Journal of cardiography. Supplement最新文献

{"title":"[Comparative sensitivities of exercise, isoproterenol infusion and cold pressor tests for detecting myocardial ischemia].","authors":"R Ajisaka,&nbsp;T Takeda,&nbsp;T Fujita,&nbsp;K Iida,&nbsp;K Yukisada,&nbsp;K Iida,&nbsp;M Matsuda,&nbsp;Y Sugishita,&nbsp;I Ito,&nbsp;M Akisada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The comparative sensitivities of exercise (supine ergometer), isoproterenol (ISP) infusion and cold pressor test (CPT) for detecting myocardial ischemia in patients with effort angina (45 cases) and vasospastic angina (16 cases) were investigated. Twenty-three patients with atypical chest pain served as normal controls. Left ventricular function was evaluated by computerized quantitative analysis using the following three graphic methods: 1) radionuclide angiography during exercise (EX-RI) and ISP infusion (ISP-RI), 2) two-dimensional echocardiography during ISP infusion (ISP-2DE) and CPT (CP-2DE) and 3) digital subtraction angiography during CPT (CP-DSA). The incidence of regional wall motion abnormalities (WMA) induced by these three stress tests in patients with effort angina were as follows: 83% in EX-RI, 80% in ISP-2DE, 80% in ISP-RI, 75% in CP-2DE and 86% in CP-DSA. In patients with vasospatic angina, the WMA were as follows: 40% in EX-RI, 0% in ISP-RI and 71% in CP-DSA. In patients with atypical chest pain, the WMA were 0% in EX-RI, 0% in ISP-RI, 8% in ISP-2DE, 13% in CP-2DE and 13% in CP-DSA. The left ventricular ejection fraction (EF) was unchanged during ISP (from 65 +/- 11% to 68 +/- 12%) and it decreased both during exercise (from 64 +/- 10% to 58 +/- 9%, p less than 0.05) and during CPT (from 69 +/- 10% to 65 +/- 9%, p less than 0.05) in patients with effort angina. In patients with vasospastic angina, the EF was unchanged both during exercise (from 70 +/- 7% to 68 +/- 13%) and during the CPT (from 76 +/- 5% to 75 +/- 4%), while it increased during ISP infusion (from 63 +/- 8% to 79 +/- 7%, p less than 0.01). In patients with atypical chest pain, the EF was increased both during exercise (from 72 +/- 7% to 79 +/- 5%, p less than 0.01) and during ISP infusion (from 67 +/- 5% to 78 +/- 7%, p less than 0.01), while it was unchanged during CPT (from 77 +/- 7% to 76 +/- 8%). In exercise and in ISP infusion tests, WMA were provoked concomitantly with ST segment deviations in nearly all patients. However, during CPT, WMA were produced without the occurrence of ST segment deviations. Myocardial ischemia due to organic coronary artery stenosis was difficult to distinguish from coronary artery spasm by exercise test. However, the susceptibility to ISP infusion and CPT differed in producing WMA in patients with vasospastic angina.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"3-18"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14451411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Myocardial perfusion detected using digital subtraction angiography as compared with X-ray CT and Tl-201 myocardial imaging].","authors":"M Ohta,&nbsp;H Fukuoka,&nbsp;H Naito,&nbsp;T Nishimura,&nbsp;K Kimura,&nbsp;M Takamiya,&nbsp;K Ohara,&nbsp;T Kozuka,&nbsp;M Ohe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty-two patients who underwent aorto-coronary bypass surgery were examined with intra-aortic digital subtraction angiography (IADSA) to detect abnormalities of myocardial blood perfusion. Tl-201 myocardial imaging and cardiac X-ray CT were performed nearly simultaneously about one month postoperatively. Cardiac imaging using IADSA was performed at a rate of 30 frames/sec with matrix size of 512 x 256. Time density curves of each pixel in the region of the myocardium of the left ventricle were post-processed to obtain functional images. The maximal concentration (Cmax), integration of the time-density curve (Cinteg), mean transit time (MTT), Cmax/MTT and Cinteg/MTT were computed for each pixel. Cmax and Cinteg are parameters related to the volume of the coronary vascular bed. Cmax/MTT and Cinteg/MTT are parameters related to the regional myocardial blood flow. These functional images showed hypoperfusion areas in 35 of 37 ischemic segments confirmed by wall motion in digital subtraction left ventriculography, Tl-201 myocardial imaging and ECG. Normal perfusion areas of the functional images were observed in 18 of 54 infarcted segments. These results show the complexities of myocardial perfusion in old myocardial infarction.