{"title":"Reflux symptoms in patients with mini gastric bypass-one anastomotic bypass (MGB-OAGB) after failed laparoscopic gastric banding (LAGB) - Long-term follow-up and therapeutic options","authors":"Ingeborg Bohlmann, Werner Müller, Claudius Falch","doi":"10.1016/j.amjsurg.2026.116893","DOIUrl":"10.1016/j.amjsurg.2026.116893","url":null,"abstract":"<div><h3>Background</h3><div>Reflux after Mini-Gastric-Bypass - One-Anastomosis-Gastric-Bypass (MGB-OAGB) is well documented. Although uncommon after primary MGB-OAGB, affected patients may experience a significant reduction in quality of life.</div><div>In this study we provide a clinical evaluation of long-term, recurrent reflux symptoms and their impact on daily life in patients who underwent revisional OAGB-MGB after failed laparoscopic gastric banding (LAGB). The median follow-up period was 13 years.</div></div><div><h3>Material and methods</h3><div>From March 2004 to February 2008 18 patients underwent a revisional MGB-OAGB after failure of LAGB. The main reasons for LAGB failure were penetration, slipping, repeated leakage, intolerance, insufficient weight loss/weight regain. The MGB-OAGB was performed according to Robert Rutledge, the procedure was carried out as a one-step surgery.</div><div>In 2017 we conducted a telephone survey with a median of 13 years after revision to MGB-OAGB. We used the standardized GERD- Health Related Quality of Life Questionnaire (GERD-HRQL).</div></div><div><h3>Results</h3><div>We could reach out to 15 of the 18 patients. The maximum score of the GERD-HRQL is 30, the cut-off for severe reflux symptoms is 12 points. 2/3 of our patients showed a score considerably above 12 points.</div><div>Approximately 1/3 of the patients above had to go through a second revision surgery to RYGB.</div></div><div><h3>Conclusion</h3><div>Based on the results of our survey and clinical symptoms we discontinued to use MGB-OAGB as a revisional option after LAGB. The outcome of this highly selective group of patients cannot be generally applied to revisional bariatric surgery.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"256 ","pages":"Article 116893"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniella Hui Xin Poh , Cristal Li Yi Tan , Yaoyi Ng , Kevin Xiang Zhou , Qin Xiang Ng , Serene Si Ning Goh
{"title":"Active surveillance for low-grade ductal carcinoma in situ: A mixed-methods systematic review of patient, clinician, and health-system perspectives","authors":"Daniella Hui Xin Poh , Cristal Li Yi Tan , Yaoyi Ng , Kevin Xiang Zhou , Qin Xiang Ng , Serene Si Ning Goh","doi":"10.1016/j.amjsurg.2026.116898","DOIUrl":"10.1016/j.amjsurg.2026.116898","url":null,"abstract":"<div><h3>Background</h3><div>Low-grade ductal carcinoma in situ (DCIS) is increasingly detected through breast screening, raising concerns about overtreatment. Active surveillance (AS) has emerged as an alternative to immediate surgery. We synthesized patient, clinician, and health-system perspectives relevant to AS adoption.</div></div><div><h3>Methods</h3><div>We conducted a mixed-methods systematic review (MMSR) following PRISMA, integrating quantitative, qualitative, and mixed-methods studies using a convergent integrated synthesis approach (PROSPERO CRD420250656621). PubMed, Embase, and the Cochrane Library were searched from 2000 to 2025. Risk of bias (RoB) was assessed using standardized tools.</div></div><div><h3>Results</h3><div>Fourteen studies were included. Patient preferences varied widely and were influenced by anxiety, terminology, perceived risk, and trust. Clinicians highlighted concerns about progression risk, pathology variability, medicolegal exposure, and limited long-term evidence. Institutional readiness was constrained by gaps in surveillance pathways, risk-stratification tools, and implementation support. Overall RoB was low to moderate.</div></div><div><h3>Conclusion</h3><div>Adoption of AS for low-grade DCIS depends not only on clinical evidence but also on psychological, communication, and organizational factors that shape decision-making across patients, clinicians, and health systems.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"256 ","pages":"Article 116898"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannah Palmerton , Brooklyn Williams , Grace Pak , Bobby Zhang , Beau Prey , Andrew Francis , James Williams , Luke Pumiglia , Erik Roedel , Mike Lallemand , John McClellan , Nicholas Ieronimakis , Jason Bingham
