Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry最新文献

{"title":"[Inhibitory effect of recombinant human interferon gamma on human osteoblastic osteosarcoma cells (SaOS2)].","authors":"H Katayama,&nbsp;S Hanazawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent studies have suggested that interleukin-1 or tumor necrosis factor-stimulated bone resorption is mediated by osteoclast-activating factor elaborated by osteoblastic cells. Since recombinant interferon gamma inhibits stimulation of bone resorption by these cytokines, we examined here the effects of recombinant human interferon gamma (rhIFN-G) on DNA synthesis and alkaline phosphatase (ALP) activity of a human osteoblastic osteosarcoma cell line, SaOS2, under preconfluent culture conditions. Addition of rhIFN-G to the cells markedly inhibited their DNA synthesis and ALP activity in a dose-dependent fashion. However, the inhibition was not dependent on the culture time. The highest inhibitory effect was observed in 10% serum-containing culture medium. The inhibitory effect on DNA synthesis was not eliminated by addition of indomethacin, a cyclooxygenase inhibitor. Furthermore, combination of rhIFN-G and recombinant human tumor necrosis factor alpha inhibited their DNA synthesis and the ALP activity in synergistic fashion. Therefore, these data suggest that rhIFN-G is a potent inhibitor for human osteoblastic cells.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"411-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13663146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of bilateral impaction of the lower second molars].","authors":"M Nakasato,&nbsp;M Okitsu,&nbsp;Y Hiranuma,&nbsp;M Eba,&nbsp;Y Hashiguchi,&nbsp;Y Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of bilateral impaction of the lower second molars is presented. A 15-year-old boy with an ill feeling at the right lower first molar was referred to us. X-ray examination revealed bilateral impaction of the lower second molars and the presence of bilateral teeth that seemed to be the unerupted third molars distal to the impacted second molars. Furthermore, a radiolucency approximately 3 X 3 mm in size was detected in the mesioapical region of the right lower first molar. These impactions were managed under local anesthesia by extraction of the right lower first molar and fenestration of the right lower second molar. After approximately 4.5 months, the right lower third molar was extracted. It was further followed approximately 1 month later by extraction of the left lower third molar and ipsilateral fenestration of the lower second molar. As a result, the right lower second molar erupted but it was considerably inclined in a mesial direction. The left lower second molar erupted normally almost up to the occlusal plane. In the absence of systemic abnormality, facial trauma, and maldevelopment of the jaw, impaction seemed to have been closely associated with some unknown local factor.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"147-51"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13744197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Plastic operation of alveolar process by visor osteotomy].","authors":"E Sakamoto,&nbsp;T Kameyama,&nbsp;J Shimada,&nbsp;Y Yamazaki,&nbsp;Y Hashiguchi,&nbsp;Y Yamamoto,&nbsp;K Niikura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Extraction of teeth from the lower jaw often results in atrophy of the alveolar process and mandibular body, and sometimes the atrophy progresses so severely as to seriously affect the fitness of the denture, especially the full denture. If the alveolar ridge is markedly resorbed, patients are not satisfied, unless the alveolar process is surgically heightened and the fitness of the denture is regained. Plastic operation of the alveolar process by visor osteotomy and grafting of the iliac bone was performed on a 54-year-old woman who presented at our Department with a complaint of unfitness of the full denture because of marked atrophy of the mandibular alveolar process. As a result of this operation, a functionally well-fitting denture could be fitted to the satisfaction of this patient. This paper describes the outline of the surgical procedure.