Annali di stomatologia最新文献

{"title":"<i>In vitro</i> resistance to fracture of two nickel-titanium rotary instruments made with different thermal treatments.","authors":"Gabriele Miccoli,&nbsp;Gianfranco Gaimari,&nbsp;Marco Seracchiani,&nbsp;Antonio Morese,&nbsp;Tatyana Khrenova,&nbsp;Dario Di Nardo","doi":"10.11138/ads/2017.8.2.059","DOIUrl":"https://doi.org/10.11138/ads/2017.8.2.059","url":null,"abstract":"<p><strong>Aim: </strong>Aim of the study was to evaluate effectiveness of different heat treatments in improving Ni-Ti endodontic rotary instruments' resistance to fracture.</p><p><strong>Methods: </strong>24 new NiTi instruments similar in length and shape: 12 M3 instruments, tip size 25 and .06 taper (United Dental, Shanghai, China), and 12 M3 Pro Gold instruments tip size 25 and .06 taper (United Dental, Shanghai, China), were tested in a 60° curved artificial root canal. Each group received a different heat treatment. Cycles to fracture were calculated for each instrument. Differences among groups were evaluated with an analysis of variance test (significance level was set at P<0.05.).</p><p><strong>Results: </strong>Statistical analysis found significant differences (p<0.0213) between groups. The M3 Pro Gold instruments were significantly more resistant to fatigue (mean values = 1012, SD +/- 77) than M3 instruments (mean values = 748, SD +/- 62). No statistically significant differences were found between fragments' lengths (p>0,05).</p><p><strong>Conclusions: </strong>An increased flexibility and the reduction of internal defects produced by heat treatments during or after manufacturing processes, may be responsible for improving resistance to cyclic fatigue and flexural stresses.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 2","pages":"53-58"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.2.059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35706978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of two different debonding techniques in orthodontic treatment.","authors":"Luca Piccoli,&nbsp;Guido Migliau,&nbsp;Laith Konstantinos Besharat,&nbsp;Stefano Di Carlo,&nbsp;Giorgio Pompa,&nbsp;Roberto Di Giorgio","doi":"10.11138/ads/2017.8.2.079","DOIUrl":"https://doi.org/10.11138/ads/2017.8.2.079","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this research is to investigate whether and how the adhesive bond failure site varied in relation to the material used for the orthodontic bonding and debonding technique applied.</p><p><strong>Materials and methods: </strong>Two different methods of orthodontic debonding were included in our survey; cutters for orthodontics and debonding plier. Three different materials for the adhesion of the bracket: composite light curing, self-curing composite and glass ionomer cement. The remaining amount of adhesive on the tooth surface is an important parameter that gives information on how the location of the posting site varied during the debonding. 60 dental elements, maxillary and mandibular, previously extracted for orthodontic reasons, as well as periodontal, were included in our research. We investigated a possible significant correlation between different variables (debonding technique and materials for membership) and the ARI index.</p><p><strong>Conclusions: </strong>The use of orthodontic cutters or debonding pliers does not affect the adhesive bond failure site and both techniques have a tendency to leave a significant amount of adhesive on the surface enamel. In the resin-reinforced glass ionomer cements, detachment occurs at the interface enamel-adhesive and this pattern of detachment increases the risk of the enamel damage during debonding. In both types of composite resins (photopolymerizable or self-curing), the detachment occurs at the interface bracketing adhesive. In this case the amount of remaining adhesive material on the tooth must be removed with further methods, which in addition, increase the risk of iatrogenic injury as well as the working hours.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 2","pages":"71-78"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.2.079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35707431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention of neurological injuries during mandibular third molar surgery: technical notes.","authors":"Gerardo La Monaca, Iole Vozza, Rita Giardino, Susanna Annibali, Nicola Pranno, Maria Paola Cristalli","doi":"10.11138/ads/2017.8.2.053","DOIUrl":"10.11138/ads/2017.8.2.053","url":null,"abstract":"<p><p>Surgery to the mandibular third molar is common, and injuries to the inferior alveolar nerve and the lingual nerve are well-recognized complications of this procedure. The aim of these technical notes is to describe operative measures for reducing neurological complications during mandibular third molar surgery. The following procedure should be used to prevent damage to the inferior alveolar nerve: a