{"title":"Investigating optimal warming techniques for hypothermia in a swine model of ischemia","authors":"Hannah Palmerton , Brooklyn Williams , Grace Pak , Bobby Zhang , Beau Prey , Andrew Francis , James Williams , Luke Pumiglia , Erik Roedel , Mike Lallemand , John McClellan , Nicholas Ieronimakis , Jason Bingham","doi":"10.1016/j.amjsurg.2026.116912","DOIUrl":"10.1016/j.amjsurg.2026.116912","url":null,"abstract":"<div><h3>Introduction</h3><div>With trauma, hypothermia is associated with increased bleeding and worse outcomes yet the pace of rewarming is unproven and its influence unclear. We hypothesized that the rate of rewarming influences outcomes and evaluated its impact in a porcine model of trauma.</div></div><div><h3>Methods</h3><div>Pigs underwent controlled hemorrhage and hypothermia to 32 °C for 1 h, followed by rapid or slow rewarming for 3 h. Hemodynamics and coagulation were compared along with liver gene expression.</div></div><div><h3>Results</h3><div>The mean temperature reached between fast (37.9±0.13 °C) and slow groups (34.5±1.2 °C) was significantly different (p < 0.01). The slow group had a lower heart rate and the mean arterial pressure (MAP) was lower with both slow and fast. No major differences in lactate, pH, coagulation or gene expression were observed.</div></div><div><h3>Conclusion</h3><div>Our study supports rapid rewarming for reversing hypothermia post hemorrhage. Further research is needed to evaluate long-term outcomes within clinical settings.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"256 ","pages":"Article 116912"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Axillary lymph node dissection is not routinely indicated in patients with sentinel lymph node residual micrometastases following neoadjuvant systemic therapy","authors":"Kinan Mokbel , Kefah Mokbel","doi":"10.1016/j.amjsurg.2026.116901","DOIUrl":"10.1016/j.amjsurg.2026.116901","url":null,"abstract":"<div><h3>Background</h3><div>The clinical relevance of residual micrometastatic nodal disease (ypN1mi) detected in the sentinel lymph node (SLN) or following targeted axillary dissection (TAD) after neoadjuvant systemic therapy (NST) remains uncertain, particularly regarding the need for completion axillary lymph node dissection (cALND).</div></div><div><h3>Methods</h3><div>This narrative review summarizes evidence from registry-based and international cohort studies evaluating axillary recurrence and oncological outcomes in patients with ypN1mi managed with or without cALND after NST.</div></div><div><h3>Results</h3><div>Analyses from the SEER registry and the OPBC-07/microNAC cohort demonstrate a low incidence of axillary recurrence and no significant differences in oncological outcomes between SLNB alone and cALND. In subgroup analyses of triple-negative breast cancer, microNAC reported lower axillary recurrence rates with cALND; however, no difference in invasive recurrence was observed between groups.</div></div><div><h3>Conclusions</h3><div>Routine cALND appears unnecessary in most patients with ypN1mi after NST. Future studies should evaluate whether regional nodal irradiation can also be safely omitted.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"256 ","pages":"Article 116901"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Guo , Michael Budu , Jason Trigg , Tian Shen , Robert Hogg , Sam M. Wiseman
{"title":"Patients living with HIV in the modern era: Postoperative outcomes and healthcare utilization","authors":"Michael Guo , Michael Budu , Jason Trigg , Tian Shen , Robert Hogg , Sam M. Wiseman","doi":"10.1016/j.amjsurg.2026.116918","DOIUrl":"10.1016/j.amjsurg.2026.116918","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite advances in antiretroviral therapy (ART), surgical outcomes in people with HIV (PWH) remain poorly understood. This study compared postoperative outcomes and healthcare use between PWH and matched people without HIV (non-PWH) undergoing general surgery in British Columbia, Canada.</div></div><div><h3>Methods</h3><div>Linked HIV-related and health administrative data (Jan 2008–Mar 2020) identified PWH and matched non-PWH. Outcomes included 30-day readmissions, 30-day re-operations, 30-day mortality, one-year mortality, and healthcare utilization.