K D Kyun, K S Yun, J S Young, C C Pyoung, S S Heui
{"title":"[Development of minocycline containing polycaprolactone film as a local drug delivery].","authors":"K D Kyun, K S Yun, J S Young, C C Pyoung, S S Heui","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Local drug delivery by using biocompatible polymers has been developed in the treatment of periodontitis for many years. The purpose of this study was to examine the release kinetics of minocycline from monolithic film prepared from polycaprolactone and polyethylene glycol and to examine the antimicrobial activity in vitro. Polycaprolactone (Mwt 60,000), polyethylene glycol and minocyline was dissolved by chloroform, which was vigorously stirred for 24 hours and it was dried in vacuum chamber. The thickness of cast films containing 20%, 30% and 40% minocycline was 200 +/- 10 microns. Release rate of minocycline from the film was measured by means of a UV spectrophotometer. In vitro releasing test, each film showed a large burst effect within first two and three hours and a steady state release kinetic at the rate of 4-8 micrograms/cm/hour for 7 days. In antimicrobial test, each sample (one fourth inch in diameter) sunk in the broth that had been innoculated with periodontopathic bacteria showed growth inhibitory activity after 48 hr anaerobic incubation. In cytotoxicity test, there was no significant cytotoxic effect in casting film to human gingival fibroblast. This study showed that, by embedding minocycline in polycaprolactone, it is feasible to obtain substained release of the drug within the periodontal pocket for seven days and should be useful tool for elimination of pathogenic microflora from periodontal pocket or reducing inflammation in periodontal disease.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 3","pages":"279-90"},"PeriodicalIF":0.0,"publicationDate":"1990-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13287614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A clinical study on the adenoid cystic carcinoma in oral cavity].","authors":"M Byung","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two cases of adenoid cystic carcinoma occurred on the palate are reported. They were female and aged 65 and 69 year. They showed expansile growth in association with the bony destruction of maxillary sinus wall. Histologically the case 1 had cribriform pattern and the case 2 had cribriform and tubular pattern, and exhibited perineural invasion of tumor cells in both cases. The radical surgery were conducted, and there were no lymph node metastasis and recurrence.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 3","pages":"259-64"},"PeriodicalIF":0.0,"publicationDate":"1990-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13125644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Soft X-ray study on fetal cranio-facial growth and development].","authors":"W S Yang, C H Suhr, D S Nahm, Y I Chang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study was undertaken to ascertain the changes of fetuses in craniofacial dimension and to evaluate the growth and development during fetal period. Lateral cephalograms by soft X-ray were taken from 64 fetuses and were measured in linear and angular aspects. The following conclusions were obtained. 1. The linear increase rates of anterior cranial base length exceeded those of the posterior cranial base length. 2. Growth increments on horizontal dimension were greater than vertical dimension in the maxilla. 3. The cranial base angle was almost constant after fetal period 13 weeks with the average angle of 130 degrees. 4. The angle between anterior cranial base and palatal plane was decreased gently during fetal period.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 3","pages":"265-77"},"PeriodicalIF":0.0,"publicationDate":"1990-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13287613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Case reports of orthodontic treatment related to facial patterns].","authors":"C J Hwang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This present paper describes 3 clinical cases which were treated according to facial patterns. First, facial pattern of each patient was classified by Ricketts's analysis and then, treatment objects and mechanics were determinded. Brachyfacial patterns are showed a resistant to mandibular rotation during treatment can accept a more prutrusion denture and primary treatment by nonextraction, whereas dolichofacial patterns were tended to open during treatment require a more retracted denture in order to assure post-treatment stability. Brachyfacial pattern would better treat to use extrusive force system, whereas dolichofacial pattern treat to use intrusive force system with head gear and intermaxillary elastics.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 2","pages":"193-211"},"PeriodicalIF":0.0,"publicationDate":"1990-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13284947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical application of intermaxillary traction for temporomandibular disorders].","authors":"H Chung, S C Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Occlusal splint has been usually used for TMJ arthrosis as a conservative treatment, but the range of its application is narrow and less effective. This study is to evaluate the effect of the pivoting splint with intermaxillary rubber traction, to report the results of the pivoting splint with intermaxillary rubber traction which was used 24 patients.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 2","pages":"175-9"},"PeriodicalIF":0.0,"publicationDate":"1990-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13284975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A scanning electron microscope study comparing the cleansing effect of the irrigating solutions and irrigating systems].","authors":"D Y Kim, G W Choi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to compare the effect of various irrigating solutions and irrigating debris and the smear layer from the walls of instrumented root canals. 