American biotechnology laboratory最新文献

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PCR amplification using psoralen biotinylated primers: PAGE analysis and direct chemiluminescent detection. 用补骨脂素生物素化引物进行PCR扩增:PAGE分析和直接化学发光检测。
American biotechnology laboratory Pub Date : 1995-09-01
T King
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引用次数: 0
Antibody humanization predicted by computer graphic analysis. 用计算机图形分析预测抗体人源化。
American biotechnology laboratory Pub Date : 1995-08-01
K Ramnarayan, E Skaletsky
{"title":"Antibody humanization predicted by computer graphic analysis.","authors":"K Ramnarayan,&nbsp;E Skaletsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Humanized antibodies continue to be evaluated in clinical trials, and each trial will yield valuable information for the design of the next generation of humanized antibodies. More attention will be given to the use of antibody fragments and the selection of human antibody specificities from phage libraries for human antibody therapeutics. Computer graphic analysis and molecular modeling of antibody structures will continue to be invaluable for predicting structural modifications for humanization of antibodies and for extracting structural information from antigen binding sites that can ultimately lead to small molecule therapeutics.</p>","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"13 9","pages":"26, 28"},"PeriodicalIF":0.0,"publicationDate":"1995-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18649755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forensic applications of gel electrophoresis. 凝胶电泳的法医学应用。
American biotechnology laboratory Pub Date : 1995-08-01
R C Allen, C L Goldberg
{"title":"Forensic applications of gel electrophoresis.","authors":"R C Allen,&nbsp;C L Goldberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"13 9","pages":"8, 10, 12"},"PeriodicalIF":0.0,"publicationDate":"1995-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18649756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid protease screening using ammonium sulfate precipitations and a high-performance centrifuge. 使用硫酸铵沉淀和高性能离心机快速筛选蛋白酶。
American biotechnology laboratory Pub Date : 1995-07-01
S E Little, J T Little
{"title":"Rapid protease screening using ammonium sulfate precipitations and a high-performance centrifuge.","authors":"S E Little,&nbsp;J T Little","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"13 8","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18631069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated DNA purification for fluorescent sequencing. 用于荧光测序的自动DNA纯化。
American biotechnology laboratory Pub Date : 1995-02-01
C Lear
{"title":"Automated DNA purification for fluorescent sequencing.","authors":"C Lear","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"13 3","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"1995-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18767867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laboratory buyer's guide. 实验室买家指南。
American biotechnology laboratory Pub Date : 1995-02-01
{"title":"Laboratory buyer's guide.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"13 2","pages":"6-264"},"PeriodicalIF":0.0,"publicationDate":"1995-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18767910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology: the next opportunity for biotechnology. 纳米技术:生物技术的下一个机遇。
American biotechnology laboratory Pub Date : 1994-12-01
R L Stevenson
{"title":"Nanotechnology: the next opportunity for biotechnology.","authors":"R L Stevenson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"12 13","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18766049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug research needs more support. 药物研究需要更多的支持。
American biotechnology laboratory Pub Date : 1994-12-01
R L Stevenson
{"title":"Drug research needs more support.","authors":"R L Stevenson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"12 13","pages":"4, 6"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18766052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using dyes and filters in a fluorescent imaging system. 在荧光成像系统中使用染料和滤光片。
American biotechnology laboratory Pub Date : 1994-12-01
K B Bechtol, D K Hanzel, B C Liang
{"title":"Using dyes and filters in a fluorescent imaging system.","authors":"K B Bechtol,&nbsp;D K Hanzel,&nbsp;B C Liang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The FluorImager fluorescence imaging system uses monochromatic 488-nm laser light to excite fluorochromes. It contains a built-in 515-nm long-pass filter that rejects excitation laser light, but allows emission light with wavelengths longer than 515 nm to pass through. A fluorochrome appropriate for use in the system is excitable by 488-nm light and emits at least some of its fluorescence at wavelengths longer than 515 nm. Two types of optical filters, long-pass and band-pass, are used in the system. Long-pass filters reject shorter wavelengths and transmit longer wavelengths. The number in the filter name denotes the cutoff wavelength (midpoint of the transition between rejected and transmitted light) for the filter. Band-pass filters transmit a band of wavelengths and reject both shorter and longer wavelengths. The numbers in the filter name denote the center wavelength of the passed band and the width of the band at half maximum transmission. Generally, when scanning for a single fluorochrome, only the built-in 515-nm long-pass filter is needed. An interchangeable filter can be added to decrease the contribution from a broad-spectrum background signal and to attenuate strong fluorochrome signals.</p>","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"12 13","pages":"8-10"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18533299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid detection of immobilized nucleic acids with a hybridization solution. 用杂交液快速检测固定化核酸。
American biotechnology laboratory Pub Date : 1994-12-01
T T Yang, S R Kain
{"title":"Rapid detection of immobilized nucleic acids with a hybridization solution.","authors":"T T Yang,&nbsp;S R Kain","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76989,"journal":{"name":"American biotechnology laboratory","volume":"12 13","pages":"35-6"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18766050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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