</div></div><div><h3>Results</h3><div>Among 1252 PWH and 5008 non-PWH, HIV status was not associated with odds of 30-day readmissions, re-operations, or deaths. However, PWH had higher odds of mortality within one year post op (OR 1.75, 95% CI: 1.12–2.73), shorter hospital stays (RR 0.64, 95% CI: 0.55–0.73), higher likelihood of lab (RR 2.11, 95% CI: 1.86–2.39), and specialist visits (RR 1.16, 95% CI: 1.01–1.35) compared to non-PWH.</div></div><div><h3>Conclusion</h3><div>PWH experienced similar short-term outcomes but higher one-year mortality and distinct care patterns, suggesting factors beyond perioperative care influence outcomes.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"256 ","pages":"Article 116918"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abolfazl Salari, Mengyuan Ruan, Terhas Weldeslase, Jiping Wang, Joel S Weissman, George Molina
{"title":"Association of hospital quality and social determinants of health with short-term surgical outcomes among medicare beneficiary patients undergoing elective cancer surgery.","authors":"Abolfazl Salari, Mengyuan Ruan, Terhas Weldeslase, Jiping Wang, Joel S Weissman, George Molina","doi":"10.1016/j.amjsurg.2026.117071","DOIUrl":"10.1016/j.amjsurg.2026.117071","url":null,"abstract":"<p><strong>Background: </strong>Community-level sociodemographic factors and hospital quality are associated with access to cancer care and outcomes.</p><p><strong>Methods: </strong>Using Medicare data (2016-2018), we evaluated the association between social determinants of health (SDoH) and hospital quality with 30-day mortality and readmission after selected elective cancer surgery. Separate multivariable logistic regression models sequentially adjusted for comorbidities and SDoH factors (Social Vulnerability Index (SVI) and Distressed Communities Index (DCI)) and then Hospital Star Rating.</p><p><strong>Results: </strong>Among 16,869 patients, the \"At Risk\" DCI group and higher SVI were associated with higher 30-day mortality, and higher SVI was associated with higher odds of 30-day readmission and mortality. Subsequent models demonstrated that higher Hospital Star Rating was associated with lower odds of 30-day mortality and readmission and SDoH factors lost significance after adjusting for Hospital Star Rating.</p><p><strong>Conclusions: </strong>Hospital quality may have a greater impact on short-term outcomes than SDoH factors.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"117071"},"PeriodicalIF":2.3,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13340753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148161508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie Delos Santos , Marta Invernizzi , Cindy Liu , Xin Tong , Jodi Rosen , Lihong V. Wang , Lily L. Lai
{"title":"Utilizing post-imaging surveys to guide development of photoacoustic computed technology for breast imaging","authors":"Stephanie Delos Santos , Marta Invernizzi , Cindy Liu , Xin Tong , Jodi Rosen , Lihong V. Wang , Lily L. Lai","doi":"10.1016/j.amjsurg.2026.116828","DOIUrl":"10.1016/j.amjsurg.2026.116828","url":null,"abstract":"<div><h3>Objective</h3><div>Current breast imaging has limitations. Mammography uses radiation and compression; ultrasound depends on user expertise; MRI requires time and intravenous contrast. Development of novel technologies for breast imaging may be improved with patient surveys.</div></div><div><h3>Methods</h3><div>Breast cancer patients scheduled for breast operations or undergoing neoadjuvant therapy were enrolled in studies to evaluate photoacoustic computed tomography (PACT) at a single institution. After each imaging session, the patients were surveyed. The survey included Likert scale, multiple choice, and open-ended questions.</div></div><div><h3>Results</h3><div>Of 49 patients, 86 % completed at least one survey with 42 % completing three. Survey completion took <10 min. Features assessed specific to the imaging technology included water bath, duration, positioning, and environment. Patients overwhelmingly reported ease of PACT over mammography and MRI. Suggestions included better cushioning, improved head support, well-fitting laser safety glasses.</div></div><div><h3>Conclusion</h3><div>Photoacoustic breast imaging is feasible to breast cancer patients. User feedback informs on clinical technology improvement.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"254 ","pages":"Article 116828"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146036385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jasmine Zhang , Janice J. Wong , Terrance Peng , Yifan V. Mao , Elena G. Hughes , Anna M. Sawka , Masha J. Livhits , Michael W. Yeh , James X. Wu
