Zeitschrift fur Parasitenkunde (Berlin, Germany)最新文献

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Effect of UV-irradiation, spleen cells and MLN cells on protective immunity against Angiostrongylus cantonensis infection in mice. 紫外线照射、脾细胞和MLN细胞对小鼠抗广州管圆线虫感染保护性免疫的影响。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00931149
V R Kamath, S Menon, D M Renapurkar
{"title":"Effect of UV-irradiation, spleen cells and MLN cells on protective immunity against Angiostrongylus cantonensis infection in mice.","authors":"V R Kamath,&nbsp;S Menon,&nbsp;D M Renapurkar","doi":"10.1007/BF00931149","DOIUrl":"https://doi.org/10.1007/BF00931149","url":null,"abstract":"<p><p>The UV-irradiated larvae of Angiostrongylus cantonensis were used for inducing immunity in mice. A single oral dose of 100 infective UV-irradiated larvae exposed for 5 min or 15 min induced 91% and 97% protection against subsequent infection. Adoptive protection against A. cantonensis could also be transferred by spleen and mesenteric lymph node cells obtained from vaccinated mice.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 2","pages":"221-6"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00931149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14825326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The life cycle of Brachylaima ruminae n. sp. (Trematoda: Brachylaimidae), a parasite of rodents. 啮齿动物的一种寄生虫——反刍短臂线虫的生活史。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925095
S Mas-Coma, I Montoliu
{"title":"The life cycle of Brachylaima ruminae n. sp. (Trematoda: Brachylaimidae), a parasite of rodents.","authors":"S Mas-Coma,&nbsp;I Montoliu","doi":"10.1007/BF00925095","DOIUrl":"https://doi.org/10.1007/BF00925095","url":null,"abstract":"<p><p>The life cycle of Brachylaima ruminae n.sp. (Trematoda: Brachylaimidae), a duodenal parasite of rodents on the Mediterranean island of Formentera (Spain) is elucidated. The new species follows a terrestrial triheteroxenous life cycle. Eggs passed in the faeces of the definitive host must be ingested by a specific first intermediate host, the land snail Rumina decollata. Branched cercariogenous sporocysts develop in the digestive gland. Microcercous cercariae come out through the terminal birth pores of the branches. Cercariae shed by the snail are terrestrial, crawling on humid substratum. They contact the second intermediate host, another land snail, principally the species R. decollata and less frequently slugs and Helicids. Cercariae enter via the excretory pore and kidney duct to their specific final location, the kidney. Unencysted metacercariae develop in the kidney (also, less frequently, in the pedal glands) to the mature, infective stage. Infective metacercariae infest the definitive host when ingested together with the snail.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 6","pages":"739-53"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14915939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 36
Immunological memory and lymphoblast-migration in mice infected with Hymenolepis nana. 小膜膜绦虫感染小鼠的免疫记忆和淋巴细胞迁移。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00928750
C Palmas, G Bortoletti, M Conchedda, F Gabriele
{"title":"Immunological memory and lymphoblast-migration in mice infected with Hymenolepis nana.","authors":"C Palmas,&nbsp;G Bortoletti,&nbsp;M Conchedda,&nbsp;F Gabriele","doi":"10.1007/BF00928750","DOIUrl":"https://doi.org/10.1007/BF00928750","url":null,"abstract":"<p><p>The presence of small cells carrying memory and lymphoblast migration in C57 Bl/6N inbred mice with the intestinal parasite Hymenolepis nana were investigated. Hymenolepis nana egg-infection stimulated an enhanced accumulation of mesenteric lymphoblasts at days 3, 6 and 9 after infection; lymphoblasts accumulated selectively in the mesenteric nodes (MLN) of mice suggesting a cell-trapping effect. The migration was studied using lymphoblasts from non-infected donors. Spleen cells and MLNC collected from donor mice 30 days after a primary infection and enriched for T cells were able to transfer an adoptive immunity, by contrast unseparated cells were uneffective. This result provides preliminary evidence for the existence of T memory cells in the spleen and in the mesenteric nodes.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 3","pages":"397-403"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00928750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14610962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Fecundity of Litomosoides carinii (Nematoda, Filarioidea) in vivo and in vitro. carinii(线虫纲,丝状总科)体内和体外繁殖力的研究。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00927743
J Mössinger, P Wenk
