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Targeted diagnosis and therapy最新文献

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Multicenter clinical trial of 111In-CYT-103 in patients with ovarian cancer. 111In-CYT-103在卵巢癌患者中的多中心临床试验。
Targeted diagnosis and therapy Pub Date : 1992-01-01
D G Gallup
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引用次数: 0
Generation and characterization of monoclonal antibody B72.3. Experimental and preclinical studies. 单克隆抗体B72.3的制备与鉴定。实验和临床前研究。
Targeted diagnosis and therapy Pub Date : 1992-01-01
D M Colcher, D E Milenic, J Schlom
{"title":"Generation and characterization of monoclonal antibody B72.3. Experimental and preclinical studies.","authors":"D M Colcher, D E Milenic, J Schlom","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"6 ","pages":"23-44"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12743614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protein engineering strategies. 蛋白质工程策略。
Targeted diagnosis and therapy Pub Date : 1992-01-01
M Whitlow
{"title":"Protein engineering strategies.","authors":"M Whitlow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"7 ","pages":"55-61"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12799213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular cloning of ricin. 蓖麻毒素的分子克隆。
Targeted diagnosis and therapy Pub Date : 1992-01-01
L M Roberts, J W Tregear, J M Lord
{"title":"Molecular cloning of ricin.","authors":"L M Roberts,&nbsp;J W Tregear,&nbsp;J M Lord","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A variety of strategies have been used to obtain cDNA and genomic clones encoding ricin. Since their isolation these sequences have been manipulated to allow expression of A chain (19) and A chain mutants (15,20,34), B chain (14,21-23) and proricin (24). Utilizing structural information (35), precise changes have been introduced into both A and B chains with the aim of probing catalytic and sugar-binding residues, respectively. In the longer term, such manipulations, coupled with successful expression and purification schemes, will allow the delineation of functional residues and domains, ensuring that ricin remains the prototype plant toxin with which to study cellular intoxication and ribosome inactivation and to utilize in pharmaceutical product development.</p>","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"7 ","pages":"81-97"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12799215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical and genetic characterization of the enzymatic activity associated with ricin A chain. 与蓖麻毒素A链相关的酶活性的化学和遗传特性。
Targeted diagnosis and therapy Pub Date : 1992-01-01
L Greenfield
{"title":"Chemical and genetic characterization of the enzymatic activity associated with ricin A chain.","authors":"L Greenfield","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"7 ","pages":"151-82"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12799966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The structure of Pseudomonas exotoxin A as a guide to rational design. 假单胞菌外毒素 A 的结构是合理设计的指南。
Targeted diagnosis and therapy Pub Date : 1992-01-01
P J Nicholls, R J Youle
{"title":"The structure of Pseudomonas exotoxin A as a guide to rational design.","authors":"P J Nicholls, R J Youle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"7 ","pages":"439-46"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12799983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diphtheria toxin expression in Escherichia coli. 白喉毒素在大肠杆菌中的表达。
Targeted diagnosis and therapy Pub Date : 1992-01-01 DOI: 10.1201/9781003066651-16
L. Greenfield
{"title":"Diphtheria toxin expression in Escherichia coli.","authors":"L. Greenfield","doi":"10.1201/9781003066651-16","DOIUrl":"https://doi.org/10.1201/9781003066651-16","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"1 1","pages":"307-38"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65951678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of growth factor-toxin fusion proteins. 生长因子-毒素融合蛋白的表达。
Targeted diagnosis and therapy Pub Date : 1992-01-01 DOI: 10.1201/9781003066651-22
G. Edwards, D. Defeo-jones, S. Stirdivant, D. Heimbrook, A. Oliff
{"title":"Expression of growth factor-toxin fusion proteins.","authors":"G. Edwards, D. Defeo-jones, S. Stirdivant, D. Heimbrook, A. Oliff","doi":"10.1201/9781003066651-22","DOIUrl":"https://doi.org/10.1201/9781003066651-22","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"7 1","pages":"425-37"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65951804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OncoScint CR103 imaging in the surgical management of patients with colorectal cancer. OncoScint CR103成像在结直肠癌患者手术治疗中的应用。
Targeted diagnosis and therapy Pub Date : 1992-01-01
R J Doerr, H H Abdel-Nabi
{"title":"OncoScint CR103 imaging in the surgical management of patients with colorectal cancer.","authors":"R J Doerr,&nbsp;H H Abdel-Nabi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"6 ","pages":"89-109"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12743618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future directions in tumor radioimmunodetection. 肿瘤放射免疫检测的未来方向。
Targeted diagnosis and therapy Pub Date : 1992-01-01
T J McKearn
{"title":"Future directions in tumor radioimmunodetection.","authors":"T J McKearn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"6 ","pages":"211-32"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12743613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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