Frontiers of oral physiology最新文献_第2页

Stability and Retention. 稳定性和保持性。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000353098

L. Will

引用次数: 4

Surgical Methods for the Acceleration of the Orthodontic Tooth Movement. 加速正畸牙齿移动的外科方法。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000382051

K. Almpani, A. Kantarcı

引用次数: 16

Neurologic Regulation and Orthodontic Tooth Movement. 神经调节与正畸牙齿运动。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000351900

S. Kyrkanides, Hechang Huang, R. D. Faber

{"title":"Neurologic Regulation and Orthodontic Tooth Movement.","authors":"S. Kyrkanides, Hechang Huang, R. D. Faber","doi":"10.1159/000351900","DOIUrl":"https://doi.org/10.1159/000351900","url":null,"abstract":"Pain and discomfort are prevalent symptoms among the vast majority of patients with fixed orthodontic appliances and is the most disliked aspect of treatment. The periodontium is a highly innervated structure that also provides the necessary trophic factors, such as nerve growth factor, which promote neuronal survival, maintenance and axonal growth, via interaction with specific nerve surface receptors, such as TrkA. Various types of nerves are found in the periodontium, including thinly myelinated and unmyelinated sensory fibers that express the neuropeptides substance P and calcitonin gene-related peptide among others. Tooth movement activates peripheral sensory nerve endings, which transmit painful signals to the brain after being processed at the trigeminal spinal nucleus, resulting in local expression of pain related genes, such as c-Fos. Concurrently, an attendant inflammatory process is detected in the trigeminal spinal nucleus, including activation of astrocytes, microglia and neurons. This complex neurologic reaction to tooth movement mediates orthodontic pain and also serves a source of neurogenic inflammation exhibited in the trigeminal spinal nucleus and the periodontium. Activated periodontal sensory fibers release neuropeptides in the periodontal environment, which in turn induce a local inflammatory cascade aiding in alveolar bone turnover and tooth movement per se. Control of pain with nonsteroidal anti-inflammatory drugs and other prescription or over-the-counter pain killers effectively reduce this neurologic reaction and alleviate the attendant pain, but also reduce the neurogenic inflammatory component of orthodontic tooth movement causing a slowdown in bone turnover and consequently delaying orthodontic treatment.","PeriodicalId":77140,"journal":{"name":"Frontiers of oral physiology","volume":"18 1","pages":"64-74"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000351900","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64658833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Conclusion and Future Directions. 结论和未来方向。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000351910

A. Kantarcı, Stephen Yen, L. Will

引用次数: 21

Regional Acceleratory Phenomenon. 区域加速现象。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000351897

Carlalberta Verna

{"title":"Regional Acceleratory Phenomenon.","authors":"Carlalberta Verna","doi":"10.1159/000351897","DOIUrl":"https://doi.org/10.1159/000351897","url":null,"abstract":"The regional acceleratory phenomenon (RAP) is a tissue reaction to a noxious stimulus that increases the healing capacities of the affected tissues. It is typical not only of hard tissues such as bone and cartilage, but also of soft tissues. The RAP is characterized by acceleration of the normal cellular activities, as an 'SOS' phenomenon of the body that has to respond to the new perturbation. In the alveolar bone, the RAP is characterized, at a cellular level, by increased activation of the basic multicellular units (BMUs), thereby increasing the remodeling space. At the tissue level, the RAP is characterized by the production of woven bone, with the typical unorganized pattern, that will be reorganized into lamellar bone at a later stage. In the alveolar bone, the RAP occurs typically in the healing process of the alveolar sockets after tooth extraction, in periodontal disease, after surgery and trauma and during orthodontic tooth movement. In relation to orthodontic tooth movement, the RAP can be seen as a tissue response to the mechanical cyclical perturbation that induces the formation of microdamage that has to be removed to avoid their accumulation and the following bone failure. The adaptation to the new orthodontically induced mechanical environment is ensured by an increased activation of the BMU that returns to normal levels after few months.","PeriodicalId":77140,"journal":{"name":"Frontiers of oral physiology","volume":"18 1","pages":"28-35"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000351897","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64658382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 93

Nonsurgical Methods for the Acceleration of the Orthodontic Tooth Movement. 加速正畸牙齿移动的非手术方法。

Frontiers of oral physiology Pub Date : 2016-01-01 DOI: 10.1159/000382048

K. Almpani, A. Kantarcı

引用次数: 30

Tgf-beta regulation of suture morphogenesis and growth. tgf - β对缝线形态发生和生长的调控。

Frontiers of oral physiology Pub Date : 2008-01-01 DOI: 10.1159/0000115038

J. Rawlins, L. Opperman

引用次数: 17

Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations. 颅缝闭锁的遗传学:基因、综合征、突变和基因型-表型相关性。

Frontiers of oral physiology Pub Date : 2008-01-01 DOI: 10.1159/0000115035

M. Passos-Bueno, Andr Eacute A L Serti Eacute, F. Jehee, R. Fanganiello, E. Yeh

{"title":"Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations.","authors":"M. Passos-Bueno, Andr Eacute A L Serti Eacute, F. Jehee, R. Fanganiello, E. Yeh","doi":"10.1159/0000115035","DOIUrl":"https://doi.org/10.1159/0000115035","url":null,"abstract":"Craniosynostosis is a very heterogeneous group of disorders, in the etiology of which genetics play an important role. Chromosomal alterations are important causative mechanisms of the syndromic forms of craniosynostosis accounting for at least 10% of the cases. Mutations in 7 genes are unequivocally associated with mendelian forms of syndromic craniosynostosis: FGFR1, FGFR2, FGFR3, TWIST1, EFNB1, MSX2 and RAB23. Mutations in 4 other genes, FBN1, POR, TGFBR1 and TGFBR2, are also associated with craniosynostosis, but not causing the major clinical feature of the phenotype or with an apparently low penetrance. The identification of these genes represented a great advance in the dissection of the genetics of craniosynostosis in the last 15 years, and today they explain the etiology of about 30% of the syndromic cases. The paucity in the identification of genes associated with this defect has partly been due to the rarity of familial cases. In contrast, very little is known about the molecular and cellular factors leading to nonsyndromic forms of craniosynostosis. Revealing the molecular pathology of craniosynostosis is also of great value for diagnosis, prognosis and genetic counseling. This chapter will review (1) the chromosomal regions associated with syndromic forms of the malformation, (2) the genes in which a large number of mutations have been reported by independent studies (FGFR1, FGFR2, FGFR3, TWIST1 and EFNB1) and (3) the molecular mechanisms and genotype-phenotype correlations of such mutations.","PeriodicalId":77140,"journal":{"name":"Frontiers of oral physiology","volume":"12 1","pages":"107-43"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64394080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 151

Locate, condense, differentiate, grow and confront: developmental mechanisms controlling intramembranous bone and suture formation and function. 定位、凝聚、分化、生长和对抗:控制膜内骨和缝合线形成和功能的发育机制。

Frontiers of oral physiology Pub Date : 2008-01-01 DOI: 10.1159/0000115030

D. Rice, R. Rice

引用次数: 27

The Bmp pathway in skull vault development. 颅骨拱顶发育中的Bmp通路。

Frontiers of oral physiology Pub Date : 2008-01-01 DOI: 10.1159/0000115042

R. Maxson, M. Ishii

引用次数: 30