well-designed mucoperiosteal flap, to obtain appropriate access to the surgical area; a conservative ostectomy on the distal and distal-lingual side; tooth sectioning, to facilitate its removal by decreasing the retention zones; tooth dislocation in the path of withdrawal imposed by the curvature of the root apex; and careful socket debridement, when the roots of the extracted tooth are in intimate contact with the mandibular canal. To prevent injury to the lingual nerve, it is important (I) to assess the integrity of the mandibular inner cortex and exclude the presence of fenestration, which could cause the dislocation of the tooth or its fragment into the sublingual or submandibular space; (II) to avoid inappropriate or excessive dislocation proceedings, in order to prevent lingual cortex fracture; (III) to perform horizontal mesial-distal crown sectioning of the lingually inclined tooth; (IV) to protect the lingual flap with a retractor showing the cortical ridge; and (V) to pass the suture not too apically and from the inner side in a buccal-lingual direction in the retromolar area.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 2","pages":"45-52"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.2.053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35706982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An atypical case of craniometaphyseal dysplasia. Case report and surgical treatment.","authors":"Giorgio Novelli,&nbsp;Emanuela Ardito,&nbsp;Fabio Mazzoleni,&nbsp;Alberto Bozzetti,&nbsp;Davide Sozzi","doi":"10.11138/ads/2017.8.2.045","DOIUrl":"https://doi.org/10.11138/ads/2017.8.2.045","url":null,"abstract":"<p><strong>Introduction: </strong>Craniometaphyseal dysplasia is a rare hereditary bone disease presenting metaphyseal widening of the tubular bones, sclerosis of craniofacial bones and bony overgrowth of the facial and skull bones. Craniometaphyseal dysplasia occurs in an autosomal dominant (AD) and an autosomal recessive (AR) form.</p><p><strong>Case report: </strong>We present a 32-year-old patient arrived at our unit in May 2009. His main discomfort was a major limitation of the mouth opening, in the context of a craniofacial deformity. Relying on patient's medical history and the performed diagnostic tests, the diagnosis of craniometaphyseal dysplasia was made.</p><p><strong>Conclusion: </strong>After careful evaluation of the clinical case, in accordance with the requirements of the patient, we opted for a surgical treatment aimed at correction of functional limitation of temporomandibular joint and aesthetic improvement of the facial bones. The stability of the clinical results led us to suggest and to undertake the surgical path, also due to the lack of safe and consolidated non-surgical treatments for the specific case.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 2","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"2017-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749377/pdf/89-94.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35706983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between three glass fiber post cementation techniques.","authors":"Guido Migliau,&nbsp;Luca Piccoli,&nbsp;Stefano Di Carlo,&nbsp;Giorgio Pompa,&nbsp;Laith Konstantinos Besharat,&nbsp;Marco Dolci","doi":"10.11138/ads/2017.8.1.029","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.029","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this experimental study was to compare the traditional cement systems with those of the latest generation, to assess if indeed these could represent of viable substitutes in the cementation of indirect restorations, and in the specific case of endodontic posts.</p><p><strong>Methods: </strong>The assessment of the validity of the cementing methods was performed according to the test of the push-out, conducted on sections obtained from the roots of treated teeth. The samples were divided into three groups. Group A (10 samples): etching for 30 seconds with 37% orthophosphoric acid (Superlux-Thixo-etch-DMG) combined with a dual-curing adhesive system (LuxaBond-Total Etch-DMG), dual-cured resin-composite cement (LuxaCore-DMG) and glass fiber posts (LuxaPost-DMG). Group B (10 samples): self-adhesive resin cement (Breeze-Pentron Clinical) and glass fiber posts (LuxaPost-DMG). Group C (10 samples): 3 steps light-curing, self-etching, self-conditioning bonding agent (Contax-Total-etch-DMG), dual-cured resin-composite cement (LuxaCore-DMG) and glass fiber posts (LuxaPost-DMG). The survey was conducted by examining the breaking resistance of the post-cement-tooth complex, subjected to a mechanical force. Statistical analysis was performed using SPSS Inc. ver. 13.0, Chicago, IL, USA.