Anesthesia & Analgesia最新文献

{"title":"Setting Priorities for African Postoperative Pain Research Through an International Delphi Process.","authors":"Gebrehiwot Asfaw,Tadesse B Melkie,Ananya A Shiferaw,Timothy M Mwiti,Gaston Nyirigira,Francois Retief,Alfa A Mikailu,Amos Zacharia,Ensa Jarju,Esubalew Lakew,Isabella Epiu,Kissoon Vishaal,Lynda Abed,Mequanent Yimer,Mubarak Mohamed,Oluwayemisi E Ekor,Prudence Bukuru,Robert Djagbletey,Amany E Ayad,Patrice Forget,Endale G Gebremedhn","doi":"10.1213/ane.0000000000007689","DOIUrl":"https://doi.org/10.1213/ane.0000000000007689","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Overweight and Obese Patients: A Simon 2-Stage Trial.","authors":"Mingxia Xu,Saiheng Xiang,Yun Ma,Lijuan Hu,Yueying Zheng,Diansan Su","doi":"10.1213/ane.0000000000007690","DOIUrl":"https://doi.org/10.1213/ane.0000000000007690","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging Time-Driven Activity-Based Costing to Benchmark Two Distinct Telehealth Anesthesia Preoperative Evaluation Processes During Integration of Two Hospitals.","authors":"Katherine A Rowe,Sashini K Godage,Annette A Wang,Sarah Ahmed,Kristin C Raymond,Amanda S Xi,Robert S Kaplan,Angela M Bader,David L Hepner","doi":"10.1213/ane.0000000000007683","DOIUrl":"https://doi.org/10.1213/ane.0000000000007683","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Financial Implications of Methadone Use in Cardiothoracic Surgery: A Post Hoc Analysis of a Retrospective Cohort.","authors":"Brennan A Hand,Ruchita Dholakia,Bradford B Smith,Bijan J Borah,Alyssa B Chapital,Adam J Milam","doi":"10.1213/ane.0000000000007684","DOIUrl":"https://doi.org/10.1213/ane.0000000000007684","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Education and Training in Perioperative Medicine: Current Versus Ideal Future State.","authors":"David L Hepner,Avital Y O'Glasser,Thomas R Vetter","doi":"10.1213/ane.0000000000007677","DOIUrl":"https://doi.org/10.1213/ane.0000000000007677","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Camera-Based Photoplethysmography for Measuring Heartbeat Intervals During General Anesthesia.","authors":"Hui-Hsuan Ke,Chien-Kun Ting,Yi-Ming Huang,Jui-Chun Hung,Pei-Yu Lai,Chang-Xing Shih,Hong-Ren Su,Wen-Chuan Kuo","doi":"10.1213/ane.0000000000007635","DOIUrl":"https://doi.org/10.1213/ane.0000000000007635","url":null,"abstract":"BACKGROUNDPhotoplethysmography has been used to assess vital signs since the late 19th century. Recently, camera-based photoplethysmography systems have gained attention due to their noninvasive nature. However, challenges such as low perfusion, motion artifacts, and ambient light interference limit their use during surgical anesthesia. This study evaluated the efficacy of a camera-based system (FaCare) compared with that of a conventional contact monitor (GE HealthCare CARESCAPE B850 patient monitor) in measuring heartbeat intervals during various stages of surgical anesthesia.METHODSThirty patients undergoing video-assisted thoracic surgery were included. Data were collected using a webcam and FaCare software at 4 stages: preanesthesia, postanesthesia, postanesthesia with a shadowless lamp, and postsurgery. Six remote photoplethysmography techniques using artificial intelligence algorithms processed the data.RESULTSThe results demonstrated a high level of agreement between the FaCare and GE HealthCare monitor. Pearson correlation analysis, Bland-Altman plots, and Welch's t test indicated that 88.1% of the heart rate correlation coefficients between the 2 devices were >0.8. Furthermore, their heartbeat interval measurements showed strong agreement in the Bland-Altman plots. FaCare showed comparable functionality, offering a noninvasive alternative suitable for operating rooms.CONCLUSIONSThis study evaluated the FaCare camera-based photoplethysmography system, integrating 6 remote photoplethysmography techniques with artificial intelligence algorithms, and compared it to a conventional contact monitor for measuring heartbeat intervals during surgical anesthesia. The results showed strong consistency between FaCare and the GE contact monitor across different anesthesia stages. These findings indicate that the noninvasive FaCare system reduces infection risks and improves patient comfort. Future research is recommended to optimize artificial intelligence algorithms, data synchronization, and sampling frequency to enhance its clinical application.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Damage-Associated Molecular Patterns in Perioperative Neurocognitive Disorders: A Narrative Review.","authors":"Wiriya Maisat,Koichi Yuki","doi":"10.1213/ane.0000000000007682","DOIUrl":"https://doi.org/10.1213/ane.0000000000007682","url":null,"abstract":"Perioperative neurocognitive disorders (PND), such as postoperative delirium (POD) and cognitive dysfunction (POCD), frequently affect older surgical patients and significantly impair postoperative quality of life. During surgical procedures, damage-associated molecular patterns (DAMPs) such as high-mobility group box 1 (HMGB1), mitochondrial DNA, and S100 proteins are released from injured cells and implicated in the pathogenesis of PND. These molecules activate innate immune pathways through pattern recognition receptors (PRRs) such as toll-like receptors (TLRs) and receptors for advanced glycation