{"title":"A comparative study of tear secretion in blepharospasm and hemifacial spasm patients treated with botulinum toxin.","authors":"J Price, J O'Day","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the neuro-ophthalmology clinic at St. Vincent's Hospital, Melbourne, 57 patients with blepharospasm and 50 patients with hemifacial spasm were treated with botulinum toxin. Schirmer tear tests were conducted on all the patients prior to each treatment and at 1 week following treatment where possible. The results were compared with a control group of 107 patients selected by age and sex. The blepharospasm patients were found to have a significantly lower tear secretion than that of the control group, using the Mann-Whitney test (median = 3.5 mm, compared with median-11.0 mm, p < .0001). This did not improve following treatment. The patients with hemifacial spasm did not have significantly different tear secretion from that of the control group (t = 1.0, p > .05). To investigate whether there was any relationship between the symptoms and the result of the Schirmer test, a survey was also conducted on the patients with blepharospasm and hemifacial spasm regarding symptoms, frequency, and type of drops/ointment used.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The four-meter confrontation visual field test.","authors":"S R Kodsi, B R Younge","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Confrontation visual fields have limited value in testing paracentral vision. We have used a four-meter confrontation test for several years at the Mayo Clinic for screening of the central field. This test can identify paracentral scotomas and macular sparing in a homonymous hemianopia. The optics of this technique parallel those of the two-meter tangent screen examination in which a scotoma is greatly enlarged by doubling the test distance. Although in common usage by some neuro-ophthalmologists, this simple technique is useful as an office screening device for evaluating paracentral vision.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"40-3"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visual loss as the initial presentation of nasopharyngeal carcinoma.","authors":"L Y Kao, H C Chuang, Y S Liang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eye symptoms and cranial nerve involvement are rather common in nasopharyngeal carcinomas, but early invasion of the optic nerve is very rare. Two cases of nasopharyngeal carcinoma that presented initially with visual loss are reported.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"24-6"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J A Downie, I C Francis, J J Arnold, L M Bott, S Kos
{"title":"Sudden blindness and total ophthalmoplegia in mucormycosis. A clinicopathological correlation.","authors":"J A Downie, I C Francis, J J Arnold, L M Bott, S Kos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of rhino-orbitocerebral mucormycosis is presented, illustrating the serious nature of this disease. Clinical features and their pathological correlations are demonstrated. The need for a high index of clinical suspicion, and an early biopsy of the affected area is emphasized so that the benefits of early diagnosis and therapy may be gained.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T A Moody, A R Irvine, P H Cahn, J O Susac, J C Horton
{"title":"Sudden visual field constriction associated with optic disc drusen.","authors":"T A Moody, A R Irvine, P H Cahn, J O Susac, J C Horton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report two patients with optic disc drusen who suffered sudden, concentric constriction of the visual field. Visual acuity remained normal. The involved discs showed no swelling, hemorrhage, or other evidence of anterior ischemic optic neuropathy. We are unable to explain the mechanism or the pattern of visual field loss in these unusual cases.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"8-13; discussion 14"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unilateral conjugate gaze palsy due to a lesion of the abducens nucleus. Clinical and neuroradiological correlations.","authors":"G Hirose, K Furui, A Yoshioka, K Sakai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a case of left-sided horizontal gaze palsy, ipsilateral adduction weakness, and left peripheral facial weakness, all of which indicate the lesion in the left median pontine tegmentum. The enhanced MRIs revealed a discrete left median pontine tegmental lesion, involving the abducens nucleus, MLF, and facial nerve knee. This lesion spared the area of the left PPRF. Among these structures, the area of the abducens nucleus seems to be responsible for the unilateral horizontal gaze palsy. We are not aware of any previous precise neuroradiological documentation of unilateral paralysis of conjugate gaze due to a lesion of the abducens nucleus by sagittal and horizontal MRIs.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"54-8"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Kumar, S Sandramouli, L Verma, H K Tewari, P K Khosla
{"title":"Ocular ethambutol toxicity: is it reversible?","authors":"A Kumar, S Sandramouli, L Verma, H K Tewari, P K Khosla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Delayed onset ocular ethambutol toxicity is usually considered to be reversible following prompt withdrawal of the drug. However, in a series of seven consecutive patients with severe visual deficit due to ethambutol toxicity, only 42.2% (3 of the 7 patients) achieved a visual recovery of better than 20/200 after an average follow-up of 8.3 +/- 2.1 months after stoppage of the drug. On fluorescein angiography, three cases (42.2%) progressed to optic atrophy during the follow-up with permanent visual damage. There were no predisposing or risk factors to contribute toward the poor visual gain. In this background, we recommend discontinuation of ethambutol from the antituberculous regimen. As an additional sidelight, the value of visually evoked potential in the monitoring of patients on ethambutol, especially in cases with early periaxial neuritis, has been emphasised.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"15-7"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L M Hamed, J Silbiger, J Guy, J P Mickle, P Sibony, A Cossari, M Andriola
{"title":"Parainfectious optic neuritis and encephalomyelitis. A report of two cases with thalamic involvement.","authors":"L M Hamed, J Silbiger, J Guy, J P Mickle, P Sibony, A Cossari, M Andriola","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two children developed mental status alteration and bilateral profound visual loss secondary to optic neuritis. The clinical picture was consistent with parainfectious encephalomyelitis. Magnetic resonance imaging showed bilateral involvement of the thalamus in both cases. In one case the thalamic involvement was solitary and was suspected initially to represent a primary thalamic neoplasm. This was ruled out by a stereotactic biopsy of the thalamus, which showed perivascular inflammation consistent with parainfectious encephalomyelitis. The clinical and neuroimaging findings improved significantly following corticosteroid administration. Several relapses occurred upon initial attempts at corticosteroid cessation.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19092324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transient cortical blindness due to hypertensive encephalopathy. Magnetic resonance imaging correlation.","authors":"T R Marra, M Shah, M A Mikus","doi":"10.3109/01658109309037000","DOIUrl":"https://doi.org/10.3109/01658109309037000","url":null,"abstract":"<p><p>Striking reversible signal intense magnetic resonance imaging (MRI) lesions were observed in the occipital cortex of a 16-year-old girl who presented with an attack of transient cortical blindness as the initial manifestation of hypertensive encephalopathy (HTE). The lesions were seen to best advantage on T2-weighted imaging and were not visible on computed tomography (CT). It is proposed that such occipital lobe MRI lesions likely reflect extravasation of fluid and proteins across the blood brain barrier, damaged as a consequence of cerebral autoregulation failure.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 1","pages":"35-7"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/01658109309037000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19483895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}