AnaesthesiaPub Date : 2025-09-28DOI: 10.1111/anae.70004
Maximilian S Schaefer,
{"title":"Does low-dose ketamine really protect against delirium? A reply.","authors":"Maximilian S Schaefer, ","doi":"10.1111/anae.70004","DOIUrl":"https://doi.org/10.1111/anae.70004","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"66 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-28DOI: 10.1111/anae.70020
{"title":"Correction to: Association of Anaesthetists guidelines: the use of blood components and their alternatives.","authors":"","doi":"10.1111/anae.70020","DOIUrl":"https://doi.org/10.1111/anae.70020","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"37 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-28DOI: 10.1111/anae.70007
Keta Thakkar
{"title":"Patient education as the bridge to meaningful consent in anaesthesia.","authors":"Keta Thakkar","doi":"10.1111/anae.70007","DOIUrl":"https://doi.org/10.1111/anae.70007","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"1 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-28DOI: 10.1111/anae.70005
Yi Zhang,Linyun Wang,Xiaofeng Lei
{"title":"Remimazolam for intravenous anaesthesia in children: reassessing the dose-onset relationship.","authors":"Yi Zhang,Linyun Wang,Xiaofeng Lei","doi":"10.1111/anae.70005","DOIUrl":"https://doi.org/10.1111/anae.70005","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"27 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-26DOI: 10.1111/anae.70011
Vivian M Yuen,Michael G Irwin
{"title":"Expanding the role of intranasal dexmedetomidine in peri-operative care.","authors":"Vivian M Yuen,Michael G Irwin","doi":"10.1111/anae.70011","DOIUrl":"https://doi.org/10.1111/anae.70011","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"73 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The combination of interpectoral plane and superficial serratus anterior plane blocks for the prevention of persistent pain after total mastectomy: a triple-blinded, randomised, placebo-controlled trial.","authors":"Hiroyuki Kono,Daisuke Sugiyama,Toru Teraguchi,Kenichi Ueda,Osamu Kobayashi,Eisuke Fukuma,Hiroki Matsui,Hiroshi Morimatsu","doi":"10.1111/anae.16787","DOIUrl":"https://doi.org/10.1111/anae.16787","url":null,"abstract":"INTRODUCTIONChronic post-mastectomy pain may be preventable with regional analgesia. Ultrasound-guided fascial plane blocks are accepted alternatives to paravertebral block for patients undergoing mastectomy. While fascial plane blocks may be used individually, combining them may be more effective. This study tested the hypothesis that combining interpectoral plane and superficial serratus anterior plane blocks would reduce the incidence of chronic post-mastectomy pain compared with the superficial serratus anterior plane block alone.METHODSWe enrolled adult women scheduled to undergo total mastectomy with or without lymph node dissection. The intervention group received both interpectoral plane and superficial serratus anterior plane blocks with 0.375% ropivacaine pre-operatively. The control group received saline as the interpectoral plane injection and a superficial serratus anterior plane block with 0.375% ropivacaine. The primary outcome was the incidence of any pain at rest at 6 months postoperatively. Secondary outcomes included pain intensity and location at rest and with movement at 2 h, 24 h, 1 month, 3 months and 6 months postoperatively.RESULTSIn total, 100 patients were enrolled and allocated randomly. For the primary outcome by intention-to-treat analysis, nine (18%) patients allocated to the intervention group reported post-mastectomy pain at rest at 6 months postoperatively compared with 19 (38%) allocated to the control group (OR 0.36, 95%CI 0.13-0.98, p = 0.044). Per-protocol analysis, not including three cases of protocol violation, showed no difference between groups for the same comparison. Pain scores were very low in both groups at 6 months postoperatively, and no patient was still using analgesics. There were no differences in acute pain scores or other secondary outcomes.DISCUSSIONThe addition of interpectoral plane block to superficial serratus anterior plane block may reduce the incidence of rest pain at 6 months post-mastectomy. Other factors influence chronic postsurgical pain development and deserve further study.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"38 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-25DOI: 10.1111/anae.70010
Jasmine Tattsbridge,Andre Vercueil
{"title":"Inguinal hernia repair as a tracer condition: lessons from the Hernia International Project Promoting Outcomes (HIPPO) study.","authors":"Jasmine Tattsbridge,Andre Vercueil","doi":"10.1111/anae.70010","DOIUrl":"https://doi.org/10.1111/anae.70010","url":null,"abstract":"","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"87 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145140414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-24DOI: 10.1111/anae.16752
