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Targeted diagnosis and therapy最新文献

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Targeted therapeutic systems. 靶向治疗系统。
Targeted diagnosis and therapy Pub Date : 1990-01-01
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引用次数: 0
Drug-immunoglobulin conjugates as targeted therapeutic systems. 药物-免疫球蛋白偶联物作为靶向治疗系统。
Targeted diagnosis and therapy Pub Date : 1990-01-01
A K Mitra, M K Ghosh
{"title":"Drug-immunoglobulin conjugates as targeted therapeutic systems.","authors":"A K Mitra, M K Ghosh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"141-87"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current status of antibody-toxin conjugates for tumor therapy. 抗体-毒素结合物在肿瘤治疗中的现状。
Targeted diagnosis and therapy Pub Date : 1990-01-01
S Ramakrishnan
{"title":"Current status of antibody-toxin conjugates for tumor therapy.","authors":"S Ramakrishnan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"189-213"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From monoclonal antibodies to immunonanospheres in the pharmaceutical sciences. 从单克隆抗体到药物科学中的免疫微球。
Targeted diagnosis and therapy Pub Date : 1990-01-01
A P Rolland, D Bourel
{"title":"From monoclonal antibodies to immunonanospheres in the pharmaceutical sciences.","authors":"A P Rolland, D Bourel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"259-88"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal antibodies, immunoconjugates, and liposomes as targeted therapeutic systems. 单克隆抗体、免疫偶联物和脂质体作为靶向治疗系统。
Targeted diagnosis and therapy Pub Date : 1990-01-01
P Tyle, B P Ram
{"title":"Monoclonal antibodies, immunoconjugates, and liposomes as targeted therapeutic systems.","authors":"P Tyle, B P Ram","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"3-22"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemistry and biology of immunotargeted liposomes. 免疫靶向脂质体的化学和生物学研究。
Targeted diagnosis and therapy Pub Date : 1990-01-01
A L Weiner
{"title":"Chemistry and biology of immunotargeted liposomes.","authors":"A L Weiner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"305-36"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New trends in the use of radioimmunoconjugates for the therapy of cancer. 放射免疫偶联物治疗癌症的新趋势。
Targeted diagnosis and therapy Pub Date : 1990-01-01
D J Buchsbaum, T S Lawrence
{"title":"New trends in the use of radioimmunoconjugates for the therapy of cancer.","authors":"D J Buchsbaum,&nbsp;T S Lawrence","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since 1980, there has been intense research in the area of radiolabeled immunoconjugates for the localization and therapy of cancer in both experimental animal models and in humans. This is based on the potential of MoAbs reactive with tumor-associated antigens as specific carriers of radionuclides, toxins, and chemotherapeutic drugs. Even though there has been much progress, a great deal of work and innovation will be required before the use of radiolabeled immunoconjugates becomes an established method for clinical tumor detection and therapy. The greatest problem is the relatively low tumor uptake of radiolabeled MoAbs in humans. This results in relatively high background levels of radioactivity in normal tissues and insufficient radioactivity in the tumor for the detection of small lesions and for therapeutic efficacy. In the future, one can expect the development of new MoAbs with greater specificity for particular tumor types, improvements in radiolabeling procedures, and the use of more effective nuclides than 131I. Biological, physiological, pathological, and dosimetric considerations need to be addressed in detail. With this additional information, it is hoped that the full potential for radiolabeled immunoconjugates will be realized.</p>","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"215-55"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of hollow-fiber bioreactor systems for large-scale production of murine monoclonal antibodies. 大规模生产小鼠单克隆抗体的中空纤维生物反应器系统的评价。
Targeted diagnosis and therapy Pub Date : 1990-01-01
T L Evans, R A Miller
{"title":"Evaluation of hollow-fiber bioreactor systems for large-scale production of murine monoclonal antibodies.","authors":"T L Evans,&nbsp;R A Miller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"25-43"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liposomes as carriers for antibiotics. 脂质体作为抗生素的载体。
Targeted diagnosis and therapy Pub Date : 1990-01-01
M C Nacucchio, P H Di Rocco, D O Sordelli
{"title":"Liposomes as carriers for antibiotics.","authors":"M C Nacucchio,&nbsp;P H Di Rocco,&nbsp;D O Sordelli","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"337-54"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoconjugates in drug delivery systems. 药物传递系统中的免疫偶联物。
Targeted diagnosis and therapy Pub Date : 1990-01-01
J B Cannon, H W Hui
{"title":"Immunoconjugates in drug delivery systems.","authors":"J B Cannon,&nbsp;H W Hui","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77632,"journal":{"name":"Targeted diagnosis and therapy","volume":"3 ","pages":"121-39"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13286282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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