412","url":null,"abstract":"<p><p>To evaluate the effectiveness of an admixture of ketamine and propofol on peri-induction hemodynamics during airway manipulation, we searched electronic databases of randomized controlled trials from January 1, 2000, to October 17, 2018. Trial screening, selection, and data extraction were done independently by two reviewers with outcomes pooled across included trials using the random-effects model. We included 10 randomized trials (722 patients, mean age of 53.99 years, 39.96% female). American Society of Anesthesiologists physical status was reported in 9 trials with classes I and II representing the majority. Ketamine/propofol admixture was associated with a nonsignificant increase in heart rate (weighted mean difference, 3.36 beats per minute (95% CI, -0.88, 7.60), <i>I</i> <sup>2</sup> = 88.6%), a statistically significant increase in systolic blood pressure (weighted mean difference, 9.67 mmHg (95% CI, 1.48, 17.86), <i>I</i> <sup>2</sup> = 87.2%), a nonsignificant increase in diastolic blood pressure (weighted mean difference, 2.18 mmHg (95% CI, -2.82, 7.19), <i>I</i> <sup>2</sup> = 73.1%), and a nonsignificant increase in mean arterial pressure (weighted mean difference, 3.28 mmHg (95% CI, -0.94, 7.49), <i>I</i> <sup>2</sup> = 69.9%) compared to other agents. The risk of bias was high and the certainty of evidence was low. In conclusion, among patients undergoing airway manipulation and needing sedation, the use of a ketamine/propofol admixture may be associated with better hemodynamics compared to nonketamine/propofol sedation. This trial is registered with CRD42019125725.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"9637412"},"PeriodicalIF":1.4,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37977065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Cognitive Aids: Results from a National Survey among Anaesthesia Providers in France and Canada. 认知辅助工具的使用:来自法国和加拿大麻醉提供者的全国调查结果。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-05-06 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1346051
Antonia Blanié, Matthieu Kurrek, Sophie Gorse, Dimitri Baudrier, Dan Benhamou
{"title":"Use of Cognitive Aids: Results from a National Survey among Anaesthesia Providers in France and Canada.","authors":"Antonia Blanié,&nbsp;Matthieu Kurrek,&nbsp;Sophie Gorse,&nbsp;Dimitri Baudrier,&nbsp;Dan Benhamou","doi":"10.1155/2020/1346051","DOIUrl":"https://doi.org/10.1155/2020/1346051","url":null,"abstract":"<p><strong>Introduction: </strong>The use of cognitive aids (CAs) during critical events is thought to be useful. However, whether CAs are known and used by French and Canadian anaesthesia providers is not clear.</p><p><strong>Methods: </strong>A survey was emailed to French and Canadian anaesthesia providers in 2017 through their respective national societies. It consisted of 23 questions about the participants' demographics and their knowledge, use, and impact of CAs. A second survey was sent to French simulation centres.</p><p><strong>Results: </strong>912 responses were recorded in France and 278 in Canada (overall response rate: 7% and 11%, respectively). Among the respondents, 700/899 in France (78%) versus 249/273 (91%) in Canada were familiar with the concept of cognitive dysfunction during a crisis and 501/893 (56%) in France versus 250/271 (92%) in Canada knew the concept of CAs. Amongst those respondents who knew about CAs, 189/492 (38%) in France versus 108/244 (44%) in Canada stated that they had already used a CA in real life and 225/493 (45%) in France versus 126/245 (51%) in Canada had received training in their use. Simulation was the principal modality for training in 150/225 (67%) of cases in France versus 47/126 (37%) in Canada. Among the 28/50 French simulation centres which responded (2018 January), 27 organised sessions in anaesthesia and 22 used CAs.</p><p><strong>Conclusion: </strong>CAs were better known in Canada than in France, but their actual use in real life was low in both countries. Simulation appears to play a potentially important role training anaesthesia providers in the use of CAs.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"1346051"},"PeriodicalIF":1.4,"publicationDate":"2020-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/1346051","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37977064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Retrospective Evaluation of Anesthetic Management in Cesarean Sections of Pregnant Women with Placental Anomaly. 胎盘异常孕妇剖宫产术麻醉处理的回顾性评价。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-04-30 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1358258
