{"title":"[Symposium: Usefulness and limitations of various methods in diagnosing myocardial ischemia].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"1-129"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14553021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Tsuiki, M Oguma, I Kubota, I Ohta, I Tono-Oka, S Yasui
{"title":"[Predictability of stress-induced myocardial ischemia from coronary arteriography in patients with organic coronary artery stenosis].","authors":"K Tsuiki, M Oguma, I Kubota, I Ohta, I Tono-Oka, S Yasui","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A quantitative index for describing the severity and extent of coronary artery disease has not been established yet, although it is certain that the stenosis causes myocardial ischemia induced by stress. To establish the most meaningful scoring system, we developed the grading of stenosis which is \"critical\" or significant in the single-, double-, and triple-vessel method (SDT), and the extent of improvement in the predictive value which may be induced by accounting for the predominance of the three major coronary arteries nourishing the left ventricle. Thirty-three patients (six were women), whose average age was 58.6 years, all having exertional angina pectoris and fixed organic coronary artery stenosis documented by coronary arteriography, but no old myocardial infarction, were the subjects of this study. For these patients the mean redistribution index (RDI) was determined by ergometer stress myocardial perfusion imaging using 201T1. The number (nST) of significant ST segment depressions by body surface ECG mapping after treadmill stress tests was compared with the sigma Pujadas grade, which is the sum of each grade assigned to each of the three major coronary arteries, and with the Pujadas score, which is the weighted sum of grades by dominance in the coronary artery distribution. The SDT method was a better predictor of ischemia if the criterion for critical stenosis is selected at a more severe stenosis (greater than 90% diameter stenosis). Among factors predicting ischemia, the length of the stenosis and the presence of collaterals did not seem to be definitive. However, the distribution of the arteries was an important factor.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14555423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B H Kim, M Inoue, Y Ishida, Y Tsuneoka, T Hiraoka, M Fukushima, M Matsumoto, H Abe, T Minamino
{"title":"[Radionuclide ventriculographic assessment of cardiac function based on the analysis of cardiac reserve during dynamic exercise].","authors":"B H Kim, M Inoue, Y Ishida, Y Tsuneoka, T Hiraoka, M Fukushima, M Matsumoto, H Abe, T Minamino","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To evaluate the contribution of myocardial contractility and preload to increase cardiac output during supine bicycle exercise, quantitative radionuclide ventriculography was performed at rest (R) and during peak exercise (Ex) in 43 patients with coronary artery disease (CAD) and 13 normal subjects. Myocardial contractility was estimated from the ratio of peak systolic pressure to end-systolic volume index (P/V index). During Ex in normal subjects, P/V index invariably increased and its percent change from R to Ex averaged 98 +/- 46 percent. Stroke index (SI) in normal subjects increased from 48 +/- 9 to 57 +/- 7 ml/m2 during Ex (p less than 0.001) without an increase in end-diastolic volume index (EDVI) (76 +/- 11 vs 78 +/- 11 ml/m2, NS). Ten of 43 patients with CAD, whose percent increase in P/V index was more than 40 percent, showed a significant increase in SI during Ex (44 +/- 5 vs 51 +/- 12 ml/m2, p +/- 0.05) without an increase in EDVI (86 +/- 14 vs 87 +/- 15 ml/m2, NS). In 16 of 43 patients with CAD whose percent increase in P/V index was less than 40 percent, SI increased from 44 +/- 10 to 51 +/- 15 ml/m2 (p less than 0.01) during Ex with an increase in EDVI (102 +/- 24 vs 117 +/- 29 ml/m2, p less than 0.001). In the remaining 17 patients with CAD whose P/V index decreased during Ex, SI did not increase during Ex (48 +/- 14 vs 44 +/- 12 ml/m2, NS) despite an increase in EDVI (80 +/- 19 vs 94 +/- 18 ml/m2, p less than 0.01). These results indicate that the Frank-Starling mechanism operates under limited augmentation in myocardial contractility, and that its compensatory function may have limitations under the severely depressed reserve of myocardial contractility.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 8","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14146851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The First Conference on Mitral Valve Prolapse. Tokyo, August 3, 1984].