Anesthesia & Analgesia最新文献

{"title":"Ketamine and Traumatic Memory After Intensive Care Unit Discharge: Patient Population and Sedation Concerns.","authors":"Matthieu Legrand,Jean-Michel Constantin,Lisa Burry,Romain Sonneville","doi":"10.1213/ane.0000000000007643","DOIUrl":"https://doi.org/10.1213/ane.0000000000007643","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"281 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep versus Moderate Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function: A Randomized Controlled Trial.","authors":"Veerle Bijkerk,Lotte M C Jacobs,Wim H C Rijnen,Christiaan Keijzer,Michiel C Warlé,Jetze Visser","doi":"10.1213/ane.0000000000007639","DOIUrl":"https://doi.org/10.1213/ane.0000000000007639","url":null,"abstract":"BACKGROUNDDeep neuromuscular blockade (NMB) enhances surgical working conditions in laparoscopic surgery. Whether this accounts for nonlaparoscopic surgery is not known. Additionally, the effect on clinical and patient-reported outcomes remains debated. In this study, the effect of deep NMB compared to moderate NMB during total hip arthroplasty (THA) on quality of recovery and postoperative inflammation is investigated.METHODSThis single-center randomized controlled blinded trial comprised 100 patients undergoing THA treated with deep NMB (posttetanic count 1-2) or moderate NMB (train-of-four 1-2). Continuous or bolus administration of rocuronium was used. The primary end point was quality of recovery on postoperative day 1 (POD1), measured by the Quality of Recovery-40 (QoR-40) questionnaire. The secondary end points were innate immune function and pain scores on POD1, measured by ex vivo production capacity of tumor necrosis factor (TNF) and interleukin (IL)-1β on whole blood stimulation with lipopolysaccharide and postoperative pain as rated by the numeric rating scale.RESULTSThere was no difference in QoR-40 score on POD1 (mean difference -4.1, 95% confidence interval -10.9 to 2.8, P = .241). On POD 1, there was no difference in ex vivo production capacity of TNF (moderate NMB median [quartiles] 890 [532-1605] pg/mL, deep NMB 1113 [651-1716] pg/mL, P = .34, Mann-Whitney U test, median difference -125, 95% confidence interval [CI], -440 to 155) and IL-1β (moderate NMB 1148 [545-1970] pg/mL, deep NMB median 1386 [826-1940] pg/mL, P = .36, median difference [MD] -135, 95% CI, -470 to 191) on lipopolysaccharide stimulation. On POD1, there was no statistically significant difference in pain scores at rest (MD 1.10, 99.6% CI, -0.53 to 2.74, P = .049) and on movement (MD 0.94, 99.6% CI, -0.63 to 2.50, P = .080).CONCLUSIONSNo evidence was found for a beneficial effect of deep NMB compared to moderate NMB in THA regarding quality of recovery or postoperative inflammation.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote Continuous Vital Sign Monitoring of Scoliosis Surgery Patients on General Wards: A Cost-Effectiveness Analysis.","authors":"Kevin M Trentino,Mohammad E Hoque,Adam Lloyd,Laura Trentino,Rinaldo Ienco,Kevin Murray,Tim Bowles,Sheldon Wulff,Jonathon Burcham,Aleesha Thompson,Grant Waterer","doi":"10.1213/ane.0000000000007655","DOIUrl":"https://doi.org/10.1213/ane.0000000000007655","url":null,"abstract":"BACKGROUNDScoliosis surgery patients often require continuous postoperative monitoring in intensive care (ICU) or high-dependency units (HDU). We implemented a 24-hour remote continuous monitoring service for high-risk inpatients (HIVE) to allow monitoring in general wards. This study aimed to evaluate the cost-effectiveness of the HIVE service.METHODSWe compared scoliosis surgery patients admitted pre- and postimplementation of the HIVE service and applied multivariable regression to adjust for differences in baseline characteristics. The primary outcome was incremental cost per ICU hour avoided.RESULTSWe compared 155 patients admitted postimplementation to 133 admitted preimplementation. In the adjusted analysis, the post-HIVE implementation period avoided 27.1 hours in ICU and reduced overall health care costs by AU$2682 (US$2164) per patient, compared with preimplementation. There were no statistically significant differences in hospital length of stay (rate ratio [RR], 1.01; 95% confidence interval [CI], 0.93-1.11; P = .785), emergency readmissions (odds ratio [OR], 0.93; 95% CI, 0.44-1.99; P = .854), or hospital-acquired complications (OR, 0.68; 95% CI, 0.27-1.66; P = .393).CONCLUSIONSIn scoliosis surgery, the implementation of a remote continuous inpatient monitoring service reduced inpatient costs and hours in ICU. In this group of patients, the HIVE service provides economic evidence of the cost-effectiveness of remote monitoring.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"677 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketamine and Traumatic Memory After Intensive Care Unit Discharge: Limitation of Opioid-Only Analgesia.","authors":"Fu-Shan Xue,Dan-Feng Wang,Xiao-Chun Zheng","doi":"10.1213/ane.0000000000007642","DOIUrl":"https://doi.org/10.1213/ane.0000000000007642","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"677 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Decision-Making and Process Complications During Difficult Airway Management.","authors":"Srikiran Ramarapu,Brayden Rucker","doi":"10.1213/ane.0000000000007640","DOIUrl":"https://doi.org/10.1213/ane.0000000000007640","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Institutional Validation of Quantra-Guided Bleeding Algorithm in Adult Liver Transplant Recipients.","authors":"Katherine T Forkin,Raeshun T Glover,Jenna Khan","doi":"10.1213/ane.0000000000007665","DOIUrl":"https://doi.org/10.1213/ane.0000000000007665","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Complications of Rocuronium versus Cisatracurium: Recurarization and the Cost of Assumed Safety.","authors":"Yu-Ting Lin,Ying-Kuan Chen,Shu-Yueh Cheng,Ming-Hui Hung","doi":"10.1213/ane.0000000000007659","DOIUrl":"https://doi.org/10.1213/ane.0000000000007659","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Absence of Neuromuscular Monitoring Limits Interpretation of Adverse Outcome Comparisons.","authors":"Hugo Carvalho,Lieselot Geerts","doi":"10.1213/ane.0000000000007661","DOIUrl":"https://doi.org/10.1213/ane.0000000000007661","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibrinogen Concentrate for Neonatal Cardiac Surgery.","authors":"","doi":"10.1213/ane.0000000000007657","DOIUrl":"https://doi.org/10.1213/ane.0000000000007657","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"190 6 1","pages":"239"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144629973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erector Spinae Catheters and Celiac Plexus Block for Analgesia After Total Pancreatectomy With Islet Autotransplantation: A Retrospective Feasibility Study.","authors":"Hana Mahmoud,Michael Adams,Cheryl Hartzell,Qing Duan,Lili Ding,Michelle Goetz,Juan Gurria,Vidya Chidambaran","doi":"10.1213/ane.0000000000007645","DOIUrl":"https://doi.org/10.1213/ane.0000000000007645","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144603788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}