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"69-79"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14451412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Left anterior descending artery lesions estimated by the rest T map in patients with angina pectoris].","authors":"T Ishikawa,&nbsp;H Hayashi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>T potential distributions (T map) based on 87-lead unipolar electrocardiograms over the body surface were analyzed in 25 cases of angina pectoris without a history of acute myocardial infarction. Ten cases (40%) were selected according to the characteristic T map finding, in which there is an island or bay formation of negative potential downward from the left shoulder into the positive area located on the chest anteriorly. Their coronary angiography (CAG) and left ventriculography (LVG) were reviewed. In three cases which received percutaneous transluminar coronary angioplasty (PTCA), paired T maps were obtained before and after this procedure. All 10 cases had significant stenosis (more than 90%) at proximal or mid-portion in the left anterior descending artery, and six cases had single vessel disease. Asynergy at anterolateral, apical or septal segment was shown in LVG in six cases (60%). Improvement of the lesion by a successful PTCA restored the normal T potential distribution. We conclude that the rest T map abnormality described above is closely related to ischemia at the anterior wall of the left ventricle and interventricular septum secondary to the lesions in the proximal or mid-portion of the left anterior descending artery. Therefore, the rest T map can be applied to estimate the extent of the coronary lesions and to further evaluate electrocardiographically the effect of PTCA on ischemia in the left ventricle.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14555424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Quantitative evaluation of regional myocardial blood flow by digital subtraction angiography: correlations with exercise electrocardiography and Tl-201 myocardial scintigraphy].","authors":"H Ikeda,&nbsp;K Shibao,&nbsp;R Yamaguchi,&nbsp;M Yoh,&nbsp;M Shimamatsu,&nbsp;K Hiyamuta,&nbsp;K Itaya,&nbsp;Y Ohkita,&nbsp;K Sugi,&nbsp;Y Koga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We previously reported that the contrast disappearance half-life (T1/2) derived by the computerized washout analysis of digital subtraction coronary arteriograms provides a useful index for quantitatively evaluating regional myocardial blood flow. In the present study, we further evaluated the clinical usefulness of T1/2, comparing it with exercise electrocardiography and exercise thallium-201 myocardial scintigraphy. The study subjects consisted of 25 patients with angina pectoris and 14 patients with normal coronary arteries. Following the manual injection of contrast media into the left anterior descending coronary artery (LAD), a time-density curve was generated in the sectors of the myocardium which were perfused by the LAD and the T1/2 was calculated. T1/2 values correlated closely with double product (r = -0.73). They were significantly greater in patients with exercise-induced ST depression (8.3 +/- 1.0 vs 5.8 +/- 0.7, p less than 0.005). In addition, there was a good correlation between T1/2 values and washout ratio as determined by exercise thallium-201 myocardial scintigraphy, with r = -0.83. Although T1/2 values were within the normal range (mean +/- 2SD of control subjects) in all patients with LAD stenosis of 50 percent or less, these values were abnormally increased, exceeding the normal range, in 11 of the 12 patients with stenosis of 90 percent or more. Compared with exercise electrocardiography, T1/2 values were abnormally prolonged in 11 of the 13 patients with exercise-induced ST depression. Compared with exercise thallium-201 myocardial scintigraphy, T1/2 values were abnormally prolonged in seven of the nine patients with transient perfusion defects.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"81-9"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14449622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Stress Tl-201 myocardial single photon emission computed tomography in diagnosing ischemic heart disease: its value and limitations].","authors":"Y Futagami,&nbsp;T Yada,&nbsp;M Yamamuro,&nbsp;T Konishi,&nbsp;T Nakano,&nbsp;H Takezawa,&nbsp;H Maeda,&nbsp;T Nakagawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The value and limitations of stress 201T1 myocardial single photon emission computed tomography (SPECT) for diagnosing ischemic heart disease (IHD) was studied. Using a dual-head rotating gamma camera system, stress SPECT and conventional planar imaging were performed for 138 patients while they were examined by symptom-limited graded bicycle ergometer exercise. All patients underwent selective coronary arteriography and left ventriculography, and 93 had myocardial infarction (MI), 30 had effort angina (EA) and 15 were normal (control). Sensitivities for detecting IHD (SPECT: planar = 96%: 89%, p less than 0.01), individual