{"title":"Pediatric liver transplantation.","authors":"A Dhawan, P Muiesan","doi":"10.1111/j.1442-200x.1998.tb01985.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb01985.x","url":null,"abstract":"Liver transplantation in children has become a treatment of choice for end‐stage liver disease. Both graft and patient survival has significantly improved over the last two decades. The major factor contributing towards improved survival is availability of cyclosporin. Surgical innovations like living related donation has not only increased the donor pool, but has also helped patients in countries where cadaveric donation is not available. Auxiliary liver transplantation has made a significant change to the management of children with liver‐based metabolic disorders and, in selected cases of acute liver failure, immunosuppression can be safely withdrawn once the native liver recovers. However, the complications associated with immunosuppression, such as nephrotoxicity, Iymphoproliferative disease and viral infections, continue to be a matter of great concern. Most children with good graft function enjoy near normal quality of life.","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"525-9"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb01985.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20798869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Niijima, K Takahashi, M Onishi, N Arii, M Saito, K Kuremoto, Y Yamashiro
{"title":"Clinical electroencephalographic study of nine pediatric patients with convulsion induced by the TV animation, Pocket Monster.","authors":"S Niijima, K Takahashi, M Onishi, N Arii, M Saito, K Kuremoto, Y Yamashiro","doi":"10.1111/j.1442-200x.1998.tb01987.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb01987.x","url":null,"abstract":"<p><strong>Background: </strong>To determine the usefulness of a few types of photic stimulation in patients with photo-convulsive response.</p><p><strong>Methods: </strong>A clinical electroencephalographic study was conducted in nine children who developed convulsions and other symptoms while they watched the TV animation and were subsequently treated at the hospital. Photic stimulation was applied with their eyes open or closed. Another photic stimulation was applied with the video tape of the animation.</p><p><strong>Results: </strong>A photoparoxysmal response (PPR) was never seen in the electroencephalographs (EEG) in any of these patients when photic stimulation was applied with their eyes closed, while PPR was seen in three of seven patients when photic stimulation was applied with their eyes open. Two patients (siblings) showed no specific abnormality when photic stimulation was applied with their eyes either open or closed. However, myoclonus and PPR appeared when the EEG was conducted while they watched the video tape of the animation under supervised conditions.</p><p><strong>Conclusions: </strong>In a society where people are exposed to abundant TV games, TV animation or videos, self-restraint or regulations of frequent use of flickering scenes is thought to be necessary. However, it is also thought to be necessary to conduct EEG by applying photic stimulation, not only with the eyes closed, but also with the eyes opened or by applying flickering red light stimulation, which is emitted from a strong light source, or a combination of two colors, such as red and blue or red and green, in patients with suspected photosensitivity.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"544-9"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb01987.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20798871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A K Adhikary, Y Zhou, J Kakizawa, J Numaga, S Akihara, Z Y Fang, H Ushijima
{"title":"Distribution of rotavirus VP4 genotype and VP7 serotype among Chinese children.","authors":"A K Adhikary, Y Zhou, J Kakizawa, J Numaga, S Akihara, Z Y Fang, H Ushijima","doi":"10.1111/j.1442-200x.1998.tb02008.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb02008.x","url":null,"abstract":"","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"641-3"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb02008.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20800399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Furusho, K Yamaguchi, Y Ikura, T Kogure, M Suzuki, S Konishi, G Simizu, Y Nakayama, K Itoh, Y Sakamoto, A Ishikawa, S Ezaki, J Nawata, K Kumagai
{"title":"Patient background of the Pokemon phenomenon: questionnaire studies in multiple pediatric clinics.","authors":"J Furusho, K Yamaguchi, Y Ikura, T Kogure, M Suzuki, S Konishi, G Simizu, Y Nakayama, K Itoh, Y Sakamoto, A Ishikawa, S Ezaki, J Nawata, K Kumagai","doi":"10.1111/j.1442-200x.1998.tb01988.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb01988.x","url":null,"abstract":"<p><p>Many children in Japan developed various neuropsychological problems, including seizures, while watching the program Pocket Monster, televised on 16 December 1997. To examine the basis for this incident, we have performed a survey of volunteering children and their parents who visited our pediatric clinics for other reasons from 8 January to 28 February 1998. Children and their parents filled out questionnaires. Among the total of 662 children surveyed, the great majority (603, 91.1%) was found to have watched the Pocket Monster program and 30 individuals (5.0% of viewers) complained of variable degrees of neuropsychological abnormalities. These included seizures (two cases), headache (nine cases), nausea (eight cases), blurred vision (four cases), vertigo (two cases), dysthymia (two cases) and vomiting (one case). Nearly half (14) of these children developed symptoms during or immediately after watching the program, while the remainder did so later. Representative cases are reported and other statistical aspects are discussed.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"550-4"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb01988.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20798872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Tanaka, N Onodera, R Ito, A Higuchi, Y Suzuki, N Monma, S Waga
