Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry最新文献

{"title":"[Clinical study for prediction of postoperative visual acuity in cataract patients].","authors":"T Tashiro,&nbsp;H Masuda,&nbsp;T Ichioka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to predict more quantitatively postoperative visual acuity in cataract patients, we employed the potential acuity meter (PAM). The PAM projects a Snellen visual acuity chart into the eye by a minute aerial aperture approximately 0.1 mm in diameter. The value of determining potential visual acuity is evident because of the frequent co-existence of macular abnormalities in cataract patients. The 20 cataract patients had an average of 64.8 years (range, 48 to 84 years), and 8 were men and 12 were women. In 23 of the 25 eyes examined, postoperative visual acuity was within two lines or better than the predicted visual acuity with the PAM. Provided the operator is skillful, and if one recognizes its limitations and indications, the PAM is a useful means of predicting postoperative visual acuity in patients with mild or moderate cataracts.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 1","pages":"117-21"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Stimulatory effects of Bacteroides gingivalis fimbriae on production of fibroblasts-derived thymocyte-activating factor (FTAF) by human gingival fibroblasts].","authors":"K Hirose","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bacteroides gingivalis (B. gingivalis) is isolated frequently from subgingival plaques of adult periodontal patients. B. gingivalis is a gram-negative anaerobic organism which has fimbriae on its cell surface. In the present study, B. gingivalis fimbriae were examined for their ability to adhere to human gingival fibroblasts (Gin-1), and to stimulate fibroblast-derived thymocyte-activating factor (FTAF) production by Gin-1 cells. The ability of the fimbriae to bind specifically to Gin-1 cells was clearly shown by competition assay between 125I-labeled and unlabeled fimbriae. Significant stimulatory effect of the fimbriae on FTAF production was observed, when the fimbriae were added to Gin-1 cells at a dose of 1 microgram/ml, and this stimulation was observed as early as 24 hr after addition of fimbriae to the cells. It was verified by a spleen cell mitogenic assay for the fimbriae that the stimulatory effect was not due to lipopolysaccharide (LPS) contamination of the fimbriae preparation. The FTAF activity was inhibited about 50% by recombinant human interleukin-1 (IL-1) beta antiserum but not by recombinant human IL-1 alpha antiserum. Therefore, the present study suggests that B. gingivalis fimbriae may play a functional role in the pathogenesis of adult periodontal disease induced by the microorganism.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 1","pages":"127-36"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13142754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Strength of teeth to fracture by impact. Testing of fractural strength against impact force, using replication models of human permanent teeth].","authors":"H Hosoi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Traumatic injury anterior teeth is often encountered clinically. A number of clinical and statistical studies have so far been undertaken for the incidences, causes and ages in terms of the site of fracture. However, little has been attempted at fundamental estimation of the fractural resistance of anterior teeth that are susceptible to fracture. This has been studied in only an erect position of eruption by Nose or Chin. Changes in resistance of teeth in a twisted position or at different angles of eruption still remain unstudied. We took an interest in the relation between physicopositional conditions of human teeth and changes in their fractural strength against impact. Determination of the resistance of teeth to a variety of experimental conditions was attempted by use of an Izod-type tester. Epoxy resin replication models of human anterior teeth were used as experimental specimens, since human teeth were considered inappropriate because of their large individual differences and an anticipated difficulty in precise reproduction of the angles of eruption and torsion. The following results were obtained; (1) In the replication models of teeth erected positioned at 90 degrees vertically to the horizontal plane, the fractural strength against impact was highest for the maxillary cuspid model and was lowest for the mandibular central incisor model. (2) In the replication models of teeth with their mesial or distal incisal margin twisted 45 degrees medially, the fractural strength was reduced for all the teeth except the maxillary central incisors. (3) In comparison of the strength between the replication models with the mesial incisal margin twisted 45 degrees medially and those with the distal incisal margin twisted likewise am marked reduction in strength was found for the maxillary cuspid model prepared in the former condition of torsion. For the mandibular cuspid model, a relatively large reduction of the strength was found in the latter condition of torsion. (4) In comparison of the strength of teeth positioned at various angles, the strength was decreased by slanting either labially or lingually for all the replication models except the maxillary and mandibular cuspid models.