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"137-46"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13830162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study of hard mineralized tissues effect of calcium-deficient diets with and without cholecalciferol supplementation on the incisor dentine of rats].","authors":"M Hatano,&nbsp;H Takada,&nbsp;H Fuda,&nbsp;Y Watanabe,&nbsp;K Ikeda,&nbsp;H Hasegawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It has been known that both tooth and bone have an apatite structure similar to that of mineral hydroxyapatite. The apatite crystal in living tissues of tooth and bone generally is constructed from submicrocrystals and has many impurities. It seems that chemical and physical aspects of resistance of hard tissues depend on the diet. Consequently, the matrix of organic, free radicals in X-ray irradiated hard tissues were studied by means of electron spin resonance (ESR). The effects of calcium-deficient diets with and without cholecalciferol supplementation on the incisor dentine of rats were examined by the rate of decay of organic, free fadicals in X-ray irradiated incisor dentine of rats. The crystal size of incisor dentine became smaller in case of calcium contained diet.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 2","pages":"197-204"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Statistical analyses of clinical observations made on outpatients visiting the Department of Oral Diagnosis, Meikai University School of Dentistry Hospital, for the past 16 years].","authors":"K Nakano,&nbsp;N Okada,&nbsp;T Masuda,&nbsp;K Osawa,&nbsp;K Nakada,&nbsp;S Tanaka,&nbsp;M Fujikura,&nbsp;S Goto,&nbsp;Y Nakazato,&nbsp;K Komine","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Statistical analyses of clinical observations made on outpatients visiting the Department of Oral Diagnosis, Meikai University School of Dentistry Hospital from June, 1970, to August 1986 were carried out. The total number of new outpatients during this period was 73,708. The results were as follows: 1) The largest number of patients was found in 1978. 2) There was a tendency for the number of new patients to increase in March, June, and August of every year. The smallest number of patients came in December. 3) The greatest number of new patients visiting the hospital was in the 0-9 age category, followed by those in the 20-29 and 30-39 age categories. 4) The greatest chief complaint of patients visiting the hospital was pain, followed by masticatory disturbance and swelling. 5) The number of outpatients coming to the hospital for cosmetic and temporomandibular joint problems has been increasing on a yearly basis over the past 16 years.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"382-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Two cases of Frey's syndrome].","authors":"M Okitsu,&nbsp;H Harada,&nbsp;K Nagayama,&nbsp;A Tamura,&nbsp;T Shimazaki,&nbsp;M Eba,&nbsp;J Shimada,&nbsp;Y Hiranuma,&nbsp;Y Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During the taking of meals, complex symptoms such as perspiration, rubor, and febrile sensation can appear on the skin overlying the temporal area or the parotid gland after the passage of some time after an operation in the parotid area or trauma inflicted to this area. This phenomenon is usually called Frey's syndrome. We recently encountered two cases of this syndrome. The patients were a 16-year-old boy who developed this syndrome following open reduction of the fractured left temporomandibular articular process and a 72-year-old man who developed it following left hemimandibulectomy and left radical neck dissection performed for the treatment of left mandibular gingival cancer. Frey's syndrome is a relatively rare surgery-associated complication. However, it may be advisable to inform the patient of this possibility prior to an operation, because patients may be severely afflicted by heavy perspiration if this syndrome develops over an extensive area.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"438-44"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Case of multiple macroaneurysms of the retinal arteries].","authors":"T Tashiro,&nbsp;H Masuda,&nbsp;T Ichioka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 74-year-old female with acquired macroaneurysms of the retinal arteries of the left eye is presented. During a follow-up period of three years of this rare case, six macroaneurysms developed one after another. Three of them were treated by argon laser photocoagulation because of severe complications such as retinal haemorrhage and exudation onto the macula. However, recovery of visual function of the final stage following treatment was unsatisfactory. Concerning the unusual clinical course of this case, we speculate that severe arteriolosclerosis of the retinal vessels played a fundamental role in this pathological condition.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"445-53"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13633389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Properties of sialidases from salivary glands, brain, liver and kidney of the rat].","authors":"A Sato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sialidase (SD, neuraminidase, EC 3.2.1 18) is an enzyme which releases terminal sialic acid residues from glycoproteins, glycolipids nad oligosaccharides. In this study, we report some characteristics of this enzyme in rat salivary glands, brain, liver and kidney. SD activity was measured fluorometrically by using the synthetic substrate 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid (4MU-AcNeu). 