American Journal on Addictions最新文献

{"title":"Treatment patterns and healthcare resource use among veterans initiating medication for incident moderate-to-severe alcohol use disorder","authors":"Regina Grebla PhD,&nbsp;Teresa L. Kauf PhD,&nbsp;Angela Lax MPH,&nbsp;Erin E. Cook MPH, ScD,&nbsp;Yilu Lin MPH, PhD,&nbsp;Jieruo Liu PhD,&nbsp;Shuqian Liu MD,&nbsp;Amy K. O'Sullivan PhD,&nbsp;Lizheng Shi MA, MsPharm, PhD,&nbsp;Sherry Shi MS,&nbsp;Maria A. Sullivan MD, PhD,&nbsp;Elyse Swallow MA, MPP,&nbsp;Katie Witkiewitz PhD,&nbsp;Karen Drexler MD","doi":"10.1111/ajad.70036","DOIUrl":"10.1111/ajad.70036","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Several medications for alcohol use disorder (MAUDs) are recommended to treat alcohol use disorder (AUD) in the Veterans Affairs (VA) guidelines. This study descriptively characterized treatment patterns and healthcare resource utilization (HCRU) among VA patients with AUD treated with VA-recommended MAUDs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Veterans Health Administration data (VHA; 08/01/2013–11/30/2019) were used to identify 31,384 adults aged ≥18 years with AUD who initiated disulfiram (<i>n</i> = 2115), acamprosate (<i>n</i> = 3756), oral naltrexone (<i>n</i> = 25,082), or extended-release naltrexone (XR-NTX; <i>n</i> = 431) following AUD diagnosis. Study measures, stratified by medication received, included treatment adherence (proportion of days covered), discontinuation, and HCRU over 1 year.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean time to treatment discontinuation was high for all MAUDs but longest for XR-NTX (92 vs. 55–59 days; all <i>p</i> &lt; .001). Relative to the year preceding AUD diagnosis, treatment with MAUDs was associated with fewer hospitalizations (XR-NTX: 0.48 vs. 0.42; oral naltrexone: 0.58 vs. 0.47; acamprosate: 0.67 vs. 0.60; disulfiram: 0.63 vs. 0.57) and more outpatient visits per patient (XR-NTX: 20.0 vs. 36.0; oral naltrexone: 19.0 vs. 30.0; acamprosate: 19.0 vs. 31.0; disulfiram: 17.0 vs. 29.0).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Among veterans with AUD, this descriptive analysis found that MAUD use was associated with reduced hospitalizations, and XR-NTX was associated with a longer treatment duration versus oral MAUDs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>This real-world study is among the first to describe clinical characteristics, treatment patterns, and HCRU in VHA patients who initiated MAUDs when all MAUDs were included in the VHA formulary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 5","pages":"536-546"},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between cannabis use and suicidal intensity in psychiatric inpatients","authors":"Adeolu Funso Oladunjoye MD, MPH,&nbsp;Alan Swann MD,&nbsp;Thomas R. Kosten MD,&nbsp;Michelle Patriquin PhD,&nbsp;Tim Bigdeli PhD,&nbsp;Peter Barr PhD,&nbsp;Anna V. Wilkinson PhD,&nbsp;Mark J. Harding BA,&nbsp;David A. Nielsen PhD,&nbsp;David P. Graham MD","doi":"10.1111/ajad.70047","DOIUrl":"10.1111/ajad.70047","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Over the past 15 years, most states have legalized the medical use of cannabis. Since then, daily use nearly tripled while the number of adults dying by suicide increased by 31%. Key studies found a greater suicidal intensity associated with cannabis use (CU) in adolescents. Adult associations have been understudied. The purpose of this study was to evaluate associations between CU and suicidal ideation intensity (SII) in adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We examined 530 psychiatric inpatients ages 18 and above using the Columbia-Suicide Severity Rating Scale and the Alcohol, Smoking and Substance Involvement Screening Test for CU. We conducted a path analysis model of moderating and mediating factors, including psychiatric comorbidity, emotional regulation, psychological flexibility, and polygenic risk scores for externalization, CU, and suicide.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Sixteen percent of the participants had no suicidality, 34.3% reported suicidal ideation, and 49.6% reported a prior suicide attempt. CU was found to be associated with lower risk of SII for females (<i>p</i> = .026) but not for males (<i>p</i> = .525), and increased CU was associated with greater risk of SII with lower psychological flexibility in males (<i>p</i> = .049) but not females (<i>p</i> = .628).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CU was associated with increased SII among psychiatric inpatients, with sex-specific patterns and potential mediation by psychological flexibility. Further studies exploring specific amounts, duration of use, and time frames of CU during adolescence and adulthood may provide insights into its associated risks, especially as legalization expands.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific significance</h3>\u0000 \u0000 <p>Patterns of past and current CU may increase understanding of mechanisms predicting increased SII in adult male psychiatric inpatients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 5","pages":"506-516"},"PeriodicalIF":1.9,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of the complex intersection between religion, spirituality, and harm reduction","authors":"Jessica Van Denend MDiv, PhD,&nbsp;Jeremy Weleff DO,&nbsp;Kelly Park MD,&nbsp;Oriana Mayorga MDiv,&nbsp;M. Gabriela Garcia-Vassallo MD","doi":"10.1111/ajad.70046","DOIUrl":"10.1111/ajad.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Within substance use research, religion and spirituality (r/s) have been understudied in relation to harm reduction approaches. We perform a literature review to characterize various intersections between r/s and harm reduction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We searched major databases, Google Scholar, and other sources for academic articles and gray literature on the intersection between r/s and harm reduction. We describe areas of overlap and tension as well as analyze the results using three tiers of proximity to lived/living experience.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 457 papers identified, 169 met final inclusion. Of these, 100 papers contained discussion of alignment between religious or spiritual values and harm reduction values, 39 discussed strategic uses of religious or spiritual resources, 22 discussed harm reduction practices in relation to substances with religious/spiritual relevance, such as psychedelics, and 8 discussed religious/spiritual support for harm reduction workers. Eighteen noted that content was coproduced with persons with lived/living experience, 75 of them noted content was informed by relationship with persons with lived/living experience, and in 76 no such engagement was mentioned.