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 11","pages":"1-152"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14801386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnosis of mitral valve prolapse by X-ray CT and MRI].","authors":"Y Masuda, Y Inagaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To evaluate the usefulness of enhanced X-ray CT and gating magnetic resonance imaging (MRI) for diagnosing mitral valve prolapse, three patients with this abnormality and several controls were examined by these two methods. The mitral valve was not recognized by X-ray CT except a few cases with thickened mitral valve. However, MRI could demonstrate clearly the mitral leaflets and annulus in many subjects. In transverse MR imaging of the subjects without valvular disease, the closed mitral valve showed V-shaped appearance in the left ventricle during systole. In a patient with marked mitral valve prolapse, MRI revealed buckling of the posterior mitral leaflet into the left atrium, and in two other patients with mild mitral valve prolapse, MRI demonstrated displacement of coaptation of the anterior leaflet toward the left atrium. These results suggest MRI is a useful method for diagnosing mitral valve prolapse.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 11","pages":"131-9"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14801390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pathologic aspects of mitral valve prolapse syndrome].","authors":"S Kawai, R Okada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To comprehend clinical pictures of mitral valve prolapse syndrome (MVP), specific pathoanatomical knowledge is required. There is no definite structure of the anterior mitral valve ring. The mitral valve ring is not flat; the anterior segment of the ring tilts up superiorly. The number of scallops of the posterior leaflet depends on the definition of the incisura. The term \"rough zone chorda\" (Lam et al., 1970) is a misnomer. From the pathological point of view, more than two subgroups of MVP are present. In isolated MVP, pathological lesions are restricted to the local ballooned segment. However, in MVP with connective tissue disorders (for example, Marfan syndrome, etc.), the lesions are principally diffuse. Mitral valve changes in hypertrophic cardiomyopathy with obstruction are caused by torsion and the relatively elongated anterior leaflet due to narrowing of the mitral orifice, septal hypertrophy and displacement of the papillary muscles. MVP in atrial septal defect is caused by the turbulence of a large shunt flow or by the torsion of the mitral ring due to right ventricular volume overload. Further investigation of surgical and necropsied cases will be required to clearly the subgroups of MVP.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 11","pages":"19-34"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14801392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Mitsudo, T Fujino, K Matsunaga, O Doi, Y Nishihara, J Awa, T Goto, T Hase, K Kadota, M Kin
{"title":"[Intracoronary thrombolysis for high risk patients with acute myocardial infarction].","authors":"K Mitsudo, T Fujino, K Matsunaga, O Doi, Y Nishihara, J Awa, T Goto, T Hase, K Kadota, M Kin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifty-four patients with acute myocardial infarction (AMI) were treated by percutaneous transluminal coronary recanalization (PTCR) within six hours after onset of symptoms or at the time of emergency coronary angiography. Of these, six patients had neither good collaterals nor recanalization, and followed by mechanical failure due to rupture of the left ventricular free wall or interventricular septum in five patients despite antihypertensive therapy. In the remaining 48 patients with good collaterals or recanalization, mechanical failure was statistically infrequent and occurred in only two patients (p less than 0.001). Ninety-four patients treated by PTCR were assessed in terms of mortality, cause of death and their hemodynamic findings. Cardiac deaths occurred in nine patients (9.6%); mechanical failure, in four; and cardiogenic shock due to the occlusion of the left main trunk, in five. Cardiac death was more frequently encountered in the era of the initial stage of PTCR (six of 53 cases: 11.3%) and the main cause was mechanical failure (four of six cases). On the other hand, cardiac death in recent years of PTCR was less (three of 41 cases: 7.3%), and all three had pump failure due to the occlusion of the left main trunk. Risk of mechanical failure was successfully resolved using intra-aortic balloon pumping and beta-blocker in addition to antihypertensive therapy. At the present time, PTCR and other supplementary therapy mentioned above reduced the mortality from mechanical failure and cardiogenic shock, but occlusion of the left main trunk remains an important cause of death in patients with AMI.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 10","pages":"47-53"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14089222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Nomura, R Fukui, Y Miyagi, Y Shiga, M Uwatoko, H Nakano, Y Abo, H Chikamatsu, H Hishida, Y Mizuno
