Progress in AIDS pathology最新文献_第2页

The lymph node in AIDS: a light microscopic and ultrastructural study. 艾滋病患者淋巴结的光镜和超微结构研究。

Progress in AIDS pathology Pub Date : 1990-01-01

R A Schinella, W D Muller, M A Greco

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Some facets of cryptosporidiosis. 隐孢子虫病的一些方面。

Progress in AIDS pathology Pub Date : 1990-01-01

B C Anderson

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Bone marrow findings in HIV infection: a pathological study. HIV感染的骨髓发现:一项病理研究。

Progress in AIDS pathology Pub Date : 1990-01-01

C Marche, W Tabbara, C Michon, B Clair, F Bricaire, L Matthiessen

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Diagnostic yields of surgical specimens from patients with AIDS or at risk for AIDS. 来自艾滋病患者或有艾滋病危险的患者的手术标本的诊断结果。

Progress in AIDS pathology Pub Date : 1990-01-01

M Vazquez, H Rotterdam, E Vamvakas

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Lymph nodes in HIV-positive drug abusers with persistent generalized lymphadenopathy: histology, immunohistochemistry, and pathogenetic correlations. hiv阳性药物滥用者伴持续性全身性淋巴结病的淋巴结:组织学、免疫组织化学和发病相关性

Progress in AIDS pathology Pub Date : 1990-01-01

C D Baroni, S Uccini

{"title":"Lymph nodes in HIV-positive drug abusers with persistent generalized lymphadenopathy: histology, immunohistochemistry, and pathogenetic correlations.","authors":"C D Baroni, S Uccini","doi":"","DOIUrl":"","url":null,"abstract":"Persistent generalized lymphadenopathy (PGL) represents an important aspect of the natural history of AIDS. It is a reactive lymphadenitis appearing in HIV-positive drug abusers and homosexual men, involving lymph nodes mostly located in the neck and in axillary regions. This present review chapter describes the most salient histological and immunohistochemical features of lymph nodes of intravenous drug abusers affected by PGL. Microscopic changes are homogeneous and essentially comparable allowing to subgroup nodes according to their histologic pattern: those with hyperplastic and those with regressive changes. Hyperplastic changes include hyperplasia of germinal centers without or with fragmentation and vascularization, and increased postcapillary venules in the paracortex. Regressive changes are characterized by follicular involution and by follicular depletion with or without fibrosis. Immunohistologic phenotyping shows a peculiar infiltration of CD3/CD8+ lymphocytes in germinal centers and a progressive lysis of follicular dendritic reticulum cells. The presence of HIV antigens can be demonstrated in germinal centers with a reticular pattern paralleling that of follicular dendritic reticulum cells, in endothelial cells of paracortical venules, and in sinus macrophages. Furthermore, HIV genome is sometimes detectable by in situ hybridization in a few endothelial and mononuclear cells of the paracortex. Epstein Barr virus (EBV) antigens are occasionally observed in a few lymph node cells, while EBV genome seems to be absent during the PGL phase of the HIV infection. In conclusion, during PGL, immunohistologic features correlate well with the extent of the histologic changes.","PeriodicalId":77597,"journal":{"name":"Progress in AIDS pathology","volume":"2 ","pages":"33-50"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13259632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benign lymphoepithelial lesion and lymphoepithelial cyst of the parotid gland in HIV infection. HIV感染后腮腺良性淋巴上皮病变及淋巴上皮囊肿。

Progress in AIDS pathology Pub Date : 1990-01-01

F B Smith

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The immunohistology of lymph nodes in HIV infection: a review. HIV感染的淋巴结免疫组织学研究进展。

Progress in AIDS pathology Pub Date : 1990-01-01

G S Wood

{"title":"The immunohistology of lymph nodes in HIV infection: a review.","authors":"G S Wood","doi":"","DOIUrl":"","url":null,"abstract":"Most available evidence indicates that lymph node immunohistologic alterations in HIV-infected patients represent a dynamic process characterized by an initial florid follicular hyperplasia that ultimately progresses to a burned-out, lymphocyte depletion end-point. During this process, HIV-infected cells appear to traffic through the lymph node, and the germinal center serves as a reservoir relatively rich in HIV antigens and intact virus. The localization of HIV within the germinal center may provide one stimulus for the florid follicular hyperplasia typical of early HIV-related lymphadenopathy and may play a role in follicle lysis, a process whereby the accessory cell FDC network of follicles undergoes disruption, which may in turn be responsible for the eventual disappearance of B-cell follicles in late-stage disease. Lymph node CD4+ T cells are selectively depleted with an initial preferential loss of the CD4+ subset concerned with B-cell differentiation. The expression of the CD4 antigen by various other cell types including monocytes, macrophages, histiocytic dendritic cells, and FDC provides one explanation as to why these cells are subject to HIV infection. Except perhaps in end-stage disease, alterations among various lymph node cell subsets do not correlate well with those in the peripheral blood. The latter is therefore regarded as a more sensitive parameter of progressive immunologic changes in HIV infection.","PeriodicalId":77597,"journal":{"name":"Progress in AIDS pathology","volume":"2 ","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13259631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The clinicopathologic spectrum of bacillary (epithelioid) angiomatosis. 细菌性(上皮样)血管瘤病的临床病理谱。

Progress in AIDS pathology Pub Date : 1990-01-01

C J Cockerell

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Disseminated strongyloidiasis and other selected unusual infections in patients with the acquired immunodeficiency syndrome. 获得性免疫缺陷综合征患者的播散性圆线虫病和其他选定的不寻常感染。

Progress in AIDS pathology Pub Date : 1990-01-01

V Glezerov, J R Masci

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Acalculous cholecystitis in the acquired immunodeficiency syndrome. 获得性免疫缺陷综合征的无结石性胆囊炎。

Progress in AIDS pathology Pub Date : 1990-01-01

K Hinnant, H Rotterdam

引用次数: 0