Aykut Urfalıoglu, Gözen Öksüz, Bora Bilal, Seyma Teksen, Feyza Calışır, Ömer Faruk Boran, Hafize Öksüz
{"title":"Retrospective Evaluation of Anesthetic Management in Cesarean Sections of Pregnant Women with Placental Anomaly.","authors":"Aykut Urfalıoglu,&nbsp;Gözen Öksüz,&nbsp;Bora Bilal,&nbsp;Seyma Teksen,&nbsp;Feyza Calışır,&nbsp;Ömer Faruk Boran,&nbsp;Hafize Öksüz","doi":"10.1155/2020/1358258","DOIUrl":"https://doi.org/10.1155/2020/1358258","url":null,"abstract":"<p><strong>Background: </strong>In this study, patients who underwent cesarean section and had placenta previa and placenta accreta were examined and compared in terms of haemorrhagic indicators and perioperative anesthetic management.</p><p><strong>Methods: </strong>A retrospective study was conducted in a university hospital in Kahramanmaras, Turkey. It included 95 pregnant women who had placental anomaly and underwent cesarean section between December 15, 2014, and February 15, 2016.</p><p><strong>Results: </strong>The pregnant women were divided into two groups: Group P (previa) (<i>n</i> = 67) and Group A (accreta) (<i>n</i> = 28). The types of anesthesia administered were general anesthesia (GA), which was administered to 50 patients (74.6%) in Group P and 27 patients (96.4%) in Group A, and spinal anesthesia (SA), which was administered to 17 patients (25.4%) in Group P and one patient (3.6%) in Group A.. The mean blood loss was 685.82 ± 262.82 in Group P and 1582.14 ± 790.71 in Group A, and the given amount of crystalloid was higher in Group A with an average of 1628.57 ± 728.19 ml. The use of erythrocyte and fresh frozen plasma solution was higher in Group A than Group P. Eleven patients were intubated and taken to the Intensive Care Unit (ICU) in Group A. Postoperative mechanical ventilation duration was significantly higher in Group A (75.14 ± 43.84 h) (<i>p</i> < 0.001). ICU stay was longer in Group A with 2.80 ± 1.13 days. (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>The intraoperative management and the availability of postoperative ICU conditions are important in placental anomalies cases. The communication between operation team with regard to the development of a standard protocol for these cases will be of great benefit in reducing morbidity and mortality.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"1358258"},"PeriodicalIF":1.4,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/1358258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37939347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A Review of Nonanesthetic Uses of Ketamine. 氯胺酮非麻醉用途综述。
IF 1.6
Anesthesiology Research and Practice Pub Date : 2020-04-01 eCollection Date: 2020-01-01 DOI: 10.1155/2020/5798285
Abby Pribish, Nicole Wood, Arun Kalava
{"title":"A Review of Nonanesthetic Uses of Ketamine.","authors":"Abby Pribish, Nicole Wood, Arun Kalava","doi":"10.1155/2020/5798285","DOIUrl":"10.1155/2020/5798285","url":null,"abstract":"<p><p>Ketamine, a nonselective NMDA receptor antagonist, is used widely in medicine as an anesthetic agent. However, ketamine's mechanisms of action lead to widespread physiological effects, some of which are now coming to the forefront of research for the treatment of diverse medical disorders. This paper aims at reviewing recent data on key nonanesthetic uses of ketamine in the current literature. MEDLINE, CINAHL, and Google Scholar databases were queried to find articles related to ketamine in the treatment of depression, pain syndromes including acute pain, chronic pain, and headache, neurologic applications including neuroprotection and seizures, and alcohol and substance use disorders. It can be concluded that ketamine has a potential role in the treatment of all of these conditions. However, research in this area is still in its early stages, and larger studies are required to evaluate ketamine's efficacy for nonanesthetic purposes in the general population.