{"title":"[The effects of intravenous urokinase administration in patients with acute myocardial infarction].","authors":"M Nomura, R Fukui, Y Miyagi, Y Shiga, M Uwatoko, H Nakano, Y Abo, H Chikamatsu, H Hishida, Y Mizuno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of intravenous urokinase administration were assessed in patients with acute myocardial infarction (AMI). Of 146 patients with AMI, 101 were admitted within 12 hours of onset of chest pain, and classified in four groups according to the method of administering urokinase. PTCR group (15 cases); PTCR was performed within six hours of onset, using less than 960,000 I.U.; Group A (20 cases); 1.5 million I.U. administered in one hour or 960,000 I.U. in 30 min; Group B (48 cases); 240,000 I.U. in two hours; and 4) Group C (18 cases); 240,000 I.U. in 12 hours. In groups A, B and C, urokinase was administered intravenously. The remaining 45 patients did not receive urokinase, and served as a control group. In the chronic stage, infarction-related coronary arteries were patent at rates of 93% in the PTCR group, 82% in group A, 76% in group B, 62% in group C, and 46% in the control group. In the PTCR group and in group A, alpha 2-plasmin inhibitor showed a steep decline to the lowest level on the day after urokinase administration, as did the summation of elevation of ST segments in conventional twelve-lead electrocardiograms. Peak CK times, which represent the duration (hours) from onset to the peak serum CK value increased in the following order: 13.3 +/- 4.8 in the PTCR group, 17.3 +/- 4.9 in group A, 17.3 +/- 6.9 in group B, 20.7 +/- 6.7 in group C and 22.5 +/- 6.4 in the control group. These data suggest early recanalization of occluded coronary arteries in the group A, and intravenous administration of high doses of urokinase in the early phase of AMI seemed to contribute to salvage the ischemic myocardium. However, assessment of ventricular wall motion by two-dimensional echocardiography failed to confirm appreciable improvement in the PTCR group and group A in comparison with the other groups.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 10","pages":"23-33"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14089220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comments on the diagnostic criteria of mitral valve prolapse].","authors":"J Yoshikawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two-dimensional echocardiography has been the reference standard for establishing the clinical diagnosis of mitral valve prolapse. Superior systolic displacement of the mitral leaflets, however, is not necessary abnormal. Whether and at what point leaflet displacement uniquely describes a pathologic process should not be accepted without defining the pattern of normal mitral leaflet motion. One should combine informations from phonocardiograms, Doppler color flow mapping and two-dimensional echocardiograms in an effort to avoid the artifice of using two-dimensional echocardiography as a categoric reference standard and to establish new clinical guidline or criteria that distinguish pathologic mitral valve prolapse from normal superior systolic displacement of the mitral leaflets. Mitral valve prolapse is a dynamic disease that results in varying clinical and morphologic presentations depending upon the degree of structural abnormality. Therefore, clinical and morphologic studies are required in not only severely symptomatic patients but also perfectly asymptomatic patients.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 11","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14800543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Percutaneous transluminal coronary angioplasty: technical and anatomical considerations].","authors":"M Nobuyoshi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Four hundred and sixty-four coronary obstructive lesions of 321 patients were dilated by elective percutaneous transluminal coronary angioplasty (PTCA) from October 1981 to September 1984. The overall success rate was 72% (334 of 464 vessels). With respect to the sites of procedure, the success rate was 74% (192 of 260 lesions) in the left anterior descending artery (LAD), 74% (71 of 96 lesions) in the left circumflex artery (LCx), 66% (67 of 102 lesions) in the right coronary artery (RCA), 75% (three of four grafts) in bypass graft, and 50% (one of two lesions) in the left main trunk. The success rate related to the total number of diseased vessels was 79% (157 of 200 lesions) in one-vessel disease, 62% (110 of 177 lesions) in two-vessel disease, and 77% (63 of 82 lesions) in three-vessel disease. Considering the learning curve, the success rate was 52% to 56% for the initial 150 lesions, and 80% thereafter. Complications of elective PTCA were three deaths (0.9%), nine emergency A-C bypasses (2.8%), seven myocardial infarctions (2.2%), and three hemopericardia (0.9%). The success rate of PTCA was evaluated in regards to the morphology of the target lesion. There was no difference between narrowing more than 99% and narrowing less than 99%, though the success rate of diffuse stenosis was lower than that of the tubular or short lesion. The existence of previous myocardial infarction and ulcerating plaques did not relate to the success rate. Calcification or tortuosity significantly decreased the success rate. Length of anginal history did not relate to the success rate.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":" 10","pages":"55-61"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14089223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}