{"title":"Trilateral Retinoblastoma","authors":"","doi":"10.32388/dpeidi","DOIUrl":"https://doi.org/10.32388/dpeidi","url":null,"abstract":"INTRODUCTION Trilateral retinoblastoma (TR) is characterised by an intracranial neuroblastic tumour arising in the pineal region, associated with hereditary retinoblastomas which are usually bilateral but may also be unilateral. TR is rare, occurring in 3% of cases and is usually fatal . From August 2001 till December 2009, a total of 141 cases of retinoblastoma were seen at our institution. During this time, two children progressed to trilateral disease (1.4%).","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69629225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recovery of vision in a 47-year-old man with fulminant giant cell arteritis.","authors":"E A Postel, S C Pollock","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Giant cell arteritis is a systemic necrotizing vasculitis that often causes profound and irreversible visual loss in elderly individuals. We describe a 47-year-old man with fulminant giant cell arteritis whose clinical picture included severe visual loss and several unusual or previously unreported findings. Aggressive treatment with intravenous corticosteroids resulted in a dramatic improvement in the patient's vision. Although no firm conclusions can be drawn from the outcome in a single case, we believe that, in some patients with arteritic ischemic optic neuropathy, aggressive treatment with intravenous corticosteroids may be associated with a better visual prognosis than treatment by the oral route.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"262-70"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19105546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J R Piltz, C Wertenbaker, S E Lance, T Slamovits, H F Leeper
{"title":"Digoxin toxicity. Recognizing the varied visual presentations.","authors":"J R Piltz, C Wertenbaker, S E Lance, T Slamovits, H F Leeper","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report three cases of digoxin toxicity presenting with decreased visual acuity, unaccompanied by the classic visual symptom of xanthopsia. Visual function improved and symptoms diminished upon lowering of blood digoxin level. Electroretinographic (ERG) abnormalities in the first case were suggestive of a cone deficit, which supports recent electrodiagnostic and labeled tracer studies implicating retinal dysfunction in the pathogenesis of digoxin toxicity. The second patient presented with visual symptoms exclusively. Evaluation of the third case was hampered by advanced retinitis pigmentosa and the presentation was complicated by a syncopal episode. Digoxin toxicity is a potentially life-threatening condition. Ophthalmologists and neurologists may be the first physicians consulted. It must be considered in the differential diagnosis in patients with otherwise unexplained visual loss.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"275-80"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19106104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"History of the Frank B. Walsh Society.","authors":"D L Knox","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"281-7"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19106105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Herpes zoster ophthalmicus as a cause of Horner syndrome.","authors":"E F Smith, L Santamarina, A H Wolintz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Herpes zoster ophthalmicus is a disease in which the varicella-zoster virus replicates and produces inflammation in the skin of the face supplied by the sensory branches of the ophthalmic division of the trigeminal nerve. It can also cause a conjunctivitis, keratitis, uveitis, extraocular muscle paralysis, and acute retinal necrosis. We found only a single report of this disease as a cause of Horner syndrome. Here we report a case of herpes zoster ophthalmicus that progressed to a sixth nerve palsy and, subsequently, a Horner syndrome. We discuss how the anatomic relationship of the fifth, sixth, and sympathetic nerves in the cavernous sinus provides a route whereby the varicella-zoster virus may produce a Horner syndrome. To our knowledge this is the first fully documented case of Horner syndrome caused by herpes zoster ophthalmicus.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"250-3"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19105543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Botulinum toxin type A in upper lid retraction of Graves' ophthalmopathy.","authors":"R Ebner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Botulinum toxin type A (BTTA) was injected in the upper lid of 6 patients to reduce palpebral retraction due to Graves' ophthalmopathy. Five unilateral and one bilateral (all female) cases constitute the present series. Injection of 2.5 to 7.5 units of BTTA in the affected lids produced ptosis of 2 to 3 mm in 5 patients. A bilateral case showed a positive but insufficient response by the third injection. An acceptable position of the affected eyelids was maintained for 1 to 8 months. The drug-effect period varied in every patient, regardless of the dose injected, amount of retraction, or endocrine status (hyper, hypo, or euthyroidism) at the moment of treatment. In 5 of 6 patients BTTA provided acceptable upper lid position without cosmetic discomfort. The early results obtained encouraged the use of botulinum toxin in this entity.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"258-61"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19105545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An unusual cause of recurrent vitreous hemorrhage.","authors":"J L Smith","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"293-4"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19106106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ptosis and levator paralysis caused by orbital roof fractures. Three cases with subfrontal epidural hematomas.","authors":"J R Keane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Blows to the forehead resulted in orbital roof fractures and subfrontal epidural hemorrhage in three patients. Neurologic eye signs were limited to ipsilateral paralysis of globe and lid elevation. In the context of an ecchymotic upper lid, these findings indicate local damage to orbital muscles rather than injury to the superior division of the third nerve. Even when such patients are alert, prompt computed tomographic (CT) scanning of the head should be undertaken to rule out an enlarging epidural hematoma.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"225-8"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19105539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Apoplectic optochiasmal syndrome due to intrinsic cavernous hemangioma. Case report.","authors":"J F Hwang, C W Yau, J K Huang, C Y Tsai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 42-year-old man suffered from acute evolving visual loss after drinking alcohol. Consecutive visual field changes suggested a mass within the left optic nerve extending its compression across the chiasm and encroaching on the left optic tract. Computed tomography scanning and magnetic resonance imaging confirmed the presence of an overt hemorrhage, a real apoplectic event of cavernous hemangioma. Cavernous hemangiomas located within the intracranial optic nerve are few. Occult hemorrhage within the confines of the intrinsic vascular tumor resulted in acute visual changes in most reported cases. Overt hemorrhage with blood extravasation beyond the original confines of the intrinsic optochiasmal tumor are rarely reported in the literature. Herein, we report one such case. The clinical course and the predisposing factors are also discussed.</p>","PeriodicalId":77200,"journal":{"name":"Journal of clinical neuro-ophthalmology","volume":"13 4","pages":"232-6"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19105541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}