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 2","pages":"251-66"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Inducing effect of tumor necrosis factor-alpha on differentiation of U937 monocytic tumor cell line].","authors":"H Hashimoto,&nbsp;S Hanazawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We used the human monocyte/macrophage-like tumor cell line U937 to examine whether tumor necrosis factor-alpha (TNF-alpha) induces differentiation of monocyte/macrophage progenitors. Incubation of these cells with recombinant human tumor necrosis factor-alpha (rhTNF-alpha) resulted in an increase in Fc rosette formation by the cells. RhTNF-alpha increased the rosette formation in dose- and culture time-dependent manners. And the highest Fc rosette formation was observed in culture medium supplemented with 10% serum. However, U937 cell growth was not inhibited by rhTNF-alpha. The stimulatory effect of rhTNF-alpha was completely inhibited when the factor and indomethacin (10(-6) M) were added simultaneously to the cells. Also, rhTNF-alpha increased NBT reducing activity of the cells. Additionally, rhTNF-alpha-treated U937 cells produced interleukin-1 in the cell density- and culture time-dependent fashions. These results demonstrate that rhTNF-alpha is a potent inducer of the differentiation of the monocyte/macrophage-like tumor cell line U937.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 2","pages":"267-76"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of 2,5-hexanedione and N-methylformamide in urine by gas chromatography.","authors":"M Sugiura,&nbsp;Y Kosaka,&nbsp;Y Kawano,&nbsp;S Maruyama,&nbsp;T Gemba,&nbsp;K Katsu,&nbsp;M Hatano,&nbsp;M Ishihara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Methods for the clinical testing of 2,5-hexanedione and N-methylformamide, urinary metabolites of n-hexane and N,N-dimethylformamide, respectively, were established by capillary column GLC. Recovery rates of 2,5-hexanedione and N-methylformamide from urine were 80.2-108.9% and 99.6-104.2%, respectively. Coefficients of variation (C.V.) for the amount of each product added were 3.1%, 1.8% (intra-assay) and 5.7%, 3.3% (inter-assay), respectively. The concentration ranges of metabolites from urine of healthy subjects without exposure to these organic solvents were less than or equal to 0.5 mg/l (2,5-hexanedione), less than or equal to 1.5 mg/l (N-methylformamide), respectively.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 1","pages":"63-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparative anatomical study on the ductal systems of rabbit and cat parotid glands].","authors":"J Okugawa,&nbsp;H Fujii","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A comparative study on the ductal systems of rabbit and cat parotid glands was performed by scanning and transmission electron-microscopies, and by light microscopy. Stereological structures of both ductal systems, which were observed as resin casts, resembled one another closely. Each branch showed repeated tree-like ramifications and the striated duct and the intercalated duct took a short linear course. The development of these ducts was poor. Numerous micromorphological differences and resemblances between rabbit and cat were found: Acinus 1. Rabbits had serous acini; and cats, seromucous ones. 2. In both specimens, secretory material was present in the intercellular spaces and these spaces were enlarged. 3. Secretory granules surrounded by a limiting membrane were present in the terminal lumen in cats, but not in rabbits. Intercalated duct 4. Small secretory granules occupying the supranuclear portion were present in rabbits and cats except the proximal region of the striated duct in rabbits. 5. Spherical secretory granules were present in the lumen in cats, but not in rabbits. Striated duct 6. The walls of the duct in both animals were composed of three types of cells; the light cell, the dark cell, and the basal cell. 7. Small secretory granules occupied the apical portion of the light cell in cats. 8. Spherical secretory granules were observed in the lumen in cats, but not in rabbits.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 1","pages":"21-42"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of estimation of color recognition on the dentist. On the ability of subjects to discriminate color in terms of hue, value and chroma.","authors":"S Kijima,&nbsp;H Henzan,&nbsp;Z Y Niu,&nbsp;K Nakaura,&nbsp;T Kohchi,&nbsp;S Ishihara,&nbsp;T Katayama,&nbsp;T Enya,&nbsp;I Katayama,&nbsp;T Motonomi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The tooth crown color space model was manufactured and the improvement of the color representation and communication on the dental clinic have been trying. The study of color discrimination by dentist and student viewing with the use of tooth crown color chips reported here in basic knowledge on the color sensitivity of human eye. The test card were 55 x 90 mm in size and the color chip, 5 x 10 mm. The paired color chips were placed on the test card to have a 2 mm distance between them. Color difference of two tooth crown color chips on the test cards was 3.5 (delta E*ab), the combination of hue, value and chroma was constant of all cards. The subjects were 22 people, 6 dentists and 16 dental school students with normal color sensibility. In proportion of method of comparison for surface color (JIS Z 8723), the subject observed the test card which were different of hue, value and chroma on the their naked-eye, were investigated to evaluate their judgement of the test cards. The following results were obtained. The standard of judgment for the color discrimination was made firstly in terms of hue, secondly in terms of value, and thirdly in terms of chroma.