end products (RAGE). The systemic inflammatory response potentially compromises blood-brain barrier integrity, allowing peripheral immune cells to infiltrate the central nervous system. The resulting neuroinflammation disrupts synaptic function and neuronal connectivity, leading to cognitive impairments. Sustained activation of immune pathways creates a feedback loop where proinflammatory cytokines (eg, IL-1β and TNF-α) amplify DAMP release and immune activation, perpetuating chronic inflammation and cognitive dysfunction. Therapeutic strategies targeting DAMP-mediated pathways, such as glycyrrhizin (an HMGB1 inhibitor), dexmedetomidine (an anti-inflammatory anesthetic), and TLR4 inhibitors (eg, TAK-242), have shown promise in reducing neuroinflammation and protecting cognitive function in preclinical models. However, clinical translation requires validated biomarkers and further trials to ensure their safety and efficacy. This review offers a focused perspective on DAMP-specific mechanisms and emerging therapeutic interventions that modulate these pathways. By contributing to the current understanding of DAMPs in the context of PND, this work supports future research efforts aimed at developing biomarkers and targeted interventions to help mitigate postoperative neurocognitive complications in surgical patients.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"730 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Augmented Reality in Airway Management: A Scoping Review.","authors":"Andrew Hart,Matthew Zemel,Laurence Henson,Lynly Beard,Vivek Arora","doi":"10.1213/ane.0000000000007633","DOIUrl":"https://doi.org/10.1213/ane.0000000000007633","url":null,"abstract":"Augmented reality, which overlays virtual information onto the physical environment, is an emerging technology in health care with promising applications in education, diagnostics, and procedural support. Its use in airway management-an essential aspect of anesthesiology and critical care-remains underexplored. This scoping review evaluates the current literature on augmented reality in airway management, with the aim of identifying its benefits, limitations, and future potential. A systematic literature search was conducted using PubMed, Embase, and IEEE databases, after PRISMA-ScR guidelines. Studies were included if they focused on augmented reality-assisted airway training or procedures and excluded if they centered on virtual reality or lacked procedural relevance. Ten studies met inclusion criteria, including 8 observational studies and 2 randomized controlled trials. Most utilized head-mounted displays to support simulation-based training or procedural guidance across pediatric and adult populations. Outcomes assessed included objective measures-such as intubation success, timing, and procedural accuracy-and subjective metrics like user confidence, perceived usability, and educational value. Results varied across studies. Several reported enhanced anatomical visualization, improved procedural success, and increased realism in training. One randomized controlled trial demonstrated higher intubation success rates and reduced procedure times when augmented reality-assisted video laryngoscopy was compared to standard methods. Another randomized controlled trial using a head-mounted display to deliver a procedural checklist found greater checklist adherence but also longer intubation times. Subjective feedback from participants noted challenges including device complexity, learning curve, and equipment limitations. Despite these encouraging findings, the current evidence base is limited by small sample sizes, variability in study design, and a lack of standardized evaluation protocols. Importantly, no study directly assessed the safety profile of augmented reality in airway management or its impact on patient-centered outcomes. In conclusion, augmented reality has the potential to improve anatomical understanding, procedural accuracy, and educational engagement in airway management. However, its integration into clinical practice is still in early stages. More rigorous, large-scale clinical trials are needed to determine its efficacy, optimize usability, and clarify its role in enhancing patient safety and provider training in anesthesiology and critical care.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sagittal Computed Tomography Imaging May Estimate Loss of Resistance Depth During Thoracic Epidural Placement: A Retrospective Study.","authors":"Ammar Siddiqui,Iwan Sofjan,Hasit Mehta,Irim Salik,Gabriel Rodriguez,Leena Mathew, ","doi":"10.1213/ane.0000000000007681","DOIUrl":"https://doi.org/10.1213/ane.0000000000007681","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Personalized Body-Worn Alcohol Dispenser, Without Practitioner Feedback, on Bacterial Transmission, Hourly Hand Decontamination Events, and Practitioner Hand Contamination: A Multicenter Randomized Controlled Study.","authors":"Andrew J Pugely,Franklin Dexter,Brandon M Togioka,Colby Simmons,Michelle C Parra,Jonathan E Charnin,Matthew D Koff,Jeremiah R Brown,Brendan T Wanta,Patrick Fernandez Md,Randy W Loftus","doi":"10.1213/ane.0000000000007671","DOIUrl":"https://doi.org/10.1213/ane.0000000000007671","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144777836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}