1. SD activity in tissue homogenates was maximal at pH 4.0 in the submandibular gland (SMG), and at pH 4.5 in both the sublingual gland (SLG) and parotid gland (PG), the values being very similar to those for the activity in brain, liver and kidney. Enzyme activity was highest in SMG, followed by PG and SLG. However, SD activity was lower in these glands than in brain, liver and kidney. 2. Cell fractionation showed that the intracellular distribution of SD in the salivary glands was mainly in the lysosomal fraction, similar to its distribution in brain, liver or kidney. 3. The pH optimum of lysosomal SD was 4.0 in the SMG, and 4.5 in both SLG and PG. The Km value for 4MU-AcNeu of lysosomal SD from all salivary glands was about 0.09 mM. On the other hand, soluble SD in SMG and PG extracts had its pH optimum at 5.5, and a Km value of 0.25mM for 4MU-AcNeu. 4. Studies on heat stability showed SD in the salivary glands and other organs to be very labile, with soluble SD being more labile than lysosomal SD. 5. Lysosomal SD in the PG, brain and liver was inclined to be activated by Ca2+ at low concentrations. Such an effect of Ca2+ was also seen with soluble SD in the SMG, PG and liver. In addition, soluble SD in the SMG was slightly activated by low concentrations of Mg2+. Both Cu2+ and Hg2+ caused a marked inhibition of lysosomal and soluble SD in all organs. 6. By means of Sephacryl S-400 gel filtration, the molecular weight (MW) of lysosomal SD was estimated to be 520,000 in both SMG and SLG, and 460,000 daltons in the PG. The MW of the enzyme in brain, liver and kidney ranged from 350,000 to 460,000. On the other hand, the MW's of soluble SD in SMG and PG were estimated to be 68,000 and 46,000, respectively, by Sephadex G-200 gel filtration. The MW's of soluble SD in brain and liver were very similar to the MW of the corresponding enzyme in the PG.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"307-36"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of various factors involved in bone metabolism on 45Ca2+ incorporation and alkaline phosphatase activity of ROS 17/2.8 cells].","authors":"A Kodama,&nbsp;Y Shioda,&nbsp;K Sugita,&nbsp;K Kurihara,&nbsp;K Hosoi,&nbsp;T Ueha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of interleukin 1, transforming growth factor-beta (coupling factors), prostaglandin E1, and prostaglandin E2 on incorporation of 45Ca2+ and on alkaline phosphatase activity were studied using cultured ROS 17/2.8 cells, one of cell lines derived from rat osteosarcoma. We found that all these factors stimulate both the incorporation of 45Ca2+ and alkaline phosphatase activity of these cells. On the other hand, one of the bone resorption hormones, parathyroid hormone (PTH), suppressed the proliferation of cells and decreased the alkaline phosphatase activity at considerably low concentrations (1 X 10(-12)-1 X 10(-11) M). However, the hormone stimulated the incorporation of 45Ca2+ by these cells in a dose-dependent manner; the maximum stimulation on day 3 was observed at 1 X 10(-7) M and it was approximately 3 times the control value. The data suggest therefore, that the osteoblasts incorporated calcium ions and transported them while bone resorption was occurring. Thus the ROS 17/2.8 cell line appears to be an advantageous experimental system for the study of calcium metabolism of osteoblasts in vitro.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"82-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13744935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Granularity of dental X-ray film. Fundamental study of Wiener spectrum measurement.","authors":"H Yamada,&nbsp;Y Okumura,&nbsp;N Takahashi,&nbsp;S Hokari,&nbsp;Y Kanai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We developed a 16k dots x 100 lines Wiener spectrum measurement system using a microscope-television camera combination. Heretofore, the granularity of film was evaluated from Wiener spectrum using Wiener spectral value in the spatial-frequency independent region obtained by microphotometer as the input device, but this factor is determined by the measurement system and the film emulsion density and there were problems in the evaluation of granularity. Therefore we established a new method for evaluating the granularity from Wiener spectral values in the spatial-frequency independent region through a Wiener spectrum measurement system that utilized a microscope-television camera setup as the input device.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 2","pages":"234-43"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}