</p><p><strong>Results: </strong>Group A values of bond strenth ranged from a minimum of 10.14 Mpa to a maximum value of 14.73 Mpa with a mean value of 12.58 Mpa. In Group B the highest value of bond strength was 6.54 Mpa and the minimum 5.55 Mpa. The mean value of the bond strength for the entire group was 6.58 Mpa. In Group C the highest bond strength was 6.59 Mpa whereas the lowest bond strength was 4.84 Mpa. Mean value of the bond strength of Group C was calculated at 5.7 Mpa.</p><p><strong>Conclusions: </strong>Etching with orthophosphoric acid combined with a dual-curing adhesive system and a dual-cured resin-composite cement was the technique that guaranteed the highest bond strength. Lowest bond strength values were obtained when dual self-adhesive cement was used.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.1.029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification review of dental adhesive systems: from the IV generation to the universal type.","authors":"Eshrak Sofan,&nbsp;Afrah Sofan,&nbsp;Gaspare Palaia,&nbsp;Gianluca Tenore,&nbsp;Umberto Romeo,&nbsp;Guido Migliau","doi":"10.11138/ads/2017.8.1.001","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.001","url":null,"abstract":"<p><p>Adhesive dentistry has undergone great progress in the last decades. In light of minimal-invasive dentistry, this new approach promotes a more conservative cavity design, which relies on the effectiveness of current enamel-dentine adhesives. Adhesive dentistry began in 1955 by Buonocore on the benefits of acid etching. With changing technologies, dental adhesives have evolved from no-etch to total-etch (4^th and 5^th generation) to self-etch (6^th, 7^th and 8^th generation) systems. Currently, bonding to dental substrates is based on three different strategies: 1) etch-and-rinse, 2) self-etch and 3) resin-modified glass-ionomer approach as possessing the unique properties of self-adherence to the tooth tissue. More recently, a new family of dentin adhesives has been introduced (universal or multi-mode adhesives), which may be used either as etch-and-rinse or as self-etch adhesives. The purpose of this article is to review the literature on the current knowledge for each adhesive system according to their classification that have been advocated by many authorities in most operative/restorative procedures. As noted by several valuable studies that have contributed to understanding of bonding to various substrates helps clinicians to choose the appropriate dentin bonding agents for optimal clinical outcomes.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.1.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of different kinds of beers on the surface roughness of glazed and polished methacrylate and Silorane-based composites: a 1-month study.","authors":"Ugur Erdemir,&nbsp;Murat Tiryaki,&nbsp;Gunce Saygi,&nbsp;Taner Yücel,&nbsp;Sevda Ozel Yildiz,&nbsp;Esra Yıldız","doi":"10.11138/ads/2017.8.1.023","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.023","url":null,"abstract":"<p><strong>Background: </strong>The aim of this <i>in vitro</i> study was to evaluate the effect of different kind of beers on the surface roughness of glazed and polished methacrylate- and Silorane-based resin composites after different immersion periods.</p><p><strong>Methods: </strong>Methacrylate-based resin composites (Tetric N-Ceram, Ceram-X) and a Silorane-based resin composite (Filtek Silorane) were tested in the study. A total of 126 specimens (n=42 for each composite) were fabricated using a cylindrical custom metal mould. Surface roughness measurement was performed using a profilometer at baseline and after a 1-week and 1-month immersion in different kind of beers or distilled water. The results were analysed using repeated measure ANOVA and Tukey's HSD test (α=0.05).</p><p><strong>Results: </strong>Repeated measure ANOVA results revealed that immersion period was a significant factor in the surface roughness of the tested specimens (p<0.001). The lowest surface roughness values were obtained with the specimens' polished Optidisc+BisCover LV. Regardless of the polishing systems used, Tetric N-Ceram showed the statistically lowest surface roughness values (p<0.05), whereas Filtek Silorane showed the highest surface roughness (p<0.001).</p><p><strong>Conclusion: </strong>The surface roughness values of the tested resin composites were affected by the polishing procedure used, the exposure time in the solutions and the type of composite resin.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507163/pdf/23-28.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive orthodontics: elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta.","authors":"Gaetano Ierardo,&nbsp;Valeria Luzzi,&nbsp;Giuliana Nardacci,&nbsp;Iole Vozza,&nbsp;Antonella Polimeni","doi":"10.11138/ads/2017.8.1.034","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.034","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the study was to report the use of an elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta, second class malocclusion, deep bite and lower arch crowding from the deciduous dentition to permanent one.