{"title":"Effect of UV-irradiation, spleen cells and MLN cells on protective immunity against Angiostrongylus cantonensis infection in mice.","authors":"V R Kamath, S Menon, D M Renapurkar","doi":"10.1007/BF00931149","DOIUrl":null,"url":null,"abstract":"<p><p>The UV-irradiated larvae of Angiostrongylus cantonensis were used for inducing immunity in mice. A single oral dose of 100 infective UV-irradiated larvae exposed for 5 min or 15 min induced 91% and 97% protection against subsequent infection. Adoptive protection against A. cantonensis could also be transferred by spleen and mesenteric lymph node cells obtained from vaccinated mice.</p>","PeriodicalId":76856,"journal":{"name":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","volume":"72 2","pages":"221-6"},"PeriodicalIF":0.0000,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00931149","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Parasitenkunde (Berlin, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF00931149","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
The UV-irradiated larvae of Angiostrongylus cantonensis were used for inducing immunity in mice. A single oral dose of 100 infective UV-irradiated larvae exposed for 5 min or 15 min induced 91% and 97% protection against subsequent infection. Adoptive protection against A. cantonensis could also be transferred by spleen and mesenteric lymph node cells obtained from vaccinated mice.