[Experimental studies on wound healing of the jaw bone fracture].

Taehan Ch'ikkwa Uisa Hyophoe chi Pub Date : 1990-01-01
I W Nam
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Abstract

The author has studied on wound healing of the jaw bone fractures in 5 Malaysian monkeys aging around 2 years and weighing about 3 Kg. For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring. The experimental animals were sacrificed on the 1st, 2nd, 3rd, 4th and 5th week thereafter, and the fracture sites were obtained to make microscopic slides stained with Hematoxylin-Eosin, and Van Gieson method. The results obtained were as follows: 1. The blood of hematoma situated in fractured crevice are getting replaced with granulation tissue 1 week after fracture. 2. The granulation tissue occurred in fractured crevice are getting replaced with connective tissue as bone matrix 2 weeks after fracture. 3. Immature new bone formation with bony trabeculation formed 3 weeks after fracture. 4. The secondary bony callus with abundant osteoblasts and osteocytes in bone matrix formed 4 weeks after fracture. 5. The fractured wound completely healed with a new bone formation 5 weeks after fracture.

颌骨骨折创面愈合的实验研究。
作者对5只年龄在2岁左右,体重在3公斤左右的马来西亚猴子颌骨骨折的伤口愈合进行了研究。在实验研究中,采用700号裂隙骨钉对马来西亚猴下颌骨角至乙状骨切迹斜向截骨进行骨折,并采用骨间钢丝对其进行复位固定。实验动物于术后第1、2、3、4、5周处死,取骨折部位,采用苏木精-伊红染色和Van Gieson法制作显微载玻片。实验结果如下:1。骨折后1周,位于骨折间隙的血肿血逐渐被肉芽组织所取代。2. 骨折后2周,骨折缝隙内的肉芽组织逐渐被结缔组织取代,成为骨基质。3.骨折后3周未成熟的新骨形成伴骨小梁形成。4. 骨折后4周,骨基质中成骨细胞和骨细胞丰富的继发性骨痂形成。5. 骨折后5周,骨折创面完全愈合,新骨形成。
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