{"title":"Chinese language patients’ perceptions on thyroid disease and treatment: A qualitative study","authors":"Jasmine Zhang , Janice J. Wong , Terrance Peng , Yifan V. Mao , Elena G. Hughes , Anna M. Sawka , Masha J. Livhits , Michael W. Yeh , James X. Wu","doi":"10.1016/j.amjsurg.2026.116842","DOIUrl":"10.1016/j.amjsurg.2026.116842","url":null,"abstract":"<div><h3>Background</h3><div>Chinese language speakers comprise a significant proportion of the United States patient population. This qualitative study seeks to characterize health beliefs among Chinese-speaking patients with thyroid disease to inform culturally competent care.</div></div><div><h3>Methods</h3><div>Thirteen Chinese-speaking patients (mean age 47; 12 female) participated in semi-structured interviews exploring beliefs about thyroid disease and its management.</div></div><div><h3>Results</h3><div>Participants reported limited knowledge of thyroid disease and desired more accessible education. Thyroid disease was viewed as minimally disruptive relative to other diseases or malignancies with family history, environmental exposures, and stress as contributors to development. Experiences with conventional thyroid treatment were marked by logistical and relational challenges. While modern medicine was seen as effective, some perceived it to be overly aggressive and believed Traditional Chinese Medicine (TCM) may have a valuable, complementary role in management.</div></div><div><h3>Conclusions</h3><div>Future research may seek to investigate the integration of TCM and conventional thyroid care to improve therapeutic relationships and health outcomes for Chinese-language patients.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"254 ","pages":"Article 116842"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaspinder Sanghera , Ioannis Liapis , Nritya Nair , Michelle Holland , Manish Tripathi , Larry Hearld , Krista Mehari , Smita Bhatia , Annabelle L. Fonseca
{"title":"Examining health system stakeholder-reported barriers and solutions to foregut cancer care","authors":"Jaspinder Sanghera , Ioannis Liapis , Nritya Nair , Michelle Holland , Manish Tripathi , Larry Hearld , Krista Mehari , Smita Bhatia , Annabelle L. Fonseca","doi":"10.1016/j.amjsurg.2026.116824","DOIUrl":"10.1016/j.amjsurg.2026.116824","url":null,"abstract":"<div><h3>Purpose</h3><div>Many patients with foregut cancers fail to receive guideline-concordant treatment. The perspectives of health system stakeholders who care for these patients, and their insights into feasible solutions, remain underexplored.</div></div><div><h3>Methods</h3><div>Using grounded theory methodology, 12 semi-structured interviews were conducted to identify multilevel barriers, and health system stakeholders proposed solutions to overcome these barriers.</div></div><div><h3>Results</h3><div>Participants described barriers across four levels. Individual-level barriers included financial toxicity, transportation challenges, and psychosocial distress. Provider-level barriers included inadequate physician-patient communication and insufficient inter-provider communication. Institutional barriers included delays in accessing specialty care, scheduling inefficiencies, and institutional resource limitations. Policy-level barriers included care fragmentation, inadequate sub-specialty care in rural areas, and inadequate reimbursement. Proposed solutions included strengthening institutional psychiatric support programs, increasing inter-provider engagement, streamlining referral pathways, targeted rural physician recruitment, and reimbursement reform.</div></div><div><h3>Conclusion</h3><div>Health system stakeholders proposed interventions emphasizing communication, navigation, and system-level integration that may improve the delivery of foregut cancer care in resource-constrained environments.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"254 ","pages":"Article 116824"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One of the good ones","authors":"Arnav Mahajan","doi":"10.1016/j.amjsurg.2026.116846","DOIUrl":"10.1016/j.amjsurg.2026.116846","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"254 ","pages":"Article 116846"},"PeriodicalIF":2.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}