{"title":"Subclinical Sjögren's syndrome: a significant 67gallium accumulation in the orbits and parotid glands.","authors":"H Tanaka, N Onodera, R Ito, A Higuchi, Y Suzuki, N Monma, S Waga","doi":"10.1111/j.1442-200x.1998.tb02003.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb02003.x","url":null,"abstract":"<p><p>An 8-year-old girl with hypergammaglobulinemia showed an abnormal 67gallium accumulation in the orbits and parotid glands. Although she did not have any subjective siccant complaints, reported typical histopathological and sialographic changes suggesting Sjögren's syndrome (SjS) were observed in the salivary glands. Gallium scintigram might be a valuable and non-invasive diagnostic tool in the diagnosis of children with SjS without sicca symptoms.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"621-3"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb02003.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20799795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Hiraiwa, M Hamazaki, S Tsuruta, H Hattori, J Mimaya, S Hasegawa, S Kohno, K Aoki
{"title":"Infantile hemangioendothelioma of the thymus with massive pleural effusion and Kasabach--Merritt syndrome: histopathological, flow cytometrical analysis of the tumor.","authors":"H Hiraiwa, M Hamazaki, S Tsuruta, H Hattori, J Mimaya, S Hasegawa, S Kohno, K Aoki","doi":"10.1111/j.1442-200x.1998.tb01999.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb01999.x","url":null,"abstract":"<p><p>Infantile hemangioendothelioma of the thymus is a rare disease. We describe a patient who developed a large anterior mediastinal mass, severe thrombocytopenia and massive pleural effusion at 1 month of age. Glucocorticosteroid and irradiation therapy had no effect on either the tumor size or clinical symptoms and the tumor was resected subtotally. Three months after the subtotal resection, the remaining tumor had almost disappeared and the symptoms had resolved. The patient has now been well for 1 year after surgery without evidence of recurrence. The tumor tissue was characterized by prominent vascular endothelial proliferation intermixed with a normal thymic structure, producing a picture consistent with that of an infantile hemangioendothelioma in the thymus. Immunohistochemically, the tumor cells showed positive staining for vimentin, factor VIII and CD34. The DNA stemline and proliferative activity were examined by flow cytometry, which revealed a diploid stemline with a low growth fraction. DNA content and cell cycle analyses of the tumor tissue may be useful for predicting the biological behavior of the tumor.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"604-7"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb01999.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20799791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of body position on tidal volume and minute ventilation in very low birthweight infants.","authors":"Y Itakura, Y Ogawa","doi":"10.1111/j.1442-200x.1998.tb01989.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb01989.x","url":null,"abstract":"<p><strong>Background: </strong>To progress the clinical treatment of neonates, especially in the management of respiration, we have to be able to measure their pulmonary function appropriately. Various methods have been developed, but little is known about the pulmonary function of very low birthweight infants (VLBWI) because of the difficulty in taking their measurements with existing equipment. We have developed a very low dead space pneumotachograph to measure lung function in VLBWI.</p><p><strong>Methods and results: </strong>We used our pneumotachograph on 30 infants each weighing less than 1500 g at birth. The infants were intubated with endotracheal tubes of 2.5 or 2.0 mm diameter to measure tidal volume and minute ventilation in the prone and supine position. The tidal volume in the supine position was 6.99 +/- 0.42 mL/kg and 7.58 +/- 0.38 mL/kg in the prone position (mean +/- SE). The tidal volume was significantly larger in the prone than the supine position (P < 0.05). However, no significant difference was observed in minute ventilation and respiratory rates.</p><p><strong>Conclusion: </strong>The tidal volume significantly increased in the prone position in VBLWI, confirming the previous observation of larger healthy infants is also applicable to the very low birthweight infants.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"555-7"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb01989.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20799343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trisomy 6 in a childhood acute mixed lineage leukemia.","authors":"N Onodera, T Nakahata, H Tanaka, R Ito, T Honda","doi":"10.1111/j.1442-200x.1998.tb02002.x","DOIUrl":"https://doi.org/10.1111/j.1442-200x.1998.tb02002.x","url":null,"abstract":"<p><p>The patient is a 12-year-old boy with acute mixed lineage leukemia (AMLL) and with a rare karyotype of trisomy 6. He was referred to our hospital with gingival swelling, bleeding at the conjunctiva and huge hepatosplenomegaly. Complete blood count revealed leukocytosis with 79% blasts, anemia and thrombocytopenia. Bone marrow examination revealed 82.5% blasts which were morphologically judged as M1 according to the French-American-British classification. Immunophenotyping of leukemic cells showed the presence of CD2, CD7, CD19 and CD13 antigens, suggesting the diagnosis of AMLL. Cytogenetic analysis revealed a single abnormal karyotype of 47,XY,+6,add(15)(q22) which was successfully detected by fluorescence in situ hybridization (FISH) with the probe mapping at the alpha-satellite region of chromosome 6. Although the patient was treated with several chemotherapy regimens, he could not achieve complete remission and he died of progressive disease 11 months after admission. Fluorescence in situ hybridization analysis was very informative in assessing the residual leukemic cells in interphase during his clinical course.</p>","PeriodicalId":76975,"journal":{"name":"Acta paediatrica Japonica : Overseas edition","volume":"40 6","pages":"616-20"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1442-200x.1998.tb02002.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20799794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}