Anaesthesia最新文献

{"title":"Efficacy of laparoscopic-installed rectus sheath block for postoperative pain reduction in transabdominal preperitoneal inguinal hernia repair: a double-blind, randomised-controlled trial.","authors":"Manuel Altenburg,Timo Rath,Atingwa Tasi,Oliver Mann,Salman Yousuf Guraya,Thorsten Krause,Tim Strate,Jonas Herzberg","doi":"10.1111/anae.16680","DOIUrl":"https://doi.org/10.1111/anae.16680","url":null,"abstract":"INTRODUCTIONPostoperative pain management plays a crucial role in early recovery after laparoscopic inguinal hernia repair, particularly as most repairs are done as day-case surgery. The aim of this study was to evaluate the anaesthetic effect of a laparoscopically-guided rectus sheath block on postoperative pain.METHODSWithin this prospective, double-blinded, randomised controlled trial, patients planned for inguinal hernia repair using the transabdominal preperitoneal patch plastic were recruited. Patients were assigned randomly to either a control group or an intervention group. Both received standardised pre-emptive anaesthesia during the surgical procedure with self-fixating mesh. In the intervention group, an intra-operatively implemented rectus sheath block was performed for postoperative pain control. The primary outcome was the postoperative pain score 3 h after surgery.RESULTSThirty-five patients were included in the study; 17 patients were randomised to the intervention group and 18 to the control group. Patient demographics and procedural times were similar in both groups. Postoperative median (IQR [range]) pain scores were not significantly different between the groups 3 h after surgery (intervention group 3.0 (3.0-5.0 [1.0-8.0]) vs. control group 3.5 (2.25-4.75 [1.0-8.0]); p = 0.854). The median (IQR [range]) oxycodone requirement after surgery was not different between the groups (intervention group 0 (0-3 [0-7]) mg vs. control group 0 (0-3 [0-7]) mg; p = 0.869).DISCUSSIONThis study has shown that a laparoscopic rectus sheath block has no beneficial effect in postoperative pain management following laparoscopic transabdominal inguinal hernia repair.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"23 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144622172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Information – Editorial Board","authors":"","doi":"10.1111/anae.16342","DOIUrl":"https://doi.org/10.1111/anae.16342","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 8","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.16342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dose‐dependent relationship between intra‐operative ketamine administration and postoperative delirium: a retrospective cohort study","authors":"Lars Kaiser, Béla‐Simon Paschold, Luca J. Wachtendorf, Elena Ahrens, Theresa Tenge, Simone Redaelli, Max Hentges, Sebastian D. Sahli, Guanqing Chen, Victor Novack, Matthias Eikermann, Haobo Ma, Maximilian S. Schaefer","doi":"10.1111/anae.16681","DOIUrl":"https://doi.org/10.1111/anae.16681","url":null,"abstract":"SummaryIntroductionKetamine is used frequently as an adjunct for general anaesthesia, exerting analgesic and opioid‐sparing properties at lower doses and psychotomimetic effects at higher doses. All dose ranges may have effects on the incidence of postoperative delirium, but clinical trials have been equivocal. We hypothesised that intra‐operative low‐dose ketamine is associated with a lower risk of postoperative delirium.MethodsA total of 106,982 adult patients undergoing general anaesthesia for non‐cardiac, non‐neurosurgical and non‐transplant procedures between 2008 and 2024 were included. Primary exposure was the intra‐operative cumulative ketamine dose (mg.kg<jats:sup>‐1</jats:sup> body weight) dichotomised into high vs. low‐dose, based on the median of the cohort. Primary outcome was postoperative delirium within 7 days, based on keyword‐based search strategy, manual chart review, Confusion Assessment Method recordings and International Classification of Diseases diagnostic codes. Multivariable logistic regression and fractional polynomial regression analyses to assess a potential nonlinear dose–response relationship were performed.ResultsPostoperative delirium occurred in 2837 (2.7%) patients. In total, 12,199 (11.4%) patients received ketamine, with a median (IQR [range]) intra‐operative dose of 0.35 (0.25–0.52 [0.01–3.86]) mg.kg<jats:sup>‐1</jats:sup>. Compared with patients not receiving ketamine, a low dose (≤ 0.35 mg.kg<jats:sup>‐1</jats:sup>, 6109 patients) was associated with lower risks of postoperative delirium (adjusted odds ratio 0.74 (95%CI 0.59–0.89), adjusted risk difference ‐0.7% (95%CI ‐1.0 to ‐0.3%); p = 0.003). Higher doses of ketamine (&gt; 0.35 mg.kg<jats:sup>‐1</jats:sup>, 6090 patients) did not affect the risk of postoperative delirium (adjusted odds ratio 1.00 (95%CI 0.85–1.18); p = 0.96). Fractional polynomial regression analyses indicated a U‐shaped dose–response relationship, with a minimum postoperative delirium risk at a cumulative ketamine dose of 0.25–0.34 mg.kg<jats:sup>‐1</jats:sup>.DiscussionIntra‐operative low‐dose ketamine was associated with a lower risk of postoperative delirium, while high doses did not influence the risk.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"4 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimising same‐day discharge: the impact of opioid and anti‐emetic prescribing in day surgery","authors":"Sophie Horrocks, Anna Dickson, Amanda Bull, Nora Villamil, Ian J. B. Young","doi":"10.1111/anae.16685","DOIUrl":"https://doi.org/10.1111/anae.16685","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"21 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Creating communities of practice in emerging health economies","authors":"Walter Eppich, Stuart D. Marshall","doi":"10.1111/anae.16683","DOIUrl":"https://doi.org/10.1111/anae.16683","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"3 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does optimisation of heart failure equate to fitness for surgery?","authors":"Sebastian Vaughan-Burleigh,&nbsp;Nikant Sabharwal,&nbsp;James R. Day","doi":"10.1111/anae.16682","DOIUrl":"10.1111/anae.16682","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"80 8","pages":"899-903"},"PeriodicalIF":7.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial commitment to trust and integrity in science: implications for pain and anaesthesiology research*","authors":"Tonya M. Palermo, Didier Bouhassira, Karen D. Davis, Hugh C. Hemmings, Robert W. Hurley, Joel Katz, Jaideep J. Pandit, Theodore J. Price, Michael E. Schatman, Stephan K. W. Schwarz, Dennis C. Turk, Marc Van de Velde, Matthew D. Wiles, Tony L. Yaksh, David Yarnitsky","doi":"10.1111/anae.16655","DOIUrl":"https://doi.org/10.1111/anae.16655","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"27 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of invasive arterial blood pressure monitoring in routine anaesthesia practice: an analysis from the NAP7 project","authors":"Andrew D. Kane, Jasmeet Soar, Richard A. Armstrong, Iain K. Moppett, Emira Kursumovic, Tim M. Cook","doi":"10.1111/anae.16679","DOIUrl":"https://doi.org/10.1111/anae.16679","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"47 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144520349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification of difficult videolaryngoscopic tracheal intubation with different blade types: a prospective external validation study of the VIDIAC score.","authors":"Vera Köhl,Viktor A Wünsch,Thorsten Dohrmann,Linda Krause,Martin Petzoldt","doi":"10.1111/anae.16678","DOIUrl":"https://doi.org/10.1111/anae.16678","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"36 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the discussion on airway management with glucagon‐like peptide‐1 receptor agonist use","authors":"Jenny E. Pennycuff, Katherine Hagan, Juan Cata","doi":"10.1111/anae.16676","DOIUrl":"https://doi.org/10.1111/anae.16676","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"36 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}