Anales Del Sistema Sanitario De Navarra最新文献

{"title":"Bilateral subgaleal hematoma after a robot-assisted radical prostatectomy: an uncommon complication.","authors":"Iñigo Rubio Baines,&nbsp;Antonio Martínez Simón,&nbsp;Francisco Javier Ancizu,&nbsp;Isidro Olavide,&nbsp;Cristina Honorato-Cía","doi":"10.23938/ASSN.1047","DOIUrl":"10.23938/ASSN.1047","url":null,"abstract":"<p><p>Robot-assisted radical prostatectomy is a relatively recent technique. Its advantages include less invasiveness and better pain management, but has specific anesthesia requirements, such as steep Trendelenburg position and pneumoperitoneum. Mild complications are common, e.g., transient hypotension or soft tissue edema. We present a case of a 62-year old male who developed subgaleal hematoma associated with transient neurologic impairment after surgery. Jugular vein insufficiency was suspected as the most likely cause. The patient recovered fully. Robot-assisted radical prostatectomy can be a challenging procedure due to the anesthesia requirements, but most complications are mild and transient. However, patients should be carefully assessed before surgery. We identified potential factors that may have led to this complication: the abnormal prolonged surgical time, the steep Trendelenburg, a non-assessed jugular vein insufficiency, and/or patient`s obesity.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/3c/assn-46-02-e1047.PMC10520747.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10146275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of mouthwashes on the microhardness of aesthetic composite restorative materials.","authors":"Noura Abdulaziz Alessa","doi":"10.23938/ASSN.1049","DOIUrl":"10.23938/ASSN.1049","url":null,"abstract":"<p><strong>Background: </strong>Mouthwashes are increasingly being used worldwide. However, these preparations are known to have a negative impact on composite resin dental restorations. In this study, we aim to evaluate the effect of mouthwashes on the microhardness of such restorations.</p><p><strong>Methods: </strong>Thirty specimens of Tetric N-Ceram composite were prepared. Each composite specimen was cured for 40 seconds and kept in saline solution for 24 hours at 37 °C. Baseline microhardness of each specimen was recorded using an Innovatest Vickers Micro Hardness Tester. Composite specimens were randomly placed in 20 mL of the selected mouthwashes (Colgate® Plax, Listerine® Teeth & Gum Defence, and Closeup® Antibacterial Mouthwash Cool Breeze) and stored in an incubator for 24 hours at 37 °C. Next, microhardness values were rechecked. pH measurements were recorded for each type of mouthwash using a digital pH meter.</p><p><strong>Results: </strong>Due to the acidic nature of Colgate® and Listerine®, the microhardness of the restorations decreased with these mouthwashes; Listerine® caused the greatest decrease in microhardness and had the lowest pH reading (4.34). For Closeup®, with a neutral pH (7.02), no negative effect on microhardness was found; on the contrary, due to the presence of zinc in this latter mouthwash, an increase of the microhardness was found.</p><p><strong>Conclusions: </strong>We confirm the negative effect of acidic mouthwashes on the microhardness of composite dental restorations.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/75/7a/assn-46-02-e1049.PMC10520749.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10128266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric analysis of the Psychiatric Diagnostic Screening Questionnaire (PDSQ) and determinants of psychopathology in two outpatient clinics in Navarre (Spain).","authors":"Juan I Arrarás,&nbsp;Manuel J Cuesta,&nbsp;Victor Peralta,&nbsp;Gustavo J Gil-Berrozpe,&nbsp;Laura Barrado,&nbsp;Olga Correa,&nbsp;Rebeca Elorza,&nbsp;Lorea González,&nbsp;Irma Garmendia,&nbsp;Lucía Janda,&nbsp;Patricia Macaya,&nbsp;Camino Núñez,&nbsp;Pablo Sabater,&nbsp;Aileen Torrejon","doi":"10.23938/ASSN.1043","DOIUrl":"10.23938/ASSN.1043","url":null,"abstract":"<p><strong>Background: </strong>The self-report Psychiatric Diagnostic Screening Questionnaire PDSQ is designed to screen Axis I psychiatric disorders. We aim to determine its psychometric properties in Spanish outpatients and assess its relationship with two interviews (for psychopathology and for personality disorders) and clinical/demographic variables.</p><p><strong>Methodology: </strong>We administered the study questionnaire, the Mini International Neuropsychiatric Interview Plus (MINI-Plus), the Standardised Assessment of Personality Abbreviated Scale (SAPAS), and the List of Threatening Experiences Questionnaire (LTE-Q) to 375 patients at two public outpatient centres. Reliability of the study questionnaire was evaluated (Cronbach's alpha, ?) and known-group validity measured by comparing groups based on demographic and clinical variables (binary logistic regression analysis) and MINI-Plus diagnoses (Mann-Whitney U). The diagnostic accuracy of the study questionnaire score was analysed taking the MINI-Plus diagnoses as the gold standard (ROC analysis).