</p><p><strong>Case report: </strong>At first, the 5-year-old patient was treated with an elastodontic device known as \"Nite-Guide\". When the patient was 7 years old, during her first permanent molars and incisors eruption and after optimal house-practices, an Occlus-o-Guide Series G was placed at night and on daylight (two hours a day) performing exercises aimed to activate facial muscles and facilitate the deep bite reopening. At 9 years of age, with totally deep bite resolution, she used the Occluso-Guide only at night to hold down previous results and follow patient's dental growth. At 11 years of age, after successful teeth switching, we prescribed an Occlus-o-Guide Series N, which is functional for permanent dentition and guaranteed an eruptive guide for last dental elements.</p><p><strong>Conclusions: </strong>This clinic case could be considered an example of approach for all those patients with systemic and/or dental diseases that do not allow adequate dental retention, which is necessary for most orthodontic appliances; elastodontic devices do not require adequate dental retention and define a minimum intervention on the surfaces of the teeth.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507165/pdf/34-38.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular bone regeneration after bone slat technique.","authors":"Salvatore D'Amato,&nbsp;Gianpaolo Tartaro,&nbsp;Angelo Itro,&nbsp;Mario Santagata","doi":"10.11138/ads/2017.8.1.039","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.039","url":null,"abstract":"<p><strong>Background: </strong>The reconstruction of alveolar ridges for implant placement is still a challenging surgical procedure, especially in the case of extensive vertical and horizontal bone atrophy.</p><p><strong>Objective: </strong>The objective of the present study was to evaluate the quantity and quality of newly regenerated bone; clinically by means of direct clinical measuring, ridges augmented by autogenous cortical bone associated with autogenous particulate bone graft in the posterior lower jaw defect.</p><p><strong>Methods: </strong>For the preliminary study, a bone defects in partially edentulous in patient aged 52 years were selected to receive horizontal ridge augumentation prior autolougous bone block and particulate graft. The donor site was the ramus of the same side. Prior the clinical evaluation, periapical X-ray and the cone beam computerized tomography (CBCT) was observed the quality, quantity and the stability the soft and hard tissue healing process, final result and the outcome.</p><p><strong>Result: </strong>The bone augmentation achieved with this technique created the ideal bone volume of hard and soft tissue, in quantity and quality, for placement of implants.</p><p><strong>Conclusion: </strong>The surgical technique was found to be easy in terms of technique and surgical trauma.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.1.039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic technical quality of root canal treatment performed by a new rotary single-file system.","authors":"Marco Colombo,&nbsp;Cristina Bassi,&nbsp;Riccardo Beltrami,&nbsp;Paolo Vigorelli,&nbsp;Antonio Spinelli,&nbsp;Andrea Cavada,&nbsp;Alberto Dagna,&nbsp;Marco Chiesa,&nbsp;Claudio Poggio","doi":"10.11138/ads/2017.8.1.018","DOIUrl":"https://doi.org/10.11138/ads/2017.8.1.018","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present study was to evaluate radiographically the technical quality of root canal filling performed by postgraduate students with a new single-file Nickel-Titanium System (F6 Skytaper Komet) in clinical practice.</p><p><strong>Methods: </strong>Records of 74 patients who had received endodontic treatment by postgraduate students at the School of Dentistry, Faculty of Medicine, University of Pavia in the period between September 2015 and April 2016 were collected and examined: the final sample consisted 114 teeth and 204 root canals. The quality of endodontic treatment was evaluated by examining the length of the filling in relation to the radiographic apex, the density of the obturation according to the presence of voids and the taper of root canal filling. Chi-squared analysis was used to determine statistically significant differences between the technical quality of root fillings according to tooth's type, position and curvature.</p><p><strong>Results: </strong>The results showed that 75,49%, 82,84% and 90,69% of root filled canals had adequate length, density and taper respectively.</p><p><strong>Conclusions: </strong>Overall, the technical quality of root canal fillings performed by postgraduates students was acceptable in 60,78% of the cases.</p>","PeriodicalId":78041,"journal":{"name":"Annali di stomatologia","volume":"8 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11138/ads/2017.8.1.018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35192124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}