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"5798285"},"PeriodicalIF":1.6,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37849874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appropriate Blood Pressure in Cerebral Aneurysm Clipping for Prevention of Delayed Ischemic Neurologic Deficits. 脑动脉瘤夹闭术中适当血压预防迟发性缺血性神经功能缺损。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-04-01 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6539456
Cattleya Thongrong, Pornthep Kasemsiri, Pichayen Duangthongphon, Amnat Kitkhuandee
{"title":"Appropriate Blood Pressure in Cerebral Aneurysm Clipping for Prevention of Delayed Ischemic Neurologic Deficits.","authors":"Cattleya Thongrong,&nbsp;Pornthep Kasemsiri,&nbsp;Pichayen Duangthongphon,&nbsp;Amnat Kitkhuandee","doi":"10.1155/2020/6539456","DOIUrl":"https://doi.org/10.1155/2020/6539456","url":null,"abstract":"<p><strong>Background: </strong>Delayed ischemic neurologic deficit (DNID) is a problem after cerebral aneurysm clipping. Intraoperative hypotension seems to be indicated as a risk factor, but it remains a controversial issue with varying low-blood pressure levels accepted.</p><p><strong>Methods: </strong>A retrospective, hospital-based, case-control study was performed with patients who received general anesthesia for cerebral aneurysm clipping. 42 medical record charts were randomly selected and matched 1 : 2 (1 case with DNID : 2 controls without DNID) based on the type of general anesthetic techniques and severity of subarachnoid hemorrhage. The optimal cutoff points of hemodynamic response were calculated by the area under the curve.</p><p><strong>Results: </strong>Data suggested that the optimal cutoff points for lowest blood pressure for prevention of DNID should be systolic blood pressure (SBP) of 95 mmHg (sensitivity of 78.6%; specificity of 53.6%), diastolic blood pressure (DBP) of 50 mmHg (sensitivity of 71.4%; specificity of 67.9%), and mean arterial pressure (MAP) of 61.7 mmHg (sensitivity of 85.7%; specificity of 35.7%). Furthermore, the optimal cutoff point mean difference baseline blood pressure was recommended as Δ SBP of 36 mmHg (sensitivity of 85.7%; specificity of 60.7%), Δ DBP of 27 mmHg (sensitivity of 92.9%; specificity of 71.4%), and Δ MAP of 32 mmHg (sensitivity of 92.9%; specificity of 85.7%). No significant difference between DNID and non-DNID groups was found for end-tidal carbon dioxide (ETCO<sub>2</sub>) and has poor diagnostic value for predicting DNID.</p><p><strong>Conclusion: </strong>To prevent DNID, we recommend that optimal blood pressure should not be lower than 95 for SBP, 50 for DBP, and 61.7 mmHg for MAP. Additionally, we suggest that Δ SBP, Δ DBP, and Δ MAP should be less than 36, 27, and 32 mmHg, respectively.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"6539456"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/6539456","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37849873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Outcomes of the Extreme Elderly Undergoing Anaesthesia and Surgery amongst Southeast Asians. 东南亚极端老年人接受麻醉和手术的结果。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-03-30 eCollection Date: 2020-01-01 DOI: 10.1155/2020/4562528
Si Jia Lee, Oriana Ng, Sze Ying Thong