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>The relevance of r/s is not limited to abstinence-based models and has significance in the harm reduction literature.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>This is the first systematic study of the complex intersection between r/s and harm reduction. The results point to opportunities to further understand r/s as both barrier to and resource for harm reduction efforts, as well as how proximity to those with lived/living experience may influence alignment with harm reduction values.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 5","pages":"495-505"},"PeriodicalIF":1.9,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Report: Effectiveness of two financial incentives on patient follow-up after brief substance use disorder inpatient treatment","authors":"Mia A. Haidamus BA,&nbsp;Leah A. Majumder BA,&nbsp;Adriana Chen BA,&nbsp;Margaret L. Griffin PhD,&nbsp;Scott E. Provost MM, MSW,&nbsp;Roger D. Weiss MD,&nbsp;R. Kathryn McHugh PhD","doi":"10.1111/ajad.70045","DOIUrl":"10.1111/ajad.70045","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Clinical follow-up data after substance use disorder (SUD) treatment provides important information about treatment effectiveness, yet compliance is a challenge. We compared financial incentives for obtaining follow-up data from adults receiving inpatient SUD treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants (<i>N</i> = 237) were randomized to receive a guaranteed incentive, raffle-based incentive, or no incentive for completing a 1-month follow-up assessment.</p>\u0000 \u0000 <p>Logistic regression tested the effect of incentives on follow-up completion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Those in the raffle condition had &gt;2 times higher odds of completing a follow-up assessment compared to those in the no-incentive or guaranteed-incentive conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>The raffle-based financial incentive was most effective in obtaining follow-up data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>Raffle-based incentives may improve follow-up after treatment and help clinicians evaluate SUD treatment outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 5","pages":"567-570"},"PeriodicalIF":1.9,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AAAP Podcast Highlight - Addiction Psychiatry Fellowships","authors":"","doi":"10.1111/ajad.70041","DOIUrl":"https://doi.org/10.1111/ajad.70041","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 3","pages":"372"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Become an AAAP Member","authors":"","doi":"10.1111/ajad.70044","DOIUrl":"https://doi.org/10.1111/ajad.70044","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 3","pages":"375"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addiction Psychiatry Advanced Psychotherapy Curriculum","authors":"","doi":"10.1111/ajad.70042","DOIUrl":"https://doi.org/10.1111/ajad.70042","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 3","pages":"373"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 AAAP Annual Meeting Abstract Submissions Open!","authors":"","doi":"10.1111/ajad.70043","DOIUrl":"https://doi.org/10.1111/ajad.70043","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 3","pages":"374"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain intensity in patients using extended-release naltrexone or opioid agonists and its effect on extended-release naltrexone treatment outcomes","authors":"Farid Juya MD,&nbsp;Kristin K. Solli MSc, PhD,&nbsp;Line Holtan BSN,&nbsp;Ann-Christin Sannes MSc, PhD,&nbsp;Bente Weimand MSc, PhD,&nbsp;Anne G. Sagen MSc,&nbsp;Jūratė Š. Benth PhD,&nbsp;Johannes Gjerstad PhD,&nbsp;Lars Tanum MD, DMSci,&nbsp;Jon Mordal MD, PhD","doi":"10.1111/ajad.70035","DOIUrl":"10.1111/ajad.70035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Extended-release naltrexone (XR-NTX) is an opioid antagonist effective for treating opioid use disorder (OUD). However, concerns about inadequate pain management may limit its use. This study will examine changes in pain intensity in OUD patients choosing XR-NTX compared to opioid agonist treatment (OAT), identify subgroups with distinct pain intensity trajectories, and assess the effect of pain intensity on XR-NTX treatment outcomes (retention, relapse, opioid use, and cravings).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This 24-week study included OUD patients aged 18–65 years opting for XR-NTX (<i>n</i> = 160). Patients receiving OAT (<i>n</i> = 151) served as controls. Pain intensity was measured every 4 weeks for XR-NTX and at baseline and Week 24 for OAT using the numerical pain rating scale-11 (NPRS-11). Data were analyzed with linear mixed models and group-based trajectory modeling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between baseline and Week 24, XR-NTX participants with low to moderate pain showed a significant reduction in pain intensity, while those with high pain did not. In the OAT group, no significant reduction in pain intensity was observed (from baseline to Week 24). Pain intensity was not associated with XR-NTX treatment outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Contrary to perception, XR-NTX does not worsen pain intensity, nor did pain intensity affect XR-NTX treatment outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Scientific Significance</h3>\u0000 \u0000 <p>This study is the first to explore the association between changes in pain intensity and XR-NTX treatment outcomes in OUD patients over a 24-week period. The findings challenge the perception that XR-NTX is less suitable for treating OUD patients with pain.</p>\u0000 </section>\u0000 </div>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 5","pages":"528-535"},"PeriodicalIF":1.9,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call for Review Papers 2025","authors":"","doi":"10.1111/ajad.70037","DOIUrl":"https://doi.org/10.1111/ajad.70037","url":null,"abstract":"<p>Click on the PDF file for live links</p><p></p>","PeriodicalId":7762,"journal":{"name":"American Journal on Addictions","volume":"34 3","pages":"368"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajad.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143880097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}