coronary arterial lesions (left anterior descending artery = LAD, 84%: 68%, p less than 0.005; left circumflex artery = LCX, 60%: 47%, NS; right coronary artery = RCA, 88%: 69%, p less than 0.01), multivessel disease (= LAD + LCX and/or RCA, 53%: 31%, p less than 0.025), and three vessel disease (60%: 13%, p less than 0.005) were significantly higher by SPECT than by planar imaging. In addition, detection of ventricular aneurysms by SPECT was possible with a reasonably high sensitivity (94%) and specificity (84%). Signs of aneurysm included 1) an extensive anterior permanent defect, 2) a large left ventricular cavity, and 3) widening of the angle composed by the septal and lateral walls toward the apex in transaxial images. Sensitivity for detecting IHD was significantly lower in patients without MI (i.e., EA) than in patients with MI (MI: EA = 100%: 83%, p less than 0.005). Sensitivity for detecting individual coronary arterial lesions was lower in the absence than in the presence of MI (LAD; 77%: 87%, LCX; 38%: 68%, RCA; 71%: 90%, respectively), with multivessel disease than with single vessel disease, and with mild than with severe grade of stenosis. Sensitivity for detecting multivessel disease was lower in patients without MI than in those with MI (31%: 61%, respectively), and in anterior MI than in posteroinferior MI, or both MIs (36%: 69%: 100%, respectively). Stress-induced ischemia of infarcted area (anterior MI, 36%; posteroinferior MI, 24%) and ventricular aneurysm (anterior MI, 21%; posteroinferior MI, 0) masked other coronary arterial stenoses in patients with previous MI. We concluded that stress 201T1 myocardial SPECT was a useful non-invasive technique for detecting IHD and individual coronary arterial lesions, multivessel disease (especially posteroinferior MI and anterior + posteroinferior MI), three vessel disease and ventricular aneurysms. However, there were limitations in detecting multivessel disease in patients with anterior MI and EA.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"91-106"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14625088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Coronary arterial spasm and symptomatology in ischemic and non-ischemic heart diseases: study of the ergonovine maleate provocative test in 3,000 consecutive patients].","authors":"H Nosaka,&nbsp;M Nobuyoshi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We performed coronary angiography and ergonovine maleate provocative tests (EM test) for 3,000 consecutive patients to clarify 1) the incidence of coronary arterial spasm and significant fixed organic stenosis in ischemic and non-ischemic heart diseases, and 2) the relation of these angina-inducing mechanism(s) to rest (R), effort and rest (E & R), and effort (E) angina. Coronary arterial spasm was defined as total or subtotal occlusion induced by ergonovine test, and fixed stenosis was defined as stenosis with more than 70% narrowing of luminal diameter measured after administration of isosorbide dinitrate. Subjects consisted of 3,000 consecutive patients and were categorized in four groups including 1,145 patients who had typical angina pectoris (Group I: rest angina 653, effort angina 230, and combined rest and effort angina 262), 398 patients with myocardial infarction (Group II), 648 patients with atypical chest pain (Group III), and 809 patients who eventually had diagnostic catheterization for heart diseases other than of ischemic nature (Group IV). Results were as follows: 1. The incidence of coronary artery spasm was 22.2% in Group I, 22.9% in Group II, 1.2% in Group III, and 3.7% in Group IV. 2. In Group I, there was a close relationship between the mechanism of angina and the type of occurrence of typical chest pain; coronary artery spasm was more likely observed in rest angina, organic stenosis was observed in effort angina, and the combined type was observed in cases with both spasm and organic stenosis. Furthermore, the occurrence of coronary artery spasm was significantly more frequent in cases with single vessel disease compared with those with multivessel disease (50.7% vs. 26.7%, p less than 0.005). 3. In Group II, the most frequent angiographic evidence was fixed organic stenosis, and there was no relationship between spasm and the numbers of diseased vessels. 4. In Groups III and IV, the most common entity causing coronary artery spasm was hypertrophic cardiomyopathy. In conclusion, two major mechanisms of angina pectoris, i.e., coronary artery spasm and organic stenosis, are closely related to the symptomatology of this disease, such as rest, effort and combined rest and effort types.