American Journal of Biomedical Sciences最新文献_第10页

Geranylgeranylacetone Induces HPS70 and Protects Cochlear Tissues from in Vitro Acute Noise Trauma 香叶酮诱导HPS70对体外急性噪声损伤耳蜗组织的保护作用

American Journal of Biomedical Sciences Pub Date : 2019-10-01 DOI: 10.5099/aj190400255

A. Shoman, Mona Maher

引用次数: 0

Evaluation of Antioxidant Parameters in Contraceptive Users in Family Planning Centres in Kaduna State, Nigeria 尼日利亚卡杜纳州计划生育中心避孕使用者抗氧化参数评价

American Journal of Biomedical Sciences Pub Date : 2019-10-01 DOI: 10.5099/aj190400226

E. Bartimaeus, Maria Ogochukwu Egbuna, Z. Jeremiah, S. U. Ken-Ezihuo

引用次数: 0

A Novelty-Induced Integrated Environmental Challenge to Assess Sedative-Anxiolytic Potential of Lychee (Litchi Chinensis) Honey 新颖诱导的综合环境挑战评估荔枝蜂蜜镇静抗焦虑潜能

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190300120

M. Billah, M. A. Rayhan, S. Yousuf, Kashfia Nawrin, N. Jahan, Elmabruk M. Khengari

引用次数: 0

A Broad Evaluation of Left Breast Radiotherapy 左乳房放射治疗的广泛评价

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190200153

Aime M. Gloi

引用次数: 2

Vaspin Improves Experimental Isoproterenol-induced Heart Failure in Rats Vaspin改善实验性异丙肾上腺素诱导的大鼠心力衰竭

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190300141

M. Suzan, M. Moursi, M. Wesam, M. Ashour, M. A. Radwa, M. D. Elbelbesy

引用次数: 2

Anti- Asprosin: A Potential Protective Role Against the Progression of Diabetic Nephropathy in Type 2 Diabetic Rats 抗Asprosin:对2型糖尿病大鼠糖尿病肾病进展的潜在保护作用

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190300183

H. A. E. Kattawy, W. Ashour

引用次数: 4

Sero-reactivity and Molecular Studies on Subjects with Malaria Immunity and Susceptibility in An Endemic Region 某流行地区疟疾免疫易感性人群的血清反应性和分子研究

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190300172

A. Abubakar, S. Nassar, T. Adeniyi, Olubisi Janet Soladoye

引用次数: 0

Study of Visfatin Level and Its Relation to Some Histopathological Changes of Placentae in Preeclampsia 子痫前期胎盘Visfatin水平及其与组织病理学变化关系的研究

American Journal of Biomedical Sciences Pub Date : 2019-07-01 DOI: 10.5099/aj190300130

M. Megahed, S. M. Dawoud, A. I. El-Sarha, M. Fayed, M. I. Ahmed

{"title":"Study of Visfatin Level and Its Relation to Some Histopathological Changes of Placentae in Preeclampsia","authors":"M. Megahed, S. M. Dawoud, A. I. El-Sarha, M. Fayed, M. I. Ahmed","doi":"10.5099/aj190300130","DOIUrl":"https://doi.org/10.5099/aj190300130","url":null,"abstract":"The objective of the present study was to measure the serum level of visfatin in preeclamptic Egyptian pregnant women and the possible relation of visfatin level to each of the measured insulin resistance, body mass index and histopathological changes of the placenta included in this study. The study population consisted of 30 preeclamptic patients and 30 matched healthy pregnant women during the third trimester. The present study results revealed that preeclamptic mothers had a significant increase in insulin resistance value than normal pregnant women with no significant difference in this value between mild and severe preeclamptic sub-groups. Regarding visfatin level, there was a highly significant increase in visfatin level in preeclamptic women compared with healthy controls and also increase in severe than mild preeclamptic sub-groups. Correlation analysis presented a significant negative correlation between maternal visfatin levels versus HOMA-IR among preeclamptic group, but no relation had been found between visfatin levels and body mass index among preeclamptic mothers. Histopathological examination of placentae revealed that infarctions, atherosis, hyalinized areas and Tenny Parkers changes were significantly increased in preeclamptic group than control group. The present study did not find any correlations between visfatin levels versus histopathological changes in placentae among preeclamptic mothers. Hypervisfatinemia may be one of the possible etiologies of preeclampsia. Visfatin might be part of a feedback mechanism improving insulin sensitivity. Preeclamptic placentae exhibited definite histopathological changes which may be attributed to the vascular insufficiency of placenta.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84612351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell signaling in yeast: A mini review 酵母细胞信号传导:一个小回顾