20 single-rooted teeth were biomechanically instrumented to size 40 K-file using sterile saline. And then the teeth were divided into 4 groups and 5 teeth in each group. Groups were irrigated as follows: Group 1: Teeth were irrigated with 20 ml of sterile saline. Group 2: Teeth were irrigated with 10 ml of 3% H2O2 and 10 ml of 2.5% NaOCl using the syringe. Group 3: Teeth were irrigated with 10 ml of 3% H2O2 and 10 ml of 2.5% NaOCl using the ENAC. Group 4: Teleth were irrigated with 10 ml of 17% EDTA and 10 ml of 2.5% NaOCl using the Endo-mate. All specimens were viewed at the cervical, middle, and apical thirds of the root canals for evaluation of the cleaning effect with the scanning electron microscope. The results were as follows: 1. The Endo-mate with EDTA and NaOCl solutions was the most efficient in cleaning the cervical and middle thirds of the root canal. 2. There was no difference between the irrigating solutions and irrigating systems in the cleaning effect at the apical third of the root canal.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 2","pages":"181-92"},"PeriodicalIF":0.0,"publicationDate":"1990-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13284976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A study of occlusion phase during mastication in complete denture patients].","authors":"C W Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Author examined the chewing patterns of 10 complete denture wearers with LED mandibular tracking device, and analyzed the average cycle time, average occlusion time and the ratio of average time/average cycle time during chewing occlusion various test foods-standardized carrot and ham, the results were as follow: 1. The average cycle time of chewing carrot was longer than that of chewing ham. 2. The average occlusion time of chewing carrot was longer than that of chewing ham. 3. The ratio of average occlusion time/average cycle time of chewing ham was greater than that of chewing carrot. 4. During chewing carrot or ham, there was an increasing tendency in occlusion time and ratio of occlusion time/cycle time.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 1","pages":"117-23"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13284972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Experimental studies on wound healing of the jaw bone fracture].","authors":"I W Nam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author has studied on wound healing of the jaw bone fractures in 5 Malaysian monkeys aging around 2 years and weighing about 3 Kg. For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring. The experimental animals were sacrificed on the 1st, 2nd, 3rd, 4th and 5th week thereafter, and the fracture sites were obtained to make microscopic slides stained with Hematoxylin-Eosin, and Van Gieson method. The results obtained were as follows: 1. The blood of hematoma situated in fractured crevice are getting replaced with granulation tissue 1 week after fracture. 2. The granulation tissue occurred in fractured crevice are getting replaced with connective tissue as bone matrix 2 weeks after fracture. 3. Immature new bone formation with bony trabeculation formed 3 weeks after fracture. 4. The secondary bony callus with abundant osteoblasts and osteocytes in bone matrix formed 4 weeks after fracture. 5. The fractured wound completely healed with a new bone formation 5 weeks after fracture.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"28 1","pages":"109-15"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13284971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Case report on the treatment of the Angle's Class III malocclusion using Wunderer Activator and multi-vertical loop arch wire].","authors":"T H Tan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Class III malocclusions are usually related to growth and mandibular posture, so we must detect the exact causes of mesioclusion i.e., functional, skeletal, or combind from the start. Functional mesioclusion is easily managed but skeletal mesioclusion is usually more difficult than functional cases. The author and coworkers treated this case using the Wunderer Activator and TMA multivertical loop arch wire. Therefore, we got good results and the results were as follows. 1. Anterior cross-bite was corrected, therefore facial profile was improved. 2. Posterior occlusal seating was improved. 3. Down and backward rotation of mandible occurred.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"27 12","pages":"1129-42"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13633386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Study on the changes in the upper airway following osteotomy for the mandibular prognathism].","authors":"D K Lee, S K Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study was designed to compare pre-operation, immediate post-operation and over 6 month's follow-up for the mandibular prognathism in order to investigate the changes in the upper airway following mandibular osteotomy. The subjects were 18 patients. Their lateral cephalograms were taken pre-operatively, immediate post-operatively and over 6 months after operation and traced and analysed based on 10 selected items. The following conclusions were reached. 1) The downward displacement of the hyoid bone was recognized right after operation. (P less than 0.01) The hyoid bone tended to move to the original position in male group but not in female group. (P less than 0.01, P greater than 0.05) 2) The distance between the body of hyoid and posterior pharyngeal wall remained constant postoperatively (P greater than 0.05) 3) The distance between the body of hyoid and Menton was found to be shortened right after operation and remained constant thereafter. (P less than 0.01, P greater than 0.05) 4) The distance between the palate and the dorsum of tongue remained constant postoperatively. (P greater than 0.05) 5) The distance between the root of tongue and posterior pharyngeal wall was found to be shortened right after operation and remained constant thereafter. (P less than 0.01, P greater than 0.05) 6) APDI, SN-Pog, SNB and ANB remained constant during over 6 month's follow-up. (P greater than 0.05) 7) Relapse was found to show no correlation to other measurements.</p>","PeriodicalId":76952,"journal":{"name":"Taehan Ch'ikkwa Uisa Hyophoe chi","volume":"27 12","pages":"1143-53"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13633387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}