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"35-47"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14555425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Assessment of perfusion defects by intracoronary myocardial contrast echocardiography].","authors":"C Tei,&nbsp;H Tanaka,&nbsp;T Sakamaki,&nbsp;P M Shah","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Myocardial contrast echocardiography has developed rapidly in the last few years. This paper is a review of this method based on our previous studies performed in 43 closed chest dogs. An injection of 2 ml of an agitated saline-Renografin mixture into the left main coronary artery provided contrast opacification of the entire circumference of the left ventricular myocardium. Contrast injection into the left anterior descending or the circumflex artery resulted in contrast opacification of localized regions of the left ventricle. Contrast injection into the left main coronary artery after a selective coronary artery occlusion resulted in a \"negative\" contrast outline of the corresponding area indicating the underperfused myocardium. The physiological and hemodynamic effects of the intracoronary injection of the contrast material appeared minor and brief. Perfusion defects after coronary artery occlusion assessed by myocardial contrast echo correlated well with those in equivalent sections by monastral blue dye injected into the left ventricle. Furthermore, the extent of myocardial necrosis after five hours of coronary occlusion assessed by myocardial contrast echo correlated well with the area of necrotic myocardium in equivocal slabs. Myocardial contrast washout index (T1/2) measured by digital intensity analysis of successive end-diastolic images was found to be significantly changed in dogs with varying degrees of coronary stenosis. Thus, the measurement of T1/2 appears to be feasible for evaluating degree of coronary stenosis, however, numerous technical problems remain to be clarified.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"59-67"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14555427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ultrasonic tissue characterization in diagnosing myocardial infarction].","authors":"Y Sakabe,&nbsp;H Hishida,&nbsp;K Kawamura,&nbsp;Y Murashima,&nbsp;K Kodama,&nbsp;Y Sugiura,&nbsp;K Hagiwara,&nbsp;Y Mizuno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To evaluate myocardial tissue changes using two-dimensional (2D) echocardiography, several approaches were attempted. 1. Quantitative evaluation of the myocardial echo intensity by computerized image processing in patients with old anteroseptal myocardial infarction: 2D echocardiograms of the parasternal long-axis view were converted to digital images to measure the echo intensity of the regions of interest (ROI) placed in the interventricular septum (IVS), the left ventricular posterior wall (LVPW), the left ventricular cavity, and the pericardium. The mean value of the echo intensity was compared with that of the pericardium (maximum echo intensity) and of the left ventricular cavity as the minimum. In 12 normal subjects, the relative echo intensity of the IVS was 0.40 +/- 0.05 (mean +/- SE), whereas it was 0.71 +/- 0.06 in 11 patients with old MI (p less than 0.001). Color display facilitated the visual recognition of the numerical differences in echo intensities. 2. Evaluation of the myocardial echo intensity in acute phase of myocardial infarction: In nine normal elderly persons, the relative echo intensity of IVS was 0.29 +/- 0.14, and there was no significant change in the early stage (three to seven days) of acute infarction (0.31 +/- 0.14). Two weeks later, however, a significant increase was noted (0.61 +/- 0.10) (p less than 0.01), probably due to an increase in collagen fibers. 3. Changes of the myocardial echo intensity in acute myocardial ischemia: Two-dimensional echocardiograms were recorded in nine open-chest dogs using 3 and 5 MHz transducers before and 10 min, 1 hr, 3 hrs, and 6 hrs after coronary artery ligation. With the 5 MHz transducer, the echo intensity of the ischemic myocardium was decreased after 10 min and was remarkable after 1 hr (0.24 +/- 0.08), and restored in six hrs. These changes could not be detected using the 3 MHz transducer. 4. An in vitro study for assessment of ultrasonic attenuation in the canine infarcted myocardium: The frequency dependency of ultrasonic attenuation of the resected canine myocardium in the frequency region of 2 MHz to 7 MHz was estimated one and two weeks after coronary artery ligation. The distributions of attenuation characteristics were nearly consistent with those of collagen contents determined histologically. In conclusion, we demonstrated that acute and chronic ischemia of the myocardium influences the transmission and reflection of ultrasound. By applying this property, ultrasonic tissue characterization may become a useful tool for detecting myocardial ischemia in the near future.