{"title":"Fecundity of Litomosoides carinii (Nematoda, Filarioidea) in vivo and in vitro.","authors":"J Mössinger,&nbsp;P Wenk","doi":"10.1007/BF00927743","DOIUrl":"https://doi.org/10.1007/BF00927743","url":null,"abstract":"<p><p>Several parameters concerning the reproduction of Litomosoides carinii were assessed using quantitatively infected cotton rats (Sigmodon hispidus). The course of embryogenesis from the fertilization of eggs to the delivery of the first microfilariae was observed by daily autopsies during prepatency. The duration of embryogenesis in vivo could thus be determined as 18 +/- 2 days. The contents of embryos in the uteri of female worms had been examined at various intervals. At the onset of patency 7-8 weeks p.i. the females were 71 +/- 6 mm long and on average contained 308 X 10(3) embryos/female, of which 19% were pathologically altered. In the middle of patency 16-20 weeks p.i. the females had grown up to 100 +/- 11 mm in length and now contained 509 X 10(3) embryos/female, 25% of them were pathologically altered, the others were normally developed. A positive correlation between the body length of a female worm and its number of embryos in utero was evident. Additionally the percentage of pathologically altered embryos was increased with respect to the age of the worms. The calculated fecundity of a female L. carinii in vivo of around 20 X 10(3) microfilariae/female per day had been confirmed with worms maintained in vitro. Three combinations of media and serum supplements were used and their influence on embryogenesis evaluated.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 1","pages":"121-31"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00927743","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14638366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Assessment of the in vitro growth of Plasmodium falciparum using fluorometry. 用荧光法评价恶性疟原虫体外生长。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925480
J Tamura, S Waki
{"title":"Assessment of the in vitro growth of Plasmodium falciparum using fluorometry.","authors":"J Tamura,&nbsp;S Waki","doi":"10.1007/BF00925480","DOIUrl":"https://doi.org/10.1007/BF00925480","url":null,"abstract":"<p><p>The growth of Plasmodium falciparum in vitro was quantitatively assessed by applying fluorometry using ethidium bromide. The fluorescence intensity of parasites stained with this dye was found to parallel the uptake of 3H-hypoxanthine into nucleic acids during one growth cycle of development. The assay system can be used as a substitute of morphological and radiometric methods in drug-sensitivity tests and for the screening of antimalarials.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 5","pages":"595-7"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925480","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14657090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Studies of murine malaria antigens using monoclonal antibodies. Production, selection, and characterization of antibodies. 利用单克隆抗体研究小鼠疟疾抗原。抗体的产生、选择和鉴定。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925481
G Holmquist, P Borwell, A R Cattan, H Wigzell
{"title":"Studies of murine malaria antigens using monoclonal antibodies. Production, selection, and characterization of antibodies.","authors":"G Holmquist,&nbsp;P Borwell,&nbsp;A R Cattan,&nbsp;H Wigzell","doi":"10.1007/BF00925481","DOIUrl":"https://doi.org/10.1007/BF00925481","url":null,"abstract":"<p><p>A panel of ten monoclonal antibodies made against Plasmodium chabaudi and Plasmodium yoelii infected mouse erythrocytes were used for characterization of antigens present in murine malaria. Screening of the antibodies in ELISA with different fractions of infected erythrocytes revealed both species-specific and fraction-specific monoclonal antibodies (MAbs), but also MAbs cross-reacting between the species. Two MAbs bound normal erythrocyte components. Subcellular localization of the target antigens was studied by immunofluorescence and their molecular identity by immunoblotting after SDS-PAGE. Of the MAbs to P. yoelii, one reacted with a cytoplasmic granule component of 137 k and two others reacted with vacuole-associated antigens of 26 k and 25/70/73 k, respectively. The latter antibodies cross-reacted with P. chabaudi antigens. Of the MAbs to P. chabaudi, all were species specific, one reacting with parasite surface antigens of 79 and 250 k and two with a vacuole-associated antigen of 70 k.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 5","pages":"599-607"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925481","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14657091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The immunocytochemical demonstration of Toxoplasma antigen in the brains of congenitally infected mice. 先天性感染小鼠脑内弓形虫抗原的免疫细胞化学证明。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925482
J Hay, D I Graham, G N Dutton, S Logan
