J Abe, M Yoshikawa, M Nakamura, H Kiyomura, T Nakamura
{"title":"[Effect of high protein low calcium diet on rat alveolus. 7-day diet].","authors":"J Abe, M Yoshikawa, M Nakamura, H Kiyomura, T Nakamura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes in the bone tissue and the blood vessels in the rat alveolus induced by feeding with a high protein low calcium diet for 7 days were observed by means of light microscopy and scanning electron microscopy. Almost no difference was observed between the control group and the experimental group in the rat femur. However, in the alveolar bone resorption was observed with the appearance of osteoclasts and the enlargement of osteocyte lacunae. The blood vessels in bone marrow spaces showed alternation of their form from straight to slightly ortuous, diverged more frequently and, as a whole, formed a large loop. The vessels ran up and down adjacent to the side wall of the alveolar bone. In the interalveolar septum, ladder-shaped trabeculae and vessels running along them were observed. The present study clearly shows that a high protein low calcium diet affects the alveolar bone in rats, even when given for a short period of 7 days.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 2","pages":"267-75"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Takata, K Katsu, K Sasaki, M Saka, M Hatano, H Hayami, M Sugiura, S Maruyama, A Gemba
{"title":"[Studies on the new clinical marker of diabetes mellitus (5). Seasonal variation of insulin specific binding to erythrocyte insulin receptor].","authors":"H Takata, K Katsu, K Sasaki, M Saka, M Hatano, H Hayami, M Sugiura, S Maruyama, A Gemba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Specific binding of insulin to receptors of healthy human erythrocytes was slightly increased in December (6.9 +/- 1.7%) compared with that in May (5.1 +/- 1.4%). Random screening of insulin specific binding to erythrocyte insulin receptors of various patients (including not only diabetes mellitus but also other diseases) suggested that insulin specific binding is slightly higher in winter than in summer. Insulin specific bindings of healthy subjects in Sapporo (January, -6.1 degrees C), Saitama (5.1 degrees C) and Okinawa (16.0 degrees C) were 9.1 +/- 1.6%, 6.9 +/- 1.7%, 6.2 +/- 1.7%, respectively. A week negative correlation was observed between atmospheric temperature and insulin specific binding. These results suggest that insulin specific binding to the erythrocyte insulin receptor is affected by not only the pathological situation of the patient, but also season and atmospheric temperature.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 3","pages":"291-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13636364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effects of cyproterone acetate on mouse submandibular gland].","authors":"M Ichikawa, S Maruyama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is recognized that the submandibular gland (SMG) of mice is one of the target organs for androgen, and a specific androgen-binding protein (androgen receptor) has been found in the cytosol fraction of this gland. Androgen participates in the production of histochemically and biochemically detected components of this gland through this receptor. Cyproterone acetate (CPA) is a synthetic progestogen which possesses antiandrogenic properties with some synandrogenic action. However, the action of CPA on the SMG has not been well defined. In the present study, the effects of CPA on the granular duct (GD) of the mouse SMG, which is the site of androgen action, were investigated using histometric, histochemical, and biochemical techniques. For histometric and histochemical experiments, normal adult male mice were treated with CPA (20, 40 and 80 mg/kg, S.C.) every second day for 5-30 days. In other experiments, castrated (CAS) and castrated-adrenalectomized (CA) mice were prepared, and they were given an injection of testosterone propionate (TP; 20 mg/kg, S.C.) and/or CPA (20 and 200 mg/kg, S.C.) every second day for 10 days. After the final administration, SMG weights were determined and the size of the GD in the SMG was measured by light microscopy using a micrometer. The sections of SMG were stained with methylgreen-pyronin, bromophenol blue, and p-dimethylaminobenzaldehyde in order to detect RNA (RNA staining), total protein (BPB staining), and granules (Try staining) in the GD, respectively. The intensity of each staining was measured by the method of Sato et al. For biochemical experiments, the mice with testicular feminization (Tfm), which are genetically deficient in androgen receptor, and genetically normal male (X/Y)-castrated mice were used. Both Tfm and X/Y-castrated mice were injected with CPA for histological experiments. After the administration period, the SMG's of both Tfm and X/Y-castrated mice were isolated and esteroprotease activity was determined by the method of Trautschold. The SMG of non-administered X/Y-castrated mice was homogenized in Tris-HCl buffer. And cytoplasmic extracts of SMG's from non-administered X/Y-castrated mice were prepared for detection of inhibitory effect of CPA on specific binding pattern of 3H-methyltrienolone (R1881) by the sucrose density gradient method.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"109-30"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13677320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Shimazaki, T Konuma, M Okitsu, J Shimada, Y Hiranuma, E Sakamoto, Y Yamamoto, H Sumida
{"title":"[Measurement of oral and facial blood flow with a Laser Doppler Flowmeter].","authors":"T Shimazaki, T Konuma, M Okitsu, J Shimada, Y Hiranuma, E Sakamoto, Y Yamamoto, H Sumida","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"411-7"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14209687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Structural mechanics of partial dentures for maxilla bearing an isolated residual tooth - strain distribution].","authors":"H Miyake","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"450-66"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14209688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Determination of epidermal growth factor (EGF) levels in mouse tissues by enzyme immunoassay].","authors":"N Minami, M Kashimata, M Hiramatsu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14282507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Takeshima, E Sakamoto, J Shimada, Y Hiranuma, T Kameyama, A Kougo, K Katoh, Y Yamamoto, H Sumida
{"title":"[Mechanical study on the stability of the titanium mini plate in monocortical osteosynthesis].","authors":"H Takeshima, E Sakamoto, J Shimada, Y Hiranuma, T Kameyama, A Kougo, K Katoh, Y Yamamoto, H Sumida","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"489-94"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14399582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Tetrahydrobiopterin level and NADH-specific dihydropteridine reductase activity in chick embryo liver during development].","authors":"K Matsumoto, N Nakanishi, S Yamada","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"345-52"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14402367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Nishimura, R F Liang, A Kawabata, T Arai, H Mizuno, T Sakata, S Maruyama, M Tajima, S Sato
{"title":"[Effects of aspirin DL-lysine on bone wound healing and bone growth in rats].","authors":"S Nishimura, R F Liang, A Kawabata, T Arai, H Mizuno, T Sakata, S Maruyama, M Tajima, S Sato","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"376-84"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14402371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effects of miscellaneous steroid hormones on dexamethasone inhibition of bone growth and of bone wound healing].","authors":"T Kim, S Nishimura, R F Liang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"17 3","pages":"385-410"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14402372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}