{"title":"Outcomes of the Extreme Elderly Undergoing Anaesthesia and Surgery amongst Southeast Asians.","authors":"Si Jia Lee,&nbsp;Oriana Ng,&nbsp;Sze Ying Thong","doi":"10.1155/2020/4562528","DOIUrl":"https://doi.org/10.1155/2020/4562528","url":null,"abstract":"<p><strong>Results: </strong>Sixty-two patients were identified. The mean age is 93.6 years. Majority were ASA 2 and ASA 3 patients. The most common type of surgery performed was orthopaedic, followed by vascular and urologic. Seven of the 62 patients required re-operations. Regional was the predominant anaesthetic technique employed, followed by general anaesthesia. Intraoperative hypotension was seen in 16 of the patients, all of whom recovered uneventfully. Hypothermia, desaturation, and hypertension were the top three complications observed in the recovery. Seventeen patients were admitted to a high-dependency facility postoperatively. The mean length of stay was 13.7 days. The 30-day mortality was 1.6 percent.</p><p><strong>Conclusions: </strong>We have provided a snapshot of very elderly patients coming for surgery. The results show that this group of elderly patients do well postoperatively with relatively low complication and 30-day mortality rates. The outcomes presented can be used as a guide for risk counseling in the perioperative period.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"4562528"},"PeriodicalIF":1.4,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/4562528","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37837522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Effect of Intraoperative Methadone Compared to Morphine on Postsurgical Pain: A Meta-Analysis of Randomized Controlled Trials. 术中美沙酮与吗啡对术后疼痛的影响:随机对照试验的荟萃分析。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-03-27 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6974321
Mark C Kendall, Lucas J Alves, Kristi Pence, Taif Mukhdomi, Daniel Croxford, Gildasio S De Oliveira
{"title":"The Effect of Intraoperative Methadone Compared to Morphine on Postsurgical Pain: A Meta-Analysis of Randomized Controlled Trials.","authors":"Mark C Kendall,&nbsp;Lucas J Alves,&nbsp;Kristi Pence,&nbsp;Taif Mukhdomi,&nbsp;Daniel Croxford,&nbsp;Gildasio S De Oliveira","doi":"10.1155/2020/6974321","DOIUrl":"https://doi.org/10.1155/2020/6974321","url":null,"abstract":"<p><strong>Methods: </strong>We performed a quantitative systematic review of randomized controlled trials in PubMed, Embase, Cochrane Library, and Google Scholar electronic databases. Meta-analysis was performed using the random effects model, weighted mean differences (WMD), standard deviation, 95% confidence intervals, and sample size. Methodological quality was evaluated using Cochrane Collaboration's tool.</p><p><strong>Results: </strong>Seven randomized controlled trials evaluating 337 patients across different surgical procedures were included. The aggregated effect of intraoperative methadone on postoperative opioid consumption did not reveal a significant effect, WMD (95% CI) of -0.51 (-1.79 to 0.76), (<i>P</i>=0.43) IV morphine equivalents. In contrast, the effect of methadone on postoperative pain demonstrated a significant effect in the postanesthesia care unit, WMD (95% CI) of -1.11 (-1.88 to -0.33), <i>P</i>=0.005, and at 24 hours, WMD (95% CI) of -1.35 (-2.03 to -0.67), <i>P</i> < 0.001.</p><p><strong>Conclusions: </strong>The use of intraoperative methadone reduces postoperative pain when compared to morphine. In addition, the beneficial effect of methadone on postoperative pain is not attributable to an increase in postsurgical opioid consumption. Our results suggest that intraoperative methadone may be a viable strategy to reduce acute pain in surgical patients.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2020 ","pages":"6974321"},"PeriodicalIF":1.4,"publicationDate":"2020-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/6974321","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37824978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Patient Complications after Interscalene Block: A Retrospective Comparison of Liposomal Bupivacaine to Nonliposomal Bupivacaine. 斜角肌间阻滞后的并发症:布比卡因脂质体与非脂质体的回顾性比较。
IF 1.4
Anesthesiology Research and Practice Pub Date : 2020-03-27 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6704303
Jacob L Hutchins, Jason Habeck, Zac Novaczyk, Richard Campbell, Christopher Creedon, Ellen Spartz, Michael Richter, Jeremy Wolter, Gaurav Suryawanshi, Alexander Kaizer, Aaron A Berg
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引用次数: 2
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