Jade Perdereau, Thibaut Chamoux, Etienne Gayat, Arthur Le Gall, Fabrice Vallée, Jérôme Cartailler, Jona Joachim
{"title":"Blood Pressure Estimation Using Explainable Deep-Learning Models Based on Photoplethysmography","authors":"Jade Perdereau, Thibaut Chamoux, Etienne Gayat, Arthur Le Gall, Fabrice Vallée, Jérôme Cartailler, Jona Joachim","doi":"10.1213/ane.0000000000007295","DOIUrl":"https://doi.org/10.1213/ane.0000000000007295","url":null,"abstract":". We developed a deep-learning model that reconstructs continuous mean arterial pressure (MAP) using the photoplethysmograhy (PPG) signal and compared it to the arterial line gold standard. METHODS: We analyzed high-frequency PPG signals from 117 patients in neuroradiology and digestive surgery with a median of 2201 (interquartile range [IQR], 788–4775) measurements per patient. We compared models with different combinations of convolutional and recurrent layers using as inputs for our neural network high-frequency PPG and derived features including dicrotic notch relative amplitude, perfusion index, and heart rate. Mean absolute error (MAE) was used as performance metrics. Explainability of the deep-learning model was reconstructed with Grad-CAM, a visualization technique using saliency maps to highlight the parts of an input that are significant for a deep-learning model decision-making process. RESULTS: An MAP baseline model, which consisted only of standard cuff measures, reached an MAE of 6.1 (± 14.5) mm Hg. In contrast, the deep-learning model achieved an MAE of 3.5 (± 4.4) mm Hg on the external test set (a 42.6% improvement). This model also achieved the narrowest confidence intervals and met international standards used within the community (grade A). The saliency map revealed that the deep-learning model primarily extracts information near the dicrotic notch region. CONCLUSIONS: Our deep-learning model noninvasively estimates arterial pressure with high accuracy. This model may show potential as a decision-support tool in operating-room settings, particularly in scenarios where invasive blood pressure monitoring is unavailable....","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142832269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alex Macario, Mohammed M. Minhaj, Mark T. Keegan, Ann E. Harman
{"title":"Large Language Models and the American Board of Anesthesiology Examination","authors":"Alex Macario, Mohammed M. Minhaj, Mark T. Keegan, Ann E. Harman","doi":"10.1213/ane.0000000000007322","DOIUrl":"https://doi.org/10.1213/ane.0000000000007322","url":null,"abstract":"An abstract is unavailable.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142831964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Additive and Multiplicative Interactions in Factorial Randomized Trials: What, Why, and How?","authors":"Edward J. Mascha","doi":"10.1213/ane.0000000000007175","DOIUrl":"https://doi.org/10.1213/ane.0000000000007175","url":null,"abstract":"An abstract is unavailable.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142831971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Challenge of Unexplained Practice Variability","authors":"Avery Tung","doi":"10.1213/ane.0000000000007059","DOIUrl":"https://doi.org/10.1213/ane.0000000000007059","url":null,"abstract":"An abstract is unavailable.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142831973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul P. Potnuru, Srikar Jonna, Barbara Orlando, Omonele O. Nwokolo
{"title":"Racial and Ethnic Disparities in Epidural Blood Patch Utilization Among Obstetric Patients in the United States: A Nationwide Analysis, 2016–2020","authors":"Paul P. Potnuru, Srikar Jonna, Barbara Orlando, Omonele O. Nwokolo","doi":"10.1213/ane.0000000000006754","DOIUrl":"https://doi.org/10.1213/ane.0000000000006754","url":null,"abstract":"itating neuraxial anesthesia complication associated with significant maternal morbidity if undertreated. In this nationwide study, we examine the racial and ethnic disparities in the inpatient utilization of EBP after obstetric PDPH in the United States. METHODS: In this retrospective observational study, we used the National Inpatient Sample, a nationally representative database of discharge records for inpatient admissions in the United States, from 2016 to 2020. We analyzed delivery hospitalizations of women of childbearing age (15–49 years) diagnosed with PDPH. Adjusting for maternal and hospitalization characteristics as confounders, we used a multilevel mixed-effects logistic regression model to compare the rates of EBP utilization by race and ethnicity. Secondarily, among hospitalizations with an EBP, we examined the association between race and ethnicity and the timing of the EBP procedure. RESULTS: We analyzed 49,300 delivery hospitalizations with a diagnosis of PDPH. An EBP was performed in 24,075 (48.8%; 95% confidence interval [CI], 47.8%–49.9%) of these hospitalizations. EBP was performed in 52.7% (95% CI, 51.3%–54.1%) of White non-Hispanic patients with PDPH. Compared to White non-Hispanic patients, Black non-Hispanic (adjusted odds ratio [aOR] = 0.69; 99% CI, 0.56–0.84), Hispanic (aOR = 0.80, 99% CI, 0.68–0.95), and Asian or Pacific Islander patients (aOR = 0.74, 99% CI, 0.58–0.96) were less likely to receive an EBP. The median (interquartile range [IQR]) time to perform an EBP was 2 (1–3) days after admission, with 90% of EBP procedures completed within 4 days of admission. There was no significant association between race and ethnicity and the timing of EBP placement. CONCLUSIONS: In this nationwide analysis of delivery hospitalizations from 2016 to 2020 in the United States with a diagnosis of PDPH, we identified racial and ethnic disparities in the utilization of EBP. Minoritized patients identified as Black non-Hispanic, Hispanic, or Asian or Pacific Islander were less likely to receive an EBP for the treatment of PDPH compared to White non-Hispanic patients. Suboptimal treatment of PDPH may be associated with adverse long-term outcomes such as postpartum depression, posttraumatic stress disorder, and chronic headaches. Racial and ethnic disparities in EBP utilization should be further investigated to ensure equitable health care delivery....","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"It Depends on Whom You Ask: Perceptions of Dignity-Related Distress Among Critically Ill Patients and Families","authors":"Shahla Siddiqui","doi":"10.1213/ane.0000000000007077","DOIUrl":"https://doi.org/10.1213/ane.0000000000007077","url":null,"abstract":"An abstract is unavailable.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"250 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pauline B. Wake, Patricia Livingston, Ekta Rai, Robert J. McDougall
{"title":"The World Federation of Societies of Anaesthesiologists’ Fellowship Programs: Past, Present, and Future","authors":"Pauline B. Wake, Patricia Livingston, Ekta Rai, Robert J. McDougall","doi":"10.1213/ane.0000000000006984","DOIUrl":"https://doi.org/10.1213/ane.0000000000006984","url":null,"abstract":"An abstract is unavailable.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}