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 3","pages":"377-82"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of transforming growth factor-beta 1 on murine clonal osteoblastic cells (MC3T3-E1).","authors":"M Okawa,&nbsp;Y Hakeda,&nbsp;N Wakatsuki,&nbsp;Y Katoh,&nbsp;K Higashino,&nbsp;M Kumegawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Transforming growth factor (TGF)-beta family is considered to be an important local factor that greatly regulates bone metabolism. However, the effects of this polypeptide on osteoblasts have been divergent under various experimental conditions. Moreover, three forms of TGF-beta have been recently described. Therefore, we reexamined the effects of TGF-beta 1 on clonal murine osteoblastic MC3T3-E1 cells. TGF-beta 1 dose- and time-dependently depressed alkaline phosphatase activity in the cells supported by low concentration of serum. On the contrary, in the same range of concentrations, TGF-beta 1 stimulated DNA synthesis in the cells. These effects of TGF-beta 1 were observed in the cells cultured in the media without or with a high concentration of serum. These effects of TGF-beta 1 are not mediated by endogenous production of prostaglandin, since the basal level of prostaglandin E2 was very low and rather inhibited by TGF-beta 1; and, further, indomethacin did not modify the effects of TGF-beta 1 on the cells under the present conditions. Furthermore, TGF-beta 1 greatly stimulated not only type I but also type III collagen production. Hydroxyurea completely blocked the stimulation of DNA synthesis by TGF-beta 1, but partially inhibited the collagen synthesis, suggesting that the TGF-beta 1-stimulated collagen synthesis is at least in part linked to the proliferation. However, the stimulation of collagen synthesis by TGF-beta 1 was greater than that of DNA synthesis, and further, the amount of hydroxyproline in the cell was evidently augmented by TGF-beta 1. Our data presented here thus suggest that TGF-beta 1 may act on preosteoblasts to increase the number of osteoblasts and the amount of bone organic matrix.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"19 3","pages":"310-22"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13289753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Electron microscopic observation of the soft tissue in the gubernacular canal. 3. Changes in the components with aging].","authors":"K Ogi,&nbsp;H Goto,&nbsp;H Nakahara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present study, we observed the epithelial remnants in the gubernacular canal of a 3-month-old crab-eating monkey by transmission electron microscopy, and compared our findings with those in a 1-year-old one. The following results were obtained: 1. The basal lamina of the epithelial remnants of the 3-month-old monkey was more clearly seen than that of the older animal, and it had a brush-like appearance probably due to relatively high forming activity. 2. No marked difference was observed among the cellular components between the two ages. The tonofilaments which were fibrous in ordinary epithelial cells already showed some aggregation and granular appearance in the 3-month material. 3. In most parts of the 3-month-old material, only a small number of atrophied cells were observed; however in the epithelial remnants located near the gingival epithelium, we observed cells containing swollen mitochondria which probably occurred due to the degeneration of the cells. 4. The density of collagen fibers around the dental germ was relatively low, whereas in the area close to the gingiva, the density of fibers was very high. 5. In the present study, no components exactly derived from the remnants of epithelial cells were observed within the extracellular spaces of the connective tissue.</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"53-62"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13744932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effect of inorganic anions on the activity of dental pulp lactate dehydrogenase].","authors":"M Sano,&nbsp;N Sato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pig dental pulp lactate dehydrogenase (EC. 1.1.1.27; LDH) isozymes were separated by DEAE Sephadex A-50 column chromatography, and LDH-1 isozyme was purified by blue dextran affinity chromatography. The specific activity of pig dental pulp LDH-1 was 193.2 units/mg protein, and the purified enzyme showed a single protein band on disk electrophoresis. In this paper, we studied the effect of inorganic ions on the activity of pig dental pulp LDH-1 isozyme, and compared it with that of affected by anions. Dental pulp and heart muscle LDH-1 isozymes were inhibited at a low pyruvate concentration; otherwise, at a high pyruvate concentration, each enzyme activity was enhanced by the anions. But the effect of SO2(2-) was different from that of the other anions: SO2(2-) did not activate the enzyme at a high pyruvate concentration. In the dental pulp, the Km values for pyruvate were 1 order of magnitude smaller by SO2(2-), and 1 order higher by other anions than the control value. In the heart muscle, the Km values were not changed by anions, except by SO2(2-).</p>","PeriodicalId":77571,"journal":{"name":"Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry","volume":"18 1","pages":"63-73"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13744933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}