</p><p><strong>Results: </strong>Internal consistency was adequate across all PDSQ scales (? >0.7; mean ?=0.85). Known-group comparisons were satisfactory. Female and male patients showed higher prevalence of internalizing and externalizing diagnoses, respectively. Younger age, more life events and limitations, higher SAPAS scores, and lower economic levels were linked to a greater number of PDSQ diagnoses. Inter-group differences were found for all PDSQ scales based on the corresponding MINI-Plus diagnoses. Mean values of sensitivity, AUC, and negative predictive value were 88.7, 0.82, and 96.7, respectively.</p><p><strong>Conclusions: </strong>When applied to a sample of Spanish outpatients, the PDSQ exhibits satisfactory psychometric properties and adequate relationships with the psychopathology and personality interviews, and clinical and demographic variables. The study questionnaire is suitable for assessing comorbidity and psychopathology dimensions.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/8a/assn-46-02-e1043.PMC10520750.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10128261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence of dental and mucosal lesions among the pediatric population who attended the emergency department of a general hospital].","authors":"Montserrat Suárez Ardura,&nbsp;María García-Pola,&nbsp;José Manuel Cuervo Menéndez","doi":"10.23938/ASSN.1041","DOIUrl":"10.23938/ASSN.1041","url":null,"abstract":"<p><strong>Background: </strong>The high prevalence of oral pathology in children encourages to gain further understanding on their manifestations and urgent nature, objective of the present study Methodology. Cross-sectional study that included patients aged <14 years of age who attended an emergency department over a one-year period. The relationship between the variables collected and oral pathology was analyzed.</p><p><strong>Results: </strong>Fifty-five patients were included, 45.5% girls, mean age 4.11 years (10 days to 13 years). Overall, mucosal pathology (74.5%) prevailed over dental ones, and lesions of infectious origin (54.6%) over the traumatic ones (14.5%). Dental pathology (50% toothache and 35.7% infections) was significantly associated with being >6 years (66.7 vs 10%), pain (40.7 vs 10.7%) and absence of fever (37.9 vs 11.5%). Mucosal pathology (61% infections: 53.7% viral and 31.7% due to herpangina) was significantly associated with being =6 years (60 vs 6.7%) and having fever (76.9 vs 17.2%). Six traumatic lesions on the mucosa and two on the teeth were observed; significantly more patients attended the emergency room within 24 hours (median =1 hour) than in the case of infection (100 vs 51.7%). Being =6 years was significantly associated with fever, mucosal pathology, mucosal infection, and herpangina, and being >6 years was associated with pain, previous antibiotic treatment and at discharge, and previous NSAID regimen.</p><p><strong>Conclusions: </strong>The analyzed pediatric oral pathologies treated in the emergency department are of mucosal and infectious origin. Dental disease prevail in children >6 years of age and mucosal lesions in those =6 years; no sex differences are observed.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/5b/assn-46-02-e1041.PMC10518804.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10481828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Breastfeeding and rooming-in in the management of neonatal abstinence syndrome. Scoping review].","authors":"Paula Baeza-Gozalo,&nbsp;Sara Sola-Cía,&nbsp;Olga López-Dicastillo","doi":"10.23938/ASSN.1048","DOIUrl":"10.23938/ASSN.1048","url":null,"abstract":"<p><p>At present, more babies are born with neonatal abstinence syndrome due to the increased use of certain substances by their mothers while pregnant. The therapeutic approaches for this syndrome vary in clinical practice, and in some centres, breastfeeding and rooming-in are interrupted. The aim of this work was to analyse the effects of breastfeeding and rooming-in in infants with neonatal abstinence syndrome by conducting a scoping review of the related literature in PubMed and CINAHL. Eleven papers were included, which showed that breastfeeding and rooming-in reduced hospital stay and the need for and duration of pharmacological treatment. In addition, rooming-in decreased the likelihood of admission to the Neonatal Intensive Care Unit, although there was no improvement of the severity of neonatal abstinence syndrome signs. Breastfed infants had milder withdrawal signs and, although they were more likely to be readmitted than formula-fed infants were, there were no statistically significant differences. There was no evidence that rooming-in decreased hospital readmission after discharge. Our findings support the maintenance of cohabitation and breastfeeding whenever possible in the management of this neonatal abstinence syndrome, so as not to worsen the conditions of the neonate, while introducing measures to ensure mother-child safety.