D. N. Lucas, James H. Bamber, Gary Stocks, Paul Sharpe, Marian Knight
{"title":"Incidence, risk factors, management and outcomes of high neuraxial block in obstetric anaesthetic practice: a prospective national observational study using the UK Obstetric Surveillance System","authors":"D. N. Lucas, James H. Bamber, Gary Stocks, Paul Sharpe, Marian Knight","doi":"10.1111/anae.16752","DOIUrl":"https://doi.org/10.1111/anae.16752","url":null,"abstract":"SummaryIntroductionHigh neuraxial block has been identified as a leading cause of maternal cardiac arrest in the UK. There is a need to investigate the potential risk factors and causes of high neuraxial block in obstetrics to reduce its occurrence.MethodsWe investigated the incidence, risk factors, management and outcomes of high neuraxial block presenting in maternity care in the UK using the UK Obstetric Surveillance System. High neuraxial block was defined as spinal and/or epidural anaesthesia/analgesia that required ventilatory support and/or cardiopulmonary resuscitation.ResultsThere were 89 reports of high neuraxial block reported between 2017 and 2019. The estimated overall incidence was 14.7/100,000 (95%CI 11.8–18.0) neuraxial blocks, with the incidence of high neuraxial block of 19.6/100,000 (95%CI 14.9–25.3) after spinal anaesthesia and 7.0/100,000 (95%CI 4.6–10.1) after epidural analgesia or anaesthesia. The most common anaesthetic intervention that preceded a high neuraxial block was a single‐shot spinal following labour epidural analgesia (43/89 of all cases), of which 37% (16/43) occurred after an unsuccessful epidural top‐up to convert epidural analgesia to anaesthesia. Inadvertent dural puncture occurred in 15/89 cases. There were six cases of cardiac arrest. There were no maternal or neonatal deaths. Seven patients were reported to have been psychologically distressed and/or had awareness during tracheal intubation because of the high neuraxial block and its management.ConclusionWhilst high neuraxial block is rare in UK obstetric practice and generally managed well, directed attention to key aspects of clinical practice may ameliorate the risk. These include strategies to minimise acute supine hypotension with induction of spinal anaesthesia; prudent intrathecal local anaesthetic dosing; and careful case selection for converting epidural analgesia to anaesthesia for caesarean birth.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"16 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AnaesthesiaPub Date : 2025-09-24DOI: 10.1111/anae.70013
Marie José Lahoud, Samuel Tell Gurary, Nadia Elia
{"title":"Hypnosis for anaesthetists: a systematic review and meta‐analyses","authors":"Marie José Lahoud, Samuel Tell Gurary, Nadia Elia","doi":"10.1111/anae.70013","DOIUrl":"https://doi.org/10.1111/anae.70013","url":null,"abstract":"SummaryIntroductionTherapeutic hypnosis appears to offer psychological and physiological benefits in various medical fields, but despite increasing interest, its value for anaesthesia remains inconclusive.MethodsWe searched for studies of any design in which hypnosis was used for any intervention requiring the presence of an anaesthetist, alone or in combination with any type of anaesthesia, on children and adults. Meta‐analyses using random‐effects models were stratified on hypnosis timing, when three or more randomised controlled trials reported on a similar outcome. Additional analyses were performed adding data derived from non‐randomised controlled studies. The primary outcome was the use of hypnotics and opioids during the intervention. Secondary outcomes included all outcomes related to pain, anxiety or adverse events.ResultsWe identified 142 studies that included 9238 patients (8319 adults, 919 children). Pre‐intervention hypnosis decreased post‐intervention visual analogue scale pain score (mean difference ‐0.88 cm, 95%CI ‐1.72 to ‐0.05) and anxiety (standardised mean difference ‐0.76, 95%CI ‐1.14 to ‐0.38). Per‐intervention hypnosis decreased visual analogue scale pain intensity during the intervention (mean difference ‐1.14 cm, 95%CI ‐1.86 to ‐0.41) without impacting on post‐intervention pain; decreased post‐intervention anxiety (standardised mean difference ‐0.44, 95%CI ‐0.75 to ‐0.13); and lowered the risk of postoperative nausea and vomiting (risk ratio 0.43, 95%CI 0.25–0.74). Adding non‐randomised controlled studies did not alter these results substantially. Evidence of the impact of pre‐ or per‐intervention hypnosis on other outcomes, or of post‐intervention hypnosis on any outcome, was lacking.DiscussionHypnosis may help reduce anxiety, alleviate pain during and after a procedure and lower the incidence of postoperative nausea and vomiting. However, despite the inclusion of more than 9000 patients in studies examining the use of hypnosis for anaesthesia, its impact on most outcomes remains unknown.","PeriodicalId":7742,"journal":{"name":"Anaesthesia","volume":"22 1","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}