American Journal of Biomedical Sciences Pub Date : 2019-04-17 DOI: 10.3126/JBS.V5I2.23634

N. N. Shipingana, N. Raghu, S. Gowda, Gopenath Ts, M. Ranjith, A. Gnanasekaran, Mythreye Karthikeyan, B. Roy, B. Pugazhandhi, P. Pradeep, S. Balasubramanian, Kanthesh M. Basalingappa

{"title":"Cell signaling in yeast: A mini review","authors":"N. N. Shipingana, N. Raghu, S. Gowda, Gopenath Ts, M. Ranjith, A. Gnanasekaran, Mythreye Karthikeyan, B. Roy, B. Pugazhandhi, P. Pradeep, S. Balasubramanian, Kanthesh M. Basalingappa","doi":"10.3126/JBS.V5I2.23634","DOIUrl":"https://doi.org/10.3126/JBS.V5I2.23634","url":null,"abstract":"Background: Understanding cellular mechanism of communication is the main goal of systems biology. Unicellular yeasts are effective model to understand the molecular interactions that generate cell polarity induced by external inputs. The mechanisms of many extracellular stimuli are induced by complexes of cell surface receptors, G proteins. The mechanisms of many extracellular stimuli are induced by complexes of cell surface receptors, G proteins and mitogen activated protein (MAP) kinase complexes. Many components, their interrelationships, and their regulators of these mechanisms were initially identified in yeast. A complex web of sensing mechanisms and cooperation among signaling networks such as a cyclic adenosine monophosphate dependent protein kinase, mitogen-activated protein kinase cascade and 5-adenosine monophosphate activated protein kinase induce various changes in physiology, cell polarity, cell cycle progression and gene expression to achieve differentiation. Ras-cAMP pathway explained in yeast model with signalling function of the oncogenic mammalian Ras protein. So studies on yeast cells may enlighten some underlying mechanism which will be beneficial to understand the mechanisms of disease.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83070402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro anti-bacterial activity of Tinospora cordifolia leaf extract and its phytochemical screening 青藤叶提取物体外抑菌活性及植物化学筛选

American Journal of Biomedical Sciences Pub Date : 2019-04-17 DOI: 10.3126/JBS.V5I2.23633

B. Praiwala, S. Priyanka, N. Raghu, N. Gopenath, A. Gnanasekaran, M. Karthikeyan, R. Indumathi, N. Ebrahim, B. Pugazhandhi, P. Pradeep, M. Ranjith, S. Balasubramanian, Kanthesh M. Basalingappa

{"title":"In vitro anti-bacterial activity of Tinospora cordifolia leaf extract and its phytochemical screening","authors":"B. Praiwala, S. Priyanka, N. Raghu, N. Gopenath, A. Gnanasekaran, M. Karthikeyan, R. Indumathi, N. Ebrahim, B. Pugazhandhi, P. Pradeep, M. Ranjith, S. Balasubramanian, Kanthesh M. Basalingappa","doi":"10.3126/JBS.V5I2.23633","DOIUrl":"https://doi.org/10.3126/JBS.V5I2.23633","url":null,"abstract":"Background: Antimicrobial resistance is the main concern worldwide to combat infectious. Over the years studies on leaf extracts Tinospora cordifolia have demonstrated the potent role its antibacterial property. The current study is an attempt to test its antibacterial property against Escherichia coli cell division. \u0000Material and methods: Phytochemical screening assay of T. cordifolia leaf extract was done using standard procedure and the results showed the presence of alkaloid, carbohydrate, terpenoid, steroid, tannin, amino acid, flavonoid and glycoside components. \u0000Results: HPLC analysis revealed the presence of berberine in T. cordifolia leaf extract. Further E. coli cells were treated with berberine to study its efficacy in inhibiting cell division. Antibacterial assay was performed by using disc diffusion method. \u0000Conclusion: Among aqueous, methanolic, ethanolic, chloroform, hexane and acetone extract only methanolic extract showed zone of inhibition.","PeriodicalId":7690,"journal":{"name":"American Journal of Biomedical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88930440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7