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/12/assn-46-02-e1048.PMC10518805.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10492998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Distal ventriculoperitoneal shunt catheter migration into the pulmonary artery: a rare complication].","authors":"Pelayo Hevia-Rodríguez,&nbsp;Mikel Armendariz-Guezala,&nbsp;José Undabeitia-Huertas","doi":"10.23938/ASSN.1046","DOIUrl":"10.23938/ASSN.1046","url":null,"abstract":"<p><p>Ventriculoperitoneal shunt placement is a common treatment for hydrocephalus, although not devoid of complications. We report a case of a 60-year-old male who underwent ventriculoperitoneal shunt implantation for the treatment of post-traumatic hydrocephalus. Thirteen months post- surgery, after an initial clinical improvement, the patient manifested gait and cognitive disorders. Chest X-rays and computed tomography revealed that the distal shunt catheter had migrated into the pulmonary artery. The catheter was removed by reopening the previous retroauricular incision followed by manual traction, without incidents. A new peritoneal catheter was implanted with immediate clinical improvement and no further complications two years after the second surgery. We communicate a rare complication of a standard neurosurgical procedure that can be detected by different healthcare professionals, and review its various forms of presentation and multidisciplinary management strategies from 19 similar clinical cases found in the literature.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/65/assn-46-02-e1046.PMC10507370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10066368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The future of public health after the pandemic. A window of opportunity].","authors":"Salvador Peiró","doi":"10.23938/ASSN.1045","DOIUrl":"10.23938/ASSN.1045","url":null,"abstract":"","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/51/80/assn-46-02-e1045.PMC10507369.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10057288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Survival of cancer patients in Navarre and comparison with Spain].","authors":"Marcela Guevara,&nbsp;Miren Baztan,&nbsp;Rosana Burgui,&nbsp;Alberto Ovies,&nbsp;Aitziber Menéndez,&nbsp;Maribel Eciolaza,&nbsp;Conchi Moreno-Iribas,&nbsp;Eva Ardanaz","doi":"10.23938/ASSN.1042","DOIUrl":"https://doi.org/10.23938/ASSN.1042","url":null,"abstract":"<p><strong>Background: </strong>To analyze the survival of adult cancer patients in Navarre, describe its trend, and compare the data for this Spanish Autonomous Community against that reported for Spain.</p><p><strong>Methods: </strong>Records of adult cancer patients were retrieved from the Navarre´s population-based cancer registry for two periods (1999-2007 and 2008-2016). The vital status had been updated to 2020. Observed survival, net survival and age-standardized net survival at five years with 95% confidence intervals were estimated overall and for twenty-nine cancer groups.</p><p><strong>Results: </strong>We analyzed 57,564 cases. Age-standardized net survival was 59.9% (59.1-60.8) and 63.8% (62.8-64.7) for males and females diagnosed with cancer during the 2008-2016 period, respectively. Age-standardized net survival ranged from 13.4% (10.4-17.4) for pancreatic cancer to 94.0% (88.1-100) for thyroid cancer in male patients, and from 11.9% (7.2-19.7) for liver cancer to 95.6% (92.6-98.6-%) for thyroid cancer in female patients. Compared with cases diagnosed in the 1999-2007 period, age-standardized net survival increased in 10 cancer groups, resulting in an overall increase of 5.1 (4.1-6.0) percentage points. The age-standardized net survival in Navarre was 2.7 (1.9-3.4) percentage points higher than that described for Spain for the 2008-2013 period.</p><p><strong>Conclusions: </strong>In Navarre, the survival of cancer patients diagnosed during the 2008-2016 period improved significantly in comparison to the 1999-2007 period. Different factors may explain this improvement, including earlier diagnoses, more effective treatment options, and better healthcare processes. Overall, survival was higher in women than in men. Our results suggest a higher survival rate in Navarre than in Spain.