{"title":"The immunocytochemical demonstration of Toxoplasma antigen in the brains of congenitally infected mice.","authors":"J Hay,&nbsp;D I Graham,&nbsp;G N Dutton,&nbsp;S Logan","doi":"10.1007/BF00925482","DOIUrl":"https://doi.org/10.1007/BF00925482","url":null,"abstract":"<p><p>The peroxidase anti-peroxidase immunocytochemical staining method was used to identify Toxoplasma antigen in paraffin embedded sections of the brains of 22 mice congenitally infected with the parasite. Intact Toxoplasma tissue cysts were readily demonstrated in the brain in all cases. In 4 of the 22 infected mice there was evidence of rupture of the cyst wall and/or presence of extra-cystic Toxoplasma antigen. Further support for the extra-cystic location of Toxoplasma antigen was obtained by electron microscopy of reprocessed tissue which revealed endozoites in the area immediately surrounding a ruptured cyst. The possible implications of these findings in relation to the pathogenesis of congenital toxoplasmic meningo-encephalitis are discussed.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 5","pages":"609-15"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925482","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14657092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Immunoelectron microscopy shows that the 80,000-dalton antigen of Plasmodium falciparum merozoites is localized in the surface coat. 免疫电镜显示,恶性疟原虫子体的80000道尔顿抗原定位于表面涂层。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925490
H G Heidrich, M Matzner, A Miettinen-Baumann, W Strych
{"title":"Immunoelectron microscopy shows that the 80,000-dalton antigen of Plasmodium falciparum merozoites is localized in the surface coat.","authors":"H G Heidrich,&nbsp;M Matzner,&nbsp;A Miettinen-Baumann,&nbsp;W Strych","doi":"10.1007/BF00925490","DOIUrl":"https://doi.org/10.1007/BF00925490","url":null,"abstract":"","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 5","pages":"681-3"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925490","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14657095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
In memoriam Ernest Bueding (1910-1986). 纪念欧内斯特·布丁(1910-1986)。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00925494
H J Saz, R P Saz
{"title":"In memoriam Ernest Bueding (1910-1986).","authors":"H J Saz,&nbsp;R P Saz","doi":"10.1007/BF00925494","DOIUrl":"https://doi.org/10.1007/BF00925494","url":null,"abstract":"","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 5","pages":"697-9"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00925494","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14657804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of diethylcarbamazine on the motility of Angiostrongylus cantonensis and Dirofilaria immitis. 二乙基卡马嗪对广东管圆线虫和免疫dirofilia蠕动的影响。
Zeitschrift fur Parasitenkunde (Berlin, Germany) Pub Date : 1986-01-01 DOI: 10.1007/BF00928748
M Terada, M Sano
{"title":"Effects of diethylcarbamazine on the motility of Angiostrongylus cantonensis and Dirofilaria immitis.","authors":"M Terada,&nbsp;M Sano","doi":"10.1007/BF00928748","DOIUrl":"https://doi.org/10.1007/BF00928748","url":null,"abstract":"<p><p>Effects of piperazine derivatives, especially of diethylcarbamazine (DEC) on adult Angiostrongylus cantonensis and Dirofilaria immitis were examined. Piperazine (3 X 10(-5)-10(-4) M) paralyzed A. cantonensis and the action was antagonized by picrotoxin. 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) (10(-5)-10(-4) M) caused contraction but little effect was produced by strychnine. An inhibitory effect on untreated preparations was caused by lower concentrations (3 X 10(-6)-10(-5) M) of diethylcarbamazine citrate (DEC) and also on the preparations contracted by eserine. A stimulatory effect was also seen when higher concentrations (10(-4)-3 X 10(-4) M) of this drug were applied to both preparations. The inhibitory action of DEC was antagonized by gabergic antagonists such as picrotoxin and bicuculline, but not by alpha-adrenergic antagonists like dibenamine and phentolamine. When the worm preparation was paralyzed by strychnine or hexylresorcinol (inhibitors of the release of acetylcholine in this worm), the stimulatory effect of DEC was blocked, but pyrantel (a nicotinic cholinergic agonist) contracted the paralyzed preparation. However, the effect of DEC on D. immitis (10(-7)-3 X 10(-4) M) was inhibitory, and this action was also antagonized by picrotoxin. These results suggest that the DEC inhibitory and stimulatory action is through the gabergic and cholinergic mechanisms in adult A. cantonensis and D. immitis.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 3","pages":"375-85"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00928748","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14836153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
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