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"49-58"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14555426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnostic evaluation of ischemic heart disease by X-ray computed tomography and magnetic resonance imaging].","authors":"Y Masuda,&nbsp;S Kobayashi,&nbsp;J Takasu,&nbsp;M Sakakibara,&nbsp;H Imai,&nbsp;Y Aoyagi,&nbsp;N Morooka,&nbsp;S Watanabe,&nbsp;Y Inagaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To assess the usefulness of X-ray computed tomography (CT) and magnetic resonance imaging (MRI) in detecting and evaluating ischemic heart disease, conventional and enhanced CT were performed for 180 patients (150 with transmural infarction, 12 with subendocardial infarction, and 18 with angina pectoris). MRI examinations were performed for 38 patients (31 with transmural infarction, three with subendocardial infarction, and four with angina pectoris). With enhanced CT, two findings in the myocardium were direct evidence of myocardial infarction: 1. filling defects on the early scans, and 2. late enhancement of the myocardium on the delayed scans. The former were observed mainly at the sites of recent anterior myocardial infarction and the latter were seen in about half of the patients with recent and remote anterior myocardial infarctions. However, these findings were inadequately imaged in patients with inferoposterior infarction and subendocardial infarction. Among 137 patients with transmural infarction, enhanced CT revealed left ventricular aneurysms in 51 (37%) and ventricular thrombi in 26 (19%). ECG-gated MRI apparatus having a superconducting magnetic operating at 0.25 Tesla was used, and data for this study were collected using the single-slice spin echo technique. In eight of nine patients with acute myocardial infarction, gated MRI demonstrated the infarcted myocardium as regions of high signal intensity relative to that of the adjacent normal myocardium. Such a difference in MRI signal intensity was scarcely recognized in the chronic stage of myocardial infarction, but the indirect findings of infarction, such as regional wall thinning, wall motion disturbances, left ventricular aneurysms, and ventricular thrombi were easily detected using MRI. No characteristic finding was obtained by CT or MRI in patients with angina pectoris.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"117-28"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14553022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exercise 13NH3-positron emission computed tomography (PET) versus exercise single photon emission computed tomography (SPECT)].","authors":"R Nohara,&nbsp;H Kambara,&nbsp;C Kawai,&nbsp;Y Yonekura,&nbsp;M Senda,&nbsp;H Saji,&nbsp;K Torizuka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The value of exercise positron emission computed tomography (PET) was determined by comparing it with exercise T1-201 single photon emission computed tomography (SPECT) using graded ergometer exercise in 10 anginal patients with left anterior descending coronary (LAD) involvement (stenosis greater than or equal to 75%) with or without other coronary stenosis. The distribution of N-13 ammonia or T1-201 was determined and expressed as percent count ot the highest count on the circumferential profile curve (CPC) in the transaxial image. Two standard deviations below the mean counts of six normal hearts for PET and ten for SPECT were considered as the lower limit of normal, and these were determined separately during exercise and at rest. The ischemic areas per total myocardial areas (%C), the accuracy in diagnosing coronary involvement and the identification of coronary branch involvement were determined by CPC analysis in three corresponding slices. Regional analyses revealed that accuracy in diagnosing proximal left anterior descending artery (LAD) involvement was higher with PET (9/10) than with SPECT (7/10), but the difference was not statistically significant. The accuracy in diagnosing right coronary or circumflex artery stenosis was 9/10 with PET and 8/10 with SPECT (NS); the %C was significantly higher with PET than with SPECT during exercise (PET: mean +/- SD = 56 +/- 21%, SPECT: 35 +/- 21%, p less than .01) in spite of smaller double products (x10(3] (PET: 18.9 +/- 4.7, SPECT: 23.5 +/- 5.7, p less than .02). Thus, exercise PET was more reliable in evaluating regional ischemia and in semiquantifying the ischemic area in the myocardium.</p>","PeriodicalId":77861,"journal":{"name":"Journal of cardiography. Supplement","volume":"12 ","pages":"107-16"},"PeriodicalIF":0.0,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14625087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}