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/17/52/assn-46-02-e1042.PMC10498136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10603735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk factors for cancer-related cognitive impairment in breast and colorectal cancer patients who undergo chemotherapy].","authors":"Patricia Iranzo,&nbsp;Ana Callejo,&nbsp;Julio Arbej,&nbsp;Sebastian Menao,&nbsp;Dolores Isla,&nbsp;Raquel Andrés","doi":"10.23938/ASSN.1040","DOIUrl":"https://doi.org/10.23938/ASSN.1040","url":null,"abstract":"<p><strong>Background: </strong>Our study aims to evaluate the impact of different factors on cancer-related cognitive impairment in patients who undergo chemotherapy.</p><p><strong>Methodology: </strong>Prospective longitudinal single-centre study that included patients with breast and colon carcinoma who underwent chemotherapy as part of their treatment. Clinical and genetic characteristics of the patients (single nucleotide polymorphisms, SNPs) were collected. Patients' neurocognitive status was assessed using eleven validated tests at three time points: before chemotherapy (M0 - baseline), between one and four weeks after completing chemotherapy (M1), and between 24-30 weeks after completing chemotherapy (M2).</p><p><strong>Results: </strong>Sixty-two patients were included in this study; 82% were female, median age was 56 years (range 30-74), and 64.5% had been diagnosed with breast cancer. Overall, better cognitive results at M0 were associated with age < 55 years, higher educational level, absence of comorbidities, and the CC variant rs471692 (TOP2A). Significant decline was found between M0 to M1 in the Rey Auditory Verbal Learning Test and the Letter and Number test, with evidence of recovery in M2 compared to M0 regarding the following test: Visual Memory, Functioning Assessment Short Test (FAST), Digit Symbol Substitution and Cube. In the multivariate analysis, being =55 years of age, adjuvant chemotherapy, presence of comorbidities, tobacco and alcohol use, and GT variant rs1800795 were associated with cognitive decline between M0 and M1.</p><p><strong>Conclusion: </strong>Being =55 years of age, female, presence of comorbidities and basic education level are related to a higher risk of cognitive impairment after chemotherapy.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/7a/assn-46-02-e1040.PMC10498134.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10603733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Translation and transcultural adaptation of the Person-Centred Practice Inventory Staff (PCPI-S) for health professionals in Spain].","authors":"Begoña Errasti-Ibarrondo,&nbsp;Virginia La Rosa-Salas,&nbsp;Marta Lizarbe-Chocarro,&nbsp;Yvonne Gavela-Ramos,&nbsp;Ana Choperena,&nbsp;Leire Arbea Moreno,&nbsp;Mónica Vázquez-Calatayud,&nbsp;María José Galán-Espinilla,&nbsp;Brendan McCormack,&nbsp;Ana Carvajal-Valcárcel","doi":"10.23938/ASSN.1039","DOIUrl":"https://doi.org/10.23938/ASSN.1039","url":null,"abstract":"<p><strong>Background: </strong>Person-centred practices - following national and international developments in health-care policies - have become a key approach in healthcare. The Person-Centred Practice Inventory - Staff is an instrument based on the theoretical framework Person-Centred Practice that focuses on the staff's perspective and how they experience person-centred practices. Here, the aim of this study is to obtain the first Spanish version of the PCPI-S translated and adapted into the Spanish context.</p><p><strong>Methods: </strong>The translation and adaptation of the instrument followed the Translation and Cultural Adaptation of Patient Reported Outcomes Measures - Principles of Good Practice, which included a consulting session with experts. Content validation measures on clarity and relevance were assessed for every item (I-CVI) and the survey as a whole (S-CVI/Ave).</p><p><strong>Results: </strong>No major difficulties were registered to reach an agreement on the 12 items that needed to be clarified. Regarding clarity and relevance. The validity index per item (I-CVI) obtained excellent scores for clarity in 53 items and for relevance in 59; the S-CVI/Ave showed excellent results (=90).</p><p><strong>Conclusions: </strong>This first version of the Person-Centred Practice Inventory - Staff instrument adapted to the Spanish context is conceptually and semantically equivalent to the original one. This valuable tool will be of great help to identify the perception of healthcare professionals on person-centred practices.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/f8/assn-46-02-e1039.PMC10498133.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10603736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}