Analytical Letters最新文献_第4页

One-Pot Electrochemical Biosensor Combining a Magnetite/Gold Modified Electrode and the Strand Displacement Reaction for Sensitive Determination of Escherichia coli 磁铁矿/金修饰电极与链置换反应相结合的一锅式电化学生物传感器用于大肠杆菌的灵敏检测

4区化学

Analytical Letters Pub Date : 2025-05-29 DOI: 10.1080/00032719.2025.2509638

Yu Liao, Yuxin Xue, Haoran Wang, Zhiying Gao, Chao Shi, Cuiping Ma, Yong Li, Yaofang Fan

引用次数: 1

Quantitation of Arsenic in biological matrices: Use of Sector Field Inductively Coupled Plasma-Mass Spectrometry for Improved Accuracy and Specificity. 生物基质中砷的定量：使用扇形场电感耦合等离子体质谱法提高准确性和特异性。

IF 1.8 4区化学

Analytical Letters Pub Date : 2025-04-29 DOI: 10.1080/00032719.2025.2496934

Chamindu Liyanapatirana, Frank X Weber, James M Harrington, Laura G Haines, Reshan A Fernando, Keith E Levine, Suramya Waidyanatha

{"title":"Quantitation of Arsenic in biological matrices: Use of Sector Field Inductively Coupled Plasma-Mass Spectrometry for Improved Accuracy and Specificity.","authors":"Chamindu Liyanapatirana, Frank X Weber, James M Harrington, Laura G Haines, Reshan A Fernando, Keith E Levine, Suramya Waidyanatha","doi":"10.1080/00032719.2025.2496934","DOIUrl":"10.1080/00032719.2025.2496934","url":null,"abstract":"Arsenic (As) and As-containing compounds have a wide array of applications in medicine, industry, and agriculture and has been associated with adverse health outcomes. In support of studies investigating the toxicity and toxicokinetic behavior of arsenic compounds, we developed and validated a high-resolution sector field inductively coupled plasma mass spectrometry (SF-ICP-MS) method to quantitate total arsenic in Sprague-Dawley (SD) rat plasma and heart. Primary matrix standard curves prepared in male SD rat plasma were linear (r ≥ 0.999) over the range of 5 to 1250 ng As/mL plasma with accuracy determined as relative error (RE) was ≤ ±20% at the lower limit of quantitation (LLOQ) of 5 ng/mL and ≤ ±15% for all other concentrations. The method limit of detection (LOD) was 0.728 ng/mL plasma. Mean extraction recovery was 96.7%, with a relative standard deviation (RSD) of 4.0%. The method demonstrated acceptable inter- (≤ ±7.3% RE and ≤ 8.0% RSD) and intra-day (≤ ±14.9% RE and ≤ 6.8% RSD) accuracy and precision. Method selectivity was ≤ 20% of the response for the LLOQ. Method performance was also evaluated in SD rat heart by preparing QC samples in heart homogenate and quantifying using plasma calibration curve. The mean RE value was -3.8% and the RSD value was 3.4% demonstrating that the method is suitable for quantitation of arsenic in rat heart.","PeriodicalId":7788,"journal":{"name":"Analytical Letters","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discrimination of Lutidine Isomers by Ion Mobility Spectrometry Using α-Cyclodextrin and Metal Ions α-环糊精和金属离子离子迁移谱法鉴别芦替丁异构体

4区化学

Analytical Letters Pub Date : 2025-04-23 DOI: 10.1080/00032719.2025.2494743

Long Chen, Jianglong Du, Xiaopeng Peng, Jiacheng Ye, Keqi Ye, Yinghua Yan, Chuan‐Fan Ding

{"title":"Discrimination of Lutidine Isomers by Ion Mobility Spectrometry Using α-Cyclodextrin and Metal Ions","authors":"Long Chen, Jianglong Du, Xiaopeng Peng, Jiacheng Ye, Keqi Ye, Yinghua Yan, Chuan‐Fan Ding","doi":"10.1080/00032719.2025.2494743","DOIUrl":"https://doi.org/10.1080/00032719.2025.2494743","url":null,"abstract":"The identification and separation of isomers are of great significance due to the distinct physicochemical properties and wide-ranging applications. In this study, a simple and rapid method based on ion mobility spectrometry (IMS) was developed to distinguish and relatively quantify the 2,5/3,5-lutidine (2,5/3,5-LUT) isomers. Initially, the two isomers were separated through complexation with α-, β-, and γ-cyclodextrins (CDs), with a slight inter-peak resolution observed in the formation of the [CD+LUT+H]+ complexes. To enhance the differentiation, metal ions (Mn2+, Fe2+, Co2+, Zn2+) were introduced to form ternary complexes, and α-CD in coordination with Zn2+ yielded the most effective separation of 2,5/3,5-LUT. Theoretical conformations of [α-CD + 2,5/3,5-LUT+H]+ and [α-CD + 2,5/3,5-LUT+Zn-H]+ were optimized. Furthermore, collision-induced dissociation (CID) analysis of the [α-CD + 2,5/3,5-LUT+Zn-H]+ complexes revealed that the dissociation energy varies due to different spatial conformations. Finally, the method demonstrated reliable relative quantification, achieving a satisfactory linear correlation (R2>0.99). The developed approach offers a simple, precise, and cost-effective strategy for isomer identification and conformational analysis, with potential applications in chemical and pharmacological fields.","PeriodicalId":7788,"journal":{"name":"Analytical Letters","volume":"59 4","pages":"583-593"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Green Deep Eutectic Solvent Assisted Solid-Phase Extraction (DESA-SPE) for the Simultaneous Preconcentration of 18 Elements with Determination by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) 绿色深共晶溶剂辅助固相萃取（DESA-SPE）同时富集18种元素并电感耦合等离子体质谱（ICP-MS）测定

4区化学

Analytical Letters Pub Date : 2025-04-17 DOI: 10.1080/00032719.2025.2492757

Zhisen Liang, Ling Xiao, Yuzhen Chen, Peilin Huo, Xurong Yao, Xiuying Li

引用次数: 2

L-Tryptophan/Levofloxacin-Based Ratiometric Fluorescence Biosensor for Escherichia coli by a Portable Device 基于l -色氨酸/左氧氟沙星的便携式大肠杆菌比例荧光生物传感器

4区化学

Analytical Letters Pub Date : 2025-03-30 DOI: 10.1080/00032719.2025.2483323

Tang Li, Ruobo Chen, Jun Liao, Yi Fan, Ruidong Meng, Fu Li, Jia Li

引用次数: 0

Synthesis of a Turn-On Isophorone-Based Near-Infrared Fluorescent Probe for Specific Recognition of Carboxylesterase 2 and Bioimaging 羧酸酯酶2特异性识别近红外荧光探针的合成及生物成像研究