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Epilepsy research. Supplement最新文献

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Study population selection. 研究人群选择。
Epilepsy research. Supplement Pub Date : 1993-01-01
D M Treiman
{"title":"Study population selection.","authors":"D M Treiman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"125-35"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Handling seizure data: special problems. 处理扣押数据:特殊问题。
Epilepsy research. Supplement Pub Date : 1993-01-01
M W Pierce, V S Shu
{"title":"Handling seizure data: special problems.","authors":"M W Pierce, V S Shu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"175-8"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study agreements and budgets. 研究协议和预算。
Epilepsy research. Supplement Pub Date : 1993-01-01
J S McJilton
{"title":"Study agreements and budgets.","authors":"J S McJilton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"185-91"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visit management: reducing unnecessary paperwork. 访客管理:减少不必要的文书工作。
Epilepsy research. Supplement Pub Date : 1993-01-01
J K Salzmann
{"title":"Visit management: reducing unnecessary paperwork.","authors":"J K Salzmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"223-31"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NIH epilepsy branch trials: budgetary and practical issues. NIH癫痫分支试验:预算和实际问题。
Epilepsy research. Supplement Pub Date : 1993-01-01
M P Jacobs
{"title":"NIH epilepsy branch trials: budgetary and practical issues.","authors":"M P Jacobs","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"239-44"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparing for an FDA audit. 为FDA审核做准备。
Epilepsy research. Supplement Pub Date : 1993-01-01
D Barnes
{"title":"Preparing for an FDA audit.","authors":"D Barnes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"245-50"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical trials performed for the new drug approval process in the United States: standard methods and alternative methods. 在美国为新药批准程序进行的临床试验:标准方法和替代方法。
Epilepsy research. Supplement Pub Date : 1993-01-01
T R Browne
{"title":"Clinical trials performed for the new drug approval process in the United States: standard methods and alternative methods.","authors":"T R Browne","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"31-44"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiepileptic drugs in clinical development. 临床开发中的抗癫痫药物。
Epilepsy research. Supplement Pub Date : 1993-01-01
R E Ramsay, J D Slater
{"title":"Antiepileptic drugs in clinical development.","authors":"R E Ramsay, J D Slater","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"45-67"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Old and new mechanisms of antiepileptic drug actions. 抗癫痫药物作用的新旧机制。
Epilepsy research. Supplement Pub Date : 1993-01-01
M A Dichter
{"title":"Old and new mechanisms of antiepileptic drug actions.","authors":"M A Dichter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>At the present time, between 30% and 50% of individuals with epilepsy continue to have seizures and among those who are considered \"controlled\", a good many unpleasant side effects are endured. It is clear that we need more and better antiepileptic drugs. The virtual explosion in knowledge about the cellular and molecular mechanisms underlying both normal and pathological reactions of the brain provides encouragement that we are on the right path towards developing new, effective and safe agents. Whether we continue to use \"model-based\" screening or \"mechanism-based screening\", or both, we must not go another 14 years without the introduction of a new antiepileptic drug. The problem is too large, our patients are too impatient and our responsibilities are clear.</p>","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternative analyses for antiepileptic drug trials. 抗癫痫药物试验的替代分析。
Epilepsy research. Supplement Pub Date : 1993-01-01
G W Pledger, J T Sahlroot
{"title":"Alternative analyses for antiepileptic drug trials.","authors":"G W Pledger,&nbsp;J T Sahlroot","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77115,"journal":{"name":"Epilepsy research. Supplement","volume":"10 ","pages":"167-74"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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